Abstract:
A one pot process for the synthesis of Irbesartan comprising reacting 2-n-Butyl-1,3-Diazaspiro[4,4]Non-1-en-4-one (Formula III) and Bromomethyl Cyanobiphenyl (Formula IV) in the presence of base and water with the optional use of PTC to give formula II from which Irbesartan is obtained by reacting with sodium azide and triethylamine hydrochloride in the presence of a non polar solvent.
Abstract:
Aspects of the subject matter described herein relate to backup up data. In aspects, a backup target determines a degree to which a data set included on the backup target is not backed up on a backup facility. The degree can represent more than just that the data set is completely backed up or is not backed up at all. If the degree satisfies a condition, the backup target utilizes information derived from a backup history of one or more attempted or successfully completed backup sessions between the backup target and the backup facility to determine whether to provide a notification regarding backup state. The backup target also may send the degree and other backup information to a backup facility which may use this information in determining a backup scheme to employ with the backup target.
Abstract:
One embodiment of the present invention provides a system for facilitating cost-optimized mobile messaging. During operation, the system receives an encoded text message at a mobile device. Next, the system replaces a sub-string in the encoded text message with a corresponding sub-string from a data-dictionary to create a decoded text message. Finally, the system displays the decoded text message on the mobile device. Note that this helps to reduce costs since small sub-strings in the encoded text message can be replaced with large sub-strings in the decoded text message, thereby allowing a larger message to be sent via the SMS protocol without sending as many characters.
Abstract:
The present disclosure relates to an approach by which low-performing turbines may be identified from among a plurality of wind turbines, such as may be present at a wind power plant. In accordance with one embodiment, low-performing turbines are identified from among pairs of turbines and based upon a comparison of the observed and expected performance of the turbines within each pair.
Abstract:
The present invention provides novel substituted flavone derivatives which exhibit anti-hyperglycemic and antidyslipedemic activity. The invention also provides a method for controlling type II diabetes and associated hyperlipidemic conditions in a mammal by administering compound of the present invention and compositions containing these derivatives.
Abstract:
A process for preparation of 7-[D-α-amino-α-(4-hydroxyphenyl)acetamido]-3-(1-propen-1-yl)-3-cephem-4-carboxylic acid viz. Cefprozil of formula (I) in high purity, substantially free of impurities, which comprises preparation of mixed acid anhydride by selecting the sequence and temperature of addition of the reagents and its subsequent condensation with a protected 7-APCA; followed by hydrolysis, isolation and purification to give Cefprozil of formula (I) in the form of a monohydrate.
Abstract:
The present invention provides a novel herbal composition, which promotes the proven pharmacological activities such as anti-oxidant, anti-stress and adaptogenic activities. Composition(s) comprises of plant juices or extracts together with the conventional recipients to form paste/jelly/jam/cake/cream puff/chocolate forms fortified with plants like Mangifera indica, Evolvulus alsinoides, Withania somnifera and Asparagus racemosus Amaranthus hypochondriacus which are used as functional foods.
Abstract:
Methods and systems for efficient file replication are provided. In some embodiments, one or more coarse signatures for blocks in a base file are compared with those coarse signatures for blocks of a revised file, until a match is found. A fine signature is then generated for the matching block of the revised file and compared to a fine signature of the base file. Thus, fine signatures are not computed unless a coarse signature match has been found, thereby minimizing unneeded time-consuming fine signature calculations. Methods are also provided for determining whether to initiate a delta file generation algorithm, or whether to utilize a more efficient replication method, based upon system and/or file parameters. In accordance with additional embodiments, the lengths of valid data on physical blocks are obtained from physical block mappings for the files, and these lengths and mappings are utilized for delta file generation, to minimize unnecessary signature computations.
Abstract:
The present invention relates to an improved process of analytical and quantitative isolation of withaferin-A from Withania somnifera (Sanskrit: Ashwagandha, English: winter cherry) and other plants and products therefrom, said method comprising steps of selecting most appropriate extraction medium composition, with extraction solvent system consisting of a defined admixture of water and alcohol in a range of proportion of alcohol within a narrow range of (methanol, ethanol etc.) (preferably 60% alcohol and 40% water) for the dry plant material and from 60% to 80% alcohol in the alcohol-water mixture for fresh plant material, the invented extractant composition leading to better/improved yields and accurate quantitative estimations of withaferin A existent in planta or in materia, selecting effective state of the tissue particularly use of the fresh materials improving yields, providing logistic benefits of isolations and diagnosis, and according several other advantages including technological, economic, preventing contaminations etc., the said method being valuable and advantageous for standardization of botanicals, metabolomic characterization of plants particularly chemotypes, analyzing metabolic transitions under physiological, genetical, environmental and biotic perturbations.
Abstract:
A dielectric resonator is disclosed. In one embodiment, the resonator includes i) a conductive case having a plurality of walls which together define an inner space, ii) a substrate placed at the bottom of the conductive case, and iii) a cylindrical dielectric resonator unit, mounted centrally on the substrate having a central longitudinal axis. The cylindrical dielectric resonator unit includes a dumbbell shaped hole located centrally in the resonator unit extending from a top to a bottom of the resonator unit. In one embodiment, the dumbbell shaped hole includes i) a top layer, ii) a bottom layer and iii) an intermediate layer sandwiched between the top and bottom layers. In one embodiment, the substrate and resonator unit are enclosed inside the conductive case.