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公开(公告)号：US20180169216A1
公开(公告)日：2018-06-21
申请号：US15888718
申请日：2018-02-05
Applicant: Merial Inc.
IPC: A61K39/135 , A61K39/385 , C07K14/005 , C07K14/32 , C12N7/00 , A61K39/00
CPC classification number: A61K39/135 , A61K39/385 , A61K2039/5258 , A61K2039/545 , A61K2039/552 , A61K2039/55566 , A61K2039/6075 , C07K14/005 , C07K14/32 , C07K2319/40 , C07K2319/735 , C12N7/00 , C12N2770/24222 , C12N2770/32122 , C12N2770/32134 , C12N2770/32171
Abstract: The present invention encompasses FMDV vaccines or compositions. The vaccine or composition may be a vaccine or composition containing FMDV antigens. The invention also encompasses recombinant vectors encoding and expressing FMDV antigens, epitopes or immunogens which can be used to protect animals, in particular ovines, bovines, caprines, or swines, against FMDV. The invention further encompasses methods of making or producing antigenic polypeptides or antigens.
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公开(公告)号：US20170143819A1
公开(公告)日：2017-05-25
申请号：US15353727
申请日：2016-11-16
Applicant: MERIAL INC.
IPC: A61K39/135 , C07K14/005 , C12N7/00 , A61K39/385
CPC classification number: A61K39/135 , A61K39/385 , A61K2039/5258 , A61K2039/545 , A61K2039/552 , A61K2039/55566 , A61K2039/6075 , C07K14/005 , C07K14/32 , C07K2319/40 , C07K2319/735 , C12N7/00 , C12N2770/24222 , C12N2770/32122 , C12N2770/32134 , C12N2770/32171
Abstract: The present invention encompasses FMDV vaccines or compositions. The vaccine or composition may be a vaccine or composition containing FMDV antigens. The invention also encompasses recombinant vectors encoding and expressing FMDV antigens, epitopes or immunogens which can be used to protect animals, in particular ovines, bovines, caprines, or swines, against FMDV. The invention further encompasses methods of making or producing antigenic polypeptides or antigens.
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公开(公告)号：US20170087242A1
公开(公告)日：2017-03-30
申请号：US15233013
申请日：2016-08-10
Applicant: MERIAL, INC.
IPC: A61K39/155 , C12N7/00
CPC classification number: A61K39/155 , A61K39/12 , A61K2039/505 , A61K2039/5254 , A61K2039/5256 , A61K2039/53 , A61K2039/545 , A61K2039/70 , C07K14/005 , C12N7/00 , C12N2710/24043 , C12N2760/18222 , C12N2760/18234 , C12N2799/023
Abstract: The present invention provides vectors that contain and express in vivo or in vitro one or more Hendra virus polypeptides or antigens that elicit an immune response in animal or human against Hendra virus and Nipah virus, compositions comprising said vectors and/or Hendra virus polypeptides, methods of vaccination against Hendra virus and Nipah virus, and kits for use with such methods and compositions.
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公开(公告)号：US10076566B2
公开(公告)日：2018-09-18
申请号：US15084108
申请日：2016-03-29
Applicant: MERIAL, INC.
Inventor： Jean-Christophe Audonnet , Jules Minke
IPC: A61K39/175 , C12N7/00 , A61K39/12 , C07K14/005 , C07K14/535 , A61N5/06 , A61K39/00
CPC classification number: A61K39/175 , A61K39/12 , A61K2039/53 , A61K2039/545 , A61K2039/552 , A61K2039/55522 , A61N5/0613 , C07K14/005 , C07K14/535 , C12N7/00 , C12N2710/24043 , C12N2750/14334 , C12N2760/18422 , C12N2760/18434 , C12N2760/18471 , C12N2800/22
Abstract: The present invention provides vectors that contain and express in vivo or in vitro CDV polypeptides or antigens that elicit an immune response in animal against CDV, compositions comprising said vectors and/or CDV polypeptides, and methods of vaccination against CDV. The invention further provides methods for inducing an immunogenic or protective response against CDV and other canine virus, as well as methods for preventing or treating CDV and other canine virus or disease state(s) caused by CDV and other canine virus.
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公开(公告)号：US20180236056A1
公开(公告)日：2018-08-23
申请号：US15499072
申请日：2017-04-27
Applicant: MERIAL INC. , CHULALONGKORN UNIVERSITY
Inventor： Sanipa Suradhat , Jean-Christophe Audonnet , Catherine Charreyre
CPC classification number: A61K39/12 , A61K2039/53 , A61K2039/54 , A61K2039/552 , C12N2770/10034
Abstract: The invention provides novel methods and compositions for the vaccination of porcine animals against porcine reproductive and respiratory syndrome virus (PRRSV). Described herein are immunological and/or vaccine compositions comprising a DNA vector encoding a PRRSV protein, particularly a truncated ORF7 protein, which are administered to porcines using needle-free delivery. The plasmid can include more than one nucleic acid molecule such that the plasmid can express more than one antigen. Also disclosed are methods for using and kits employing such compositions.
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Patent Agency Ranking
公开(公告)号：US09913891B2
公开(公告)日：2018-03-13
申请号：US15353727
申请日：2016-11-16
Applicant: MERIAL INC.
IPC: A61K48/00 , C12N15/85 , A61K38/19 , C07K14/535 , A61K38/18 , A61K39/135 , A61K39/385 , C07K14/005 , C12N7/00 , C07K14/32 , A61K39/00
CPC classification number: A61K39/135 , A61K39/385 , A61K2039/5258 , A61K2039/545 , A61K2039/552 , A61K2039/55566 , A61K2039/6075 , C07K14/005 , C07K14/32 , C07K2319/40 , C07K2319/735 , C12N7/00 , C12N2770/24222 , C12N2770/32122 , C12N2770/32134 , C12N2770/32171
Abstract: The present invention encompasses FMDV vaccines or compositions. The vaccine or composition may be a vaccine or composition containing FMDV antigens. The invention also encompasses recombinant vectors encoding and expressing FMDV antigens, epitopes or immunogens which can be used to protect animals, in particular ovines, bovines, caprines, or swines, against FMDV. The invention further encompasses methods of making or producing antigenic polypeptides or antigens.
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公开(公告)号：US20170022255A1
公开(公告)日：2017-01-26
申请号：US15098350
申请日：2016-04-14
Applicant: MERIAL, INC.
Inventor： Jean-Christophe Audonnet , Xuan Guo , Kevin Cox
IPC: C07K14/005 , C12N15/82
CPC classification number: C07K14/005 , A61K39/12 , A61K39/15 , A61K2039/517 , A61K2039/5252 , A61K2039/552 , A61K2039/55505 , A61K2039/55561 , A61K2039/55566 , A61K2039/55577 , C12N15/8258 , C12N2720/12134
Abstract: The present invention encompasses BTV vaccines or compositions. The vaccine or composition may be a vaccine or composition containing BTV antigens. The invention also encompasses recombinant vectors encoding and expressing BTV antigens, epitopes or immunogens which can be used to protect animals, such as ovines, bovines, or caprines, against BTV.
Abstract translation: 本发明包括BTV疫苗或组合物。 疫苗或组合物可以是含有BTV抗原的疫苗或组合物。 本发明还包括编码和表达BTV抗原，表位或免疫原的重组载体，其可用于保护动物，例如绵羊，牛，或者对于BTV的动物。
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公开(公告)号：US20160220659A1
公开(公告)日：2016-08-04
申请号：US14863181
申请日：2015-09-23
Applicant: MERIAL, INC.
Inventor： Jean-Christophe Audonnet , Zahia Hannas-Djebbara , Teshome Mebatsion , Yu-Wei Chiang , Justin Widener , Frédéric Reynard
IPC: A61K39/135 , C07K14/005 , C12N7/00
CPC classification number: A61K39/135 , A61K39/12 , A61K2039/5258 , A61K2039/545 , A61K2039/55577 , C07K14/005 , C12N7/00 , C12N2710/10043 , C12N2710/14043 , C12N2770/32123 , C12N2770/32134
Abstract: The present invention encompasses FMDV vaccines or compositions. The vaccine or composition may be a vaccine or composition containing FMDV antigens. The invention also encompasses recombinant vectors encoding and expressing FMDV antigens, epitopes or immunogens which can be used to protect animals, in particular ovines, bovines, caprines, or swines, against FMDV.
Abstract translation: 本发明包括FMDV疫苗或组合物。 疫苗或组合物可以是含有FMDV抗原的疫苗或组合物。 本发明还包括编码和表达FMDV抗原，表位或免疫原的重组载体，其可用于保护动物，特别是针对FMDV的动物，特别是羊，牛，cap或猪。
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公开(公告)号：US20160199483A1
公开(公告)日：2016-07-14
申请号：US15084108
申请日：2016-03-29
Applicant: MERIAL, INC.
Inventor： Jean-Christophe Audonnet , Jules Minke
IPC: A61K39/175 , C07K14/535 , C12N7/00 , C07K14/005
CPC classification number: A61K39/175 , A61K39/12 , A61K2039/53 , A61K2039/545 , A61K2039/552 , A61K2039/55522 , A61N5/0613 , C07K14/005 , C07K14/535 , C12N7/00 , C12N2710/24043 , C12N2750/14334 , C12N2760/18422 , C12N2760/18434 , C12N2760/18471 , C12N2800/22
Abstract: The present invention provides vectors that contain and express in vivo or in vitro CDV polypeptides or antigens that elicit an immune response in animal against CDV, compositions comprising said vectors and/or CDV polypeptides, and methods of vaccination against CDV. The invention further provides methods for inducing an immunogenic or protective response against CDV and other canine virus, as well as methods for preventing or treating CDV and other canine virus or disease state(s) caused by CDV and other canine virus.
Abstract translation: 本发明提供载体，其含有体内或体外CDV多肽或在动物体内产生针对CDV的免疫应答的抗原，包含所述载体和/或CDV多肽的组合物，以及针对CDV的疫苗接种方法。 本发明还提供了诱导针对CDV和其他犬病毒的免疫原性或保护性应答的方法，以及用于预防或治疗CDV和其他犬病毒或由CDV和其他犬病毒引起的疾病状态的方法。
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公开(公告)号：US10010605B2
公开(公告)日：2018-07-03
申请号：US14863181
申请日：2015-09-23
Applicant: MERIAL, INC.
Inventor： Jean-Christophe Audonnet , Zahia Hannas-Djebbara , Teshome Mebatsion , Yu-Wei Chiang , Justin Widener , Frédéric Reynard
IPC: A61K39/135 , A61K39/12 , C07K14/005 , C12N7/00 , A61K39/00
CPC classification number: A61K39/135 , A61K39/12 , A61K2039/5258 , A61K2039/545 , A61K2039/55577 , C07K14/005 , C12N7/00 , C12N2710/10043 , C12N2710/14043 , C12N2770/32123 , C12N2770/32134
Abstract: The present invention encompasses FMDV vaccines or compositions. The vaccine or composition may be a vaccine or composition containing FMDV antigens. The invention also encompasses recombinant vectors encoding and expressing FMDV antigens, epitopes or immunogens which can be used to protect animals, in particular ovines, bovines, caprines, or swines, against FMDV.
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