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公开(公告)号：US11885818B2
公开(公告)日：2024-01-30
申请号：US17155054
申请日：2021-01-21
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Dieter Heindl , Hans-Peter Josel , Uwe Kobold , Christoph Seidel , Martin Rempt , Andreas Leinenbach , Giuseppe Prencipe , Silvia Baecher , Simon Ferdinand Loibl , Anna-Skrollan Geiermann , Jelena Milic , Nicole Pirkl
IPC: C07D401/06 , C07D413/06 , G01N33/74 , G01N33/58 , C07J43/00
CPC classification number: G01N33/743 , C07D401/06 , C07D413/06 , C07J43/003 , G01N33/58 , G01N2560/00
Abstract: The present invention relates to reagents which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said reagents.
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公开(公告)号：US20230333113A1
公开(公告)日：2023-10-19
申请号：US18306195
申请日：2023-04-24
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Dieter Heindl , Uwe Kobold , Martin Rempt , Christoph Zuth
CPC classification number: G01N33/58 , G01N33/743 , G01N2560/00
Abstract: The present invention relates to a method, a diagnostic system, a kit and the use thereof for efficiently detection of an analyte of interest by nanoESI mass spectrometry.
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公开(公告)号：US20230266283A1
公开(公告)日：2023-08-24
申请号：US18107996
申请日：2023-02-09
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Dieter Heindl , Martin Rempt , Manuel Josef Seitz , Christoph Zuth
IPC: G01N30/72 , G01N33/543 , G01N33/53
CPC classification number: G01N30/72 , G01N33/54386 , G01N33/5304 , G01N2560/00
Abstract: The present invention relates to a method for determining at least one analyte of interest. The present invention further relates to a sample element, a device, a kit and the use thereof for determining at least one analyte of interest.
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公开(公告)号：US11442046B2
公开(公告)日：2022-09-13
申请号：US16520696
申请日：2019-07-24
Inventor： Thomas Carell , Uwe Kobold , Dieter Heindl , Silvia Baecher , Andreas Leinenbach , Martin Rempt , Toni Pfaffeneder , Angie Kirchner , Olesea Kosmatchev , Rene Rahimoff , Sarah Schiffers , Markus Muller
IPC: G01N30/72 , C07D249/04 , H01J49/00 , H01J49/06 , H01J49/10
Abstract: The present invention relates to reagents suitable in the mass spectrometric determination of analyte molecules such as carbohydrates as well as adducts of such reagents and analyte molecules and applications of said reagents and adducts. Further, the present invention relates to methods for the mass spectrometric determination of analyte molecules.
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公开(公告)号：US20240145227A1
公开(公告)日：2024-05-02
申请号：US18410961
申请日：2024-01-11
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Martin Rempt , Manuel Josef Seitz , Christoph Zuth
IPC: H01J49/16 , G01N27/623
CPC classification number: H01J49/164 , G01N27/623
Abstract: A target (110) for use in a laser desorption mass spectrometer is disclosed. The target (110) has at least one surface (112). wherein the surface (112) is covered at least partially with at least one layer (114), wherein the layer (114) is a hydrogen comprising, silicon-incorporated amorphous carbon (a-C:H:Si) layer (116), wherein the a-C:H:Si layer (116) comprises:
40 at. % to 80 at. % of carbon;
1 at. % to 20 at. % of hydrogen; and
10 at. % to 40 at. % of silicon.-
Patent Agency Ranking
公开(公告)号：US20230420240A1
公开(公告)日：2023-12-28
申请号：US18339760
申请日：2023-06-22
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Claudia Epping , Martin Rempt
CPC classification number: H01J49/26 , G01N1/40 , G01N2001/4038
Abstract: The present invention relates to a clinical diagnostic system, a method for determining the presence or level of at least one analyte of interest in a biological sample, a kit and the uses thereof for efficiently and/or robust detection of an analyte of interest.
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公开(公告)号：US11845733B2
公开(公告)日：2023-12-19
申请号：US17155020
申请日：2021-01-21
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Dieter Heindl , Hans-Peter Josel , Uwe Kobold , Christoph Seidel , Martin Rempt , Andreas Leinenbach , Giuseppe Prencipe , Silvia Baecher , Simon Ferdinand Loibl , Anna-Skrollan Geiermann , Jelena Milic , Nicole Pirkl
IPC: C07D249/04 , C07D257/04 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/06 , C07D471/04 , C07D249/06 , C07D203/04 , G01N30/72
CPC classification number: C07D249/06 , C07D203/04 , C07D249/04 , C07D257/04 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/06 , C07D471/04 , G01N30/72
Abstract: The present invention relates to reagents which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said reagents.
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公开(公告)号：US20230324398A1
公开(公告)日：2023-10-12
申请号：US17990903
申请日：2022-11-21
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Dieter Heindl , Uwe Kobold , Hannes Kuchelmeister , Heribert Maerz , Giuseppe Prencipe , Martin Rempt
IPC: G01N33/58
CPC classification number: G01N33/58 , G01N2560/00
Abstract: The present invention relates to compounds which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said compounds.
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公开(公告)号：US20210140983A1
公开(公告)日：2021-05-13
申请号：US17155054
申请日：2021-01-21
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Dieter Heindl , Hans-Peter Josel , Uwe Kobold , Christoph Seidel , Martin Rempt , Andreas Leinenbach , Giuseppe Prencipe , Silvia Baecher , Simon Ferdinand Loibl , Anna-Skrollan Geiermann , Jelena Milic , Nicole Pirkl
IPC: G01N33/74 , C07D401/06 , G01N33/58
Abstract: The present invention relates to reagents which are suitable to be used in mass spectrometry as well as methods of mass spectrometric determination of analyte molecules using said reagents.
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公开(公告)号：US20240310355A1
公开(公告)日：2024-09-19
申请号：US18672786
申请日：2024-05-23
Applicant: Roche Diagnostics Operations, Inc.
Inventor： Martin Rempt , Christian Wellner
IPC: G01N33/487
CPC classification number: G01N33/48721
Abstract: The present invention relates to a method for determining an analyte of interest by frequency detection and the use thereof, a modified nanopore, an analyzing system, a kit and the uses thereof.
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