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公开(公告)号：US10465222B2
公开(公告)日：2019-11-05
申请号：US15974429
申请日：2018-05-08
申请人： EVOLVA SA
发明人： Yaoquan Liu , Jorgen Hansen , Jens Houghton-Larsen , Muthuswamy Panchapagesa Murali , Sathish Kumar , Nina Nicoline Rasmussen
IPC分类号： C12P33/20 , C12N9/10 , C12P19/18 , C12P19/56 , C12P33/08 , C12N9/02 , C12N9/14 , C12N9/90 , C12P33/00 , C12P33/12 , C12N15/80
摘要： The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention.
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公开(公告)号：US11091787B2
公开(公告)日：2021-08-17
申请号：US16806812
申请日：2020-03-02
申请人： Evolva SA
发明人： Jens Houghton-Larsen , Katarzyna Krzystanek , Angelika Semmler , Iver Klavs Riishede Hansen , Soren Damkiaer , Yaoquan Liu , Jorgen Hansen , Sathish Kumar , Muthuswamy Panchapagesa Murali , Nina Nicoline Rasmussen
IPC分类号： C12P33/00 , C12P19/56 , C12P19/18 , C12N9/14 , C12N9/10 , C12N9/06 , C12N9/90 , C12N9/02 , A23L27/30 , C07H1/06 , C12N15/00
摘要： Methods for recombinant and enzymatic production of mogroside compounds and compositions containing mogroside compounds are provided by this invention.
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公开(公告)号：US09932619B2
公开(公告)日：2018-04-03
申请号：US14442694
申请日：2013-12-04
申请人： Evolva SA
发明人： Yaoquan Liu , Jorgen Hansen , Jens Houghton-Larsen , Muthuswamy Panchapagesa Murali , Sathish Kumar , Nina Nicoline Rasmussen
IPC分类号： C12P33/20 , C12P19/18 , C12P19/56 , C12N1/00 , C12N9/10 , C12P33/08 , C12N9/02 , C12N9/14 , C12N9/90 , C12P33/00 , C12P33/12 , C12N15/80
CPC分类号： C12P33/20 , C12N9/0071 , C12N9/0073 , C12N9/1048 , C12N9/14 , C12N9/90 , C12N15/80 , C12P19/18 , C12P19/56 , C12P33/00 , C12P33/08 , C12P33/12 , C12Y114/00 , C12Y114/13132 , C12Y303/00 , C12Y504/99033
摘要： The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention.
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公开(公告)号：US20170306376A1
公开(公告)日：2017-10-26
申请号：US15589269
申请日：2017-05-08
申请人： EVOLVA SA
发明人： Shriram Raghavan , Jorgen Hansen , Shailendra Sonkar , Sathish Kumar , Kalyan Kumar , Murali Panchapagesa , Esben Hansen , Klavs Riishede Hansen
CPC分类号： C12P19/46 , C12N9/0006 , C12N9/1048 , C12N9/1051
摘要： Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a zeaxanthin cleavage dioxygenase alone or in combination with recombinant genes encoding UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce compounds from saffron such as crocetin, crocetin dialdehyde, crocin, or picrocrocin.
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公开(公告)号：US10662458B2
公开(公告)日：2020-05-26
申请号：US15900557
申请日：2018-02-20
申请人： EVOLVA SA
发明人： Yaoquan Liu , Jorgen Hansen , Jens Houghton-Larsen , Muthuswamy Panchapagesa Murali , Sathish Kumar , Nina Nicoline Rasmussen
IPC分类号： C12P19/18 , C12P33/20 , C12N9/10 , C12P19/56 , C12P33/08 , C12N9/02 , C12N9/14 , C12N9/90 , C12P33/00 , C12P33/12 , C12N15/80
摘要： The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention.
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公开(公告)号：US20180251806A1
公开(公告)日：2018-09-06
申请号：US15900557
申请日：2018-02-20
申请人： EVOLVA SA
发明人： Yaoquan Liu , Jorgen Hansen , Jens Houghton-Larsen , Muthuswamy Panchapagesa Murali , Sathish Kumar , Nina Nicoline Rasmussen
IPC分类号： C12P33/20 , C12N9/02 , C12P33/12 , C12P33/08 , C12P33/00 , C12P19/56 , C12P19/18 , C12N9/90 , C12N9/14 , C12N9/10 , C12N15/80
摘要： The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention.
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公开(公告)号：US20170247735A1
公开(公告)日：2017-08-31
申请号：US15511565
申请日：2015-09-30
申请人： Evolva SA
发明人： Jens Houghton-Larsen , Katarzyna Krzystanek , Angelika Semmler , Iver Klavs Riishede Hansen , Soren Damkiaer , Gary Liu , Yaoquan Liu , Jorgen Hansen , Sathish Kumar , Muthuswamy Panchapagesa Murali , Nina Nicoline Rasmussen
CPC分类号： C12P33/00 , A23L27/36 , A23V2002/00 , C07H1/06 , C12N9/0014 , C12N9/0042 , C12N9/0071 , C12N9/0073 , C12N9/1051 , C12N9/14 , C12N9/90 , C12N15/00 , C12P19/18 , C12P19/56
摘要： Methods for recombinant and enzymatic production of mogroside compounds and compositions containing mogroside compounds are provided by this invention.
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公开(公告)号：US20180346953A1
公开(公告)日：2018-12-06
申请号：US15974429
申请日：2018-05-08
申请人： EVOLVA SA
发明人： Yaoquan Liu , Jorgen Hansen , Jens Houghton-Larsen , Muthuswamy Panchapagesa Murali , Sathish Kumar , Nina Nicoline Rasmussen
IPC分类号： C12P33/20 , C12N9/02 , C12P33/12 , C12P33/08 , C12P33/00 , C12P19/56 , C12P19/18 , C12N9/90 , C12N9/14 , C12N9/10 , C12N15/80
CPC分类号： C12P33/20 , C12N9/0071 , C12N9/0073 , C12N9/1048 , C12N9/14 , C12N9/90 , C12N15/80 , C12P19/18 , C12P19/56 , C12P33/00 , C12P33/08 , C12P33/12 , C12Y114/00 , C12Y114/13132 , C12Y303/00 , C12Y504/99033
摘要： The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention.
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公开(公告)号：US20150322473A1
公开(公告)日：2015-11-12
申请号：US14442694
申请日：2013-12-04
申请人： EVOLVA SA
发明人： Yaoquan Liu , Jorgen Hansen , Jens Houghton-Larsen , Muthuswamy Panchapagesa Murali , Sathish Kumar , Nina Nicoline Rasmussen
CPC分类号： C12P33/20 , C12N9/0071 , C12N9/0073 , C12N9/1048 , C12N9/14 , C12N9/90 , C12N15/80 , C12P19/18 , C12P19/56 , C12P33/00 , C12P33/08 , C12P33/12 , C12Y114/00 , C12Y114/13132 , C12Y303/00 , C12Y504/99033
摘要： The invention relates to methods for producing mogrosides with the aid of enzymes. In particular the invention proposes various biosynthetic pathways useful for mogroside production and enzymes useful for mogroside production are provided. Furthermore, the invention provides recombinant hosts useful in performing the methods of the invention.
摘要翻译： 本发明涉及借助于酶的方法来生产芒果苷。 特别地，本发明提出了可用于罗汉果苷生产的各种生物合成途径，并提供了可用于罗汉果苷生产的酶。 此外，本发明提供可用于实施本发明方法的重组宿主。
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公开(公告)号：US20200325517A1
公开(公告)日：2020-10-15
申请号：US16806812
申请日：2020-03-02
申请人： Evolva SA
发明人： Jens Houghton-Larsen , Katarzyna Krzystanek , Angelika Semmler , Iver Klavs Riishede Hansen , Soren Damkiaer , Yaoquan Liu , Jorgen Hansen , Sathish Kumar , Muthuswamy Panchapagesa Murali , Nina Nicoline Rasmussen
IPC分类号： C12P33/00 , C12P19/56 , C12P19/18 , C12N9/14 , C12N9/10 , C12N9/06 , C12N9/90 , C12N9/02 , A23L27/30 , C07H1/06 , C12N15/00
摘要： Methods for recombinant and enzymatic production of mogroside compounds and compositions containing mogroside compounds are provided by this invention.
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