公开(公告)号：US20130190563A1

公开(公告)日：2013-07-25

申请号：US13743469

申请日：2013-01-17

Applicant: GIVEN IMAGING LTD.

Inventor： Amit PASCAL

IPC: G02B5/20 ,  H04N5/232 ,  A61B1/04

CPC classification number: G02B5/201 ,  A61B1/00186 ,  A61B1/00188 ,  A61B1/041 ,  G02B27/0075 ,  G02B2207/129 ,  H04N5/23212

Abstract: A system and method for acquiring images containing spatial and spectral information of an object include acquiring defocused images using an optical system based on extended depth of field. The optical system further includes a filter array comprising an array of at least six different sub-filters that are arranged such that any group of four immediately adjacent sub-filters includes at least one red sub-filter, at least one green sub-filter and at least one blue sub-filter. The filter array is located at the aperture stop of the optical system. A coded mask is located at the focal plane of the optical system, and an imager is located beyond the focal plane such that images acquired by the imager are defocused. The images are refocused, and spectral and spatial information is restored by designated software.

Abstract translation: 用于获取包含对象的空间和光谱信息的图像的系统和方法包括使用基于扩展景深的光学系统获取散焦图像。 该光学系统还包括一个滤波器阵列，该滤波器阵列包括至少六个不同的子滤波器的阵列，其被布置为使得四个紧邻的子滤波器的任何组包括至少一个红色子滤波器，至少一个绿色子滤波器和 至少一个蓝色子滤镜。 滤光片阵列位于光学系统的孔径光阑处。 编码掩模位于光学系统的焦平面处，并且成像器位于焦平面之外，使得由成像器获取的图像散焦。 图像被重新聚焦，并且通过指定的软件恢复光谱和空间信息。

公开(公告)号：US20180160950A1

公开(公告)日：2018-06-14

申请号：US15578505

申请日：2016-06-02

Applicant: GIVEN IMAGING LTD.

Inventor： Elisha RABINOVITZ ,  Osnat SELLA-TAVOR ,  Amit PASCAL

IPC: A61B5/145 ,  A61B5/01 ,  A61B5/05 ,  A61B5/07 ,  A61B5/1486

CPC classification number: A61B5/14507 ,  A61B5/01 ,  A61B5/05 ,  A61B5/073 ,  A61B5/14503 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/14865 ,  A61B5/4216 ,  A61B5/6861 ,  A61B2562/0295 ,  A61B2562/162 ,  A61B2562/166 ,  G01N33/558

Abstract: A swallowable in-vivo device comprising a shell formed with at least one inlet extending across a shell wall and configured for allowing ingress of fluid at least into the shell; the shell accommodates therein a lateral flow (LF) arrangement configured for absorbing the fluid; the LF arrangement comprises a test zone configured for coming into contact, in-vivo, with a predetermined N substance present in the fluid or a compound comprising the substance, thereby causing a change in at least one property of the test zone; the shell further accommodates a sensor configured for sensing, in-vivo, the at least one property, at least when changed by interaction with the fluid; the LF arrangement has at least one curved segment, and at least one exposure portion juxtaposed with the inlet, configured for absorbing the fluid passing through the inlet into the shell.

公开(公告)号：US20160192833A1

公开(公告)日：2016-07-07

申请号：US15071248

申请日：2016-03-16

Applicant: GIVEN IMAGING LTD.

Inventor： Amit PASCAL ,  Zvika GILAD ,  Haim BEZDIN

IPC: A61B1/06 ,  A61B1/04

CPC classification number: A61B1/0661 ,  A61B1/041 ,  A61B1/051 ,  A61B1/0607 ,  A61B1/0676

Abstract: The invention provides a device for in-vivo imaging, for example, using an in-vivo imaging device including an imager a lens and an illumination source, all positioned behind a single viewing window. The in-vivo imaging device may include an element to block light from reaching a point of reflection on the inner surface of the viewing window, thereby preventing the light from being received by the imager.

Abstract translation: 本发明提供一种用于体内成像的装置，例如，使用包括成像器的体内成像装置的透镜和照明源，所述装置全部位于单个观察窗后。 体内成像装置可以包括阻挡光到达观察窗的内表面上的反射点的元件，从而防止光被成像器接收。

公开(公告)号：US20140296666A1

公开(公告)日：2014-10-02

申请号：US14304690

申请日：2014-06-13

Applicant: GIVEN IMAGING LTD.

Inventor： ELISHA RABINOVITZ ,  Zvika GILAD ,  Amit PASCAL ,  Yaniv BIRNBOIM ,  Gavriel J. IDDAN ,  Daniel GAT ,  Hagai KRUPNIK ,  Ori BRAUN ,  Dan ROTTENBERG ,  Omer SHEZIFI ,  Yosi PESIS ,  Dima PINHASOV ,  Evgeny KAPILOV ,  Nir LILACH ,  Eliahu ELIACHAR ,  Oren COHEN ,  Daniel GAMZU

IPC: A61B5/1459

CPC classification number: A61B5/1459 ,  A61B1/041 ,  A61B1/063 ,  A61B1/0684 ,  A61B5/0084 ,  A61B5/073

Abstract: In-vivo devices, systems and methods for the detection of blood within in-vivo bodily fluids. The methods include irradiating in-vivo fluids passing through a gap in a housing of an in-vivo device introduced to the GI tract of a subject with a plurality of illumination sources positioned on a first side of a gap; detecting with at least one light detector positioned on the opposite side of the gap and facing the illumination sources, light irradiated by the illumination sources; transmitting a plurality of values representing the light detected over time; converting these values to blood concentration values over time, and comparing the blood concentration values to a predetermined threshold value. Based on the comparison, the method includes determining the type of bleeding profile, such that if a plurality of blood concentration values measured consecutively is above the threshold value, the bleeding profile indicates bleeding.

Abstract translation: 用于检测体内体液内的血液的体内装置，系统和方法。 所述方法包括：照射通过定位在间隙的第一侧上的多个照明源的通过被导入到对象的胃肠道的体内装置的壳体中的间隙的体内流体; 用位于所述间隙的相对侧上并且面对所述照明源的至少一个光检测器检测由所述照明源照射的光; 发送表示随时间检测到的光的多个值; 将这些值随时间转换为血液浓度值，并将血液浓度值与预定阈值进行比较。 基于比较，该方法包括确定出血分布的类型，使得如果连续测量的多个血液浓度值高于阈值，则出血分布指示出血。