公开(公告)号：US08617381B2

公开(公告)日：2013-12-31

申请号：US12821976

申请日：2010-06-23

申请人： Steve Hoi-Cheong Sun ,  Swetha Chinnayelka ,  John P. Creaven ,  Andrew J. Edelbrock ,  Matthew B. Holzer ,  Narasinha C. Parasnis ,  Jeffery S. Reynolds ,  Paul M. Ripley ,  Steven C. Charlton ,  Xin Wang ,  Mu Wu

发明人： Steve Hoi-Cheong Sun ,  Swetha Chinnayelka ,  John P. Creaven ,  Andrew J. Edelbrock ,  Matthew B. Holzer ,  Narasinha C. Parasnis ,  Jeffery S. Reynolds ,  Paul M. Ripley ,  Steven C. Charlton ,  Xin Wang ,  Mu Wu

IPC分类号： G01N27/416 ,  G01N27/327 ,  G01N21/75

CPC分类号： G01N27/4166 ,  A61B5/01 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1486 ,  G01K3/08 ,  G01K7/01 ,  G01K7/02 ,  G01K7/16 ,  G01K13/00 ,  G01N27/26 ,  G01N27/308 ,  G01N27/3272 ,  G01N27/3274 ,  Y10T29/49155

摘要： A test sensor includes a body, a first conductive trace, a second conductive trace, and a third conductive trace. The body includes a first region that has a fluid-receiving area, a second region separate from the first region, and a first temperature sensing interface disposed at or adjacent to the fluid-receiving area. The fluid-receiving area receives a sample. The first trace is disposed on the body, and at least a portion of the first trace is disposed in the first region. The second and third traces are disposed on the body. The third trace extends from the first to the second regions. The third trace is connected to the first trace at the first temperature sensing interface. The third trace includes a different material than the first trace. A first thermocouple is formed at the first temperature sensing interface. The thermocouple provides temperature data to determine an analyte concentration.

公开(公告)号：US20100319436A1

公开(公告)日：2010-12-23

申请号：US12821976

申请日：2010-06-23

申请人： Steve Hoi-Cheong Sun ,  Swetha Chinnayelka ,  John P. Creaven ,  Andrew J. Edelbrock ,  Matthew B. Holzer ,  Narasinha C. Parasnis ,  Jeffery S. Reynolds ,  Paul M. Ripley ,  Steven C. Charlton ,  Xin Wang ,  Mu Wu

发明人： Steve Hoi-Cheong Sun ,  Swetha Chinnayelka ,  John P. Creaven ,  Andrew J. Edelbrock ,  Matthew B. Holzer ,  Narasinha C. Parasnis ,  Jeffery S. Reynolds ,  Paul M. Ripley ,  Steven C. Charlton ,  Xin Wang ,  Mu Wu

IPC分类号： G01N25/00 ,  G01K7/02 ,  G01K7/16 ,  H05K3/10

CPC分类号： G01N27/4166 ,  A61B5/01 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1486 ,  G01K3/08 ,  G01K7/01 ,  G01K7/02 ,  G01K7/16 ,  G01K13/00 ,  G01N27/26 ,  G01N27/308 ,  G01N27/3272 ,  G01N27/3274 ,  Y10T29/49155

摘要： A test sensor includes a body, a first conductive trace, a second conductive trace, and a third conductive trace. The body includes a first region that has a fluid-receiving area, a second region separate from the first region, and a first temperature sensing interface disposed at or adjacent to the fluid-receiving area. The fluid-receiving area receives a sample. The first trace is disposed on the body, and at least a portion of the first trace is disposed in the first region. The second and third traces are disposed on the body. The third trace extends from the first to the second regions. The third trace is connected to the first trace at the first temperature sensing interface. The third trace includes a different material than the first trace. A first thermocouple is formed at the first temperature sensing interface. The thermocouple provides temperature data to determine an analyte concentration.

摘要翻译： 测试传感器包括主体，第一导电迹线，第二导电迹线和第三导电迹线。 主体包括具有流体接收区域的第一区域，与第一区域分离的第二区域以及设置在流体接收区域处或邻近流体接收区域的第一温度感测界面。 流体接收区域接收样品。 第一迹线设置在主体上，并且第一迹线的至少一部分设置在第一区域中。 第二和第三迹线设置在身体上。 第三个痕迹从第一个区域延伸到第二个区域。 第三个迹线连接到第一个温度检测界面的第一条迹线。 第三个跟踪包含与第一个跟踪不同的材料。 在第一温度感测界面处形成第一热电偶。 热电偶提供温度数据以确定分析物浓度。

公开(公告)号：US09188556B2

公开(公告)日：2015-11-17

申请号：US13884694

申请日：2011-11-07

申请人： Hoi-Cheong Steve Sun ,  John P. Creaven ,  Mu Wu ,  Paul M. Ripley ,  Steven C. Charlton

发明人： Hoi-Cheong Steve Sun ,  John P. Creaven ,  Mu Wu ,  Paul M. Ripley ,  Steven C. Charlton

IPC分类号： G01N27/327 ,  G01N25/00 ,  A61B5/145 ,  A61B5/1486

CPC分类号： G01N27/3274 ,  A61B5/14532 ,  A61B5/1486 ,  A61B2560/0252 ,  A61B2560/0285 ,  A61B2562/12 ,  C12Q1/001 ,  G01K7/02 ,  G01K13/00 ,  G01N25/00 ,  G01N27/3272 ,  Y10T29/49117

摘要： An analyte sensor is provided for detecting an analyte concentration level in a bio-fluid sample. The analyte sensor has a base, a first electrode and a second electrode wherein a thermocouple portion is provided integral with the second electrode thereby enabling on-sensor temperature measurement capability. In some embodiments, two and only two electrical contact engagement portions are provided thereby simplifying electrical contact. Manufacturing methods and systems utilizing the analyte sensors are provided, as are numerous other aspects.

摘要翻译： 提供分析物传感器用于检测生物流体样品中的分析物浓度水平。 分析物传感器具有基座，第一电极和第二电极，其中热电偶部分与第二电极一体设置，从而实现传感器温度测量能力。 在一些实施例中，提供两个且仅两个电接触接合部分，从而简化电接触。 提供了利用分析物传感器的制造方法和系统，以及许多其它方面。

公开(公告)号：US20130298648A1

公开(公告)日：2013-11-14

申请号：US13884694

申请日：2011-11-07

申请人： Hoi-Cheong Steve Sun ,  John P. Creaven ,  Mu Wu ,  Paul M. Ripley ,  Steven C. Charlton

发明人： Hoi-Cheong Steve Sun ,  John P. Creaven ,  Mu Wu ,  Paul M. Ripley ,  Steven C. Charlton

IPC分类号： G01N27/327 ,  G01N25/00

CPC分类号： G01N27/3274 ,  A61B5/14532 ,  A61B5/1486 ,  A61B2560/0252 ,  A61B2560/0285 ,  A61B2562/12 ,  C12Q1/001 ,  G01K7/02 ,  G01K13/00 ,  G01N25/00 ,  G01N27/3272 ,  Y10T29/49117

摘要： An analyte sensor is provided for detecting an analyte concentration level in a bio-fluid sample. The analyte sensor has a base, a first electrode and a second electrode wherein a thermocouple portion is provided integral with the second electrode thereby enabling on-sensor temperature measurement capability. In some embodiments, two and only two electrical contact engagement portions are provided thereby simplifying electrical contact. Manufacturing methods and systems utilizing the analyte sensors are provided, as are numerous other aspects.

摘要翻译： 提供分析物传感器用于检测生物流体样品中的分析物浓度水平。 分析物传感器具有基座，第一电极和第二电极，其中热电偶部分与第二电极一体设置，从而实现传感器温度测量能力。 在一些实施例中，提供两个且仅两个电接触接合部分，从而简化电接触。 提供了利用分析物传感器的制造方法和系统，以及许多其它方面。

公开(公告)号：US09378443B2

公开(公告)日：2016-06-28

申请号：US12779443

申请日：2010-05-13

申请人： Paul M. Ripley ,  Xin Wang ,  Narasinha Parasnis ,  Swetha Chinnayelka

发明人： Paul M. Ripley ,  Xin Wang ,  Narasinha Parasnis ,  Swetha Chinnayelka

IPC分类号： G06K7/12 ,  G06K19/06 ,  G06K7/10

CPC分类号： G06K7/10712 ,  G06K19/06009 ,  G06K19/0614 ,  G06K2019/06225

摘要： In some aspects, a colored coded analyte sensor is provided. The analyte sensor has a body and a plurality of machine-readable colored codes associated with the body. The colored codes may contain red, green, and blue hues, which are discernable into coded information. The coded information may include the analyte sensor model, analyte sensor calibration constant, expiration or manufacture date of the analyte sensor, analyte sensor counterfeiting codes, warnings, messages to the user, etc. Colored code reading systems, apparatus and methods for reading such color-coded information associated with the analyte sensor are provided, as are numerous other aspects.

摘要翻译： 在一些方面，提供了彩色编码的分析物传感器。 分析物传感器具有与身体相关联的主体和多个机器可读的有色代码。 彩色代码可能包含红色，绿色和蓝色色调，可以识别为编码信息。 编码信息可以包括分析物传感器模型，分析物传感器校准常数，分析物传感器的到期或制造日期，分析物传感器假冒代码，警告，给用户的消息等。用于读取这种颜色的有色代码读取系统，装置和方法 提供与分析物传感器相关联的编码信息，以及许多其它方面。

公开(公告)号：US20100288841A1

公开(公告)日：2010-11-18

申请号：US12779443

申请日：2010-05-13

申请人： Paul M. Ripley ,  Xin Wang ,  Narasinha Parasnis ,  Swetha Chinnayelka

发明人： Paul M. Ripley ,  Xin Wang ,  Narasinha Parasnis ,  Swetha Chinnayelka

IPC分类号： G06K7/12 ,  G06K19/00

CPC分类号： G06K7/10712 ,  G06K19/06009 ,  G06K19/0614 ,  G06K2019/06225

摘要： In some aspects, a colored coded analyte sensor is provided. The analyte sensor has a body and a plurality of machine-readable colored codes associated with the body. The colored codes may contain red, green, and blue hues, which are discernable into coded information. The coded information may include the analyte sensor model, analyte sensor calibration constant, expiration or manufacture date of the analyte sensor, analyte sensor counterfeiting codes, warnings, messages to the user, etc. Colored code reading systems, apparatus and methods for reading such color-coded information associated with the analyte sensor are provided, as are numerous other aspects.

摘要翻译： 在一些方面，提供了彩色编码的分析物传感器。 分析物传感器具有与身体相关联的主体和多个机器可读的有色代码。 彩色代码可能包含红色，绿色和蓝色色调，可以识别为编码信息。 编码信息可以包括分析物传感器模型，分析物传感器校准常数，分析物传感器的到期或制造日期，分析物传感器假冒代码，警告，给用户的消息等。用于读取这种颜色的有色代码读取系统，装置和方法 提供与分析物传感器相关联的编码信息，以及许多其它方面。

公开(公告)号：US09949672B2

公开(公告)日：2018-04-24

申请号：US12963579

申请日：2010-12-08

申请人： David A. Simmons ,  Jeffery S. Reynolds ,  Paul M. Ripley ,  Stanley A. Telson

发明人： David A. Simmons ,  Jeffery S. Reynolds ,  Paul M. Ripley ,  Stanley A. Telson

IPC分类号： A61B5/145 ,  A63B71/06 ,  A61B5/00

CPC分类号： A61B5/14532 ,  A61B5/14546 ,  A61B5/743 ,  A63B71/0619 ,  A63B2230/20 ,  A63B2230/202

摘要： Embodiments of the invention provide apparatus, systems and methods wherein pre-event and post-event analyte concentration readings associated with an event are collected and processed to determine a numerical delta. The numerical delta may be displayed on a visual display to aid in a ready determination of the affect that the event (alone or in combination with medication and/or insulin dosages) had on the analyte concentration levels. Medication and/or insulin dosages may be displayed alongside the numerical delta to gauge immediate relationships between numerical delta, dosage and/or an associated event. Apparatus and systems for calculating and displaying the numerical delta are described, as are other aspects.

公开(公告)号：US20110148905A1

公开(公告)日：2011-06-23

申请号：US12963579

申请日：2010-12-08

申请人： David A. Simmons ,  Jeffery S. Reynolds ,  Paul M. Ripley ,  Stanley A. Telson

发明人： David A. Simmons ,  Jeffery S. Reynolds ,  Paul M. Ripley ,  Stanley A. Telson

IPC分类号： G06T11/20 ,  G09G5/02 ,  G06F19/00 ,  G01N33/48

CPC分类号： A61B5/14532 ,  A61B5/14546 ,  A61B5/743 ,  A63B71/0619 ,  A63B2230/20 ,  A63B2230/202

摘要： Embodiments of the invention provide apparatus, systems and methods wherein pre-event and post-event analyte concentration readings associated with an event are collected and processed to determine a numerical delta. The numerical delta may be displayed on a visual display to aid in a ready determination of the affect that the event (alone or in combination with medication and/or insulin dosages) had on the analyte concentration levels. Medication and/or insulin dosages may be displayed alongside the numerical delta to gauge immediate relationships between numerical delta, dosage and/or an associated event. Apparatus and systems for calculating and displaying the numerical delta are described, as are other aspects.

摘要翻译： 本发明的实施方案提供了与事件相关联的事件前事件和事件后分析物浓度读数被收集和处理以确定数值增量的装置，系统和方法。 数字增量可以显示在视觉显示器上以帮助准备确定事件（单独或与药物和/或胰岛素剂量组合）对分析物浓度水平的影响。 药物和/或胰岛素剂量可以与数字增量一起显示，以测量数字增量，剂量和/或相关事件之间的即时关系。 与其他方面一样，描述用于计算和显示数值增量的装置和系统。

公开(公告)号：US20120142084A1

公开(公告)日：2012-06-07

申请号：US13389778

申请日：2010-08-11

申请人： Nancy Dunne ,  Kripa Gaonkar ,  Paul M. Ripley ,  Hoi-Cheong Steve Sun ,  Stanley A. Telson ,  Mu Wu

发明人： Nancy Dunne ,  Kripa Gaonkar ,  Paul M. Ripley ,  Hoi-Cheong Steve Sun ,  Stanley A. Telson ,  Mu Wu

IPC分类号： C12M1/34 ,  G01N33/48

CPC分类号： A61B5/7475 ,  A61B5/14532 ,  A61B2562/0295 ,  G16H40/63

摘要： Diagnostic systems include a meter that is configured to receive a test sensor during a testing procedure. The diagnostic systems also include a computing device coupled to the meter. The test sensor receives a fluid sample during the testing procedure. The meter includes a measurement system that determines a measurement of a concentration of an analyte in the fluid sample. The computing device receives and processes the measurement from the meter. The computing device has enhanced processing and presentation capabilities that provide visual and/or audio instructions on how to operate the diagnostic system, especially when an error or exceptional condition arises.

摘要翻译： 诊断系统包括配置为在测试过程中接收测试传感器的仪表。 诊断系统还包括耦合到仪表的计算设备。 测试传感器在测试过程中接收流体样品。 仪表包括测量系统，其确定流体样品中分析物浓度的测量。 计算设备从仪表接收并处理测量。 计算设备具有增强的处理和呈现能力，其提供关于如何操作诊断系统的视觉和/或音频指令，特别是当出现错误或异常情况时。

公开(公告)号：US20120123227A1

公开(公告)日：2012-05-17

申请号：US12944259

申请日：2010-11-11

申请人： Hoi-Cheong Steve Sun ,  Paul M. Ripley ,  Mu Wu

发明人： Hoi-Cheong Steve Sun ,  Paul M. Ripley ,  Mu Wu

IPC分类号： A61B5/151

CPC分类号： A61B5/14532 ,  A61B5/0024 ,  A61B5/14735 ,  A61B5/15087 ,  A61B5/150969 ,  A61B5/157 ,  A61B2560/0204 ,  A61B2560/045 ,  A61B2562/0295

摘要： Embodiments provide apparatus, systems, and methods adapted to communicate analyte data and/or related information. In a first aspect, the apparatus includes a transmitter/receiver unit which is configurable as either a transmitter or a receiver. The transmitter/receiver unit may be coupled to an on-body sensor and may be configured as a transmitter, or may be coupled to a management unit and may be configured as a receiver as part of a continuous analyte monitoring system. Analyte data communication systems and methods are provided, as are other aspects.

摘要翻译： 实施例提供适于传送分析物数据和/或相关信息的装置，系统和方法。 在第一方面，该装置包括可配置为发射机或接收机的发射机/接收机单元。 发射器/接收器单元可以耦合到体内传感器并且可以被配置为发射器，或者可以耦合到管理单元，并且可以被配置为作为连续分析物监测系统的一部分的接收器。 提供分析物数据通信系统和方法，以及其他方面。