公开(公告)号：US10667897B2

公开(公告)日：2020-06-02

申请号：US15879301

申请日：2018-01-24

Applicant: University of Washington

Inventor： Buddy D. Ratner ,  Le Zhen ,  Felix Simonovsky ,  Jonathan Himmelfarb

IPC: A61F2/06 ,  A61L27/56 ,  A61L27/50 ,  A61L27/18 ,  A61L33/00 ,  A61L27/34

Abstract: Synthetic polymeric vascular grafts that promote endothelial healing and methods of their preparation and use are provided.

公开(公告)号：US20240279504A1

公开(公告)日：2024-08-22

申请号：US18465867

申请日：2023-09-12

Applicant: University of Washington

Inventor： Shaoyi Jiang ,  Xiaojie Lin ,  Jonathan Himmelfarb ,  Buddy D. Ratner

IPC: C09D133/26 ,  A61L29/04 ,  A61L29/06 ,  A61L29/08 ,  A61L29/14 ,  C08J3/28

CPC classification number: C09D133/26 ,  A61L29/041 ,  A61L29/06 ,  A61L29/085 ,  A61L29/141 ,  C08J3/28 ,  C08J2333/26

Abstract: Zwitterionic carboxybetaine copolymers and their use in coatings to impart non-fouling and functionality to surfaces, particularly surfaces of blood-contacting medical devices.

公开(公告)号：US20230173459A1

公开(公告)日：2023-06-08

申请号：US18056994

申请日：2022-11-18

Applicant: University of Washington

Inventor： Buddy D. Ratner ,  Runbang Tang

IPC: B01J20/26 ,  A61M1/16 ,  B01D15/38 ,  B01J20/28

CPC classification number: B01J20/268 ,  A61M1/1696 ,  B01D15/3852 ,  B01J20/28004 ,  B01J20/267

Abstract: The present disclosure features a composition, including molecularly imprinted crosslinked polymers that have been imprinted with trimethylamine N-oxide. The molecularly imprinted crosslinked polymers have specific binding sites for trimethylamine N-oxide, and a trimethylamine N-oxide absorption capacity of at least 0.5 mg/g.

公开(公告)号：US20210403613A1

公开(公告)日：2021-12-30

申请号：US17357887

申请日：2021-06-24

Applicant: University of Washington

Inventor： Buddy D. Ratner ,  Lars Crawford

IPC: C08F2/44 ,  C08G61/12 ,  C08F20/06 ,  C08F12/30 ,  C08K5/00 ,  C08L33/10 ,  C08F2/50

Abstract: Methods for making a conductive hydrogel, comprising photochemically polymerizing polymerizable hydrogel-forming agents in the presence of a polymerizable conductive monomer to provide a conductive hydrogel; liquid resins for preparing conductive hydrogels comprising photochemically polymerizable hydrogel-forming agents and polymerizable conductive monomers; conductive hydrogels prepared by the methods or from the liquid resins; and electrodes comprising the conductive hydrogels.

公开(公告)号：US20200316563A1

公开(公告)日：2020-10-08

申请号：US16837828

申请日：2020-04-01

Applicant: University of Washington

Inventor： Buddy D. Ratner ,  Runbang Tang

IPC: B01J20/26 ,  A61M1/16 ,  B01J20/28 ,  B01D15/38

Abstract: The present disclosure features a composition, including molecularly imprinted crosslinked polymers that have been imprinted with trimethylamine N-oxide. The molecularly imprinted crosslinked polymers have specific binding sites for trimethylamine N-oxide, and a trimethylamine N-oxide absorption capacity of at least 0.5 mg/g.

公开(公告)号：US20200261207A1

公开(公告)日：2020-08-20

申请号：US16861104

申请日：2020-04-28

Applicant: University of Washington

Inventor： Buddy D. Ratner ,  Le Zhen ,  Felix Simonovsky ,  Jonathan Himmelfarb

IPC: A61F2/06 ,  A61L27/56 ,  A61L27/50 ,  A61L27/18 ,  A61L33/00 ,  A61L27/34

Abstract: Synthetic polymeric vascular grafts that promote endothelial healing and methods of their preparation and use are provided.

公开(公告)号：US12194196B2

公开(公告)日：2025-01-14

申请号：US16861104

申请日：2020-04-28

Applicant: University of Washington

Inventor： Buddy D. Ratner ,  Le Zhen ,  Felix Simonovsky ,  Jonathan Himmelfarb

IPC: A61F2/06 ,  A61L27/18 ,  A61L27/34 ,  A61L27/50 ,  A61L27/56 ,  A61L33/00

Abstract: Synthetic polymeric vascular grafts that promote endothelial healing and methods of their preparation and use are provided.

公开(公告)号：US11524275B2

公开(公告)日：2022-12-13

申请号：US16837828

申请日：2020-04-01

Applicant: University of Washington

Inventor： Buddy D. Ratner ,  Runbang Tang

IPC: B01J20/26 ,  B01J20/28 ,  B01D15/38 ,  A61M1/16

Abstract: The present disclosure features a composition, including molecularly imprinted crosslinked polymers that have been imprinted with trimethylamine N-oxide. The molecularly imprinted crosslinked polymers have specific binding sites for trimethylamine N-oxide, and a trimethylamine N-oxide absorption capacity of at least 0.5 mg/g.

公开(公告)号：US20180206971A1

公开(公告)日：2018-07-26

申请号：US15879301

申请日：2018-01-24

Applicant: University of Washington

Inventor： Buddy D. Ratner ,  Le Zhen ,  Felix Simonovsky ,  Jonathan Himmelfarb

IPC: A61F2/06 ,  A61L27/56 ,  A61L27/50

CPC classification number: A61F2/06 ,  A61F2250/0023 ,  A61F2250/0039 ,  A61F2250/0067 ,  A61L27/18 ,  A61L27/34 ,  A61L27/507 ,  A61L27/56 ,  A61L33/0011 ,  A61L2300/412 ,  A61L2300/42 ,  C08L75/04

Abstract: Synthetic polymeric vascular grafts that promote endothelial healing and methods of their preparation and use are provided.

公开(公告)号：US09307905B2

公开(公告)日：2016-04-12

申请号：US14028303

申请日：2013-09-16

Applicant: University of Washington through its Center for Commercialization

Inventor： Cagdas Varel ,  Tueng T. Shen ,  Karl F. Bohringer ,  Brian Otis ,  Buddy D. Ratner

IPC: A61B3/16 ,  A61B5/00 ,  A61B5/053

CPC classification number: A61B3/16 ,  A61B5/0004 ,  A61B5/0538 ,  A61B5/6821 ,  A61B5/686 ,  Y10T29/49155

Abstract: The present technology relates generally to intraocular pressure (“IOP”) monitoring systems and associated devices and methods. In some embodiments, an intraocular pressure monitoring system configured in accordance with the technology comprises an implantable intraocular assembly and an external unit configured to transmit power to and receive data from the intraocular assembly. The intraocular assembly can include an IOP sensing device embedded within a flexible, expandable annular member. The IOP sensing device can include an antenna, a pressure sensor, and a microelectronic device encapsulated by an elastomer.

Abstract translation: 本技术一般涉及眼内压（“IOP”）监测系统及相关设备和方法。 在一些实施例中，根据该技术配置的眼内压监测系统包括可植入眼内组件和被配置为向眼内组件传输电能并从其接收数据的外部单元。 眼内组件可以包括嵌入柔性可扩张环形构件内的IOP感测装置。 IOP感测装置可以包括天线，压力传感器和由弹性体封装的微电子装置。