公开(公告)号：US12105063B2

公开(公告)日：2024-10-01

申请号：US17295985

申请日：2018-12-12

Applicant: SHIMADZU CORPORATION

Inventor： Shotaro Ando ,  Takashi Inoue ,  Kenichi Yasunaga

IPC: G01N30/24 ,  G01N30/18 ,  G01N30/20

CPC classification number: G01N30/24 ,  G01N30/18 ,  G01N30/20 ,  G01N2030/185 ,  G01N2030/207

Abstract: The auto-sampler for chromatographs includes a needle for sampling configured to move while a tip end thereof faces vertically downward; a switching valve having a plurality of ports to which channels constituting a chromatograph are connected, the switching valve switching between port connecting conditions to switch between channel configurations; and an injection port including an opening at an upper surface thereof through which a tip end of the needle is inserted to make the needle fluidically communicate with a pipe connected to one port of the switching valve, and a needle seal configured to get into contact with an outer circumferential surface of the tip end portion to make the needle fluidically communicate with the pipe in a liquid-tight manner when the tip end of the needle is inserted through the opening.

公开(公告)号：US12031959B2

公开(公告)日：2024-07-09

申请号：US17295979

申请日：2018-12-10

Applicant: SHIMADZU CORPORATION

Inventor： Shotaro Ando ,  Takashi Inoue ,  Kenichi Yasunaga

IPC: G01N30/24 ,  G01N30/32

CPC classification number: G01N30/24 ,  G01N30/32 ,  G01N2030/328

Abstract: The auto-sampler for chromatographs includes a sampling needle, a pipe, a pump portion, and a connecting mechanism configured to connect the sampling needle and the pipe. The connecting mechanism includes a first component fixed to the sampling needle, a second component fixed to the pipe, a fixing component, and a packing. The fixing component fixes the first component and the second component using screwing of screws while the end surface of the sampling needle and the end surface of the pipe are in contact with the packing. As a result, dead volume at the connecting portion between the sampling needle and the pipe is reduced.

公开(公告)号：US12247961B2

公开(公告)日：2025-03-11

申请号：US17799741

申请日：2020-02-27

Applicant: SHIMADZU CORPORATION

Inventor： Shotaro Ando ,  Takashi Inoue ,  Tsutomu Watanabe ,  Hiroyuki Minato ,  Nobumitsu Fukushima

IPC: G01N30/60 ,  B01D15/22 ,  G01N30/16 ,  G01N30/32 ,  G01N30/02

Abstract: A column accommodation device (1) includes a housing in which a column accommodation space (4) is provided, and a chip column (6) having a plate-shape and having an internal flow path (40) filled with a separation medium (41) is accommodated in the column accommodation space (4). An outer surface of the chip column (6) is provided with openings (42) respectively communicating with both ends of the internal flow path. Inside of the column accommodation space (4) is provided with a guide (18) for guiding the chip column (6) to a predetermined position. The column accommodation device (1) includes a seal device (32) for connecting and releasing pipes (44) to and from the openings (42) of the chip column (6), and a controller (46) configured to perform operation control of the seal device (32), and the controller (46) is configured to fluidly connect the pipes (44) with respect to the openings (42) of the chip column (6) when it is determined that the chip column (6) is arranged at the predetermined position.

公开(公告)号：US11821878B2

公开(公告)日：2023-11-21

申请号：US17285532

申请日：2018-10-23

Applicant: SHIMADZU CORPORATION

Inventor： Shotaro Ando ,  Takashi Inoue

IPC: G01N30/24 ,  G01N35/10 ,  G01N30/02

CPC classification number: G01N30/24 ,  G01N35/1004 ,  G01N35/1079 ,  G01N2030/027

Abstract: An autosampler includes an injection port for supplying a sample to an analysis device, a needle that collects the sample stored in a vial and injects the sample into the injection port, a cleaning unit that cleans the needle and a gas exhaust fan. The cleaning unit includes a cleaning container which stores a cleaning liquid and into which the needle is inserted, and a unit main body that has a space for storing the cleaning container and receiving the cleaning liquid overflowing from the cleaning container, and a unit gas exhaust passage for exhausting gas in the space outwardly of the cleaning unit. The unit main body has a unit opening through which the needle passes when accessing the cleaning container. The autosampler includes a boundary portion that separates a first region in which the injection port, the needle and the unit opening are arranged from a second region in which the gas exhaust fan is arranged, and a gas exhaust region which is connected to the unit gas exhaust passage via a gas exhaust opening provided at the boundary portion and into which gas exhausted from the space flows due to a negative pressure generated by the gas exhaust fan.