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公开(公告)号:US06892085B2
公开(公告)日:2005-05-10
申请号:US10304518
申请日:2002-11-26
申请人: K. Collin McIvor , James L. Cabernoch , Kevin D. Branch , Nannette M. Van Antwerp , Edgardo C. Halili , John J. Mastrototaro
发明人: K. Collin McIvor , James L. Cabernoch , Kevin D. Branch , Nannette M. Van Antwerp , Edgardo C. Halili , John J. Mastrototaro
IPC分类号: G01N27/28 , A61B5/00 , A61B5/145 , A61B5/1473 , A61B5/1486 , B65B55/02 , C12M1/40 , G01N27/327 , G01N27/416 , A61B5/05 , A61B5/04
CPC分类号: A61B5/14865 , A61B5/14532 , A61B5/6849
摘要: A glucose sensor package system that includes a glucose sensor and a protective package that indicates exposure to temperature changes to indicate proper temperature control. Also covered are methods of transporting and sterilizing the package. In addition, glucose sensors directed to various sizing and positioning of the electrodes on the glucose sensor are covered.
摘要翻译: 一种葡萄糖传感器包装系统,其包括葡萄糖传感器和保护包,其指示暴露于温度变化以指示适当的温度控制。 还包括运输和消毒包装的方法。 此外,还覆盖了针对葡萄糖传感器上的电极的各种尺寸和定位的葡萄糖传感器。
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公开(公告)号:US06520326B2
公开(公告)日:2003-02-18
申请号:US09973852
申请日:2001-10-09
申请人: K. Collin McIvor , James L. Cabernoch , Kevin D. Branch , Nannette M. Van Antwerp , Edgardo C. Halili , John J. Mastrototaro
发明人: K. Collin McIvor , James L. Cabernoch , Kevin D. Branch , Nannette M. Van Antwerp , Edgardo C. Halili , John J. Mastrototaro
IPC分类号: A61B502
CPC分类号: A61B5/14865 , A61B5/14532 , A61B5/6849
摘要: A glucose sensor package system that includes a glucose sensor and a protective package that indicates exposure to temperature changes to indicate proper temperature control. Also covered are methods of transporting and sterilizing the package. In addition, glucose sensors directed to various sizing and positioning of the electrodes on the glucose sensor are covered.
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公开(公告)号:US06360888B1
公开(公告)日:2002-03-26
申请号:US09501848
申请日:2000-02-10
申请人: K. Collin McIvor , James L. Cabernoch , Kevin D. Branch , Nannette M. Van Antwerp , Edgardo C. Halili , John J. Mastrototaro
发明人: K. Collin McIvor , James L. Cabernoch , Kevin D. Branch , Nannette M. Van Antwerp , Edgardo C. Halili , John J. Mastrototaro
IPC分类号: B65D8538
CPC分类号: A61B5/14865 , A61B5/14532 , A61B5/6849
摘要: A glucose sensor package system that includes a glucose sensor and a protective package that indicates exposure to temperature changes to indicate proper temperature control. Also covered are methods of transporting and sterilizing the package. In addition, glucose sensors directed to various sizing and positioning of the electrodes on the glucose sensor are covered.
摘要翻译: 一种葡萄糖传感器包装系统,其包括葡萄糖传感器和保护包,其指示暴露于温度变化以指示适当的温度控制。 还包括运输和消毒包装的方法。 此外,还覆盖了针对葡萄糖传感器上的电极的各种尺寸和定位的葡萄糖传感器。
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公开(公告)号:US5779665A
公开(公告)日:1998-07-14
申请号:US848476
申请日:1997-05-08
CPC分类号: A61B5/14532 , A61B5/6849 , A61M25/0606
摘要: A transdermal introducer assembly is provided for quick and easy transcutaneous placement of a medical tube on a patient with reduced patient discomfort. The introducer assembly comprises a medical tube segment defining a hollow lumen extending between a distal end for placement into the subcutaneous tissue and a proximal end disposed outside the patient. The tube segment is assembled in side-by-side relation with a hollow introducer needle, and includes an elongated introducer thread at the distal end thereof folded back for slide-fit reception into the open distal end of the introducer needle. In use, the introducer needle is deployed to pierce the patient's skin at a selected placement site and to carry the tube segment to the desired transcutaneous position, after which the introducer needle can be withdrawn and slidably separated from the introducer thread to leave the tube segment and thread in place on the patient. A window is formed in the tube segment near the distal end thereof and, in a preferred form, exposes a transcutaneous sensor carried within the tube segment to patient body fluids.
摘要翻译: 提供了一种透皮引导器组件,用于快速且容易地经皮地将医疗管放置在患者身上,减少了患者的不适。 导引器组件包括限定在远端之间延伸以放置到皮下组织中的中空腔的医疗管段和设置在患者外部的近端。 管段与中空导引针并列组装,并且在其远端处包括细长的导引线,其折回以用于滑动配合接收到导引针的开放远端中。 在使用中,引导器针被展开以在选定的放置位置刺穿患者的皮肤并将管段运送到期望的经皮位置,之后引导器针可以被拉出并与导引线滑动分离以离开管段 并将线穿在患者身上。 在管段中在其远端附近形成窗口,并且以优选形式将携带在管段内的经皮传感器暴露于患者体液。
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公开(公告)号:US07468033B2
公开(公告)日:2008-12-23
申请号:US10935954
申请日:2004-09-08
申请人: Nannette M. Van Antwerp , Bradley J. Enegren , John J. Mastrototaro , Rajiv Shah , Udo Hoss , Yanan Zhang , Jenn-Hann Wang , Kent L. Clark
发明人: Nannette M. Van Antwerp , Bradley J. Enegren , John J. Mastrototaro , Rajiv Shah , Udo Hoss , Yanan Zhang , Jenn-Hann Wang , Kent L. Clark
CPC分类号: A61B5/153 , A61B5/0002 , A61B5/14532 , A61B5/15003 , A61B5/150755 , A61B5/150862 , A61B5/150992
摘要: The invention provides methods and apparatus for detecting an analyte in blood. The apparatus is particularly suited for bringing a sensor into direct contact with blood in vivo. The apparatus comprises a sensor that detects the presence of an analyte and an assembly means. The assembly means has a sensor end, wherein the sensor end of the assembly means is affixed to the sensor, and the assembly means is adapted for coupling with a venous flow device. By coupling with a venous flow device, the assembly means brings the sensor into direct contact with blood flowing through the venous flow device. Examples of venous flow devices that bring the sensor into direct contact with the blood of a subject include, but are not limited to, intravenous catheters and external blood loops, such as are used in extra corporeal membrane oxygenation or hemodialysis.
摘要翻译: 本发明提供了用于检测血液中分析物的方法和装置。 该装置特别适于使传感器在体内与血液直接接触。 该装置包括检测分析物和组装装置的存在的传感器。 组装装置具有传感器端,其中组装装置的传感器端固定到传感器,并且组装装置适于与静脉流装置联接。 通过与静脉流动装置联接,组装装置使传感器与流过静脉流装置的血液直接接触。 将传感器与受试者的血液直接接触的静脉流动装置的实例包括但不限于静脉内导管和外部血液回路,例如用于额外的体外膜氧合或血液透析。
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公开(公告)号:USD469540S1
公开(公告)日:2003-01-28
申请号:US29153333
申请日:2001-11-07
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公开(公告)号:USD452323S1
公开(公告)日:2001-12-18
申请号:US29127124
申请日:2000-07-31
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公开(公告)号:US20090149728A1
公开(公告)日:2009-06-11
申请号:US12264810
申请日:2008-11-04
申请人: Nannette M. Van Antwerp , Bradley J. Enegren , John J. Mastrototaro , Rajiv Shah , Udo Hoss , Yanan Zhang , Jenn-Hann Wang , Kent L. Clark
发明人: Nannette M. Van Antwerp , Bradley J. Enegren , John J. Mastrototaro , Rajiv Shah , Udo Hoss , Yanan Zhang , Jenn-Hann Wang , Kent L. Clark
IPC分类号: A61B5/1468
CPC分类号: A61B5/153 , A61B5/0002 , A61B5/14532 , A61B5/15003 , A61B5/150755 , A61B5/150862 , A61B5/150992
摘要: The invention provides methods and apparatus for detecting an analyte in blood. The apparatus is particularly suited for bringing a sensor into direct contact with blood in vivo. The apparatus comprises a sensor that detects the presence of an analyte and an assembly means. The assembly means has a sensor end, wherein the sensor end of the assembly means is affixed to the sensor, and the assembly means is adapted for coupling with a venous flow device. By coupling with a venous flow device, the assembly means brings the sensor into direct contact with blood flowing through the venous flow device. Examples of venous flow devices that bring the sensor into direct contact with the blood of a subject include, but are not limited to, intravenous catheters and external blood loops, such as are used in extra corporeal membrane oxygenation or hemodialysis.
摘要翻译: 本发明提供了用于检测血液中分析物的方法和装置。 该装置特别适于使传感器在体内与血液直接接触。 该装置包括检测分析物和组装装置的存在的传感器。 组装装置具有传感器端,其中组装装置的传感器端固定到传感器,并且组装装置适于与静脉流装置联接。 通过与静脉流动装置联接,组装装置使传感器与流过静脉流装置的血液直接接触。 将传感器与受试者的血液直接接触的静脉流动装置的实例包括但不限于静脉内导管和外部血液回路,例如用于额外的体外膜氧合或血液透析。
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公开(公告)号:US07247138B2
公开(公告)日:2007-07-24
申请号:US10365279
申请日:2003-02-12
申请人: Bahar Reghabi , Rajiv Shah , Eunjoo Jin , Rebecca Gottlieb , Michael E. Miller , Nannette M. Van Antwerp , Bradley J. Enegren , William P. Van Antwerp , John J. Mastrototaro
发明人: Bahar Reghabi , Rajiv Shah , Eunjoo Jin , Rebecca Gottlieb , Michael E. Miller , Nannette M. Van Antwerp , Bradley J. Enegren , William P. Van Antwerp , John J. Mastrototaro
CPC分类号: A61B5/14532 , A61B5/076 , A61B5/14503 , A61B5/14546 , A61B5/1459 , A61B5/14865 , A61M39/0208
摘要: A reusable analyte sensor site for use with a replaceable analyte sensor for determining a level of an analyte includes a site housing material and a resealable insertion site coupled to one end of the site housing material. Preferably, the site housing material is formed to have an interior cavity with an opening. The site housing material is selected to promote tissue ingrowth and vascularization, and yet be free of tissue ingress. Also, the site housing material permits the analyte to pass through the site housing material to the interior cavity to permit measurement by the replaceable analyte sensor. The resealable insertion site provides a for inserting the replaceable analyte sensor into the interior cavity of the site housing material.
摘要翻译: 与用于确定分析物水平的可更换分析物传感器一起使用的可重复使用的分析物传感器位点包括与场地外壳材料的一端连接的部位外壳材料和可重新密封的插入位置。 优选地,所述场地外壳材料形成为具有带有开口的内部空腔。 选择场地外壳材料以促进组织向内生长和血管形成,并且没有组织进入。 此外,现场外壳材料允许分析物通过现场外壳材料通过内部空腔,以允许通过可更换的分析物传感器进行测量。 可重新密封的插入位置提供用于将可更换的分析物传感器插入到场地外壳材料的内部空腔中。
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公开(公告)号:US08352011B2
公开(公告)日:2013-01-08
申请号:US12264810
申请日:2008-11-04
申请人: Nannette M. Van Antwerp , Bradley J. Enegren , John J. Mastrototaro , Rajiv Shah , Udo Hoss , Yanan Zhang , Jenn-Hann Larry Wang , Kent L. Clark
发明人: Nannette M. Van Antwerp , Bradley J. Enegren , John J. Mastrototaro , Rajiv Shah , Udo Hoss , Yanan Zhang , Jenn-Hann Larry Wang , Kent L. Clark
IPC分类号: A61B5/05
CPC分类号: A61B5/153 , A61B5/0002 , A61B5/14532 , A61B5/15003 , A61B5/150755 , A61B5/150862 , A61B5/150992
摘要: The invention provides methods and apparatus for detecting an analyte in blood. The apparatus is particularly suited for bringing a sensor into direct contact with blood in vivo. The apparatus comprises a sensor that detects the presence of an analyte and an assembly means. The assembly means has a sensor end, wherein the sensor end of the assembly means is affixed to the sensor, and the assembly means is adapted for coupling with a venous flow device. By coupling with a venous flow device, the assembly means brings the sensor into direct contact with blood flowing through the venous flow device. Examples of venous flow devices that bring the sensor into direct contact with the blood of a subject include, but are not limited to, intravenous catheters and external blood loops, such as are used in extra corporeal membrane oxygenation or hemodialysis.
摘要翻译: 本发明提供了用于检测血液中分析物的方法和装置。 该装置特别适于使传感器在体内与血液直接接触。 该装置包括检测分析物和组装装置的存在的传感器。 组装装置具有传感器端,其中组装装置的传感器端固定到传感器,并且组装装置适于与静脉流装置联接。 通过与静脉流动装置联接,组装装置使传感器与流过静脉流装置的血液直接接触。 将传感器与受试者的血液直接接触的静脉流动装置的实例包括但不限于静脉内导管和外部血液回路,例如用于额外的体外膜氧合或血液透析。
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