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    Thermal Cycler Cover
    3.
    发明申请
    Thermal Cycler Cover 审中-公开
    热循环器盖

    公开(公告)号：US20160228875A1

    公开(公告)日：2016-08-11

    申请号：US14778106

    申请日：2014-02-14

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Tiong Han Toh ,  Wuh Ken LOH ,  Kuan Moon BOO ,  Sandro David KLEIN ,  Daniel WELSH

    IPC: B01L7/00

    CPC classification number: B01L7/52 ,  B01L2300/043 ,  B01L2300/1822

    Abstract: In one aspect, a thermal cycler system is disclosed. The thermal cycler can be comprised of a device housing and a cover that is operably connected to the device housing. The cover can include a handle portion, a device lid portion, a sample block platen and a link bar. The device lid portion is attached to the proximal side of the handle portion with a pin. The sample block platen is operably connected to the handle portion such that the sample block platen is positioned against the sample block when the handle portion is flush with the device lid portion and the cover is in a closed position. The link bar is operably connected to the device housing and the pin such that a distal side of the handle portion is elevated away from the device lid portion when the cover is moved to an open position.

    Abstract translation: 一方面，公开了一种热循环仪系统。 热循环仪可以由装置壳体和可操作地连接到装置壳体的盖组成。 盖可以包括手柄部分，装置盖部分，样品块压板和连杆。 装置盖部分用销钉安装在把手部分的近侧。 样品块压板可操作地连接到手柄部分，使得当手柄部分与装置盖部分齐平并且盖处于关闭位置时，样品块压板位于样品块上。 连杆可操作地连接到装置壳体和销上，使得当盖移动到打开位置时把手部分的远端从装置盖部分升高。

    SYSTEMS AND METHODS FOR A THERMAL CYCLER HEATED COVER
    4.
    发明申请
    SYSTEMS AND METHODS FOR A THERMAL CYCLER HEATED COVER 审中-公开

    公开(公告)号：US20200016599A1

    公开(公告)日：2020-01-16

    申请号：US16515533

    申请日：2019-07-18

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Zeqi TAN ,  Wuh Ken LOH ,  Siew Yin LEE ,  Kuan Moon (Bernard) BOO

    IPC: B01L7/00 ,  G01N35/02

    Abstract: A thermal cycler system for use with a sample holder configured to receive a plurality of samples includes a sample block configured to receive the sample holder, a cover lid configured to move in a direction toward the sample block from an open position to a closed position, a heated cover operatively coupled to the cover lid and configured to move in a direction toward the sample block from a raised position to a first lowered position, in which the heated cover contacts the sample holder when the sample holder is received by the sample block, and a drive assembly including a motion guide configured to move in a direction toward the sample block from a first position, wherein the cover lid is in the open position and the heated cover is in the raised position, to a second position, wherein the cover lid is in the closed position.

    Apparatuses, Systems and Methods for Providing Scalable Thermal Cyclers and Isolating Thermoelectric Devices
    5.
    发明申请
    Apparatuses, Systems and Methods for Providing Scalable Thermal Cyclers and Isolating Thermoelectric Devices 审中-公开
    用于提供可扩展热循环器和隔离热电器件的设备，系统和方法

    公开(公告)号：US20150231636A1

    公开(公告)日：2015-08-20

    申请号：US14613496

    申请日：2015-02-04

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Chee Kiong Lim ,  Way Xuang LEE ,  Wuh Ken LOH ,  Chee Wee CHING ,  Chin Yong KOO ,  Siew Ying KOH ,  Tiong Han TOH ,  Kuan Moon BOO ,  Soo Yong LAU

    IPC: B01L7/00 ,  B01L3/00 ,  C12Q1/68

    CPC classification number: B01L7/52 ,  B01L2200/147 ,  B01L2300/0829 ,  B01L2300/1805 ,  B01L2300/1822 ,  B01L2300/1883 ,  C12Q1/6806

    Abstract: In one aspect, a thermal cycler system including a sample block and a thermoelectric device is disclosed. In various embodiments, the sample block has a first surface configured to receive a plurality of reaction vessels and an opposing second surface. In various embodiments the thermoelectric device is operably coupled to the second surface of the sample block. In various embodiments a thermal control unit is provided. In various embodiments the thermal control unit includes a computer processing unit. In various embodiments the thermal control unit includes an electrical current source. In various embodiments the thermal control unit also includes an electrical interface portion configured to connect the thermoelectric device with the electrical current source by way of an electrical cable. In various embodiments the thermal control unit is oriented in a different plane than the sample block and thermoelectric cooler.

    Abstract translation: 一方面，公开了一种包括样品块和热电装置的热循环仪系统。 在各种实施例中，样品块具有构造成容纳多个反应容器和相对的第二表面的第一表面。 在各种实施例中，热电装置可操作地耦合到样品块的第二表面。 在各种实施例中，提供了热控制单元。 在各种实施例中，热控制单元包括计算机处理单元。 在各种实施例中，热控制单元包括电流源。 在各种实施例中，热控制单元还包括被配置为通过电缆将热电装置与电流源连接的电接口部分。 在各种实施例中，热控制单元定向在与样品块和热电冷却器不同的平面中。

    THERMAL CYCLER SYSTEMS AND METHODS OF USE
    6.
    发明申请
    THERMAL CYCLER SYSTEMS AND METHODS OF USE 有权

    公开(公告)号：US20230134044A1

    公开(公告)日：2023-05-04

    申请号：US18148139

    申请日：2022-12-29

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Zeqi TAN ,  Wuh Ken LOH ,  Siew Yin LEE ,  Kuan Moon (Bernard) BOO

    IPC: B01L7/00 ,  B01L9/00

    Abstract: A thermal cycler system comprises a sample block configured to receive a sample holder configured to receive a plurality of samples; an adaptor configured to surround a periphery of the sample block; and a drip pan configured to surround a periphery of the adaptor. The drip pan comprises one or more ejector mechanisms and one or more openings, the one or more ejector mechanisms configured to respectively extend through the one or more openings into contact with the sample holder in a state of the sample holder received by the sample block and the adaptor surrounding the periphery of the sample block.

    BIOLOGICAL ANALYSIS DEVICES AND SYSTEMS
    9.
    发明申请
    BIOLOGICAL ANALYSIS DEVICES AND SYSTEMS 有权

    公开(公告)号：US20220205915A1

    公开(公告)日：2022-06-30

    申请号：US17572926

    申请日：2022-01-11

    Applicant: LIFE TECHNOLOGIES HOLDINGS PTE LIMITED ,  LIFE TECHNOLOGIES CORPORATION

    Inventor： Ming Song CHEN ,  Chee Woei CHONG ,  Wuh Ken LOH ,  WERN YUH FOO ,  Kuan Moon BOO ,  Norbert LECLERC ,  Kristina UHLENDORF ,  Reiner KOELLNER ,  Torsten FUCHS ,  Stefan BREITFELDER

    IPC: G01N21/64

    Abstract: A biological analysis system can include an excitation module and an emission module. The excitation module can include a collimator element for receiving excitation light from the excitation light source and transmitting collimated excitation light in a first direction, and a plurality of excitation mirrors arrayed along the excitation light path, each excitation mirror disposed at an acute angle relative to the first direction and configured to reflect collimated excitation light along a second direction. The emission module can be positioned to receive excitation light transmitted along the second direction and can include a sample block comprising a plurality of sample receptacles positioned to receive a beam of collimated excitation light, and a plurality of photodetectors configured to receive emission light transmitted from a respective sample receptacle in a direction transverse to the second direction of the excitation light path.

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