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公开(公告)号:US20200179615A1
公开(公告)日:2020-06-11
申请号:US16779135
申请日:2020-01-31
Applicant: AMGEN INC.
Inventor: Lawrence Ring , Dhairya Mehta , Stephanie Toy , Ferry Tamtoro , Alexander Stuart Cairns , Scott R. Gibson
IPC: A61M5/32 , A61M25/00 , A61K38/26 , A61K38/28 , A61K38/19 , C07K14/535 , C12N9/64 , A61M5/142 , A61K9/00 , A61M5/31 , A61M5/14 , A61M5/158 , A61M5/42 , A61M5/20 , A61M25/02
Abstract: A drug delivery device includes a blunt cannula and a reservoir. The blunt cannula has a cylindrical wall that defines an axial passage between a first end and a second end of the blunt cannula. The wall has at least a first tapered region at the first end to define an opening in fluid communication with the axial passage and adapted at the first end to resist interruption of fluid flow through the axial passage and out of the first end of the blunt cannula. The reservoir is connected to the second end of the blunt cannula.
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公开(公告)号:US20150258284A1
公开(公告)日:2015-09-17
申请号:US14434347
申请日:2013-10-18
Applicant: AMGEN, INC.
Inventor: Valerie M. Fenster , Stephanie Toy , Mark Ka Lai Lee , Denise Meyer
CPC classification number: A61M5/425 , A61M5/20 , A61M5/2033 , A61M5/2046 , A61M5/3205 , A61M5/322 , A61M5/326 , A61M5/5086 , A61M2005/206 , A61M2005/2073 , A61M2005/208 , A61M2205/583 , A61M2205/586
Abstract: An injector such as a needle-type autoinjector having a flexible flange disposed at an injection end of the injector for stretching or pinching the skin of the injection site. The flexible flange may be removably attached to the injector or integrated into the injector during manufacturing. Further, an injector having a palm button disposed at an activation end of the injector for activating an injection cycle of the injector. The palm button may be removably attached to the injector or integrated into the injector during manufacturing. Still further, a holding device for one-handed operation of an injector, the holding device having a sleeve and at least one hand rest coupled to the sleeve, the sleeve and hand rest providing ergonomic holding and operation of the injector. Still further, autoinjector needle shield having an enlarged, rounded lip for contacting the skin at the injection site.
Abstract translation: 一种注射器,例如针型自动注射器,其具有设置在注射器的注射端处的柔性凸缘,用于拉伸或夹持注射部位的皮肤。 柔性凸缘可以可拆卸地附接到喷射器或在制造期间集成到喷射器中。 此外,具有手掌按钮的注射器设置在喷射器的激活端,用于启动喷射器的喷射循环。 在制造期间,手掌按钮可以可拆卸地附接到注射器或集成到注射器中。 另外,一种用于单次操作喷射器的保持装置,该保持装置具有一个套筒和至少一个与该套筒相连的扶手,该套筒和手托提供符合人体工程学的保持和操作喷射器。 此外,自动注射器针护罩具有用于在注射部位处接触皮肤的放大的圆形唇缘。
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公开(公告)号:US11511051B2
公开(公告)日:2022-11-29
申请号:US16842468
申请日:2020-04-07
Applicant: AMGEN INC.
Inventor: Mark Ka Lai Lee , Stephanie Toy , Valerie M. Fenster
Abstract: An injector for delivering a therapeutic product may include a base having a flexible surface that conforms to various body contours of a patient and defines one or more an injection chambers. The injector may have a height that is substantially less than its width, thereby defining a low profile, which provides a larger more stable base that can pinch or stretch the skin in a controlled manner. The larger base can also accommodate larger volumes via multiple injection chambers and/or large combined primary containers.
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公开(公告)号:US20220265920A1
公开(公告)日:2022-08-25
申请号:US17735616
申请日:2022-05-03
Applicant: AMGEN INC.
Inventor: Lawrence S. Ring , Dhairya Mehta , Stephanie Toy , Ferry Tamtoro , Alexander Stuart Cairns , Scott R. Gibson
IPC: A61M5/142 , A61M25/02 , A61M5/20 , A61M5/32 , A61M5/42 , A61M25/00 , C12N9/64 , C07K14/535 , A61K38/19 , A61K38/28 , A61K38/26 , A61M5/158 , A61M5/14 , A61M5/31 , A61K9/00
Abstract: A drug delivery device includes a blunt cannula and a reservoir. The blunt cannula has a cylindrical wall that defines an axial passage between a first end and a second end of the blunt cannula. The wall has at least a first tapered region at the first end to define an opening in fluid communication with the axial passage and adapted at the first end to resist interruption of fluid flow through the axial passage and out of the first end of the blunt cannula. The reservoir is connected to the second end of the blunt cannula.
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公开(公告)号:USD796665S1
公开(公告)日:2017-09-05
申请号:US29511176
申请日:2014-12-08
Applicant: AMGEN INC.
Designer: Sahba Tafazoli , Emily Card Razaqi , Valerie M. Fenster , Stephanie Toy , Scott R. Gibson , Denise Meyer , Erik Timpers , Catherine Arboleda Tamura , Peter T. So , Ravi Sawhney , Lance Hussey , Harnish Jani , Kurt Botsai , Young Bang , Gregory VanderPol , Shushuo Wu , Cathy Tran , Noureddine Malaeb
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公开(公告)号:US20160199574A1
公开(公告)日:2016-07-14
申请号:US15040372
申请日:2016-02-10
Applicant: AMGEN INC.
Inventor: Lawrence Ring , Dhairya Mehta , Stephanie Toy , Ferry Tamtoro , Alexander Stuart Cairns , Scott R. Gibson
Abstract: A drug delivery device includes a blunt cannula and a reservoir. The blunt cannula has a cylindrical wall that defines an axial passage between a first end and a second end of the blunt cannula. The wall has at least a first tapered region at the first end to define an opening in fluid communication with the axial passage and adapted at the first end to resist interruption of fluid flow through the axial passage and out of the first end of the blunt cannula. The reservoir is connected to the second end of the blunt cannula
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公开(公告)号:US20160038689A1
公开(公告)日:2016-02-11
申请号:US14776693
申请日:2014-03-14
Applicant: AMGEN INC.
Inventor: Mark Ka Lai Lee , Stephanie Toy , Valerie M. Fenster
CPC classification number: A61M5/3287 , A61M5/19 , A61M5/20 , A61M5/2033 , A61M5/2053 , A61M5/31576 , A61M5/3202 , A61M5/326 , A61M5/425 , A61M5/44 , A61M5/445 , A61M2005/206 , A61M2005/3022 , A61M2005/341
Abstract: An injector for delivering a therapeutic product may include a base having a flexible surface that conforms to various body contours of a patient and defines one or more an injection chambers. The injector may have a height that is substantially less than its width, thereby defining a low profile, which provides a larger more stable base that can pinch or stretch the skin in a controlled manner. The larger base can also accommodate larger volumes via multiple injection chambers and/or large combined primary containers.
Abstract translation: 用于递送治疗产品的注射器可以包括具有符合患者的各种身体轮廓的柔性表面并且限定一个或多个注射室的基部。 注射器可以具有基本上小于其宽度的高度,从而限定低轮廓,其提供更大的更稳定的基部,其可以以受控的方式夹紧或拉伸皮肤。 较大的基座还可以通过多个注射室和/或大的组合的主容器适应较大的体积。
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公开(公告)号:US12115341B2
公开(公告)日:2024-10-15
申请号:US14443847
申请日:2013-11-20
Applicant: AMGEN INC.
Inventor: Lawrence Ring , Dhairya Mehta , Stephanie Toy , Ferry Tamtoro , Alexander Stuart Cairns , Scott R. Gibson
IPC: A61M5/142 , A61K9/00 , A61K38/19 , A61K38/26 , A61K38/28 , A61M5/14 , A61M5/158 , A61M5/20 , A61M5/30 , A61M5/31 , A61M5/32 , A61M5/42 , A61M25/00 , A61M25/02 , C07K14/535 , C12N9/64
CPC classification number: A61M5/14248 , A61K9/0019 , A61K38/193 , A61K38/26 , A61K38/28 , A61M5/14 , A61M5/14216 , A61M5/158 , A61M5/20 , A61M5/3134 , A61M5/3286 , A61M5/3287 , A61M5/3291 , A61M5/422 , A61M25/0015 , A61M25/0068 , A61M25/007 , A61M25/02 , C07K14/535 , C12N9/6424 , A61M2005/1401 , A61M2005/1585 , A61M2005/3022 , A61M2005/3289 , A61M2025/0073 , A61M2202/0007 , A61K38/28 , A61K2300/00 , A61K38/26 , A61K2300/00 , A61K38/193 , A61K2300/00
Abstract: A drug delivery device includes a blunt cannula and a reservoir. The blunt cannula has a cylindrical wall that defines an axial passage between a first end and a second end of the blunt cannula. The wall has at least a first tapered region at the first end to define an opening in fluid communication with the axial passage and adapted at the first end to resist interruption of fluid flow through the axial passage and out of the first end of the blunt cannula. The reservoir is connected to the second end of the blunt cannula.
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公开(公告)号:US10994112B2
公开(公告)日:2021-05-04
申请号:US15039946
申请日:2015-02-03
Applicant: AMGEN INC.
Inventor: Stephanie Toy , Mark Ka Lai Lee , Donald Busby , Melissa D. Norton , Jeffrey Chen
Abstract: A drug delivery device (100) includes a base (102) having a first region (104) with a drug delivery assembly (106) associated therewith. The drug delivery device also includes an antenna (112) disposed in the first region to radiate an electromagnetic field, the base defining a plane (114) and the antenna disposed in the plane of the base, and an electromagnetic field generator (116) selectively coupled to the antenna.
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公开(公告)号:US20180193623A1
公开(公告)日:2018-07-12
申请号:US15039946
申请日:2015-02-03
Applicant: AMGEN INC.
Inventor: Stephanie Toy
IPC: A61M37/00
CPC classification number: A61M37/0015 , A61M37/00 , A61M2037/0007 , A61M2037/0023 , A61M2037/0046 , A61M2037/0061 , A61N1/0412 , A61N1/0428 , A61N1/325
Abstract: A drug delivery device (100) includes a base (102) having a first region (104) with a drug delivery assembly (106) associated therewith. The drug delivery device also includes an antenna (112) disposed in the first region to radiate an electromagnetic field, the base defining a plane (114) and the antenna disposed in the plane of the base, and an electromagnetic field generator (116) selectively coupled to the antenna.
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