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    Systems and methods for acquiring making time-sequential measurements of biopotentials sensed in myocardial tissue
    6.
    发明授权
    Systems and methods for acquiring making time-sequential measurements of biopotentials sensed in myocardial tissue 有权
    用于获取在心肌组织中感测的生物电位的时间顺序测量的系统和方法

    公开(公告)号：US06188924B1

    公开(公告)日：2001-02-13

    申请号：US09247442

    申请日：1999-02-10

    申请人： David K. Swanson ,  James G. Whayne ,  Dorin Panescu

    发明人： David K. Swanson ,  James G. Whayne ,  Dorin Panescu

    IPC分类号： A61B50402

    CPC分类号： A61B5/6855 ,  A61B1/0051 ,  A61B5/0422 ,  A61B5/04525 ,  A61B5/6858 ,  A61B18/1492 ,  A61N1/056 ,  G06F19/00 ,  G16H15/00 ,  G16H40/63

    摘要： Systems and methods for generating a composite signal derived from biopotentials sensed in myocardial tissue are disclosed and described. One such method includes inputting a first set of signals comprising biopotentials sensed at a first group of tissue sites during a first time interval; inputting a second set of signals comprising biopotentials sensed at a second group of tissue sites during a second time interval sequentially after the first time interval, wherein at least one of the biopotentials sensed as part of the first set of signals is not sensed as part of the second set of signals, and at least one of the biopotentials sensed as part of the second set of signals is not sensed as part of the first set of signals; and time aligning the first and second sets of signals using biopotentials sensed at the same site as part of both the first and second sets of signals, thereby generating the composite signal arranged for analysis as if all biopotentials were sensed during a common time interval, whereby the composite signal provides a diagnostic indicator.

    摘要翻译： 公开和描述了用于产生从心肌组织中感测的生物电位得到的复合信号的系统和方法。 一种这样的方法包括在第一时间间隔期间输入包括在第一组组织位点处感测的生物电位的第一组信号; 在所述第一时间间隔之后，在第二时间间隔期间输入包括在第二组组织位置处感测的生物电位的第二组信号，其中作为所述第一组信号的一部分感测到的所述生物电位中的至少一个未被感测为 所述第二组信号以及作为所述第二组信号的一部分感测到的所述生物电位中的至少一个未被感测为所述第一组信号的一部分; 以及使用在同一位点处感测的生物电位作为第一组信号和第二组信号的一部分的时间对齐第一组信号和第二组信号，从而生成布置成用于分析的复合信号，好像在公共时间间隔期间感测到所有生物电位一样，由此 复合信号提供诊断指示器。

    Systems and methods employing structures having asymmetric mechanical properties to support diagnostic or therapeutic elements in contact with tissue in interior body regions
    9.
    发明授权
    Systems and methods employing structures having asymmetric mechanical properties to support diagnostic or therapeutic elements in contact with tissue in interior body regions 失效
    使用具有不对称机械性能的结构以支持与内部身体区域中的组织接触的诊断或治疗元件的系统和方法

    公开(公告)号：US6014590A

    公开(公告)日：2000-01-11

    申请号：US742564

    申请日：1996-10-28

    申请人： James G. Whayne ,  Sidney D. Fleischman ,  Dorin Panescu ,  Thomas F. Kordis ,  David K. Swanson

    发明人： James G. Whayne ,  Sidney D. Fleischman ,  Dorin Panescu ,  Thomas F. Kordis ,  David K. Swanson

    IPC分类号： A61B17/39

    摘要： Structures having asymmetric mechanical properties provide enhanced ability to support therapeutic or diagnostic elements in contact with tissue in an interior body region. The support structure includes a first region, which exhibits a first mechanical property affecting tissue contact, and a second region spaced from the first region about the axis, which exhibits a second mechanical property, different than the first mechanical property, affecting tissue contact. In a preferred embodiment, the first and second mechanical properties correlate with stiffness of the respective first and second regions, with the first region being more flexible (i.e., less stiff) than the second region. The first region, due to its greater flexibility, is more conformal to tissue than the second region. The less flexible (i.e., more stiff) second region imparts greater force against the tissue to urge the more flexible first region toward intimate tissue contact. In a preferred embodiment, the more flexible first region carries at least one therapeutic or diagnostic element.

    摘要翻译： 具有不对称机械特性的结构提供增强的能力，以支持与内部身体区域中的组织接触的治疗或诊断元件。 支撑结构包括表现出影响组织接触的第一机械特性的第一区域以及围绕轴线与第一区域隔开的第二区域，该第二区域具有影响组织接触的第二机械特性，该第二机械特性不同于第一机械特性。 在优选实施例中，第一和第二机械特性与相应的第一和第二区域的刚度相关，其中第一区域比第二区域更加柔性（即，较不硬）。 第一个区域由于其更大的灵活性，比第二个区域更适合组织。 较不柔性（即更硬）的第二区域赋予组织更大的力以促使更柔性的第一区域朝向紧密的组织接触。 在优选实施方案中，更灵活的第一区域携带至少一种治疗或诊断元件。