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143 条记录 (耗时 0.022 秒)

    Method and composition for reducing contact lens swelling
    1.
    发明授权
    Method and composition for reducing contact lens swelling 失效
    减少隐形眼镜肿胀的方法和组成

    公开(公告)号：US07037469B2

    公开(公告)日：2006-05-02

    申请号：US10392743

    申请日：2003-03-19

    申请人： Zhenze Hu ,  Joseph C. Salamone ,  Dharmendra Jani

    发明人： Zhenze Hu ,  Joseph C. Salamone ,  Dharmendra Jani

    IPC分类号： A61L2/18 ,  C11D1/72 ,  C11D3/37

    CPC分类号： C11D3/3707 ,  A61L12/142 ,  C11D3/0078 ,  C11D3/3773 ,  C11D3/3776

    摘要： The present invention is directed to an ophthalmic solution for soft contact lenses for controlled release of polyethers into an eye's tear film. Polyether components of the subject solution are released from the soft contact lens material matrix over long time periods to produce longer lasting wetting performance, improved lubricity, improved end-of-the-day comfort and reduced feeling of dryness from wearing contact lenses. The present invention also includes the use of cationic polyelectrolytes for controlling the swelling of hydrogel contact lenses typically caused by the absorption of high concentrations of polyethers.

    摘要翻译： 本发明涉及用于将聚醚控制释放到眼睛的泪液膜中的软性隐形眼镜的眼用溶液。 本发明溶液的聚醚组分长时间从软性隐形眼镜材料基质中释放出来，以产生更持久的润湿性能，改善的润滑性，改善了最终的舒适感和减少佩戴隐形眼镜的干燥感。 本发明还包括使用阳离子聚电解质来控制通常由吸收高浓度聚醚引起的水凝胶隐形眼镜的溶胀。

    Method and composition for reducing contact lens swelling
    2.
    发明授权
    Method and composition for reducing contact lens swelling 失效
    减少隐形眼镜肿胀的方法和组成

    公开(公告)号：US07247270B2

    公开(公告)日：2007-07-24

    申请号：US11355143

    申请日：2006-02-15

    申请人： Zhenze Hu ,  Joseph C. Salamone ,  Dharmendra Jani

    发明人： Zhenze Hu ,  Joseph C. Salamone ,  Dharmendra Jani

    IPC分类号： A61L2/18 ,  C11D1/72 ,  C11D3/37 ,  C11D3/48

    CPC分类号： C11D3/3707 ,  A61L12/142 ,  C11D3/0078 ,  C11D3/3773 ,  C11D3/3776

    摘要： The present invention is directed to an ophthalmic solution for soft contact lenses for controlled release of polyethers into an eye's tear film. Polyether components of the subject solution are released from the soft contact lens material matrix over long time periods to produce longer lasting wetting performance, improved lubricity, improved end-of-the-day comfort and reduced feeling of dryness from wearing contact lenses. The present invention also includes the use of cationic polyelectrolytes for controlling the swelling of hydrogel contact lenses typically caused by the absorption of high concentrations of polyethers.

    摘要翻译： 本发明涉及用于将聚醚控制释放到眼睛的泪液膜中的软性隐形眼镜的眼用溶液。 本发明溶液的聚醚组分长时间从软性隐形眼镜材料基质中释放出来，以产生更持久的润湿性能，改善的润滑性，改善了最终的舒适感和减少佩戴隐形眼镜的干燥感。 本发明还包括使用阳离子聚电解质来控制通常由吸收高浓度聚醚引起的水凝胶隐形眼镜的溶胀。

    Siloxane prepolymer containing pendant cationic and polymerizable groups
    8.
    发明授权
    Siloxane prepolymer containing pendant cationic and polymerizable groups 有权
    含有阳离子和可聚合基团的硅氧烷预聚物

    公开(公告)号：US08828420B2

    公开(公告)日：2014-09-09

    申请号：US11611508

    申请日：2006-12-15

    申请人： Derek A. Schorzman ,  Joseph C. Salamone ,  Jay F. Kunzler

    发明人： Derek A. Schorzman ,  Joseph C. Salamone ,  Jay F. Kunzler

    IPC分类号： A61K9/00 ,  G02B1/04 ,  C08G77/388

    CPC分类号： C08G77/388 ,  G02B1/043

    摘要： The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic random copolymers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymer compositions comprise polymerized siloxane prepolymer containing pendant cationic and polymerizable groups.

    摘要翻译： 本发明涉及可用于制造生物相容性医疗器械的聚合物组合物。 更具体地，本发明涉及能聚合形成具有用于制造眼科装置的理想物理特性的聚合物组合物的某些阳离子无规共聚物。 这些性质包括用水提取聚合的医疗装置的能力。 这避免了使用本领域典型的有机溶剂。 聚合物组合物包含聚合的含有阳离子和可聚合基团的聚硅氧烷预聚物。

    Conformable solvent-based bandage and coating material
    9.
    发明授权
    Conformable solvent-based bandage and coating material 有权
    符合溶剂型绷带和涂层材料

    公开(公告)号：US08491881B2

    公开(公告)日：2013-07-23

    申请号：US13460553

    申请日：2012-04-30

    申请人： Ann Beal Salamone ,  Joseph C. Salamone

    发明人： Ann Beal Salamone ,  Joseph C. Salamone

    IPC分类号： A61K31/74

    CPC分类号： A61L26/0019 ,  A61K31/785 ,  A61L24/0021 ,  A61L24/043 ,  A61L24/06 ,  C08L35/04

    摘要： A biological coating material that includes a polymerizable polyacrylate monomer; a volatile liquid; a polymer selected from a synthetic rubber, a natural rubber, and a thermoplastic elastomer. The biological liquid coating material forms a coating or bandage in the form of a film that when applied and adhered to a surface or to the skin of a user inhibits the application surface from adhering to another surface.

    摘要翻译： 一种生物涂料，包括可聚合的丙烯酸酯单体; 挥发性液体; 选自合成橡胶，天然橡胶和热塑性弹性体的聚合物。 生物液体涂覆材料形成薄膜形式的涂层或绷带，当施加并粘附到使用者的表面或皮肤时，该涂层或绷带可以阻止施用表面粘附到另一个表面。

    High water content ophthalmic devices
    10.
    发明授权
    High water content ophthalmic devices 有权
    高含水量的眼科装置

    公开(公告)号：US08389597B2

    公开(公告)日：2013-03-05

    申请号：US13370364

    申请日：2012-02-10

    申请人： Richard I. Blackwell ,  Joseph C. Salamone ,  Jay F. Kunzler

    发明人： Richard I. Blackwell ,  Joseph C. Salamone ,  Jay F. Kunzler

    IPC分类号： G02B1/04

    CPC分类号： G02B1/043

    摘要： An ophthalmic device is disclosed that is a polymerization product of a monomeric mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; (b) a hydrophobic monomer; and (c) a crosslinking agent, wherein the ophthalmic device has an equilibrium water content of at least about 70 weight percent and further wherein the ophthalmic device has an evaporative dehydration barrier layer on the surface thereof. A method for the mitigation of evaporative corneal dehydration employing the high water content ophthalmic device is also disclosed.

    摘要翻译： 公开了一种眼科装置，其是单体混合物的聚合产物，其包含（a）主要量的非含硅氧烷的亲水性单体; （b）疏水单体; 和（c）交联剂，其中所述眼科装置具有至少约70重量％的平衡水含量，并且其中所述眼科装置在其表面上具有蒸发性脱水阻隔层。 还公开了一种使用高含水量眼科装置缓解蒸发角膜脱水的方法。