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公开(公告)号：US20250009503A1
公开(公告)日：2025-01-09
申请号：US18891007
申请日：2024-09-20
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Noa Axelrod Manela , Michael Bukin , Noam Nir , Eran Goldberg
Abstract: The present disclosure relates to prosthetic valves that include valvular structures retained between two frames coupled to each other. In an example, the prosthetic valve includes a main frame, an inner frame which is disposed radially inwardly from, and is coupled to, the main frame, and a valvular structure disposed between the main frame and the inner frame. The main frame is movable between a radially compressed state and a radially expanded state. The inner frame comprises a plurality of struts and a plurality of spikes extending from at least some of the plurality of struts. The plurality of spikes are engaged with the valvular structure.
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公开(公告)号：US20230255770A1
公开(公告)日：2023-08-17
申请号：US18138651
申请日：2023-04-24
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： David Maimon , Liron Tayeb , Eran Goldberg
CPC classification number: A61F2/2439 , A61F2/2433 , A61F2/2427 , A61M25/0023 , A61M2025/0024 , A61F2/9517
Abstract: The active introducer sheath systems disclosed herein are expanded by activating a translation mechanism at the handle. The sheath has an inner cylindrical structure of comingled fixed and mobile elongate rods bound together by an attachment line. Activating the translation mechanism causes the mobile rods to move axially with respect to the fixed rods, changing the internal tension in the attachment line. Increased tension draws the fixed and mobile rods closer together, decreasing the diameter of the cylindrical structure. Decreased tension in the attachment line enables the fixed and mobile rods to move apart, increasing the diameter of the cylindrical structure. A prosthetic device, such as a prosthetic heart valve, can be routed through the expanded sheath and to the implantation site. During implantation, the sheath can be contracted back to its original outer diameter, and expanded again for retrieval of the delivery apparatus.
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公开(公告)号：US20230190462A1
公开(公告)日：2023-06-22
申请号：US17892654
申请日：2022-08-22
Applicant: Edwards Lifesciences Corporation
Inventor： Noam Nir , Eran Goldberg , Michael Bukin
IPC: A61F2/24
CPC classification number: A61F2/243 , A61F2/2418
Abstract: An implantable prosthetic device can include a hybrid frame movable between a radially compressed configuration and a radially expanded configuration. The hybrid frame can include a mechanically-expandable first sub-frame comprising a plurality of struts pivotably coupled to one another, and a self-expanding second sub-frame coupled to the first sub-frame. When the hybrid frame is in the expanded configuration, the second sub-frame can be configured to resist radial compression of the frame.
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公开(公告)号：US20230113534A1
公开(公告)日：2023-04-13
申请号：US18065213
申请日：2022-12-13
Applicant: Edwards Lifesciences Corporation
Inventor： Eyal Leiba , Eran Goldberg
IPC: A61F2/24
Abstract: The present embodiments relate generally to devices, systems, and methods for delivery systems including nose cones. A delivery system may include a handle and an elongate shaft coupled to the handle. The delivery system may include a nose cone having a distal opening at a distal end and a proximal opening at a proximal end, the proximal opening configured to receive the distal end of the elongate shaft. Projections or threads may couple the nose cone to the distal end of the elongate shaft.
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公开(公告)号：US20220233310A1
公开(公告)日：2022-07-28
申请号：US17716882
申请日：2022-04-08
Applicant: Edwards Lifesciences Corporation
Inventor： Yair A. Neumann , Eran Goldberg , Anatoly Dvorsky
Abstract: Expandable sheaths are disclosed herein. In some embodiments, a braided layer is positioned radially outward from a first polymeric layer. The braided layer includes a plurality of filaments braided together. A second polymeric layer is positioned radially outward of the braided layer, such that the braided layer is encapsulated between the first and second polymeric layers. In some embodiments, a braided layer is adhered to a sealing layer that is impermeable to blood flow. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.
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Patent Agency Ranking
公开(公告)号：US20220226110A1
公开(公告)日：2022-07-21
申请号：US17657732
申请日：2022-04-01
Applicant: Edwards Lifesciences Corporation
Inventor： Liron Tayeb , Eran Goldberg , David Maimon , Adi Carmi , Arie Tylis , Ralph Schneider , Mohammad Jafari , Hengchu Cao , Eitan Atias
IPC: A61F2/24
Abstract: An expandable docking station includes an annular valve seat having an end, an annular outer wall comprising struts disposed around the valve seat, and links that connect the end of the annular valve seat to the annular outer wall. Each of the links extends from the struts of the annular outer wall directly toward a longitudinal axis that runs longitudinally through a center of the docking station, and to a corresponding one of a plurality of circumferentially spaced axially extending legs at least partially defining the annular valve seat. The outer wall is configured to conform to an interior shape of a blood vessel, when expanded inside the blood vessel, such that the outer wall can expand in multiple locations to conform to multiple bulges of the blood vessel and can contract in multiple locations to conform to multiple narrowed regions of the blood vessel.
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公开(公告)号：US11331189B2
公开(公告)日：2022-05-17
申请号：US16669447
申请日：2019-10-30
Applicant: Edwards Lifesciences Corporation
Inventor： Arie Tylis , Nikolay Gurovich , Eran Goldberg , Boaz Manash , Dan Rottenberg , Hagar Adika , Tal Regev , Dikla Kersh , Danny M. Garmahi , Hernan Altman , Amir Blumenfeld
Abstract: An anchoring system and related methods are provided for treatment of dilated hearts and of functional valve regurgitation, the system comprising one or more self-expandable or manually expandable anchors and associated devices for fixating a valve splint within the heart. For example, a spade-shaped assembly may be configured to be deployed in a right ventricle of the heart and to stabilize a puncturing instrument to puncture the septum. Various puncturing instruments may also be part of the anchoring system, including one or more of a flexible needle having a multiplicity of slits disposed along the length of the needle, a trocar catheter with a retractable head, and a catheter needle having a blunt introducer to protect nearby tissue within the heart during advancing a guidewire. A cutter catheter and puncture location catheter may also be part of the system and be used during treatment.
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公开(公告)号：US11298889B2
公开(公告)日：2022-04-12
申请号：US16294761
申请日：2019-03-06
Applicant: Edwards Lifesciences Corporation
Inventor： Itai Pelled , Elena Sherman , Eran Goldberg , Kevin D. Rupp , Noam Nir
Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration comprises an annular frame having an inflow end and an outflow end, a leaflet structure positioned within the frame and secured thereto, and a laminate sealing member comprising an encapsulating material. The laminate sealing member has a main portion that encapsulates at least a portion of the frame and an end portion extending from the inflow end of the frame, and the end portion of the laminate sealing member is folded to form a cuff adjacent the inflow end of the frame and secured to the main portion of the laminate sealing member.
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公开(公告)号：US11273062B2
公开(公告)日：2022-03-15
申请号：US16378417
申请日：2019-04-08
Applicant: Edwards Lifesciences Corporation
Inventor： Eran Goldberg , Noa Axelrod , Yair A. Neumann , Boaz Manash , David Maimon , Eyal Leiba , Ralph Schneider , Liron Tayeb
IPC: A61F2/966 , A61M25/00 , B29D23/00 , A61F2/24 , A61F2/95 , A61F2/958 , B29K105/08 , A61M29/00 , A61F2/962
Abstract: An expandable sheath is disclosed herein, which has a first polymeric layer and a braided layer positioned radially outward of the first polymeric layer. The braided layer includes a plurality of filaments braided together. The expandable sheaths further include a resilient elastic layer positioned radially outward of the braided layer. The elastic layer is configured to apply radial force to the braided layer and the first polymeric layer. The expandable sheath further includes a second polymeric layer positioned radially outward of the elastic layer and bonded to the first polymeric layer such that the braided layer and the elastic layer are encapsulated between the first and second polymeric layers. Methods of making and using the devices disclosed herein are also disclosed, as are crimping devices that may be used in methods of making the devices disclosed herein.
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公开(公告)号：US10555814B2
公开(公告)日：2020-02-11
申请号：US15353666
申请日：2016-11-16
Applicant: Edwards Lifesciences Corporation
Inventor： Noa Axelrod , Oren Wintner , Eran Goldberg , Dikla Kersh , Danny Garnahi , Dan Rottenberg , Boaz Manash
Abstract: Ultrasound probe systems and methods for using an ultrasound probe to assist during treatment of conditions of the human heart are provided. The method may comprise loading a medical instrument into a guide fastened to the ultrasound probe. The ultrasound probe may be inserted into a patient by way of an incision. The distal end of the ultrasound probe may be navigated to a location adjacent to an exterior surface of the heart. A treatment site may be identified on the exterior surface of the heart based on images obtained from an ultrasound transducer disposed within a distal end of the ultrasound probe. The medical instrument may be advanced within the guide to the treatment site and the medical instrument used for treatment. After treatment, the medical instrument may be withdrawn from the treatment site.
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