公开(公告)号：US11793431B2

公开(公告)日：2023-10-24

申请号：US16959551

申请日：2019-01-11

Applicant: Mayo Foundation for Medical Education and Research ,  Arizona Board of Regents on behalf of Arizona State University

Inventor： Marylaura Thomas ,  Leslie Thomas ,  Erica Forzani

IPC: A61B5/1455 ,  A61B5/145 ,  A61B5/20 ,  A61B5/00 ,  B01D53/22

CPC classification number: A61B5/14552 ,  A61B5/14546 ,  A61B5/201 ,  A61B5/4866 ,  B01D53/228 ,  B01D2259/10

Abstract: A system with an analyzer device in fluid communication with a sample of a bodily fluid is configured to chemically or electrochemically convert at least a portion of ammonium (NH4+) contained within the bodily fluid into ammonia (NH3) and dispel the converted ammonia (NH3) into a gas sensing chamber. An ammonia (NH3) sensor located within the gas sensing chamber in conjunction with a processor can quantify an amount of ammonia (NH3) present in the gas sensing chamber in relation to the total ammonia of the bodily fluid.

公开(公告)号：US20190257802A1

公开(公告)日：2019-08-22

申请号：US16279698

申请日：2019-02-19

Applicant: Arizona Board of Regents on behalf of Arizona State University

Inventor： Erica Forzani ,  Nongjian Tao ,  Di Zhao ,  Francis Tsow

IPC: G01N33/00 ,  A61B5/00 ,  G01N21/84 ,  A61B5/08 ,  G01N33/497

Abstract: A method for CO2 detection includes obtaining a gas sample; exposing a CO2 sensor to the gas sample, where the sensor includes a reversible and selective pH-sensitive nanocomposite sensor element for CO2 detection, and a hydrophobic surface; compensating for humidity and temperature; coupling at least one light source to receive signals from the CO2 sensor and respond to color changes in the sensor by transducing the color change into a light intensity change; measuring flow; and receiving signals from the at least one light source by at least one photodiode which responds to light intensity changes by transducing the light intensity changes into electronic signals representing varying degrees of light intensity.

公开(公告)号：US20210076999A1

公开(公告)日：2021-03-18

申请号：US16959551

申请日：2019-01-11

Applicant: Mayo Foundation for Medical Education and Research ,  Arizona Board of Regents on behalf of Arizona State University

Inventor： Marylaura Thomas ,  Leslie Thomas ,  Erica Forzani

IPC: A61B5/1455 ,  A61B5/145 ,  A61B5/20 ,  A61B5/00 ,  B01D53/22 ,  G01N21/77 ,  G01N33/487

Abstract: A system with an analyzer device in fluid communication with a sample of a bodily fluid is configured to chemically or electrochemically convert at least a portion of ammonium (NH4+) contained within the bodily fluid into ammonia (NH3) and dispel the converted ammonia (NH3) into a gas sensing chamber. An ammonia (NH3) sensor located within the gas sensing chamber in conjunction with a processor can quantify an amount of ammonia (NH3) present in the gas sensing chamber in relation to the total ammonia of the bodily fluid.

公开(公告)号：US20240335146A1

公开(公告)日：2024-10-10

申请号：US18736041

申请日：2024-06-06

Applicant: Mayo Foundation for Medical Education and Research ,  Arizona Board of Regents on behalf of Arizona State University

Inventor： Marylaura Thomas ,  Leslie Thomas ,  Erica Forzani

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/145 ,  A61B5/20 ,  B01D53/22

CPC classification number: A61B5/14552 ,  A61B5/14546 ,  A61B5/201 ,  A61B5/4866 ,  B01D53/228 ,  B01D2259/10

Abstract: A system with an analyzer device in fluid communication with a sample of a bodily fluid is configured to chemically or electrochemically convert at least a portion of ammonium (NH4+) contained within the bodily fluid into ammonia (NH3) and dispel the converted ammonia (NH3) into a gas sensing chamber. An ammonia (NH3) sensor located within the gas sensing chamber in conjunction with a processor can quantify an amount of ammonia (NH3) present in the gas sensing chamber in relation to the total ammonia of the bodily fluid.

公开(公告)号：US11566801B2

公开(公告)日：2023-01-31

申请号：US16959646

申请日：2019-01-02

Applicant: Arizona Board of Regents on behalf of Arizona State University

Inventor： Erica Forzani ,  Nongjian Tao ,  Francis Tsow

IPC: F24F11/00 ,  F24F11/63 ,  F24F11/77 ,  F24F110/10 ,  F24F110/70 ,  F24F120/10 ,  F24F11/30 ,  F24F11/74

Abstract: An integrated method for assessing metabolic rate and maintaining indoor air quality and efficient ventilation energy use. A physical sensor assesses room occupancy. An actuated ventilation system is set to a constant CO2 level in a predetermined healthy range, where the actuated ventilation system includes a CO2 sensor. The actuated ventilation system sets a first air ventilation rate and the sensor measures a first CO2 level. The system determines whether CO2 level is in a healthy range, if not then the CO2 level is adjusted by setting a subsequent air ventilation rate. A subsequent CO2 level is measured. If the CO2 level is determined to meet a predetermined healthy range, then an assessment of change of air ventilation rate (Δ ACH) is determined. The determination of air change rate can be further augmented by a physical pressure based measurement. The overall metabolic rate is generated.

公开(公告)号：US09931055B2

公开(公告)日：2018-04-03

申请号：US14431730

申请日：2013-09-27

Applicant: Arizona Board of Regents on behalf of Arizona State University

Inventor： Erica Forzani ,  Nongjian Tao ,  Xiaojun Xian ,  Francis Tsow

IPC: A61B5/08 ,  A61B5/097 ,  A61B5/087 ,  G01N33/497

CPC classification number: A61B5/082 ,  A61B5/087 ,  A61B5/097 ,  G01N33/497

Abstract: A low back pressure mouthpiece for accurate detection of exhaled nitric oxide (NO) includes a conduit for receiving the exhaled breath from the subject. An oxidizing filter for sample conditioning, wherein the conduit and oxidizing filter operate to produce a back pressure of less than 4 cm H2O; and a device for measuring the level of one or more components of the received exhaled breath.

公开(公告)号：US20230330379A1

公开(公告)日：2023-10-19

申请号：US18043525

申请日：2021-09-01

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY ,  MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH

Inventor： Erica Forzani ,  Xiaojun Xian ,  Bhavesh Patel ,  Kelly McKay

IPC: A61M16/10 ,  A61M16/06

CPC classification number: A61M16/1065 ,  A61M16/0683 ,  A61M16/0666 ,  A61M16/0616 ,  A61M16/1055 ,  A61M2205/7509 ,  A61M2205/7518

Abstract: An apparatus and method for mitigating release of aerosols from a nebulizer treatment device, or from the respiratory system of a contaminated subject utilizes a mask configured to cover the nose and mouth of the subject, and utilizes a high efficiency filter and fan coupled with an exhaust port of the mask. The fan creates a pressure differential that causes the respiratory products to flow through the high efficiency filter, where aerosols are captured. The mask may further include at least one inlet port for admission of gas (e.g., oxygen) or aerosols. The apparatus provides adequate inhaled oxygen levels and avoids carbon dioxide rebreathing problems.

公开(公告)号：US20230329596A1

公开(公告)日：2023-10-19

申请号：US18212358

申请日：2023-06-21

Applicant: Mayo Foundation for Medical Education and Research ,  Arizona Board of Regents on behalf of Arizona State University

Inventor： Marylaura Thomas ,  Leslie Thomas ,  Erica Forzani

IPC: A61B5/1455 ,  A61B5/145 ,  A61B5/20 ,  A61B5/00 ,  B01D53/22

CPC classification number: A61B5/14552 ,  A61B5/14546 ,  A61B5/201 ,  A61B5/4866 ,  B01D53/228 ,  B01D2259/10

Abstract: A system with an analyzer device in fluid communication with a sample of a bodily fluid is configured to chemically or electrochemically convert at least a portion of ammonium (NH4−) contained within the bodily fluid into ammonia (NH3) and dispel the converted ammonia (NH3) into a gas sensing chamber. An ammonia (NH3) sensor located within the gas sensing chamber in conjunction with a processor can quantify an amount of ammonia (NH3) present in the gas sensing chamber in relation to the total ammonia of the bodily fluid.

公开(公告)号：US10663442B2

公开(公告)日：2020-05-26

申请号：US16279698

申请日：2019-02-19

Applicant: Arizona Board of Regents on behalf of Arizona State University

Inventor： Erica Forzani ,  Nongjian Tao ,  Di Zhao ,  Francis Tsow

IPC: G01N31/00 ,  G01N33/00 ,  A61B5/08 ,  G01N21/84 ,  G01N33/497 ,  A61B5/00 ,  G01N1/22

Abstract: A method for CO2 detection includes obtaining a gas sample; exposing a CO2 sensor to the gas sample, where the sensor includes a reversible and selective pH-sensitive nanocomposite sensor element for CO2 detection, and a hydrophobic surface; compensating for humidity and temperature; coupling at least one light source to receive signals from the CO2 sensor and respond to color changes in the sensor by transducing the color change into a light intensity change; measuring flow; and receiving signals from the at least one light source by at least one photodiode which responds to light intensity changes by transducing the light intensity changes into electronic signals representing varying degrees of light intensity.

公开(公告)号：US12178575B2

公开(公告)日：2024-12-31

申请号：US18212358

申请日：2023-06-21

Applicant: Mayo Foundation for Medical Education and Research ,  Arizona Board of Regents on behalf of Arizona State University

Inventor： Marylaura Thomas ,  Leslie Thomas ,  Erica Forzani

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/145 ,  A61B5/20 ,  B01D53/22

Abstract: A system with an analyzer device in fluid communication with a sample of a bodily fluid is configured to chemically or electrochemically convert at least a portion of ammonium (NH4+) contained within the bodily fluid into ammonia (NH3) and dispel the converted ammonia (NH3) into a gas sensing chamber. An ammonia (NH3) sensor located within the gas sensing chamber in conjunction with a processor can quantify an amount of ammonia (NH3) present in the gas sensing chamber in relation to the total ammonia of the bodily fluid.