-
公开(公告)号：US20150275167A1
公开(公告)日：2015-10-01
申请号：US14663533
申请日：2015-03-20
Applicant: Corning Incorporated
Inventor： Ronald Allen Faris , Ann MeeJin Ferrie , Vasiliy Nikolaevich Goral , Gregory Roger Martin , Jin Liu
CPC classification number: A61K9/2866
Abstract: An ex vivo cell culture sustained release composition, including: a mixture comprising: a sustenant; and a non-biodegradable binder; and a non-biodegradable and water insoluble encapsulant coat that encapsulates the mixture, as defined herein. Also disclosed is a method for sustainably providing a sustenant to a cell culture in aqueous media, including contacting a cell culture with the sustained release composition.
Abstract translation: 一种离体细胞培养持续释放组合物，包括：包含：维生素的混合物; 和不可生物降解的粘合剂; 以及包封如本文所定义的混合物的不可生物降解的水不溶性包封剂涂层。 还公开了一种用于将水分介质中的细胞培养物可持续地提供给细胞培养物的方法，包括使细胞培养物与持续释放组合物接触。
-
公开(公告)号：US20240099307A1
公开(公告)日：2024-03-28
申请号：US18275739
申请日：2022-02-04
Applicant: CORNING INCORPORATED
Inventor： Bavani Balakrisnan , Charles Brandenburg , Douglas Edmon Goforth , Cassandra Ann Haynes , Insik Jeon , Jenny Kim , Joydeep Lahiri , Jin Liu , Kevin Robert McCarthy , Michael Lesley Sorensen
IPC: A01N59/20 , A01N25/10 , A01P1/00 , C09D5/14 , C09D175/04 , C09D183/04
CPC classification number: A01N59/20 , A01N25/10 , A01P1/00 , C09D5/14 , C09D175/04 , C09D183/04
Abstract: A method for making an antimicrobial composite film can include forming a first coating layer by applying a first coating material on a substrate and forming a second coating layer by applying a second coating material on the first coating layer. The first coating material can comprise a first resin. The second coating material can comprise an antimicrobial material in a second resin or a dispersion. The first coating material can have a lower concentration of the antimicrobial material than the second coating material. The first and second coating layers can cooperatively define a composite film. The antimicrobial material can be asymmetrically dispersed in the composite film such that the antimicrobial material is concentrated closer to the outer surface of the composite film than to the inner surface of the composite film.
-
公开(公告)号：US20220062186A1
公开(公告)日：2022-03-03
申请号：US17501325
申请日：2021-10-14
Applicant: CORNING INCORPORATED
Inventor： Ronald Allen Faris , Ann MeeJin Ferrie , Vasiliy Nikolaevich Goral , Jin Liu , Gregory Roger Martin
IPC: A61K9/28
Abstract: An ex vivo cell culture sustained release composition, including: a mixture comprising: a sustenant; and a non-biodegradable binder; and a non-biodegradable and water insoluble encapsulant coat that encapsulates the mixture, as defined herein. Also disclosed is a method for sustainably providing a sustenant to a cell culture in aqueous media, including contacting a cell culture with the sustained release composition.
-
公开(公告)号：US20150291932A1
公开(公告)日：2015-10-15
申请号：US14647304
申请日：2013-11-25
Applicant: Ronald Allen FARIS , Yulong HONG , Joydeep LAHIRI , Jin LIU , Olivia Grace WEEKS , CORNING INCORPORATED
Inventor： Ronald Allen Faris , Yulong Hong , Joydeep Lahiri , Jin Liu , Olivia Grace Weeks
CPC classification number: C12N5/067 , C12N2501/727 , C12N2501/999 , C12N2503/02 , C12N2506/02 , C12N2533/54 , C12Q1/6876 , C12Q2600/158 , G01N33/5067 , G01N2333/90245
Abstract: Cell culture compositions containing LFM-A13 or a structurally related compound can enhance global hepatic function. For example, LFM-A13 is shown to enhance levels of a broad variety of drug metabolism enzymes, including CYP enzymes, and other hepatic enzymes. LFM-A13 is also shown to promote differentiation of stem cells into hepatocytes. LFM-A13 and structurally related compounds can be used in cell culture to enhance global drug metabolism of liver cells for enhanced in vitro study the effects of drug metabolism on other candidate drug compounds.
Abstract translation: 含有LFM-A13或结构相关化合物的细胞培养组合物可以增强全身肝功能。 例如，LFM-A13被证明可以增强多种药物代谢酶的水平，包括CYP酶和其他肝酶。 还显示LFM-A13促进干细胞分化成肝细胞。 LFM-A13和结构相关的化合物可用于细胞培养，以增强肝细胞的全球药物代谢，增强体外研究药物代谢对其他候选药物化合物的作用。
-
-
-
Search Results
4
records
(took 0.012 seconds)
