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公开(公告)号：US07676960B2
公开(公告)日：2010-03-16
申请号：US11732935
申请日：2007-04-05
IPC分类号： A43B5/00
CPC分类号： A61B5/1036 , A43B1/0054 , A43B3/00 , A43B3/0005 , A43B3/0042 , A43B5/06 , A43B13/181 , A43B13/187 , A43B21/26
摘要： The invention is directed to intelligent systems for articles of footwear that adjust automatically in response to a measured performance characteristic. The intelligent systems include one or more adjustable elements coupled to a mechanism that actuates the adjustable elements in response to a signal from a sensor to modify the performance characteristic of the article of footwear. The intelligent system adjusts the performance characteristics of the article of footwear without human intervention.
摘要翻译： 本发明涉及针对鞋类物品的智能系统，该智能系统响应于测量的性能特性自动调整。 智能系统包括耦合到机构的一个或多个可调节元件，该机构响应于来自传感器的信号来致动可调节元件，以改变鞋类物品的性能特征。 智能系统调整鞋类的性能特征，无需人为干预。
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公开(公告)号：US07188439B2
公开(公告)日：2007-03-13
申请号：US10385300
申请日：2003-03-10
IPC分类号： A43B5/00
CPC分类号： A61B5/1036 , A43B1/0054 , A43B3/00 , A43B3/0005 , A43B3/0042 , A43B5/06 , A43B13/181 , A43B13/187 , A43B21/26
摘要： The invention is directed to intelligent systems for articles of footwear that adjust automatically in response to a measured performance characteristic. The intelligent systems include one or more adjustable elements coupled to a mechanism that actuates the adjustable elements in response to a signal from a sensor to modify the performance characteristic of the article of footwear. The intelligent system adjusts the performance characteristics of the article of footwear without human intervention.
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公开(公告)号：US07506460B2
公开(公告)日：2009-03-24
申请号：US11522727
申请日：2006-09-18
IPC分类号： A43B5/04
CPC分类号： A61B5/1036 , A43B1/0054 , A43B3/00 , A43B3/0005 , A43B3/0042 , A43B5/06 , A43B13/181 , A43B13/187 , A43B21/26
摘要： The invention is directed to intelligent systems for articles of footwear that adjust automatically in response to a measured performance characteristic. The intelligent systems include one or more adjustable elements coupled to a mechanism that actuates the adjustable elements in response to a signal from a sensor to modify the performance characteristic of the article of footwear. The intelligent system adjusts the performance characteristics of the article of footwear without human intervention.
摘要翻译： 本发明涉及针对鞋类物品的智能系统，该智能系统响应于测量的性能特性自动调整。 智能系统包括耦合到机构的一个或多个可调节元件，该机构响应于来自传感器的信号来致动可调节元件，以改变鞋类物品的性能特征。 智能系统调整鞋类的性能特征，无需人为干预。
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公开(公告)号：US20070180736A1
公开(公告)日：2007-08-09
申请号：US11732935
申请日：2007-04-05
IPC分类号： A43B5/00
CPC分类号： A61B5/1036 , A43B1/0054 , A43B3/00 , A43B3/0005 , A43B3/0042 , A43B5/06 , A43B13/181 , A43B13/187 , A43B21/26
摘要： The invention is directed to intelligent systems for articles of footwear that adjust automatically in response to a measured performance characteristic. The intelligent systems include one or more adjustable elements coupled to a mechanism that actuates the adjustable elements in response to a signal from a sensor to modify the performance characteristic of the article of footwear. The intelligent system adjusts the performance characteristics of the article of footwear without human intervention.
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公开(公告)号：US20070011920A1
公开(公告)日：2007-01-18
申请号：US11522727
申请日：2006-09-18
IPC分类号： A43B5/00
CPC分类号： A61B5/1036 , A43B1/0054 , A43B3/00 , A43B3/0005 , A43B3/0042 , A43B5/06 , A43B13/181 , A43B13/187 , A43B21/26
摘要： The invention is directed to intelligent systems for articles of footwear that adjust automatically in response to a measured performance characteristic. The intelligent systems include one or more adjustable elements coupled to a mechanism that actuates the adjustable elements in response to a signal from a sensor to modify the performance characteristic of the article of footwear. The intelligent system adjusts the performance characteristics of the article of footwear without human intervention.
摘要翻译： 本发明涉及针对鞋类物品的智能系统，该智能系统响应于测量的性能特性自动调整。 智能系统包括耦合到机构的一个或多个可调节元件，该机构响应于来自传感器的信号来致动可调节元件，以改变鞋类物品的性能特征。 智能系统调整鞋类的性能特征，无需人为干预。
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6.发明申请PURIFIED POLYPEPTIDE COMPRISING OR CONSISTING OF A C-TERMINUS MSP1 ANTIGEN FROM PLASMODIUM FALCIPARUM CARRYING A GLYCOSYL-PHOSPHATIDYL-INOSITOL GROUP (GPI) 失效包含或包含来自携带糖蛋白 - 磷脂酰胺基团（GPI）的丙酸纤维素的C-TERMINUS MSP1抗原的纯化多肽公开(公告)号：US20100255038A1
公开(公告)日：2010-10-07
申请号：US11622845
申请日：2007-01-12
IPC分类号： A61K39/015 , C07H21/04 , C07K14/445 , C07K7/00 , A61P31/12 , C12N15/63 , C12N7/01
CPC分类号： A61K39/015 , A01K2227/101 , A01K2267/02 , A61K39/00 , C07K14/445 , C07K16/205 , C12N2799/026 , Y02A50/412
摘要： The present invention relates to a purified polypeptide comprising or consisting of a C-terminus MSP1 antigen from Plasmodium falciparum carrying a Glycosyl-phosphatidyl-inositol group (GPI), an immunogenic composition and a vaccine against a Plasmodium infection comprising said purified polypeptide.
摘要翻译： 本发明涉及包含携带糖基 - 磷脂酰肌醇基团（GPI）的恶性疟原虫的C末端MSP1抗原或免疫原性组合物和针对包含所述纯化多肽的疟原虫感染疫苗的纯化多肽。
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7.发明申请公开(公告)号：US20060135094A1
公开(公告)日：2006-06-22
申请号：US11014805
申请日：2004-12-20
申请人： Amit Dor , Charles Roth , Mark Fullerton
发明人： Amit Dor , Charles Roth , Mark Fullerton
IPC分类号： H01Q11/12
CPC分类号： G06F1/206 , G06F1/3203 , G06F1/324 , G06F1/3296 , Y02D10/126 , Y02D10/16 , Y02D10/172
摘要： Briefly, a method an apparatus of a power management system of a semiconductor device capable of managing a power consumption of the semiconductor device by varying an operating voltage of the semiconductor device according to a voltage value based on a reference number.
摘要翻译： 简而言之，是一种能够通过基于参考数根据电压值改变半导体器件的工作电压来管理半导体器件的功耗的半导体器件的电源管理系统的装置的方法。
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公开(公告)号：US10286088B2
公开(公告)日：2019-05-14
申请号：US14115752
申请日：2012-05-07
IPC分类号： A61K49/00
摘要： Disclosed is a method of non-invasive infrared imaging, comprising (a) administering a composition containing infrared-emitting particles which contain rare earth elements that emit in the short-wavelength infrared (SWIR) spectrum, where the particles are encapsulated with a biocompatible matrix to form downconverting encapsulated particles; and (b) irradiating with infrared radiation, where both excitation and emission spectra of the encapsulated particles are in the infrared region. Analogous methods of image-guided biomedical intervention, and drug tracking and delivery are also disclosed. Also disclosed is a composition for biomedical applications, containing infrared-emitting particles which contain rare earth-elements that emit in the short-wavelength infrared (SWIR) spectrum, where the particles are encapsulated with a biocompatible matrix to form downconverting encapsulated particles.
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9.发明授权公开(公告)号：US08962757B2
公开(公告)日：2015-02-24
申请号：US12744824
申请日：2008-11-26
申请人： David I. Devore , Charles Roth
发明人： David I. Devore , Charles Roth
CPC分类号： C08F265/02 , A61K31/70 , A61K47/32 , C08G81/025
摘要： Innovative graft polymers designed for the efficient delivery of antisense molecules into biological cells and for maintaining the biological activity of these molecules while in serum and other aqueous environments are provided. Such polymers may comprise an anionic graft polymer comprising an anionic polymer backbone with pendant carboxylic acid groups and pendant chains comprising amphipathic or hydrophilic polymers covalently bonded to a portion of said pendant carboxylic acid groups. Antisense molecule delivery vectors comprising such polymers in combination with cationic agents for delivery of antisense molecules are also disclosed.
摘要翻译： 提供了设计用于将反义分子有效递送到生物细胞中并用于在血清和其它水性环境中维持这些分子的生物学活性的创新的接枝聚合物。 这样的聚合物可以包含阴离子接枝聚合物，其包含具有侧挂羧酸基团的阴离子聚合物主链和包含共价键合到所述侧挂羧酸基团的一部分的两亲性或亲水性聚合物的侧链。 还公开了包含这种聚合物与用于递送反义分子的阳离子试剂组合的反义分子递送载体。
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10.发明授权公开(公告)号：US07696308B2
公开(公告)日：2010-04-13
申请号：US11144833
申请日：2005-06-06
CPC分类号： A61K39/015 , A61K39/00 , C07K14/445 , C07K16/205 , C12N2799/026 , Y02A50/412
摘要： The invention relates to a recombinant protein fabricated in a baculovirus system, of which the essential constitutive polypeptide sequence is that of a C-terminal fragment of 19 kilodalton (p19) of the surface protein 1 (protein MSP-1) of the merozoite parasite of the Plasmodium type, particularly Plasmodium falciparum, which is infectious for humans, said C-terminal fragment remaining normally anchored at the surface of the parasite at the end of its penetration phase into human erythrocytes, in the occurrence of an infectious cycle. Said recombinant protein is applicable to the production of vaccines against malaria.
摘要翻译： 本发明涉及在杆状病毒系统中制备的重组蛋白质，其中必需组成型多肽序列是裂殖子虫寄生虫的表面蛋白1（蛋白质MSP-1）的19千道尔顿（p19）的C末端片段 疟原虫类型，特别是对人感染的恶性疟原虫，说在发生感染性循环时，C末端片段通常在其穿透期结束时在寄生虫的表面锚定在人红细胞中。 所述重组蛋白适用于生产针对疟疾的疫苗。
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