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    Stable hydroalcoholic compositions
    3.
    发明申请
    Stable hydroalcoholic compositions 失效
    稳定的水醇组合物

    公开(公告)号：US20020142018A1

    公开(公告)日：2002-10-03

    申请号：US10075893

    申请日：2002-02-14

    Applicant: 3M Innovative Properties Company

    Inventor： Matthew T. Scholz ,  Robert A. Asmus ,  Jill R. Charpentier

    IPC: A61K007/00

    CPC classification number: A61K8/34 ,  A61K8/342 ,  A61K8/37 ,  A61K8/39 ,  A61K8/416 ,  A61K8/604 ,  A61K8/86 ,  A61Q17/005 ,  A61Q19/00 ,  Y10S514/846 ,  Y10S514/873 ,  Y10S514/944 ,  Y10S514/945 ,  Y10S514/946 ,  Y10S514/975

    Abstract: Disclosed is a composition including a lower alcohol and water in a weight ratio of about 35:65 to 100:0, between at least 0.5% and 8.0% by weight thickener system comprised of at least two emulsifiers, each emulsifier present in at least 0.05% by weight wherein the composition free of auxiliary thickeners has a viscosity of at least 4,000 centipoise at 23null C. and wherein each emulsifier is comprised of at least one hydrophobic group and at least one hydrophilic group. The composition is useful as a presurgical scrub replacement, a lotion or other hand preparation.

    Abstract translation: 公开了包含低级醇和水的组合物，其重量比为约35:65至100:0，至少0.5重量％至8.0重量％的由至少两种乳化剂组成的增稠剂体系，每种乳化剂存在于至少0.05 重量％，其中不含辅助增稠剂的组合物在23℃具有至少4,000厘泊的粘度，并且其中每个乳化剂由至少一个疏水基团和至少一个亲水基团组成。 组合物可用作术前洗刷替代物，洗剂或其他手制剂。

    Skin antiseptic composition dispenser and methods of use
    4.
    发明申请
    Skin antiseptic composition dispenser and methods of use 有权
    皮肤防腐剂组合物分配器及使用方法

    公开(公告)号：US20040068218A1

    公开(公告)日：2004-04-08

    申请号：US10263518

    申请日：2002-10-03

    Applicant: 3M Innovative Properties Company Office of Intellectual Property Counsel

    Inventor： Robert A. Davis ,  Matthew T. Scholz ,  Mark V. Johnson ,  Triet M. Lu ,  Robert A. Asmus ,  John D. Dell

    IPC: A61M035/00

    CPC classification number: A61M35/006

    Abstract: Skin antiseptic composition dispensers and methods of use are disclosed. The skin antiseptic composition dispenser may include a container with one or more walls that are substantially impermeable to ethylene oxide gas during normal ethylene oxide sterilization processes. In some embodiments, the container may include flexible walls free of metallic foil barrier layers. The containers may also include one or more vents in addition to one or more openings used to dispense the skin antiseptic composition within the container. The dispenser may include an applicator with a hydrophilic foam.

    Abstract translation: 公开了皮肤防腐剂组合物分配器和使用方法。 皮肤消毒组合物分配器可以包括具有一个或多个壁的容器，所述壁在正常环氧乙烷灭菌过程中基本上不渗透环氧乙烷气体。 在一些实施例中，容器可以包括没有金属箔阻挡层的柔性壁。 除了用于分配容器内的皮肤消毒组合物的一个或多个开口之外，容器还可以包括一个或多个通气口。 分配器可以包括具有亲水性泡沫的涂布器。

    Pharmaceutical formulation comprising an immune response modifier
    5.
    发明申请
    Pharmaceutical formulation comprising an immune response modifier 审中-公开
    包含免疫应答调节剂的药物制剂

    公开(公告)号：US20030199538A1

    公开(公告)日：2003-10-23

    申请号：US10306019

    申请日：2002-11-27

    Applicant: 3M Innovative Properties Company

    Inventor： Raymond D. Skwierczynski ,  Terri F. Busch ,  Amy L. Gust-Heiting ,  Mary Fretland ,  Matthew T. Scholz

    IPC: A61K031/4745 ,  A61K031/20

    CPC classification number: A61K31/437 ,  A61K9/0014 ,  A61K31/4355 ,  A61K31/4365 ,  A61K31/4375 ,  A61K31/4745 ,  A61K47/10 ,  A61K47/14 ,  A61K47/32 ,  A61K47/36 ,  A61K47/44

    Abstract: Pharmaceutical formulations comprising an immune response modifier (IRM) chosen from imidazoquinoline amines, imidazotetrahydroquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, 1,2-bridged imidazoquinoline amines, thiazolo-quinolineamines, oxazolo-quinolinamines, thiazolo-pyridinamines, oxazolo-pyridinamines, imidazonaphthyridine amines, tetrahydroimidazonaphthyridine amines, and thiazolonaphthyridine amines; a fatty acid; and a hydrophobic, aprotic component miscible with the fatty acid are useful for the treatment of dermal associated conditions. Novel topical formulations are provided. In one embodiment, the topical formulations are advantageous for treatment of actinic keratosis, postsurgical scars, basal cell carcinoma, atopic dermatitis, and warts.

    Abstract translation: 包含选自咪唑并喹啉胺，咪唑四氢喹啉胺，咪唑并吡啶胺，6,7-稠合的环烷基咪唑并吡啶胺，1,2-桥连的咪唑并喹啉胺，噻唑并喹啉胺，恶唑并喹啉胺，噻唑并 - 吡啶胺，恶唑啉 吡啶胺，咪唑并吡啶胺，四氢咪唑并吡啶胺和噻唑烷吡啶胺; 脂肪酸 并且与脂肪酸可混溶的疏水性非质子组分可用于治疗真皮相关病症。 提供新的局部制剂。 在一个实施方案中，局部制剂有利于治疗光化性角化病，术后瘢痕，基底细胞癌，特应性皮炎和疣。

    Antiseptic compositions and methods
    9.
    发明申请
    Antiseptic compositions and methods 有权
    防腐组合物和方法

    公开(公告)号：US20030194447A1

    公开(公告)日：2003-10-16

    申请号：US10051719

    申请日：2002-01-16

    Applicant: 3M Innovative Properties Company

    Inventor： Matthew T. Scholz ,  Danli Wang ,  Triet M. Lu ,  Dong-Wei Zhu

    IPC: A61K033/36

    CPC classification number: A61K31/79 ,  A01N59/12 ,  A61K47/12 ,  Y10S514/975 ,  A01N37/36 ,  A01N25/24 ,  A01N2300/00

    Abstract: Antiseptic compositions, as well as methods of making and using, wherein the compositions include: an antimicrobial agent selected from the group consisting of iodine (I2), an iodophor, and a combination thereof, wherein the antimicrobial agent is present in an amount sufficient to provide an available iodine concentration of at least about 0.25 wt-%; a hydroxycarboxylic acid buffer in an amount of at least about 5 wt-%; water; and an optionally substantive film-forming polymer.

    Abstract translation: 防腐组合物，以及制备和使用方法，其中所述组合物包括：选自碘（I <下标2>），碘伏剂及其组合的抗微生物剂，其中所述抗微生物剂 药剂的存在量足以提供至少约0.25重量％的可用碘浓度; 羟基羧酸缓冲液，其量为至少约5重量％; 水; 和任选实质的成膜聚合物。

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