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    Apparatus and method for processing micro-V grooves
    3.
    发明授权
    Apparatus and method for processing micro-V grooves 失效
    微V槽加工装置及方法

    公开(公告)号：US06478661B2

    公开(公告)日：2002-11-12

    申请号：US09794909

    申请日：2001-02-28

    申请人： Hitoshi Ohmori ,  Noboru Ebizuka ,  Yutaka Yamagata ,  Shinya Morita ,  Sei Moriyasu ,  Muneaki Asami

    发明人： Hitoshi Ohmori ,  Noboru Ebizuka ,  Yutaka Yamagata ,  Shinya Morita ,  Sei Moriyasu ,  Muneaki Asami

    IPC分类号： B24B100

    CPC分类号： B24B53/001 ,  B24B13/015 ,  B24B19/028 ,  B24B53/02

    摘要： A voltage is applied between a cylindrical cutting grindstone 2 that rotates about a vertical axis Y and a cylindrical truing grindstone 6 that rotates about a horizontal axis X. The vertical outer surface 2a and the horizontal lower surface 2b of the cutting grindstone are trued by a plasma discharge. Then without applying the voltage, the cutting grindstone 2 is trued mechanically by the truing grindstone 6, and while the outer periphery and lower surface of the cutting grindstone are dressed electrolytically, the outer periphery and lower surface are made to contact a workpiece 1 and process a micro-V groove. This method makes it possible to produce an immersion grating with a high resolution using hard, brittle materials such as germanium, gallium arsenide and lithium niobate.

    摘要翻译： 在围绕垂直轴线Y旋转的圆筒形磨石2和围绕水平轴线X旋转的圆柱形修整磨石6之间施加电压。切割磨石的垂直外表面2a和水平下表面2b由 等离子体放电。 然后在不施加电压的情况下，通过修整磨石6机械地修整切割磨石2，并且当切割磨石的外周和下表面被电解时，使外周和下表面接触工件1和工艺 一个微V槽。 该方法使得可以使用诸如锗，砷化镓和铌酸锂的硬的脆性材料来生产具有高分辨率的浸没光栅。

    Sustained releasable parenteral pharmaceutical preparations and method of producing the same
    4.
    发明授权
    Sustained releasable parenteral pharmaceutical preparations and method of producing the same 失效
    持续可释放的肠胃外药物制剂及其制备方法

    公开(公告)号：US5628993A

    公开(公告)日：1997-05-13

    申请号：US294972

    申请日：1994-08-24

    申请人： Yutaka Yamagata ,  Katsumi Iga ,  Hiroaki Okada

    发明人： Yutaka Yamagata ,  Katsumi Iga ,  Hiroaki Okada

    IPC分类号： A61K9/14 ,  A61K9/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22 ,  A61K9/26 ,  A61K9/70 ,  A61K38/00 ,  A61K38/20 ,  A61K38/21 ,  A61K38/28 ,  A61K47/14 ,  A61K38/02

    CPC分类号： A61K9/2013 ,  A61K38/2013 ,  A61K38/212 ,  A61K38/28 ,  A61K9/1617 ,  A61K9/70 ,  A61K9/0024

    摘要： A parenteral pharmaceutical preparation comprises a matrix containing a physiologically active peptide or protein and a polyglycerol diester of a saturated fatty acid, and the matrix is in a solid form at room temperature. The molecular weight of the physiologically active peptide or protein is 2,000 dalton or more. The saturated fatty acid includes fatty acids having about 16 to 30 carbon atoms such as palmitic acid, stearic acid, etc. The matrix may be in a pillar or granular form. The parenteral pharmaceutical preparation can be used as an injectable solid administered subcutaneously or intramuscularly (for example, a pellet or tablet for implantation), a suppository or the like, and can release the physiologically active peptide or protein sustainedly for a prolonged period of one week or more.

    摘要翻译： 肠胃外药物制剂包含含有生理活性肽或蛋白质的基质和饱和脂肪酸的聚甘油二酯，并且所述基质在室温下为固体形式。 生理活性肽或蛋白质的分子量为2,000道尔顿或更多。 饱和脂肪酸包括具有约16至30个碳原子的脂肪酸，例如棕榈酸，硬脂酸等。基质可以是柱状或颗粒形式。 肠胃外药物制剂可以用作皮下或肌肉内给药的可注射固体（例如，用于植入的丸粒或片剂），栓剂等，并且可以持续释放生理活性肽或蛋白质一周的长时间 或者更多。

    Immobilizing method, immobilization apparatus, and microstructure manufacturing method
    7.
    发明申请
    Immobilizing method, immobilization apparatus, and microstructure manufacturing method 审中-公开
    固定方法，固定装置和微结构制造方法

    公开(公告)号：US20070157880A1

    公开(公告)日：2007-07-12

    申请号：US10546008

    申请日：2004-02-19

    申请人： Akihiko Tanioka ,  Yutaka Yamagata ,  Kozo Inoue

    发明人： Akihiko Tanioka ,  Yutaka Yamagata ,  Kozo Inoue

    IPC分类号： B05C5/02

    CPC分类号： B05B5/087 ,  B05B5/025

    摘要： An immobilization method, an apparatus, and a manufacturing method of a microstructure are provided, where the method including the electrospray step by which a solution containing at least one objective substance is supplied to a capillary; and immobilization step by which the objective substance in the solution atomized in the electrospray step is immobilized on an object, which is to be coated and has an arbitrary shape, in a dried state by an electrostatic force while retaining functionality and/or activity of the objective substance, resulting in a thickness on the order of nanometers.

    摘要翻译： 提供一种微结构的固定方法，装置和制造方法，其中包括将含有至少一种目标物质的溶液供给毛细管的电喷雾步骤的方法; 以及固定步骤，其中在电喷雾步骤中雾化的溶液中的目标物质通过静电力固定在被涂覆并具有任意形状的物体上，同时保持其的功能和/或活性 目标物质，导致纳米级的厚度。

    Liquid treating equipment including a storage vessel and a discharge vessel
    8.
    发明授权
    Liquid treating equipment including a storage vessel and a discharge vessel 失效
    液体处理设备，包括储存容器和放电容器

    公开(公告)号：US07189365B1

    公开(公告)日：2007-03-13

    申请号：US09674304

    申请日：2000-03-03

    申请人： Yutaka Yamagata ,  Tsunehiko Ozaki ,  Victor Morozov ,  Kozo Inoue

    发明人： Yutaka Yamagata ,  Tsunehiko Ozaki ,  Victor Morozov ,  Kozo Inoue

    IPC分类号： B01L3/02

    CPC分类号： G05D9/12 ,  Y10T137/7287 ,  Y10T137/7303 ,  Y10T137/731 ,  Y10T137/7313

    摘要： In a liquid treating equipment to maintain a small amount of liquid to a desired liquid level with constantly supplying an additional liquid into a small capacity vessel, a storage vessel 13 to store the small amount of liquid, an injection tube 16 to inject the small amount of liquid into the storage vessel 16, liquid supplying apparatus 23–25 to supply the small amount of liquid into the storage vessel through the injection tube, a flow path 15 of which one end is joined with the storage vessel, a discharge vessel 14, joined with the storage vessel 13 via the flow path, having a larger surface area than that of the storage vessel, a discharge tube 17 of which the discharging inlet is positioned at the same level position as a desired liquid level of the small amount of liquid in the storage vessel and liquid discharging apparatus 27–29 to discharge the liquid from the discharge vessel through the discharge tube are provided. Even though the liquid level in the discharge vessel is largely fluctuated, the liquid level in the storage vessel is almost never done.

    摘要翻译： 在液体处理设备中，将少量液体维持在期望的液面上，同时向小容量容器中供应额外的液体，存储容器13以储存少量液体，注射管16注入少量 的液体进入储存容器16，液体供应装置23-25通过注射管将少量液体供应到储存容器中，其一端与储存容器接合的流路15，放电容器14， 经由流路与储存容器13连接，具有比储存容器更大的表面积;排出管17，其排出口位于与少量液体的期望液面相同的水平位置 在存储容器和液体排出装置27-29中，通过放电管将液体从放电容器排出。 即使放电容器中的液位大大波动，储存容器中的液面几乎从未完成。

    Neutron beam control device and method manufacturing the control device
    10.
    发明申请
    Neutron beam control device and method manufacturing the control device 失效
    中子束控制装置及方法制造控制装置

    公开(公告)号：US20060226350A1

    公开(公告)日：2006-10-12

    申请号：US10516449

    申请日：2003-06-03

    申请人： Shinya Morita ,  Hitoshi Ohmori ,  Yutaka Yamagata ,  Hirohiko Shimizu ,  Takayuki Oku

    发明人： Shinya Morita ,  Hitoshi Ohmori ,  Yutaka Yamagata ,  Hirohiko Shimizu ,  Takayuki Oku

    IPC分类号： H05H3/02

    CPC分类号： G21K1/06 ,  G21K2201/068

    摘要： An apparatus for controlling a neutron beam includes a plurality of columnar prisms 1 that are made of a material having a refractive index of less than 1 for a neutron beam, and are arranged so as to be multi-layered. The columnar prisms 1 each have an approximately right-triangle-shaped section, and are three-dimensionally multi-layered such that respective surfaces 1a, 1b, 1c of the columnar prisms are in parallel to one another. Stick-shaped members 5 are made of the above material, the stick-shaped members 5 are set in a plurality of grooves formed on a jig 6 that have the same shape, and upper surfaces of the grooves are flattened at the same time.

    摘要翻译： 用于控制中子束的装置包括多个柱状棱镜1，其由中子束的折射率小于1的材料制成，并且被布置为多层。 柱状棱镜1各自具有近似三角形的截面，并且是三维多层的，使得柱状棱镜的各个表面1a，1b，1c彼此平行。 棒状构件5由上述材料制成，棒状构件5被设置在形成于具有相同形状的夹具6上的多个槽中，并且槽的上表面同时被平坦化。