公开(公告)号：US09423475B2

公开(公告)日：2016-08-23

申请号：US13799588

申请日：2013-03-13

Applicant: MRI Interventions, Inc.

Inventor： Parag Karmarkar ,  Rajesh Pandey

IPC: G01R33/28 ,  A61B18/14 ,  A61B17/00 ,  A61B18/00

CPC classification number: G01R33/287 ,  A61B18/1492 ,  A61B2017/00039 ,  A61B2018/00773 ,  A61B2018/00815 ,  A61B2034/2051

Abstract: An elongate electrical lead assembly that reduces localized heating due to MR scanner-induced currents includes a first elongate electrical lead having a series of alternating single layer coil sections and multi-layer coil sections, a second elongate electrical lead having a series of alternating single layer coil sections and multi-layer coil sections, and a third elongate electrical lead having a coiled section that coaxially surrounds the first and second electrical leads. Each multi-layer coil section of the second electrical lead is coiled around a respective single layer coil section of the first electrical lead, and each single layer coil section of the second electrical lead is coiled around a respective multi-layer coil section of the first electrical lead.

Abstract translation: 由MR扫描器感应的电流减少局部加热的细长电引线组件包括具有一系列交替的单层线圈部分和多层线圈部分的第一细长电引线，具有一系列交替单层 线圈段和多层线圈段，以及具有同轴地围绕第一和第二电引线的螺旋段的第三细长电引线。 第二电引线的每个多层线圈部分围绕第一电引线的相应单层线圈部分卷绕，并且第二电引线的每个单层线圈部分围绕第一电引线的相应多层线圈部分卷绕 电铅。

公开(公告)号：US10357281B2

公开(公告)日：2019-07-23

申请号：US14829708

申请日：2015-08-19

Applicant: MRI Interventions, Inc.

Inventor： Peter Piferi ,  Jesse Flores ,  Rajesh Pandey

IPC: A61B17/34 ,  A61B17/00 ,  A61B90/11 ,  A61B34/20 ,  A61N1/05 ,  A61B90/10

Abstract: Surgical devices such as a device guide for a trajectory frame for image-guided procedures, is configured with first and second elongate and cooperating semi-circular members that together define a longitudinally extending open channel and that can separate along longitudinally extending split lines into discrete first and second elongate semicircular members. The surgical devices with the first and second semi-circular members can include a device guide and dock and lock inserts that are detachably held by dock and lock members to a guide support column that also concurrently holds the device guide during at least part of an image guided procedure.

公开(公告)号：US20180303560A1

公开(公告)日：2018-10-25

申请号：US15934165

申请日：2018-03-23

Applicant: MRI Interventions, Inc.

Inventor： Rajesh Pandey ,  Maxwell Jerad Daly ,  Peter G. Piferi

IPC: A61B34/20 ,  A61B5/055 ,  A61B90/11

CPC classification number: A61B34/20 ,  A61B5/055 ,  A61B17/1703 ,  A61B17/3462 ,  A61B90/11 ,  A61B2017/00477 ,  A61B2017/3407 ,  A61B2017/3492 ,  A61B2034/2046 ,  A61B2034/2074

Abstract: A trajectory frame/guide assembly for use with surgical navigation systems includes a base having a patient access aperture formed therein. A yoke is mounted to the base and is rotatable about a roll axis. A platform is mounted to the yoke and is rotatable about a pitch axis and interchangeably holds a single lumen or multi-lumen guide array and a device guide. No x-y actuators are required and a virtual guide array may also or alternatively be used to identify a desired open channel in the device guide for the preferred trajectory path.

公开(公告)号：US20160256233A1

公开(公告)日：2016-09-08

申请号：US15046713

申请日：2016-02-18

Applicant: MRI Interventions, Inc.

Inventor： Rajesh Pandey ,  Maxwell Jerad Daly

IPC: A61B90/11 ,  A61B5/055

CPC classification number: A61B90/11 ,  A61B5/055 ,  A61B5/064 ,  A61B5/743 ,  A61B2017/00862 ,  A61B2090/103

Abstract: A trajectory guide frame for use with an image-guided interventional system includes a base, an elongate device guide support, a device guide, and a locking device. The base has a patient access aperture formed therein. The elongate device guide support is secured to the base and has opposite proximal and distal ends. The distal end is positioned proximate the patient access aperture. The device guide support includes a device guide support bore therethrough that extends from the proximal end to the distal end. The device guide is configured to be removably inserted in the device guide support bore. The device guide includes a device guide lumen configured to removably receive an interventional device therethrough. The locking device is configured to secure the interventional device to the device guide and/or the device guide support. The locking device includes a gripping mechanism including: a compression gripping member defining a gripping member bore to receive the interventional device therethrough; and a loading mechanism operable to deform the compression gripping member to grip the interventional device extending through the gripping member bore.

Abstract translation: 用于与图像引导的介入系统一起使用的轨迹引导框架包括底座，细长装置引导支撑件，装置引导件和锁定装置。 基部具有形成在其中的患者进入孔。 细长装置引导支撑件固定到基座并且具有相对的近端和远端。 远端位于病人进入孔附近。 装置引导支撑件包括穿过其中的从近端延伸到远端的装置引导件支撑孔。 装置引导件构造成可拆卸地插入装置引导支撑孔中。 装置引导件包括被配置为可移除地接收通过其的介入装置的装置引导腔。 锁定装置被配置为将介入装置固定到装置引导件和/或装置引导件支撑件。 锁定装置包括夹持机构，其包括：压缩夹持构件，其限定夹持构件孔，以通过其夹持介入装置; 以及可操作以使压缩夹持构件变形以夹持延伸穿过夹持构件孔的介入装置的装载机构。

公开(公告)号：US20140066750A1

公开(公告)日：2014-03-06

申请号：US13801190

申请日：2013-03-13

Applicant: MRI INTERVENTIONS, INC.

Inventor： Peter Piferi ,  Daniele Ghidoli ,  Rajesh Pandey ,  Jesse Flores

IPC: A61B19/00 ,  A61B5/055

CPC classification number: A61B19/201 ,  A61B5/055 ,  A61B90/11 ,  A61B2017/00911 ,  A61B2017/3407 ,  A61B2090/3954

Abstract: An MRI-guided interventional system for use with a patient and an interventional device includes a base, a trajectory guide frame, and a mounting device. The base is configured to be secured to a body of the patient. The trajectory guide frame includes a targeting cannula. The targeting cannula has an elongate guide bore extending axially therethrough, defining a trajectory axis, and being configured to guide placement of the interventional device. The trajectory guide frame is operable to move the targeting cannula relative to the base to position the trajectory axis to a desired intrabody trajectory to guide placement of the interventional device in vivo. A plurality of patient engagement structures are provided on the base and are configured to penetrate tissue of the body and to space the base apart from the tissue. The system further includes a plurality of fasteners configured to secure the base to the body.

Abstract translation: 用于患者和介入装置的MRI引导介入系统包括基座，轨迹引导框架和安装装置。 基座构造成固定到患者的身体。 轨迹引导框架包括靶向插管。 靶向套管具有轴向延伸穿过其中的细长导向孔，其限定轨迹轴线，并且被配置为引导介入装置的放置。 轨迹引导框架可操作以相对于底座移动目标套管，以将轨迹轴定位到期望的体内轨迹，以引导介入装置在体内的放置。 多个患者接合结构设置在基座上并被构造成穿透身体的组织并且使基部与组织分开。 该系统还包括多个紧固件，其被配置成将基座固定到主体上。

公开(公告)号：US10307220B2

公开(公告)日：2019-06-04

申请号：US15250590

申请日：2016-08-29

Applicant: MRI Interventions, Inc.

Inventor： Peter Piferi ,  Rajesh Pandey ,  Maxwell Jerad Daly ,  Kimble L. Jenkins

IPC: A61B90/11 ,  A61N1/05 ,  A61B17/17 ,  A61B17/16 ,  A61M25/02 ,  A61B17/00 ,  A61B6/03 ,  G01R33/28 ,  G01R33/48 ,  G01R33/565 ,  A61B6/00 ,  A61B5/055 ,  A61N1/372 ,  A61B90/00 ,  A61B34/20 ,  A61B90/10

Abstract: A trajectory frame for use with surgical navigation systems includes a base having a patient access aperture formed therein. A yoke is mounted to the base and is rotatable about a roll axis. A platform is mounted to the yoke and is rotatable about a pitch axis. An elongated guide is secured to the platform and includes opposite proximal and distal end portions and a bore that extends from the proximal end portion to the distal end portion. The guide is configured to removably receive various devices therein for quick release therefrom, including an optical tracking probe (which may be a universal tracker) detectable by a camera-based tracking system or an EM probe detectable by an EM navigation system, a microelectrode probe driver adapter, a drill guide and drill bit, skull fixation device and driver, and a catheter guide.

公开(公告)号：USD824027S1

公开(公告)日：2018-07-24

申请号：US29551396

申请日：2016-01-13

Applicant: MRI Interventions, Inc.

Designer： Jesse Flores ,  Rajesh Pandey ,  Maxwell Jerad Daly

公开(公告)号：US09498290B2

公开(公告)日：2016-11-22

申请号：US14515105

申请日：2014-10-15

Applicant: MRI Interventions, Inc.

Inventor： Peter Piferi ,  Rajesh Pandey ,  Maxwell Jerad Daly ,  Kimble L. Jenkins

IPC: A61B19/00 ,  A61N1/05 ,  A61B17/17 ,  A61B17/16 ,  A61M25/02 ,  A61B17/00 ,  A61B6/03 ,  G01R33/28 ,  G01R33/48 ,  G01R33/565 ,  A61B6/00 ,  A61B5/055

CPC classification number: A61B90/11 ,  A61B5/055 ,  A61B6/032 ,  A61B6/5258 ,  A61B17/00234 ,  A61B17/1615 ,  A61B17/1695 ,  A61B17/1703 ,  A61B17/1739 ,  A61B2034/2051 ,  A61B2034/2055 ,  A61B2090/103 ,  A61B2090/3983 ,  A61M25/02 ,  A61M2025/028 ,  A61M2210/0687 ,  A61M2210/0693 ,  A61N1/0534 ,  A61N1/372 ,  G01R33/286 ,  G01R33/4812 ,  G01R33/565

Abstract: A trajectory frame for use with surgical navigation systems includes a base having a patient access aperture formed therein. A yoke is mounted to the base and is rotatable about a roll axis. A platform is mounted to the yoke and is rotatable about a pitch axis. An elongated guide is secured to the platform and includes opposite proximal and distal end portions and a bore that extends from the proximal end portion to the distal end portion. The guide is configured to removably receive various devices therein for quick release therefrom, including an optical tracking probe (which may be a universal tracker) detectable by a camera-based tracking system or an EM probe detectable by an EM navigation system, a microelectrode probe driver adapter, a drill guide and drill bit, skull fixation device and driver, and a catheter guide.

Abstract translation: 与外科导航系统一起使用的轨迹框架包括其中形成有患者进入孔的底座。 轭架安装在基座上并可围绕辊轴线旋转。 平台安装在轭架上并可绕俯仰轴线旋转。 细长的导向件固定到平台上并且包括相对的近端部分和远端部分以及从近端部分延伸到远端部分的孔。 引导件被构造成可移除地接收其中的各种装置以从其中快速释放，包括可由基于照相机的跟踪系统或可由EM导航系统检测的EM探针可检测的光学跟踪探针（其可以是通用跟踪器），微电极探针 驱动器适配器，钻子引导器和钻头，头骨固定装置和驱动器以及导管引导件。

公开(公告)号：US20130131496A1

公开(公告)日：2013-05-23

申请号：US13749351

申请日：2013-01-24

Applicant: MRI Interventions, Inc.

Inventor： Kimble L. Jenkins ,  Peter Piferi ,  Kamal Vij ,  Daniele Ghidoli ,  Jesse Flores ,  Parag V. Karmarkar ,  Rajesh Pandey

IPC: A61B5/06 ,  A61B5/00 ,  A61B5/053 ,  A61B18/02 ,  A61M25/01 ,  A61M5/00 ,  A61B5/055 ,  A61B18/18

CPC classification number: A61B5/062 ,  A61B5/0044 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/053 ,  A61B5/055 ,  A61B5/065 ,  A61B5/415 ,  A61B5/418 ,  A61B18/02 ,  A61B18/18 ,  A61B34/10 ,  A61B34/20 ,  A61B2090/365 ,  A61B2090/374 ,  A61B2090/3954 ,  A61M5/00 ,  A61M25/01 ,  A61M25/0127 ,  A61M29/00 ,  A61M2025/0089 ,  A61M2025/0166 ,  A61M2025/0681 ,  A61M2025/09175 ,  G01R33/286 ,  G01R33/287

Abstract: An MRI-compatible catheter that reduces localized heating due to MR scanner-induced currents includes an elongated flexible shaft having a distal end portion and an opposite proximal end portion. A handle is attached to the proximal end portion and includes an electrical connector interface configured to be in electrical communication with an MRI scanner. One or more RF tracking coils are positioned adjacent the distal end portion of the shaft. Each RF tracking coil includes a conductive lead, such as a coaxial cable, that extends between the RF tracking coil and the electrical connector interface and electrically connects the RF tracking coil to an MRI scanner. In some embodiments of the present invention, the conductive lead has a length sufficient to define an odd harmonic/multiple of a quarter wavelength of the operational frequency of the MRI Scanner, and/or includes a series of pre-formed back and forth segments along its length.

Abstract translation: 减少由于MR扫描器感应电流引起的局部加热的MRI兼容导管包括具有远端部分和相对近端部分的细长柔性轴。 手柄附接到近端部分并且包括被配置为与MRI扫描仪电连通的电连接器接口。 一个或多个RF跟踪线圈定位在轴的远端部分附近。 每个RF跟踪线圈包括在RF跟踪线圈和电连接器接口之间延伸的导电引线，例如同轴电缆，并将RF跟踪线圈电连接到MRI扫描器。 在本发明的一些实施例中，导电引线具有足以限定MRI扫描器的工作频率的四分之一波长的奇次谐波/倍数的长度，和/或包括一系列预先形成的前后段 它的长度。

公开(公告)号：US10596353B2

公开(公告)日：2020-03-24

申请号：US15294013

申请日：2016-10-14

Applicant: MRI Interventions, Inc.

Inventor： Jesse Flores ,  Rajesh Pandey ,  Peter Piferi ,  Kamal Vij

IPC: A61M25/09

Abstract: A passive MRI-compatible guidewire includes an elongate, flexible tubular shaft, an elongate core wire of non-ferromagnetic material, and an elongate spring coil of non-ferromagnetic material axially surrounding the elongate core wire to form a distal end portion. The core wire includes opposite first and second end portions separated by an intermediate portion. The intermediate portion has a round cross-section, and the first and second end portions each have a non-round cross-section. The first end portion of the core wire resides within an inner lumen of the tubular shaft and is secured therewithin. The spring coil includes opposite first and second ends, and the spring coil second end is secured to the core wire second end portion via polymeric material that forms a rounded distal tip of the guidewire. The guidewire includes a plurality of spaced-apart, passive MRI-visible markers.