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    Medical probes for creating and diagnosing circumferential lesions within or around the ostium of a vessel
    1.
    发明授权
    Medical probes for creating and diagnosing circumferential lesions within or around the ostium of a vessel 有权
    用于创建和诊断血管口内或周围周围损伤的医用探针

    公开(公告)号：US07435248B2

    公开(公告)日：2008-10-14

    申请号：US10672457

    申请日：2003-09-26

    申请人： Miriam H. Taimisto ,  Josef V. Koblish

    发明人： Miriam H. Taimisto ,  Josef V. Koblish

    IPC分类号： A61B18/14 ,  A61B5/042

    CPC分类号： A61B18/1492 ,  A61B2017/00044 ,  A61B2017/00243 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00375 ,  A61B2018/00839 ,  A61B2018/1435

    摘要： The present inventions provide assemblies, probes, and methods for creating circumferential lesions in tissue, e.g., the tissue within or around the ostium of a vessel. An ablation probe with an ablative structure can be placed in contact within or around the ostium of the vessel. A diagnostic probe can be introduced through a lumen within the ablation probe and inserted into the vessel. The energy can be provided to the ablative structure to create a circumferential lesion within or around the ostium of the vessel, and the diagnostic structure can be used to diagnose the tissue to determine whether the circumferential lesion can be properly created.

    摘要翻译： 本发明提供用于在组织中产生周向损伤的组件，探针和方法，例如在血管的口内或周围的组织。 具有烧蚀结构的消融探针可以在容器的口中或周围接触放置。 诊断探针可以通过消融探针中的内腔引入并插入血管。 可以将能量提供给烧蚀结构以在容器的口内或周围形成周缘损伤，并且诊断结构可用于诊断组织以确定是否可以适当地产生周缘损伤。

    Medical probes for creating and diagnosing circumferential lesions within or around the ostium of a vessel
    2.
    发明授权
    Medical probes for creating and diagnosing circumferential lesions within or around the ostium of a vessel 有权
    用于创建和诊断血管口内或周围周围损伤的医用探针

    公开(公告)号：US07959630B2

    公开(公告)日：2011-06-14

    申请号：US12209124

    申请日：2008-09-11

    申请人： Miriam H. Taimisto ,  Josef V. Koblish

    发明人： Miriam H. Taimisto ,  Josef V. Koblish

    IPC分类号： A61B18/14 ,  A61B5/042

    CPC分类号： A61B18/1492 ,  A61B2017/00044 ,  A61B2017/00243 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00375 ,  A61B2018/00839 ,  A61B2018/1435

    摘要： The present inventions provide assemblies, probes, and methods for creating circumferential lesions in tissue, e.g., the tissue within or around the ostium of a vessel. An ablation probe with an ablative structure can be placed in contact within or around the ostium of the vessel. A diagnostic probe can be introduced through a lumen within the ablation probe and inserted into the vessel. The energy can be provided to the ablative structure to create a circumferential lesion within or around the ostium of the vessel, and the diagnostic structure can be used to diagnose the tissue to determine whether the circumferential lesion can be properly created.

    摘要翻译： 本发明提供用于在组织中产生周向损伤的组件，探针和方法，例如在血管的口内或周围的组织。 具有烧蚀结构的消融探针可以在容器的口中或周围接触放置。 诊断探针可以通过消融探针中的内腔引入并插入血管。 可以将能量提供给烧蚀结构以在容器的口内或周围形成周缘损伤，并且诊断结构可用于诊断组织以确定是否可以适当地产生周缘损伤。

    MEDICAL PROBES FOR CREATING AND DIAGNOSING CIRCUMFERENTIAL LESIONS WITHIN OR AROUND THE OSTIUM OF A VESSEL
    3.
    发明申请
    MEDICAL PROBES FOR CREATING AND DIAGNOSING CIRCUMFERENTIAL LESIONS WITHIN OR AROUND THE OSTIUM OF A VESSEL 有权
    用于创建和诊断血管内皮细胞或其周围的周围淋巴结的医学探针

    公开(公告)号：US20090018534A1

    公开(公告)日：2009-01-15

    申请号：US12209124

    申请日：2008-09-11

    申请人： Miriam H. Taimisto ,  Josef V. Koblish

    发明人： Miriam H. Taimisto ,  Josef V. Koblish

    IPC分类号： A61B18/18

    CPC分类号： A61B18/1492 ,  A61B2017/00044 ,  A61B2017/00243 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00375 ,  A61B2018/00839 ,  A61B2018/1435

    摘要： The present inventions provide assemblies, probes, and methods for creating circumferential lesions in tissue, e.g., the tissue within or around the ostium of a vessel. An ablation probe with an ablative structure can be placed in contact within or around the ostium of the vessel. A diagnostic probe can be introduced through a lumen within the ablation probe and inserted into the vessel. The energy can be provided to the ablative structure to create a circumferential lesion within or around the ostium of the vessel, and the diagnostic structure can be used to diagnose the tissue to determine whether the circumferential lesion can be properly created.

    摘要翻译： 本发明提供用于在组织中产生周向损伤的组件，探针和方法，例如在血管的口内或周围的组织。 具有烧蚀结构的消融探针可以在容器的口中或周围接触放置。 诊断探针可以通过消融探针中的内腔引入并插入血管。 可以将能量提供给烧蚀结构以在容器的口内或周围形成周缘损伤，并且诊断结构可用于诊断组织以确定是否可以适当地产生周缘损伤。

    APPARATUS AND METHODS FOR CRYOGENICALLY ABLATING TISSUE AND ADJUSTING CRYOGENIC ABLATION REGIONS
    6.
    发明申请
    APPARATUS AND METHODS FOR CRYOGENICALLY ABLATING TISSUE AND ADJUSTING CRYOGENIC ABLATION REGIONS 有权
    冷冻组织和调节低温消退区的装置和方法

    公开(公告)号：US20090287202A1

    公开(公告)日：2009-11-19

    申请号：US12432538

    申请日：2009-04-29

    申请人： Frank W. Ingle ,  Robert F. Bencini ,  Josef V. Koblish ,  Jonathan A. Wohlgemuth ,  Paul Roche

    发明人： Frank W. Ingle ,  Robert F. Bencini ,  Josef V. Koblish ,  Jonathan A. Wohlgemuth ,  Paul Roche

    IPC分类号： A61B18/02

    CPC分类号： A61B18/02 ,  A61B2017/22051 ,  A61B2017/22054 ,  A61B2018/00196 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61M25/1011

    摘要： Apparatus and methods for performing cryogenic ablation of tissue and adjusting the size and/or location of a cryogenic cooling region. A cooling assembly may include tubes for dispensing and exhausting a coolant or refrigerant. One or both of the tubes may be moved, e.g., slidably adjusted, in order to adjust the location or size of a cryogenic ablation region. The cooling assembly may be integrated into cryogenic ablation devices including a cryogenic balloon device that includes an inner inflatable balloon and another balloon that is at least partially wrapped around the inner balloon and carries refrigerant for performing cryo-ablation. Electrodes permit electrical mapping of tissue before or after cryo-ablation to verify success of the procedure.

    摘要翻译： 用于对组织进行低温消融并调节低温冷却区域的尺寸和/或位置的装置和方法。 冷却组件可以包括用于分配和排出冷却剂或制冷剂的管。 一个或两个管可以被移动，例如可滑动地调节，以便调节低温消融区域的位置或尺寸。 冷却组件可以集成到低温消融装置中，包括低温球囊装置，其包括内部可充气球囊和至少部分地缠绕在内球囊周围并承载用于进行低温消融的制冷剂的另一球囊。 电极允许在低温消融之前或之后对组织进行电气测绘，以验证该程序的成功。

    Deflectable catheter for ablating cardiac tissue
    10.
    发明授权
    Deflectable catheter for ablating cardiac tissue 失效
    用于消融心脏组织的可挠性导管

    公开(公告)号：US6083222A

    公开(公告)日：2000-07-04

    申请号：US730896

    申请日：1996-10-18

    申请人： George J. Klein ,  Josef V. Koblish ,  Thomas T. Coen

    发明人： George J. Klein ,  Josef V. Koblish ,  Thomas T. Coen

    IPC分类号： A61B10/00 ,  A61B10/06 ,  A61B17/00 ,  A61B18/00 ,  A61B18/14 ,  A61N1/05 ,  A61B17/39 ,  A61B5/0402

    CPC分类号： A61B18/1445 ,  A61B18/1492 ,  A61N1/056 ,  A61B10/06 ,  A61B18/1402 ,  A61B18/148 ,  A61B2017/003 ,  A61B2018/00279 ,  A61B2018/00577 ,  A61B2018/00839 ,  A61B2018/00916 ,  A61B2018/126 ,  A61B2018/162

    摘要： A deflectable catheter for ablating tissue in the heart of a patient comprising: an axially elongated catheter shaft sized and constructed to be advanced through the vasculature of a patient into the patient's heart; a deflection wire; and an ablation electrode having first and second opposed electrically conductive surfaces exposable for contact with a selected area of tissue within the patient's heart and movable with respect to each other to apply gripping force to the contacted area of heart tissue for stabilizing the position of the electrically conductive surfaces of the ablation electrode relative to the selected area of heart tissue. The ablation electrode has a first rigid surface exposed for contact with the vasculature of the patient during advancement of the catheter therethrough and has an electrically conductive second rigid surface exposable for contact with a selected area of tissue within the patient's heart, wherein the axially transverse area circumscribed by the first surface of the ablation electrode is less than the tissue-contacting area exposable by the second rigid surface. Therapeutic treatments of the heart of a patient are also disclosed.

    摘要翻译： 1.一种用于在患者心脏中烧蚀组织的可偏转导管，包括：轴向细长的导管轴，其大小和构造为通过患者的脉管系统进入患者的心脏; 偏转线; 以及消融电极，其具有可暴露于与患者心脏内的组织的选定区域相对于彼此移动的第一和第二相对的导电表面，以可相对于彼此移动以向心脏组织的接触区域施加夹紧力，以稳定电气位置 消融电极的导电表面相对于心脏组织的选定区域。 消融电极具有暴露于与导管穿过其中的患者的脉管系统接触的第一刚性表面，并且具有可暴露于与患者心脏内的组织的选定区域接触的导电的第二刚性表面，其中轴向横向区域 由消融电极的第一表面限定的面积小于由第二刚性表面可暴露的组织接触面积。 还公开了患者心脏的治疗方法。