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公开(公告)号：US20170305900A1
公开(公告)日：2017-10-26
申请号：US15482327
申请日：2017-04-07
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , Ignacio Muñoz-Sanjuán , Michel Maillard , Christopher A. Luckhurst , Rebecca E. Jarvis , Roland W. Bürli , Daniel R. Allen , Alan F. Haughan , Perla Breccia , Huw D. Vater , Andrew J. Stott , Stephen D. Penrose , Michael Wall , Elizabeth A. Saville-Stones , Grant Wishart , Samantha J. Hughes
IPC: C07D471/04 , C07D277/64 , C07C259/08 , C07D277/62 , C07D275/04 , C07D261/20 , C07D241/42 , C07D241/12 , C07D239/26 , C07D231/56 , C07D231/12 , C07D213/64 , C07D213/61 , C07D213/56 , C07D333/60 , C07C2601/02 , C07C2601/10
CPC classification number: C07D471/04 , C07C259/08 , C07C2601/02 , C07C2601/10 , C07D213/56 , C07D213/61 , C07D213/64 , C07D231/12 , C07D231/56 , C07D239/26 , C07D241/12 , C07D241/42 , C07D261/20 , C07D275/04 , C07D277/62 , C07D277/64 , C07D333/60
Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
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公开(公告)号：US09783488B2
公开(公告)日：2017-10-10
申请号：US14776280
申请日：2014-03-10
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , Ignacio Muñoz-Sanjuán , Michel Maillard , Gilles Raphy , Alan F. Haughan , Christopher A. Luckhurst , Rebecca E. Jarvis , Roland W. Bürli , Perla Breccia , Grant Wishart , Samantha J. Hughes , Daniel R. Allen , Stephen D. Penrose
IPC: A61K31/133 , C07C233/60 , C07D263/56 , C07D215/14 , C07D231/12 , C07D231/56 , C07D333/54 , C07D235/08 , C07D239/26 , C07D471/04 , C07D265/36 , C07D277/64 , C07D295/073 , C07D213/54 , C07D213/56 , C07D307/79 , C07C259/08 , C07D209/46 , C07D213/58 , C07D215/06 , C07D235/06 , C07D263/57 , C07D265/30 , C07D277/66 , C07D307/81 , C07D311/96 , C07D401/12 , C07D413/06
CPC classification number: C07C233/60 , C07C259/08 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07D209/46 , C07D213/54 , C07D213/56 , C07D213/58 , C07D215/06 , C07D215/14 , C07D231/12 , C07D231/56 , C07D235/06 , C07D235/08 , C07D239/26 , C07D263/56 , C07D263/57 , C07D265/30 , C07D265/36 , C07D277/64 , C07D277/66 , C07D295/073 , C07D307/79 , C07D307/81 , C07D311/96 , C07D333/54 , C07D401/12 , C07D413/06 , C07D471/04
Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
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公开(公告)号：US20160031876A1
公开(公告)日：2016-02-04
申请号：US14776320
申请日：2014-03-10
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , Ignacio Muñoz-Sanjuán , Michel Maillard , Christopher A. Luckhurst , Rebecca E. Jarvis , Roland W. Bürli , Daniel R. Allen , Alan F. Haughan , Perla Breccia , Huw D. Vater , Andrew J. Stott , Stephen D. Penrose , Michael Wall , Elizabeth A. Saville-Stones , Grant Wishart , Samantha J. Hughes
IPC: C07D471/04 , C07D213/56 , C07D241/12 , C07D239/26 , C07D213/61 , C07D333/60 , C07D231/12 , C07D261/20 , C07D213/64 , C07D275/04 , C07D277/64 , C07C259/08 , C07D241/42
CPC classification number: C07D471/04 , C07C259/08 , C07C2601/02 , C07C2601/10 , C07D213/56 , C07D213/61 , C07D213/64 , C07D231/12 , C07D231/56 , C07D239/26 , C07D241/12 , C07D241/42 , C07D261/20 , C07D275/04 , C07D277/62 , C07D277/64 , C07D333/60
Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
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Patent Agency Ranking
公开(公告)号：US20240199624A1
公开(公告)日：2024-06-20
申请号：US18521696
申请日：2023-11-28
Applicant: CHDI Foundation, Inc.
Inventor： Tasir Haque , Michel Maillard , Gareth Brace , George Ballantyne , Elizabeth Frush , Kim Hirst , Katherine Jones , Emanuela Gancia , Chris Lock , Cole Clissold
CPC classification number: C07D487/04 , A61K9/02 , A61K9/2013 , A61K9/2018 , A61K9/2054 , A61K9/2059 , A61K9/4858 , A61K47/12 , A61K47/14 , A61K47/26
Abstract: The present disclosure relates generally to small molecule inhibitors of MutSβ protein, or a pharmaceutically acceptable salt, isotopically enriched analog, stereoisomer, mixture of stereoisomers, or prodrug thereof, methods of making and intermediates thereof, and methods of using thereof.
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公开(公告)号：US10106535B2
公开(公告)日：2018-10-23
申请号：US15482327
申请日：2017-04-07
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , Ignacio Muñoz-Sanjuán , Michel Maillard , Christopher A. Luckhurst , Rebecca E. Jarvis , Roland W. Bürli , Daniel R. Allen , Alan F. Haughan , Perla Breccia , Huw D. Vater , Andrew J. Stott , Stephen D. Penrose , Michael Wall , Elizabeth A. Saville-Stones , Grant Wishart , Samantha J. Hughes
IPC: C07D471/04 , C07C259/08 , C07D277/64 , C07D231/12 , C07D231/56 , C07D261/20 , C07D241/12 , C07D239/26 , C07D213/61 , C07D333/60 , C07D275/04 , C07D213/64 , C07D277/62 , C07D241/42 , C07D213/56
Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
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公开(公告)号：US20160039745A1
公开(公告)日：2016-02-11
申请号：US14776280
申请日：2014-03-10
Applicant: CHDI FOUNDATION, INC.
Inventor： Celia Dominguez , Ignacio Muñoz-San Juan , Michel Maillard , Gilles Raphy , Alan F. Haughan , Christopher A. Luckhurst , Rebecca E. Jarvis , Roland W. Burli , Grant Wishart , Samantha J. Hughes , Daniel R. Allen , Stephen D. Penrose , Perla Breccia
IPC: C07C233/60 , C07D413/06 , C07D239/26 , C07D471/04 , C07D401/12 , C07D213/58 , C07D231/12 , C07D209/46 , C07D307/81 , C07D235/06 , C07D277/66 , C07D215/06 , C07D311/96 , C07D263/57 , C07D231/56 , C07D265/30 , C07D265/36
CPC classification number: C07C233/60 , C07C259/08 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07D209/46 , C07D213/54 , C07D213/56 , C07D213/58 , C07D215/06 , C07D215/14 , C07D231/12 , C07D231/56 , C07D235/06 , C07D235/08 , C07D239/26 , C07D263/56 , C07D263/57 , C07D265/30 , C07D265/36 , C07D277/64 , C07D277/66 , C07D295/073 , C07D307/79 , C07D307/81 , C07D311/96 , C07D333/54 , C07D401/12 , C07D413/06 , C07D471/04
Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
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公开(公告)号：US20160031863A1
公开(公告)日：2016-02-04
申请号：US14776058
申请日：2014-03-10
Applicant: CHDI FOUNDATION, INC.
Inventor： Celia Dominguez , Ignacio Muñoz-Sanjuán , Michel Maillard , Huw D. Vater , Rebecca E. Jarvis , Christopher A. Luckhurst , Roland W. Bürli , Grant Wishart , Andrew J. Stott
IPC: C07D409/04 , C07D207/34 , C07D231/14 , C07D401/04 , C07D403/04
CPC classification number: C07D409/04 , C07D207/34 , C07D231/14 , C07D231/22 , C07D401/04 , C07D403/04
Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
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公开(公告)号：US09617259B2
公开(公告)日：2017-04-11
申请号：US14776320
申请日：2014-03-10
Applicant: CHDI Foundation, Inc.
Inventor： Celia Dominguez , Ignacio Muñoz-Sanjuán , Michel Maillard , Christopher A. Luckhurst , Rebecca E. Jarvis , Roland W. Bürli , Daniel R. Allen , Alan F. Haughan , Perla Breccia , Huw D. Vater , Andrew J. Stott , Stephen D. Penrose , Michael Wall , Elizabeth A. Saville-Stones , Grant Wishart , Samantha J. Hughes
IPC: C07D471/04 , C07D277/64 , C07D241/12 , C07D213/64 , C07C259/08 , C07D277/62 , C07D261/20 , C07D275/04 , C07D333/60 , C07D213/56 , C07D213/61 , C07D239/26 , C07D241/42 , C07D231/12 , C07D231/56
CPC classification number: C07D471/04 , C07C259/08 , C07C2601/02 , C07C2601/10 , C07D213/56 , C07D213/61 , C07D213/64 , C07D231/12 , C07D231/56 , C07D239/26 , C07D241/12 , C07D241/42 , C07D261/20 , C07D275/04 , C07D277/62 , C07D277/64 , C07D333/60
Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
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