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181 条记录 (耗时 0.043 秒)

    Foldable spider wheel for ascending and descending stairs
    91.
    发明授权
    Foldable spider wheel for ascending and descending stairs 失效
    折叠式蜘蛛轮上升和下降楼梯

    公开(公告)号：US07669862B2

    公开(公告)日：2010-03-02

    申请号：US11796381

    申请日：2007-04-27

    申请人： Steven Kamara ,  Michael Yang ,  David Follette

    发明人： Steven Kamara ,  Michael Yang ,  David Follette

    IPC分类号： B62B5/02

    CPC分类号： B62B5/026 ,  A45C5/14 ,  A45C5/146 ,  A45C2005/148 ,  B62B2205/12

    摘要： A collapsible spider wheel assembly on a towing device enables storage of the device into a standard rectangular space. Once collapsed, the collapsible spider assembly is protected within the body of the towing device. Furthermore, actuation of the folding and unfolding may be accomplished through the usual telescoping of the carrying handle of such a device, such as in a suitcase embodiment. While the spider wheels are in the open position, the carrying apparatus may exert a drive force to climb up stairs and braking force to descend stairs. The unit operates as a normal wheeled carrying apparatus while traversing a horizontal surface.

    摘要翻译： 牵引装置上的可折叠的蜘蛛轮组件能够将装置存储在标准的矩形空间中。 一旦折叠，可折叠的蜘蛛组件在牵引装置的主体内受到保护。 此外，折叠和展开的致动可以通过诸如在手提箱实施例中的这种装置的携带手柄的通常伸缩来实现。 当轮子处于打开位置时，携带装置可以施加驱动力以爬楼梯和制动力下降楼梯。 该单元在横向水平表面时作为普通轮式搬运装置工作。

    SELECTING PACING SITE OR SITES BASED ON CARDIO-PULMONARY INFORMATION
    92.
    发明申请
    SELECTING PACING SITE OR SITES BASED ON CARDIO-PULMONARY INFORMATION 审中-公开
    选择基于心肺功能信息的PACING SITE或SITES

    公开(公告)号：US20100042174A1

    公开(公告)日：2010-02-18

    申请号：US12190545

    申请日：2008-08-12

    申请人： Steve Koh ,  Michael Yang ,  Kyungmoo Ryu

    发明人： Steve Koh ,  Michael Yang ,  Kyungmoo Ryu

    IPC分类号： A61N1/368

    CPC分类号： A61N1/368 ,  A61N1/36585 ,  A61N1/3684 ,  A61N1/3688 ,  A61N1/3708

    摘要： An exemplary method for multi-tier pacing includes delivering single site, left ventricular pacing, sensing patient activity; comparing the sensed patient activity to a patient activity threshold and, if the sensed patient activity exceeds the patient activity threshold, then delivering multi-site, left ventricular pacing for a predetermined period of time and, after the predetermined period of time, delivering single, site left ventricular pacing. In such a method, the period of time may be determined based on cardio-pulmonary demand. Other exemplary technologies are also disclosed.

    摘要翻译： 用于多层起搏的示例性方法包括递送单位点，左心室起搏，感测患者活动; 将感测的患者活动与患者活动阈值进行比较，并且如果所感测的患者活动超过患者活动阈值，则在预定时间段内递送多部位左心室起搏，并且在预定时间段之后，递送单个， 现场左心室起搏。 在这种方法中，可以基于心肺 - 肺部需求来确定时间段。 还公开了其它示例性技术。

    DIRECT MODE MODULE WITH MOTION FLAG PRECODING AND METHODS FOR USE THEREWITH
    94.
    发明申请
    DIRECT MODE MODULE WITH MOTION FLAG PRECODING AND METHODS FOR USE THEREWITH 有权
    具有运动标志预处理的直接模式模块及其使用的方法

    公开(公告)号：US20090154549A1

    公开(公告)日：2009-06-18

    申请号：US11959429

    申请日：2007-12-18

    申请人： Yinxia (Michael) Yang ,  Xinghai Li ,  Xu Gang (Wilf) Zhao

    发明人： Yinxia (Michael) Yang ,  Xinghai Li ,  Xu Gang (Wilf) Zhao

    IPC分类号： H04B1/66

    CPC分类号： H04N19/57 ,  H04N19/112 ,  H04N19/51 ,  H04N19/70

    摘要： A motion compensation module can be used in a video encoder that encodes, into a processed video signal, a video input signal including a sequence of pictures. The motion compensation module includes a motion flag generation module that generates a motion flag for at least one of the plurality of macroblocks of a first picture of the sequence of pictures based on a corresponding macroblock of a plurality of macroblocks of a second picture of the sequence of pictures. A direct mode motion vector module evaluates a direct mode motion vector for the corresponding macroblock of the second picture, based on the motion flag for the at least one of the plurality of macroblocks of the first picture.

    摘要翻译： 运动补偿模块可以用在视频编码器中，该视频编码器将经处理的视频信号编码成包括一系列图像的视频输入信号。 运动补偿模块包括运动标志生成模块，其基于序列的第二图像的多个宏块中的对应宏块生成图像序列的第一图像的多个宏块中的至少一个宏块的运动标志 的图片。 直接模式运动矢量模块基于第一图像的多个宏块中的至少一个的运动标志来评估第二图像的相应宏块的直接模式运动矢量。

    Grafted seed layer for electrochemical plating
    95.
    发明授权
    Grafted seed layer for electrochemical plating 有权
    用于电化学电镀的接枝种子层

    公开(公告)号：US07504335B2

    公开(公告)日：2009-03-17

    申请号：US11404058

    申请日：2006-04-13

    申请人： Michael Yang ,  Aron Rosenfeld ,  Hooman Hafezi ,  Zhi-Wen Sun ,  John Dukovic

    发明人： Michael Yang ,  Aron Rosenfeld ,  Hooman Hafezi ,  Zhi-Wen Sun ,  John Dukovic

    IPC分类号： H01L21/44

    CPC分类号： H01L23/53238 ,  H01L21/76855 ,  H01L21/76873 ,  H01L2924/0002 ,  H01L2924/00

    摘要： Generally, the process includes depositing a barrier layer and seed layer on a feature formed in a dielectric layer, performing a grafting process, initiating a copper layer and then filing the feature by use of a bulk copper fill process. Copper features formed according to aspects described herein have desirable adhesion properties to a barrier and seed layers formed on a semiconductor substrate and demonstrate enhanced electromigration and stress migration results in the fabricated devices formed on the substrate.

    摘要翻译： 通常，该方法包括在形成在电介质层中的特征上沉积阻挡层和种子层，执行接枝过程，引发铜层，然后通过使用大量铜填充工艺来填充该特征。 根据本文描述的方面形成的铜特征对于形成在半导体衬底上的阻挡层和种子层具有期望的粘附性能，并且证明增强的电迁移和应力迁移导致形成在衬底上的制造器件。

    MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY CRYSTALLINE FORMS AND PROCESS
    97.
    发明申请
    MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY CRYSTALLINE FORMS AND PROCESS 有权
    化合物受体活性晶体结构和过程的调节剂

    公开(公告)号：US20080027083A1

    公开(公告)日：2008-01-31

    申请号：US11782704

    申请日：2007-07-25

    申请人： Michael Yang ,  Robert Cherney ,  Martin Eastgate ,  Siva Prasad ,  Zili Xiao

    发明人： Michael Yang ,  Robert Cherney ,  Martin Eastgate ,  Siva Prasad ,  Zili Xiao

    IPC分类号： A61K31/517 ,  A61P17/06 ,  A61P19/02 ,  A61P25/28 ,  A61P3/00 ,  A61P3/04 ,  A61P3/10 ,  A61P31/18 ,  A61P35/00 ,  A61P9/12 ,  C07D239/84

    CPC分类号： C07D403/12 ,  C07D207/273 ,  C07D317/72 ,  Y02P20/55

    摘要： The present invention provides a novel antagonist or partial agonists/antagonists of MCP-1 receptor activity: N-((1R,2S,5R)-5-(isopropyl(methyl)amino)-2-((S)-2-oxo-3-(6-(trifluoromethyl)quinazolin-4-ylamino)pyrrolidin-1-yl)cyclohexyl)acetamide, or a pharmaceutically acceptable salt, solvate or prodrug, thereof, having an unexpected combination of desirable pharmacological characteristics. Crystalline forms of the present invention are also provided. Pharmaceutical compositions containing the same and methods of using the same as agents for the treatment of inflammatory diseases, allergic, autoimmune, metabolic, cancer and/or cardiovascular diseases is also an objective of this invention. The present disclosure also provides a process for preparing compounds of Formula (I), including N-((1R,2S,5R)-5-(isopropyl(methyl)amino)-2-((S)-2-oxo-3-(6-(trifluoromethyl)quinazolin-4-ylamino)pyrrolidin-1-yl)cyclohexyl)acetamide: wherein R1, R8, R9, R10, and are as described herein. Compounds that are useful intermediates of the process are also provided herein.

    摘要翻译： 本发明提供MCP-1受体活性的新型拮抗剂或部分激动剂/拮抗剂：N - （（1R，2S，5R）-5-（异丙基（甲基）氨基）-2 - （（S） -3-（6-（三氟甲基）喹唑啉-4-基氨基）吡咯烷-1-基）环己基）乙酰胺或其药学上可接受的盐，溶剂合物或前药，具有期望的药理学特征的意想不到的组合。 还提供了本发明的结晶形式。 含有该组合物的药物组合物以及使用其作为治疗炎性疾病，过敏性，自身免疫性，代谢性，癌症和/或心血管疾病的药剂的方法也是本发明的目的。 本公开还提供制备式（I）化合物的方法，包括N - （（1R，2S，5R）-5-（异丙基（甲基）氨基）-2 - （（S）-2-氧代-3 - （6-（三氟甲基）喹唑啉-4-基氨基）吡咯烷-1-基）环己基）乙酰胺其中R 1，R 8，R 9， R SUP，R 10，并且如本文所述。 本文还提供了该方法有用中间体的化合物。

    INTRAPERICARDIAL LEAD
    99.
    发明申请
    INTRAPERICARDIAL LEAD 有权
    国内领先

    公开(公告)号：US20070239244A1

    公开(公告)日：2007-10-11

    申请号：US11691335

    申请日：2007-03-26

    申请人： Kevin L. Morgan ,  Steven R. Conger ,  Anna Barlow ,  Stuart Rosenberg ,  Wenbo Hou ,  Michael Yang ,  Sheldon Williams

    发明人： Kevin L. Morgan ,  Steven R. Conger ,  Anna Barlow ,  Stuart Rosenberg ,  Wenbo Hou ,  Michael Yang ,  Sheldon Williams

    IPC分类号： A61N1/05

    CPC分类号： A61N1/059 ,  A61N1/057 ,  A61N1/0587 ,  A61N2001/058

    摘要： The intrapericardial lead includes a lead body having a proximal portion and a flexible, pre-curved distal end portion. The distal end portion carries at least one electrode assembly containing an electrode adapted to engage pericardial tissue. The distal end portion further carries a pre-curved flexible wire member having ends attached to spaced apart points along the distal end portion of the lead body, the flexible wire member having a normally expanded state wherein an intermediate portion of the wire member is spaced apart from the distal end portion, and a generally straightened state wherein the wire member and the distal end portion are disposed in a more parallel, adjacent relationship so as to present a small frontal area to facilitate delivery into the pericardial space. The wire member re-expands to its normal state after delivery into the percaridal space to anchor the distal end portion of the lead body relative to the pericardial tissue.

    摘要翻译： 心包内引线包括具有近端部分和柔性的预弯曲远端部分的引线体。 远端部分携带至少一个电极组件，其包含适于接合心包组织的电极。 远端部分还承载预弯曲的柔性线构件，其具有沿着引线本体的远端部附接到间隔开的点的端部，柔性线构件具有正常膨胀状态，其中线构件的中间部分间隔开 以及大致直线状态，其中所述线构件和所述远端部分布置成更平行的相邻关系，以便呈现小的前部区域以便于输送到心包空间中。 导线部件在输送到大面积空间之后，再膨胀至其正常状态，以相对于心包组织锚固引线主体的远端部分。

    MULTIPLE CHEMISTRY ELECTROCHEMICAL PLATING METHOD
    100.
    发明申请
    MULTIPLE CHEMISTRY ELECTROCHEMICAL PLATING METHOD 审中-公开
    多种化学电化学镀层法

    公开(公告)号：US20060266655A1

    公开(公告)日：2006-11-30

    申请号：US11425645

    申请日：2006-06-21

    申请人： ZHI-WEN SUN ,  BO ZHENG ,  NICOLAY KOVARSKY ,  YOU WANG ,  TOSHIYUKI NAKAGAWA ,  TERUKAZU AITANI ,  KOJI HARA ,  DAXIN MAO ,  MICHAEL YANG

    发明人： ZHI-WEN SUN ,  BO ZHENG ,  NICOLAY KOVARSKY ,  YOU WANG ,  TOSHIYUKI NAKAGAWA ,  TERUKAZU AITANI ,  KOJI HARA ,  DAXIN MAO ,  MICHAEL YANG

    IPC分类号： C25D5/18

    CPC分类号： C25D5/10 ,  C25D3/38 ,  C25D7/123

    摘要： Embodiments of the invention generally include a method and intermediate plating solution for plating metal onto a substrate surface. The method generally includes filling the features and/or growing a film layer on the field areas by plating a metal from a first solution on a seed layer under an applied first current, wherein the first solution includes an acid in an amount sufficient to provide a first solution pH of about 6 or less, copper ions, and at least one suppressor. The method may further include substantially filling features by plating metal ions from a second solution onto the substrate under an applied second current to form a metal layer, wherein the second solution includes an acid in an amount sufficient to provide a second solution pH of from about 0.6 to about 3, copper ions, at least one suppressor and at least one accelerator and growing a film layer on the field areas by contacting the metal layer with a third solution under an applied third current, wherein the third solution includes an acid, copper ions, at least one suppressor, at least one accelerator and at least one leveling agent. The intermediate plating solution generally includes copper sulfate in a concentration of from about 5 g/L to about 50 g/L, sulfuric acid in a concentration sufficient to provide a pH of less than about 6 and suppressors having a molecular weight of 600 or greater.

    摘要翻译： 本发明的实施例通常包括用于将金属电镀到衬底表面上的方法和中间电镀溶液。 该方法通常包括通过在所施加的第一电流下在种子层上镀覆来自第一溶液的金属，在场区上填充特征和/或生长膜层，其中第一溶液包含足以提供 第一溶液pH为约6以下，铜离子和至少一种抑制剂。 该方法可以进一步包括基本上填充特征，通过在施加的第二电流下将金属离子从第二溶液镀覆到衬底上以形成金属层，其中第二溶液包括足以提供第二溶液的酸，pH约为 0.6至约3，铜离子，至少一种抑制剂和至少一种促进剂，并通过在施加的第三电流下使金属层与第三溶液接触而在场区上生长膜层，其中第三溶液包含酸，铜 至少一种抑制剂，至少一种促进剂和至少一种流平剂。 中间电镀溶液通常包含浓度为约5g / L至约50g / L的硫酸铜，其浓度足以提供小于约6的pH值，分子量为600或更大的抑制剂 。