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公开(公告)号：US20100081750A1
公开(公告)日：2010-04-01
申请号：US11457170
申请日：2006-07-13
Applicant: Patrick Guire , Kristin Taton , Jie Wen , Laurie R. Lawin
Inventor： Patrick Guire , Kristin Taton , Jie Wen , Laurie R. Lawin
IPC: C09D5/00
CPC classification number: C09D7/1233 , C08K5/0025 , C09D7/63 , Y10T428/31507 , Y10T428/31511 , Y10T428/31551 , Y10T428/31678 , Y10T428/31721 , Y10T428/31725 , Y10T428/31855 , Y10T428/31989 , Y10T428/31993
Abstract: The invention describes novel compositions that include a cross linking compound, a polymer and a 1 nm to about a 25 micron sized particle optionally with an oxide layer. In particular, the particle is a silica and one which has been pretreated with a silane.
Abstract translation: 本发明描述了包含交联化合物，聚合物和任选具有氧化物层的1nm至约25微米尺寸的颗粒的新型组合物。 特别地，颗粒是二氧化硅和已经用硅烷预处理的颗粒。
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公开(公告)号：US20080039343A1
公开(公告)日：2008-02-14
申请号：US11682526
申请日：2007-03-06
Applicant: Patrick Guire , Kristin Taton , John Wall
Inventor： Patrick Guire , Kristin Taton , John Wall
CPC classification number: B82Y30/00 , B01J19/0046 , B01J2219/00466 , B01J2219/005 , B01J2219/00576 , B01J2219/00585 , B01J2219/0061 , B01J2219/00612 , B01J2219/00619 , B01J2219/00637 , B01J2219/00648 , B01J2219/00659 , B01J2219/00725 , B82Y5/00 , B82Y10/00 , C12Q1/6837 , G01N33/54366 , Y10S530/81 , Y10S530/811 , Y10S530/815 , Y10S530/816 , C12Q2563/149
Abstract: Arrays including microparticles having probe and marker moieties are used for the detection of a target in a sample. Microparticles are randomly immobilized on at least a portion of a substrate. A detection scheme is performed to detect the marker associated with the microparticle and the identity of the probe, and any target bound to the probe.
Abstract translation: 包括具有探针和标记物部分的微粒的阵列用于检测样品中的靶。 微粒随机固定在底物的至少一部分上。 执行检测方案以检测与微粒相关的标记和探针的身份以及与探针结合的任何靶标。
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公开(公告)号：US07989619B2
公开(公告)日：2011-08-02
申请号：US11457170
申请日：2006-07-13
Applicant: Patrick Guire , Kristin Taton , Jie Wen , Laurie R. Lawin
Inventor： Patrick Guire , Kristin Taton , Jie Wen , Laurie R. Lawin
IPC: C07D251/32 , C07D251/34 , C08K5/3492 , C09K11/06
CPC classification number: C09D7/1233 , C08K5/0025 , C09D7/63 , Y10T428/31507 , Y10T428/31511 , Y10T428/31551 , Y10T428/31678 , Y10T428/31721 , Y10T428/31725 , Y10T428/31855 , Y10T428/31989 , Y10T428/31993
Abstract: The invention describes novel compositions that include a cross linking compound, a polymer and a 1 nm to about a 25 micron sized particle optionally with an oxide layer. In particular, the particle is a silica and one which has been pretreated with a silane.
Abstract translation: 本发明描述了包含交联化合物，聚合物和任选具有氧化物层的1nm至约25微米尺寸的颗粒的新型组合物。 特别地，颗粒是二氧化硅和已经用硅烷预处理的颗粒。
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4.发明授权公开(公告)号：US07772393B2
公开(公告)日：2010-08-10
申请号：US11423503
申请日：2006-06-12
Applicant: Patrick Guire , Kristin Taton , Jie Wen
Inventor： Patrick Guire , Kristin Taton , Jie Wen
IPC: C07D251/32 , C07D251/34 , C08K5/3492 , C09K11/06
CPC classification number: C07D251/30 , C07C275/10 , C07D251/34 , C09D139/08
Abstract: The invention describes novel crosslinking compounds that include photoactivatable moieties. Several families of compounds are disclosed that can include one or more hydrophilic moieties that help to solubilize the compounds in aqueous environments.
Abstract translation: 本发明描述了包含可光活化部分的新型交联化合物。 公开了几种化合物家族，其可以包括一种或多种有助于将化合物溶解在水性环境中的亲水部分。
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公开(公告)号：US20060024350A1
公开(公告)日：2006-02-02
申请号：US11165884
申请日：2005-06-24
Applicant: Signe Varner , Patrick Guire , Kristin Taton , Jie Wen , Nathan Beeley , Laurie Lawin , Robert Hergenrother , Ralph Chappa , Aron Anderson
Inventor： Signe Varner , Patrick Guire , Kristin Taton , Jie Wen , Nathan Beeley , Laurie Lawin , Robert Hergenrother , Ralph Chappa , Aron Anderson
IPC: A61F2/00
CPC classification number: A61K9/0051 , A61F9/0017 , A61F2210/0004 , A61L31/06 , C08L67/025
Abstract: The invention provides implantable medical devices that are fabricated of biodegradable materials for delivery of bioactive agent to limited access regions of a patient's body, such as the eye. The invention further provides methods of treatment utilizing the devices.
Abstract translation: 本发明提供了由可生物降解材料制成的植入式医疗装置，用于将生物活性剂递送到患者身体如眼睛的有限进入区域。 本发明还提供了利用这些装置的治疗方法。
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Patent Agency Ranking
公开(公告)号：US20060018948A1
公开(公告)日：2006-01-26
申请号：US11165993
申请日：2005-06-24
Applicant: Patrick Guire , Kristin Taton , Jie Wen , David DeWitt , Robert Hergenrother , Aron Anderson
Inventor： Patrick Guire , Kristin Taton , Jie Wen , David DeWitt , Robert Hergenrother , Aron Anderson
IPC: A61F2/00
CPC classification number: A61L31/06 , A61L31/148 , C08L67/025 , C08L71/02
Abstract: The invention provides implantable intraluminal medical devices that are fabricated of biodegradable materials. The invention further provides methods of treatment utilizing the devices.
Abstract translation: 本发明提供了由可生物降解材料制成的可植入管腔内医疗装置。 本发明还提供了利用这些装置的治疗方法。
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公开(公告)号：US20070003707A1
公开(公告)日：2007-01-04
申请号：US11423503
申请日：2006-06-12
Applicant: Patrick Guire , Kristin Taton , Jie Wen
Inventor： Patrick Guire , Kristin Taton , Jie Wen
IPC: C08F2/48 , C07D239/02
CPC classification number: C07D251/30 , C07C275/10 , C07D251/34 , C09D139/08
Abstract: The invention describes novel crosslinking compounds that include photoactivatable moieties. Several families of compounds are disclosed that can include one or more hydrophilic moieties that help to solubilize the compounds in aqueous environments.
Abstract translation: 本发明描述了包含可光活化部分的新型交联化合物。 公开了几种化合物家族，其可以包括一种或多种有助于将化合物溶解在水性环境中的亲水部分。
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公开(公告)号：US08496857B2
公开(公告)日：2013-07-30
申请号：US13167104
申请日：2011-06-23
Applicant: Patrick E. Guire , Kristin Taton , Jie Wen , Laurie R. Lawin
Inventor： Patrick E. Guire , Kristin Taton , Jie Wen , Laurie R. Lawin
IPC: C08K5/06 , C08K5/07 , C08K5/34 , C08L101/02 , C08L101/06 , C07C43/02 , C07C49/00
CPC classification number: C09D7/1233 , C08K5/0025 , C09D7/63 , Y10T428/31507 , Y10T428/31511 , Y10T428/31551 , Y10T428/31678 , Y10T428/31721 , Y10T428/31725 , Y10T428/31855 , Y10T428/31989 , Y10T428/31993
Abstract: The invention describes novel compositions that include a cross linking compound, a polymer and a 1 nm to about a 25 micron sized particle optionally with an oxide layer. In particular, the particle is a silica and one which has been pretreated with a silane.
Abstract translation: 本发明描述了包含交联化合物，聚合物和任选具有氧化物层的1nm至约25微米尺寸的颗粒的新型组合物。 特别地，颗粒是二氧化硅和已经用硅烷预处理的颗粒。
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9.发明授权公开(公告)号：US08487137B2
公开(公告)日：2013-07-16
申请号：US12831673
申请日：2010-07-07
Applicant: Patrick E. Guire , Kristin Taton , Jie Wen
Inventor： Patrick E. Guire , Kristin Taton , Jie Wen
IPC: C07C49/172 , C07C225/10 , C08F2/46 , C08J3/28
CPC classification number: C07D251/30 , C07C275/10 , C07D251/34 , C09D139/08
Abstract: The invention describes novel crosslinking compounds that include photoactivatable moieties. Several families of compounds are disclosed that can include one or more hydrophilic moieties that help to solubilize the compounds in aqueous environments.
Abstract translation: 本发明描述了包含可光活化部分的新型交联化合物。 公开了几种化合物家族，其可以包括一种或多种有助于将化合物溶解在水性环境中的亲水部分。
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公开(公告)号：US20120258313A1
公开(公告)日：2012-10-11
申请号：US13518337
申请日：2010-12-21
Applicant: Jie Wen , Kristin Taton , Laurie Lawin , William Knopke , Eric Guire , Patrick Guire
Inventor： Jie Wen , Kristin Taton , Laurie Lawin , William Knopke , Eric Guire , Patrick Guire
CPC classification number: C08F8/42 , A61L29/06 , A61L29/085 , A61L29/14 , A61L29/16 , A61L31/022 , A61L31/06 , A61L31/10 , A61L31/14 , A61L31/16 , A61L33/0005 , A61L2300/404 , A61L2300/42 , A61L2400/10 , A61L2420/02 , A61L2420/08 , B05D3/06 , C08F8/28 , C08F8/30 , C08F267/04 , C09D131/00 , C09D135/00 , Y10T428/31507 , Y10T428/31511 , Y10T428/31573 , Y10T428/31598 , Y10T428/31663 , Y10T428/31667 , Y10T428/31721 , Y10T428/3175 , Y10T428/31797 , Y10T428/31855 , Y10T428/31884 , Y10T428/31909 , Y10T428/31913 , Y10T428/31928 , C08F222/06
Abstract: The invention describes novel coating agents that include a polymer, one or more latent reactive groups and one or more noncovalent linking groups, the noncovalent linking groups selected to interact with a substrate to which the coating agent is applied. The coating agents are useful for providing a coating that can be further functionalized (for example, by application of additional coating layers), or for providing desirable properties to a surface.
Abstract translation: 本发明描述了新颖的涂层剂，其包括聚合物，一个或多个潜在反应性基团和一个或多个非共价连接基团，所选择的非共价连接基团与施加涂覆剂的基底相互作用。 涂层剂可用于提供可以进一步官能化的涂层（例如，通过施加额外的涂层），或用于为表面提供所需的性质。
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