公开(公告)号：US08372536B2

公开(公告)日：2013-02-12

申请号：US12789707

申请日：2010-05-28

Applicant: Man-Seok Han ,  Eui-Hwan Song ,  Sumihito Ishida ,  Satoshi Narukawa ,  Jin-Kyu Hong ,  Jun-Sik Kim ,  Kyeu-Yoon Sheem ,  Tae-Keun Kim ,  Mee-Young Lee

Inventor： Man-Seok Han ,  Eui-Hwan Song ,  Sumihito Ishida ,  Satoshi Narukawa ,  Jin-Kyu Hong ,  Jun-Sik Kim ,  Kyeu-Yoon Sheem ,  Tae-Keun Kim ,  Mee-Young Lee

IPC: H01M2/00 ,  H01M6/46

CPC classification number: H01M2/1061 ,  H01M2/0277 ,  H01M2/0285 ,  H01M2/0287 ,  H01M2/204 ,  H01M4/661

Abstract: A battery module for a rechargeable battery. The battery module has low contact resistance and includes: a plurality of electrode assemblies incorporating a positive electrode, a negative electrode and a separator disposed between the positive electrode and the negative electrode; a housing installed with the electrode assembly; and at least one conductive barrier inserted in the housing thereby dividing the space inside the housing, and electrically connecting the plurality of electrode assemblies.

Abstract translation: 用于充电电池的电池模块。 电池模块具有低接触电阻，并且包括：多个电极组件，其包括设置在正极和负极之间的正极，负极和隔板; 安装有电极组件的壳体; 以及至少一个导电屏障插入壳体中，从而将壳体内部的空间分开，并电连接多个电极组件。

公开(公告)号：US08722110B2

公开(公告)日：2014-05-13

申请号：US13820474

申请日：2011-08-30

Applicant: Kyung Seop Ahn ,  Ok-Kyoung Kwon ,  Sei Ryang Oh ,  Jung Hee Kim ,  Hyeong Kyu Lee ,  Mee-Young Lee ,  Hwa-Young Son ,  Kyoung-Youl Lee ,  Soo Yong Kim ,  Giselle Tomayo-Castillo ,  Katia Rosales-Ovares ,  Rodrigo Gamez-Lobo

Inventor： Kyung Seop Ahn ,  Ok-Kyoung Kwon ,  Sei Ryang Oh ,  Jung Hee Kim ,  Hyeong Kyu Lee ,  Mee-Young Lee ,  Hwa-Young Son ,  Kyoung-Youl Lee ,  Soo Yong Kim ,  Giselle Tomayo-Castillo ,  Katia Rosales-Ovares ,  Rodrigo Gamez-Lobo

IPC: A01N65/00

CPC classification number: A61K36/44

Abstract: Disclosed is a pharmaceutical composition for the prophylaxis and therapy of inflammatory diseases, allergic diseases, or asthma, comprising a velvet apple (Diospyros blancoi A. DC.) extract as an active ingredient. Having the inhibitory activity against the nuclear translocation of NF-κB, whose level is rapidly elevated in response to inflammatory stimuli, the velvet apple extract can suppress the production of NO and PGE2, the expression of iNOS and COX-2, and the release of IL-1β and TNF-α, and can significantly down regulate Th2-mediated IL-4 and IL-13 production. In addition, the extract was found to inhibit the activation of eosinophils in bronchoalveolar lavage fluid, and to suppress the secretion of immunoglobulins and chemokines in bronchoalveolar lavage fluid and blood, as measured by in vivo tests on an ovalbumin-induced asthma mouse model. Therefore, the extract can be used in the method for preventing or treating various inflammatory disorders, allergic diseases, or asthma.

Abstract translation: 公开了一种用于预防和治疗炎性疾病，过敏性疾病或哮喘的药物组合物，其包含天鹅绒苹果（Diospyros blancoi A.DC。）提取物作为活性成分。 天鹅绒苹果提取物对NF-κB的核易位具有抑制活性，其水平迅速升高，可抑制NO和PGE2的产生，iNOS和COX-2的表达，以及 释放IL-1和bgr; 和TNF-α，并可显着下调Th2介导的IL-4和IL-13产生。 此外，发现提取物抑制支气管肺泡灌洗液中嗜酸性粒细胞的活化，并且通过卵清蛋白诱导的哮喘小鼠模型的体内试验测量，抑制支气管肺泡灌洗液和血液中免疫球蛋白和趋化因子的分泌。 因此，提取物可用于预防或治疗各种炎性疾病，过敏性疾病或哮喘的方法。

公开(公告)号：US20130323331A1

公开(公告)日：2013-12-05

申请号：US13985533

申请日：2012-02-07

Applicant: Sei Ryang Oh ,  Kyung Seop Ahn ,  Ok-Kyoung Kwon ,  Hyeong Kyu Lee ,  Joongku Lee ,  Hyouk Joung ,  Mee-Young Lee ,  Hwa-Young Son ,  Kyoung-youl Lee ,  Sang Woo Lee ,  Hang Jin ,  Wan Yi Li

Inventor： Sei Ryang Oh ,  Kyung Seop Ahn ,  Ok-Kyoung Kwon ,  Hyeong Kyu Lee ,  Joongku Lee ,  Hyouk Joung ,  Mee-Young Lee ,  Hwa-Young Son ,  Kyoung-youl Lee ,  Sang Woo Lee ,  Hang Jin ,  Wan Yi Li

IPC: A61K36/61

CPC classification number: A61K36/61

Abstract: The present invention relates to a pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma comprising the extract of Decaspermum fruticosum as an active ingredient. The extract of Decaspermum fruticosum of the present invention inhibited the increase of eosinophils in bronchoalveolar lavage fluid of the ovalbumin-induced asthma animal model, had the activity of inhibiting the secretions of immunoglobulin and chemokine (Eotaxin) in bronchoalveolar lavage fluid and blood, and inhibited the secretions of NO and TNF-α in macrophages. Therefore, the extract of Decaspermum fruticosum of the present invention can be effectively used as an active ingredient of a pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma, and of a health functional food for the prevention and improvement of inflammatory disease or asthma.

Abstract translation: 本发明涉及一种用于预防和治疗炎症性疾病或哮喘的药物组合物，其包含作为活性成分的Dececpermum fruticosum的提取物。 本发明的Decaspermum fruticosum的提取物抑制卵清蛋白诱导的哮喘动物模型的支气管肺泡灌洗液中嗜酸性粒细胞的增加，具有抑制支气管肺泡灌洗液和血液中免疫球蛋白和趋化因子（Eotaxin）分泌的活性，并被抑制 NO和TNF-α在巨噬细胞中的分泌。 因此，本发明的Decaspermum fruticosum的提取物可以有效地用作预防和治疗炎性疾病或哮喘的药物组合物的活性成分，以及用于预防和改善炎性疾病或哮喘的健康功能食品 。

公开(公告)号：US20090104490A1

公开(公告)日：2009-04-23

申请号：US12176153

申请日：2008-07-18

Applicant: Seung-Shik Shin ,  Ho-Jin Kweon ,  Mee-Young Lee

Inventor： Seung-Shik Shin ,  Ho-Jin Kweon ,  Mee-Young Lee

IPC: H01M8/04 ,  H01M8/00

CPC classification number: H01M8/04559 ,  H01M8/04223 ,  H01M8/04225 ,  H01M8/04302 ,  H01M8/0488

Abstract: A fuel cell system is provided including a fuel cell stack and a starting controller. The fuel cell stack has output terminals for applying an output voltage. The starting controller is configured to control the output voltage applied across the output terminals of the fuel cell stack during a starting period to be a starting voltage lower than a rated voltage.

Abstract translation: 提供了包括燃料电池堆和启动控制器的燃料电池系统。 燃料电池堆具有用于施加输出电压的输出端子。 启动控制器被配置为控制在启动期间施加在燃料电池堆的输出端子上的输出电压为低于额定电压的启动电压。

公开(公告)号：US20080311463A1

公开(公告)日：2008-12-18

申请号：US12130420

申请日：2008-05-30

Applicant: Jun-Young PARK ,  Seung-shik Shin ,  Mee-young Lee ,  Tae-keun Kim

Inventor： Jun-Young PARK ,  Seung-shik Shin ,  Mee-young Lee ,  Tae-keun Kim

IPC: H01M4/96

CPC classification number: H01M8/0245 ,  H01M8/0234 ,  H01M8/0239 ,  H01M8/0243 ,  H01M8/04119 ,  H01M8/1004 ,  H01M8/1011 ,  Y02E60/523

Abstract: A membrane electrode assembly in a fuel cell system includes a cathode electrode that includes a support layer; a catalyst layer; and a first carbon layer and second carbon layer between the support layer and the catalyst layer, the first carbon layer having a relatively higher porosity and the second carbon layer having a relatively lower porosity. Therefore, the membrane electrode assembly maintains good ion conductivity in the polymer electrolyte membrane by suppressing the movement of water molecules from the polymer electrolyte membrane to the cathode electrode using a water pressure between two carbon layers having different porosity. Also, a flooding phenomenon in the cathode electrode is prevented, thereby maintaining the smooth movement of the oxidizing agent in the cathode.

Abstract translation: 燃料电池系统中的膜电极组件包括：包括支撑层的阴极; 催化剂层; 以及在所述支撑层和所述催化剂层之间的第一碳层和第二碳层，所述第一碳层具有相对较高的孔隙率，并且所述第二碳层具有相对较低的孔隙率。 因此，通过使用具有不同孔隙率的两个碳层之间的水压抑制水分子从聚合物电解质膜向阴极的移动，膜电极组件在聚合物电解质膜中保持良好的离子传导性。 此外，防止阴极中的淹水现象，从而保持氧化剂在阴极中的平稳移动。

公开(公告)号：US08883226B2

公开(公告)日：2014-11-11

申请号：US13985533

申请日：2012-02-07

Applicant: Sei Ryang Oh ,  Kyung Seop Ahn ,  Ok-Kyoung Kwon ,  Hyeong Kyu Lee ,  Joongku Lee ,  Hyouk Joung ,  Mee-Young Lee ,  Hwa-Young Son ,  Kyoung-youl Lee ,  Sang Woo Lee ,  Hang Jin ,  Wan Yi Li

Inventor： Sei Ryang Oh ,  Kyung Seop Ahn ,  Ok-Kyoung Kwon ,  Hyeong Kyu Lee ,  Joongku Lee ,  Hyouk Joung ,  Mee-Young Lee ,  Hwa-Young Son ,  Kyoung-youl Lee ,  Sang Woo Lee ,  Hang Jin ,  Wan Yi Li

IPC: A61K36/31

CPC classification number: A61K36/61

Abstract: A pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma comprising the extract of Decaspermum fruticosum as an active ingredient. The extract of Decaspermum fruticosum of the present invention inhibited the increase of eosinophils in bronchoalveolar lavage fluid of the ovalbumin induced asthma animal model, had the activity of inhibiting the secretions of immunoglobulin and chemokine (Eotaxin) in bronchoalveolar lavage fluid and blood, and inhibited the secretions of NO and TNF-α in macrophages. Therefore, the extract of Decaspermum fruticosum of the present invention can be effectively used as an active ingredient of a pharmaceutical composition for the prevention and treatment of inflammatory disease or asthma, and of a health functional food for the prevention and improvement of inflammatory disease or asthma.

Abstract translation: 一种用于预防和治疗炎症性疾病或哮喘的药物组合物，其包含作为活性成分的Dececpermum fruticosum的提取物。 本发明的Decaspermum fruticosum的提取物抑制卵清蛋白诱导的哮喘动物模型的支气管肺泡灌洗液中嗜酸性粒细胞的增加，具有抑制支气管肺泡灌洗液和血液中免疫球蛋白和趋化因子（Eotaxin）分泌的活性，并抑制 巨噬细胞中NO和TNF-α的分泌。 因此，本发明的Decaspermum fruticosum的提取物可以有效地用作预防和治疗炎性疾病或哮喘的药物组合物的活性成分，以及用于预防和改善炎性疾病或哮喘的健康功能食品 。

公开(公告)号：US08647768B2

公开(公告)日：2014-02-11

申请号：US13047739

申请日：2011-03-14

Applicant: Kyeu-Yoon Sheem ,  Mee-Young Lee ,  Sumihito Ishida ,  Eui-Hwan Song

Inventor： Kyeu-Yoon Sheem ,  Mee-Young Lee ,  Sumihito Ishida ,  Eui-Hwan Song

IPC: H01M4/60

CPC classification number: H01M4/625 ,  H01G11/32 ,  H01M4/13 ,  H01M10/052 ,  Y02E60/13

Abstract: Disclosed are a positive active material composition for an electrochemical device, a positive electrode, and an electrochemical device including the same. The positive active material composition includes: a carbon-based additive including a hydroxyl group (—OH) and an enol group (—C═C—OH) on the surface, having a peak area ratio (OH/C═COH) of a hydroxyl group peak area and an enol group peak area of an infrared spectroscopy (FT-IR) spectrum ranging from about 0.5 to about 10, having a specific surface area of about 50 m2/g to about 3000 m2/g, and having an oxygen-containing heterogeneous element in a content of less than about 15 wt %; a positive active material; a conductive material; and a binder.

Abstract translation: 公开了一种用于电化学装置，正电极和包括其的电化学装置的正极活性材料组合物。 正极活性物质组合物包括：表面具有羟基（-OH）和烯醇基（-C = C-OH）的碳基添加剂，其表面积的峰面积比（OH / C = COH） 羟基峰面积和范围为约0.5至约10的红外光谱（FT-IR）光谱的烯醇基峰面积，比表面积为约50m 2 / g至约3000m 2 / g，并具有氧 含量小于约15重量％的异质元素; 正极活性物质; 导电材料; 和粘合剂。

公开(公告)号：US20130164395A1

公开(公告)日：2013-06-27

申请号：US13820474

申请日：2011-08-30

Applicant: Kyung Seop Ahn ,  Ok-Kyoung Kwon ,  Sei Ryang Oh ,  Jung Hee Kim ,  Hyeong Kyu Lee ,  Mee-Young Lee ,  Hwa-Young Son ,  Kyoung-Youl Lee ,  Soo Yong Kim ,  Giselle Tomayo-Castillo ,  Katia Rosales-Ovares ,  Rodrigo Gamez-Lobo

Inventor： Kyung Seop Ahn ,  Ok-Kyoung Kwon ,  Sei Ryang Oh ,  Jung Hee Kim ,  Hyeong Kyu Lee ,  Mee-Young Lee ,  Hwa-Young Son ,  Kyoung-Youl Lee ,  Soo Yong Kim ,  Giselle Tomayo-Castillo ,  Katia Rosales-Ovares ,  Rodrigo Gamez-Lobo

IPC: A61K36/44

CPC classification number: A61K36/44

Abstract: Disclosed is a pharmaceutical composition for the prophylaxis and therapy of inflammatory diseases, allergic diseases, or asthma, comprising a velvet apple (Diospyros blancoi A. DC.) extract as an active ingredient. Having the inhibitory activity against the nuclear translocation of NF-κB, whose level is rapidly elevated in response to inflammatory stimuli, the velvet apple extract can suppress the production of NO and PGE2, the expression of iNOS and COX-2, and the release of IL-1β and TNF-α, and can significantly down regulate Th2-mediated IL-4 and IL-13 production. In addition, the extract was found to inhibit the activation of eosinophils in bronchoalveolar lavage fluid, and to suppress the secretion of immunoglobulins and chemokines in bronchoalveolar lavage fluid and blood, as measured by in vivo tests on an ovalbumin-induced asthma mouse model. Therefore, the extract can be used in the method for preventing or treating various inflammatory disorders, allergic diseases, or asthma.

Abstract translation: 公开了一种用于预防和治疗炎性疾病，过敏性疾病或哮喘的药物组合物，其包含天鹅绒苹果（Diospyros blancoi A.DC。）提取物作为活性成分。 天鹅绒苹果提取物对NF-κB的核易位具有抑制作用，NF-κB的水平随着炎症刺激而迅速升高，可抑制NO和PGE2的产生，iNOS和COX-2的表达，以及释放 IL-1β和TNF-α，并能显着下调Th2介导的IL-4和IL-13产生。 此外，发现提取物抑制支气管肺泡灌洗液中嗜酸性粒细胞的活化，并且通过卵清蛋白诱导的哮喘小鼠模型的体内试验测量，抑制支气管肺泡灌洗液和血液中免疫球蛋白和趋化因子的分泌。 因此，提取物可用于预防或治疗各种炎性疾病，过敏性疾病或哮喘的方法。

公开(公告)号：US20120070745A1

公开(公告)日：2012-03-22

申请号：US13149627

申请日：2011-05-31

Applicant: Sumihito ISHIDA ,  Jong-Ki Lee ,  Kyeu-Yoon Sheem ,  Mee-Young Lee

Inventor： Sumihito ISHIDA ,  Jong-Ki Lee ,  Kyeu-Yoon Sheem ,  Mee-Young Lee

IPC: H01M4/583 ,  H01M4/58

CPC classification number: H01M4/38 ,  H01M4/134 ,  H01M4/624 ,  H01M10/0525

Abstract: Disclosed are a negative active material for a rechargeable lithium battery and a rechargeable lithium battery including the same. The active material includes a silicon-containing compound represented by the following Chemical Formula 1. SiCx   [Chemical Formula 1] wherein, 0.05≦x≦1.5; wherein the compound is substantially amorphous.

Abstract translation: 公开了一种用于可再充电锂电池的负极活性材料和包括其的可再充电锂电池。 活性材料包括由以下化学式1表示的含硅化合物.SiCx [化学式1]其中，0.05＆lt; 1; x＆lt; ll; 1.5; 其中所述化合物基本上是无定形的。

公开(公告)号：US20080199758A1

公开(公告)日：2008-08-21

申请号：US11956180

申请日：2007-12-13

Applicant: Seung-shik SHIN ,  Ho-jin KWEON ,  Mee-young LEE ,  Tae-keun KIM

Inventor： Seung-shik SHIN ,  Ho-jin KWEON ,  Mee-young LEE ,  Tae-keun KIM

IPC: H01M4/92

CPC classification number: H01M8/1004 ,  H01M4/8657 ,  H01M4/92 ,  H01M4/926 ,  H01M8/0234 ,  H01M8/0247 ,  H01M8/0258 ,  H01M8/0276 ,  H01M8/04171 ,  H01M8/241

Abstract: A fuel cell includes: a fuel cell body; and a fuel supplier supplying fuel to the fuel cell body, wherein the fuel cell body includes: a membrane electrode assembly including an ion exchange membrane, an anode catalyst layer positioned at one surface of the ion exchange membrane, an anode gas diffusion layer positioned at one surface of the anode catalyst layer, and a cathode catalyst layer positioned at other surface of the ion exchange membrane; and a fuel flow field positioned at the one surface of the anode gas diffusion layer and supplying the fuel to the anode catalyst layer through the anode diffusion layer.

Abstract translation: 燃料电池包括：燃料电池体; 向该燃料电池主体供给燃料的燃料供给体，其特征在于，所述燃料电池体具备：离子交换膜，位于所述离子交换膜的一个表面的阳极催化剂层的阳极气体扩散层， 阳极催化剂层的一个表面和位于离子交换膜的另一个表面的阴极催化剂层; 以及燃料流场，其位于阳极气体扩散层的一个表面，并通过阳极扩散层将燃料供给阳极催化剂层。