公开(公告)号：US20150231636A1

公开(公告)日：2015-08-20

申请号：US14613496

申请日：2015-02-04

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Chee Kiong Lim ,  Way Xuang LEE ,  Wuh Ken LOH ,  Chee Wee CHING ,  Chin Yong KOO ,  Siew Ying KOH ,  Tiong Han TOH ,  Kuan Moon BOO ,  Soo Yong LAU

IPC: B01L7/00 ,  B01L3/00 ,  C12Q1/68

CPC classification number: B01L7/52 ,  B01L2200/147 ,  B01L2300/0829 ,  B01L2300/1805 ,  B01L2300/1822 ,  B01L2300/1883 ,  C12Q1/6806

Abstract: In one aspect, a thermal cycler system including a sample block and a thermoelectric device is disclosed. In various embodiments, the sample block has a first surface configured to receive a plurality of reaction vessels and an opposing second surface. In various embodiments the thermoelectric device is operably coupled to the second surface of the sample block. In various embodiments a thermal control unit is provided. In various embodiments the thermal control unit includes a computer processing unit. In various embodiments the thermal control unit includes an electrical current source. In various embodiments the thermal control unit also includes an electrical interface portion configured to connect the thermoelectric device with the electrical current source by way of an electrical cable. In various embodiments the thermal control unit is oriented in a different plane than the sample block and thermoelectric cooler.

Abstract translation: 一方面，公开了一种包括样品块和热电装置的热循环仪系统。 在各种实施例中，样品块具有构造成容纳多个反应容器和相对的第二表面的第一表面。 在各种实施例中，热电装置可操作地耦合到样品块的第二表面。 在各种实施例中，提供了热控制单元。 在各种实施例中，热控制单元包括计算机处理单元。 在各种实施例中，热控制单元包括电流源。 在各种实施例中，热控制单元还包括被配置为通过电缆将热电装置与电流源连接的电接口部分。 在各种实施例中，热控制单元定向在与样品块和热电冷却器不同的平面中。

公开(公告)号：US20190126281A1

公开(公告)日：2019-05-02

申请号：US16116801

申请日：2018-08-29

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Yong CHU ,  Jeffrey MARKS ,  Jacob FREUDENTHAL ,  Mingsong CHEN ,  Tiong Han TOH ,  Mauro AGUANNO ,  Lik Seng LAU ,  Lian Seng LOH ,  Kok Siong TEO ,  Zeng Wei CHU ,  Xin MATHERS ,  Michael UY ,  Huei Steven YEO ,  Kuan Moon BOO ,  Way Xuang LEE ,  Chin Yong KOO ,  Wei Fuh TEO ,  Soo Yong LAU ,  Hon Siu SHIN ,  Zeqi TAN ,  Thomas WESSEL ,  David WOO

IPC: B01L7/00 ,  G01N21/27 ,  G01N21/64 ,  C12Q1/6806 ,  G01N35/02

Abstract: A biological analysis system is provided. The system comprises a sample block assembly. The sample block assembly comprises a sample block configured to accommodate a sample holder, the sample holder configured to receive a plurality of samples. The system also comprises a control system configured to cycle the plurality of samples through a series of temperatures. The system further comprises an automated tray comprising a slide assembly, the tray configured to reversibly slide the sample block assembly from a closed to an open position to allow user access to the plurality of sample holders.

公开(公告)号：US20180056296A1

公开(公告)日：2018-03-01

申请号：US15640241

申请日：2017-06-30

Applicant: Life Technologies Corporation

Inventor： Hon Siu SHIN ,  Chin Yong KOO ,  Way Xuang LEE ,  Chee Kiong LIM ,  Chee Wee CHING ,  Niroshan RAMACHANDRAN

IPC: B01L7/00

CPC classification number: B01L7/52 ,  B01L2200/147 ,  B01L2300/0829 ,  B01L2300/0848 ,  B01L2300/0887 ,  B01L2300/12 ,  B01L2300/1822

Abstract: A thermal block assembly including a sample block and two or more thermoelectric devices, is disclosed. The sample block has a top surface configured to receive a plurality of reaction vessels and an opposing bottom surface. The thermoelectric devices are operably coupled to the sample block, wherein each thermoelectric device includes a housing for a thermal sensor and a thermal control interface with a controller. Each thermoelectric device is further configured to operate independently from each other to provide a substantially uniform temperature profile throughout the sample block.

公开(公告)号：US20160214110A1

公开(公告)日：2016-07-28

申请号：US14917400

申请日：2014-09-15

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Hon Siu SHIN ,  Chin Yong KOO ,  Way Xuang LEE ,  Chee Kiong LIM ,  Chee Wee CHING ,  Niroshan RAMACHANDRAN

IPC: B01L7/00

CPC classification number: B01L7/52 ,  B01L2200/147 ,  B01L2300/0829 ,  B01L2300/0848 ,  B01L2300/0887 ,  B01L2300/12 ,  B01L2300/1822

Abstract: A thermal block assembly including a sample block and two or more thermoelectric devices, is disclosed. The sample block has a top surface configured to receive a plurality of reaction vessels and an opposing bottom surface. The thermoelectric devices are operably coupled to the sample block, wherein each thermoelectric device includes a housing for a thermal sensor and a thermal control interface with a controller. Each thermoelectric device is further configured to operate independently from each other to provide a substantially uniform temperature profile throughout the sample block.

Abstract translation: 公开了一种包括样品块和两个或更多个热电装置的热块组件。 样品块具有构造成容纳多个反应容器和相对的底表面的顶表面。 热电装置可操作地耦合到样品块，其中每个热电装置包括用于热传感器的壳体和具有控制器的热控制界面。 每个热电装置进一步构造成彼此独立地操作以在整个样品块中提供基本均匀的温度分布。