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公开(公告)号：US5211913A
公开(公告)日：1993-05-18
申请号：US288868
申请日：1988-12-23
CPC分类号： B01D67/0088 , A61L33/064 , A61L33/068 , A61M1/325 , A61M1/3627 , A61M1/3643 , B01D19/0031 , B01D63/02 , B01D67/0093 , A61M2205/366 , B01D2313/50 , Y10T428/1352
摘要： The blood flow channel sections of an oxygenator and a blood reservoir are hydrophilized by treatment with an acid, an albumin solution, polyhydroxy methacrylate, corona discharge, plasma or ozone, so that it has highly improved wettability by the priming liquid and the blood to prevent blood foaming. The blood flow channel sections of a medical instrument may be additionally hydrophilized by treatment with a polymer containing hydroxyethyl methacrylate and methyl methacrylate or in addition thereto a poly(oxyethylene)-poly(oxypropylene) block polymer.
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公开(公告)号：US5582794A
公开(公告)日：1996-12-10
申请号：US439240
申请日：1995-05-11
CPC分类号： B01D67/0088 , A61L33/064 , A61L33/068 , A61M1/325 , A61M1/3627 , A61M1/3643 , B01D19/0031 , B01D63/02 , B01D67/0093 , A61M2205/366 , B01D2313/50 , Y10T428/1352
摘要： The blood flow channel sections of an oxygenator and a blood resevoir are hydrophilized by treatment with an acid, an albumin solution, polyhydroxy methacrylate, corona discharge, plasma or ozone, so that it has highly improved weltability by the priming liquid and the blood to prevent blood foaming. The blood flow channel sections of a medical instrument may be additionally hydrophilized by treatment with a polymer containing hydroxyethyl methacrylate and methyl methacrylate or in addition thereto a poly(oxyethylene)-poly(oxypropylene) block polymer.
摘要翻译： 通过用酸，白蛋白溶液，多羟基甲基丙烯酸酯，电晕放电，等离子体或臭氧进行处理，使氧合器和血液储存器的血流通道部分亲水化，使其通过引发液体和血液具有高度改善的润湿性，以防止 血液起泡。 医疗器械的血流通道部分可以通过用含有甲基丙烯酸羟乙酯和甲基丙烯酸甲酯的聚合物或除了聚（氧乙烯） - 聚（氧丙烯）嵌段聚合物的聚合物进行处理外，还可进一步亲水化。
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公开(公告)号：US5429802A
公开(公告)日：1995-07-04
申请号：US9759
申请日：1993-01-27
CPC分类号： B01D67/0088 , A61L33/064 , A61L33/068 , A61M1/325 , A61M1/3627 , A61M1/3643 , B01D19/0031 , B01D63/02 , B01D67/0093 , A61M2205/366 , B01D2313/50 , Y10T428/1352
摘要： The blood flow channel sections of an oxygenator and a blood resevoir are hydrophilized by treatment with an acid, an albumin solution, polyhydroxy methacrylate, corona discharge, plasma or ozone, so that it has highly improved wettability by the priming liquid and the blood to prevent blood foaming. The blood flow channel sections of a medical instrument may be additionally hydrophilized by treatment with a polymer containing hydroxyethyl methacrylate and methyl methacrylate or in addition thereto a poly(oxyethylene)-poly(oxypropylene) block polymer.
摘要翻译： 通过用酸，白蛋白溶液，多羟基甲基丙烯酸酯，电晕放电，等离子体或臭氧处理使氧合器和血液储存器的血流通道部分亲水化，使得其通过引发液体和血液具有高度改善的润湿性，以防止 血液起泡。 医疗器械的血流通道部分可以通过用含有甲基丙烯酸羟乙酯和甲基丙烯酸甲酯的聚合物或除了聚（氧乙烯） - 聚（氧丙烯）嵌段聚合物的聚合物进行处理外，还可进一步亲水化。
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公开(公告)号：US4909989A
公开(公告)日：1990-03-20
申请号：US328763
申请日：1989-03-27
CPC分类号： B01D67/0088 , A61L33/064 , B01D69/141 , Y10S128/03 , Y10S261/28
摘要： In a membrane type artificial lung using as gas-exchange membranes porous hydrophobic membranes having a wall thickness in the range of 5 to 80 .mu.m, a porosity in the range of 20 to 80%, and a pore diameter in the range of 0.01 to 5 .mu.m, the minute pores of the membranes are blocked with minute particles of silica having a diameter smaller than the pore diameter and having a hydrophobic surface at least on the sides thereof intended for exposure to blood. Optionally, the gas-exchange membranes have the surfaces for exposure to blood coated with a biocompatible hydrophobic resin.
摘要翻译： 在作为气体交换膜使用的膜型人造肺中，多孔疏水膜的壁厚在5〜80μm的范围内，孔隙率在20〜80％的范围内，孔径在0.01〜 5微米，膜的微孔被直径小于孔径的微小二氧化硅颗粒阻挡，并且至少在其用于暴露于血液的侧面具有疏水表面。 任选地，气体交换膜具有暴露于用生物相容的疏水性树脂涂覆的血液的表面。
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公开(公告)号：US08352181B2
公开(公告)日：2013-01-08
申请号：US11998359
申请日：2007-11-29
申请人： Kazuhiko Hagiwara
发明人： Kazuhiko Hagiwara
CPC分类号： G08G1/0962 , G01C21/36 , G01C21/3647
摘要： In a communication type navigation system, a center apparatus receives a present position and destination from an in-vehicle navigation apparatus and thereby calculates a route by searching map data, which is constantly updated. The in-vehicle navigation apparatus receives the calculated route with course information from the center apparatus. When approaching a passing point included in the route, the navigation apparatus displays the course information in the travel direction in superimposition on a forward image around the passing point. The route guide can be thus appropriately performed to follow an actual road state. The above configuration of the system helps prevent problems in costs and workloads resulting from an in-vehicle navigation apparatus holding map data therein.
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公开(公告)号：US07630831B2
公开(公告)日：2009-12-08
申请号：US11500304
申请日：2006-08-08
申请人： Kazuhiko Hagiwara
发明人： Kazuhiko Hagiwara
CPC分类号： G01C21/3461 , G01C21/3614 , G01C21/3617
摘要： There is a need for providing a navigation system that enhances the freedom of settling time points to determine a destination. The system prompts a user to input only information needed for determining a target region (e.g., a region including several tourist spots or a region including several ski resorts) at a departure time. The system prompts a user to input information needed for determining a specific destination (e.g., a specific tourist spot, or a specific ski resort) halfway through the target region. Accordingly, the user need not determine a specific destination at the departure time.
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公开(公告)号：US5116308A
公开(公告)日：1992-05-26
申请号：US463271
申请日：1990-01-10
申请人： Kazuhiko Hagiwara
发明人： Kazuhiko Hagiwara
CPC分类号： B01J19/185 , A61M1/1006 , A61M1/1037 , A61M1/1062 , A61M1/1065 , A61M1/267 , B01D53/22 , B01D61/243 , B01D61/30 , B01D63/02 , B01D65/08 , A61M1/1698 , B01D2313/18 , B01D2313/21 , B01D2321/2083 , B01J2219/00162
摘要： Fluid in- and out-flow spaces are provided for fluid inlet and outlet of a fluid processor accommodated in housing. Further, pair wall means defining the fluid in- and out-flow spaces, a flexible member provided for deformation on at least one of the wall means, an operation chamber provided in correspondence to the flexible member, fluid pressure supply means for fluid pressure for reciprocating the flexible member and port on-off means for reverse flow prevention to direct flow of fluid from the fluid in-flow space to the fluid out-flow space are provided. Reciprocal operation of the flexible member generates fluid pressure variation in the fluid in- and out-flow spaces, thus causing flow of said fluid processor.
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公开(公告)号：US4923679A
公开(公告)日：1990-05-08
申请号：US386032
申请日：1989-07-25
CPC分类号： B01D61/38 , B01D69/141 , Y10S128/03 , Y10S261/28
摘要： A hollow fiber membrane type oxygenator is provided wherein a bundle of a plurality of hollow porous fibers presenting gas exchange membranes axially extends through a housing to define a first flow path for oxygen, a pair of partitions support the opposed open ends of the hollow fibers to isolate the open ends from the first flow path to define a second flow path through the fiber cavities for blood, and the micropores in the hollow fibers are filled with a silicone compound, for exmaple, a RTV silicone rubber or a blend thereof with a silicone oil while the hollow fibers on their side wall are substantially free of a layer of the silicone compound. The oxygenator is manufactured by prefabricating an oxygenator module of the above-mentioned construction, impregnating the hollow fibers with a solution of the silicone compound, and passing a cleaning liquid to remove excessive silicone compound, thereby filling only the micropores with the silicone compound.
摘要翻译： 提供一种中空纤维膜式充氧器，其中呈现气体交换膜的多个中空多孔纤维的一束沿轴向延伸穿过壳体以限定用于氧气的第一流动路径，一对隔板将中空纤维的相对的开放端支撑到 将开放端与第一流动路径隔离以限定通过用于血液的纤维腔的第二流动路径，并且中空纤维中的微孔填充有硅氧烷化合物，用于示例，RTV硅橡胶或其与硅氧烷的共混物 而其侧壁上的中空纤维基本上没有一层硅氧烷化合物。 氧合器通过预制上述结构的充氧器组件制造，用硅氧烷化合物的溶液浸渍中空纤维，并通过清洗液以除去过量的硅氧烷化合物，从而仅用硅氧烷化合物填充微孔。
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公开(公告)号：US20090182497A1
公开(公告)日：2009-07-16
申请号：US11998359
申请日：2007-11-29
申请人： Kazuhiko Hagiwara
发明人： Kazuhiko Hagiwara
IPC分类号： G01C21/36
CPC分类号： G08G1/0962 , G01C21/36 , G01C21/3647
摘要： In a communication type navigation system, a center apparatus receives a present position and destination from an in-vehicle navigation apparatus and thereby calculates a route by searching map data, which is constantly updated. The in-vehicle navigation apparatus receives the calculated route with course information from the center apparatus. When approaching a passing point included in the route, the navigation apparatus displays the course information in the travel direction in superimposition on a forward image around the passing point. The route guide can be thus appropriately performed to follow an actual road state. The above configuration of the system helps prevent problems in costs and workloads resulting from an in-vehicle navigation apparatus holding map data therein.
摘要翻译： 在通信型导航系统中，中心装置从车载导航装置接收当前位置和目的地，从而通过搜索不断更新的地图数据来计算路线。 车载导航装置从中心装置接收具有路线信息的计算出的路线。 当接近包括在路线中的经过点时，导航装置将行进方向上的路线信息叠加在通过点周围的前方图像上。 因此，可以适当地进行路径引导以跟随实际的道路状态。 系统的上述配置有助于防止由其中保存有地图数据的车载导航装置导致的成本和工作负荷的问题。
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公开(公告)号：US20090157297A1
公开(公告)日：2009-06-18
申请号：US11500304
申请日：2006-08-08
申请人： Kazuhiko Hagiwara
发明人： Kazuhiko Hagiwara
IPC分类号： G01C21/36
CPC分类号： G01C21/3461 , G01C21/3614 , G01C21/3617
摘要： There is a need for providing a navigation system that enhances the freedom of settling time points to determine a destination. The system prompts a user to input only information needed for determining a target region (e.g., a region including several tourist spots or a region including several ski resorts) at a departure time. The system prompts a user to input information needed for determining a specific destination (e.g., a specific tourist spot, or a specific ski resort) halfway through the target region. Accordingly, the user need not determine a specific destination at the departure time.
摘要翻译： 需要提供一种导航系统，其增强了建立时间点以确定目的地的自由度。 在出发时，系统提示用户仅输入确定目标区域所需的信息（例如包括几个旅游景点的区域或包括数个滑雪胜地的区域）。 系统提示用户输入确定目标区域中途的特定目的地（例如，特定旅游景点或特定滑雪胜地）所需的信息。 因此，用户不需要在出发时确定特定目的地。
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