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公开(公告)号：US06520985B1
公开(公告)日：2003-02-18
申请号：US09688157
申请日：2000-10-16
申请人： Janet Burpee , David R. Fischell
发明人： Janet Burpee , David R. Fischell
IPC分类号： A61F206
CPC分类号： A61F2/91 , A61F2/915 , A61F2/958 , A61F2002/30131 , A61F2002/30135 , A61F2002/30176 , A61F2002/30177 , A61F2002/91541 , A61F2002/91558 , A61F2230/0004 , A61F2230/0013 , A61F2230/0054 , A61F2230/0056 , A61F2310/00017
摘要： A balloon expandable metal stent is provided that includes a multiplicity of circumferential sets of strut members wherein at least two adjacent circumferential sets of strut members are coupled together by a plurality of undulating longitudinal struts. The stent is annealed to a degree where frictional forces existing in the longitudinal direction between adjacent circumferential sets of strut members and the balloon, during inflation, are greater than a force required to permanently deform the undulating longitudinal struts. Thus, the expansion of the space between adjacent circumferential sets of strut members during inflation of the balloon compensates for shortening of the stent that would otherwise occur during radial expansion of the stent responsive to the inflation of the balloon. The undulating longitudinal struts also have a width dimension throughout their length which is less than a width dimension of the circumferential sets of strut members to further facilitate the deformation of the undulating longitudinal struts when the balloon is inflated.
摘要翻译： 提供一种球囊可膨胀金属支架，其包括多个周向组的支柱构件，其中至少两个相邻的周向组支撑构件通过多个起伏的纵向支柱联接在一起。 支架退火到一定程度，其中在充气期间相邻的圆柱形支柱构件和气囊之间存在的纵向方向上的摩擦力大于永久变形起伏纵向支柱所需的力。 因此，球囊充气过程中相邻圆周组的支柱构件之间的空间的膨胀补偿了支架的缩短，否则在支架的径向膨胀期间会响应气囊的膨胀而发生。 起伏的纵向支柱还具有整个长度的宽度尺寸，该宽度尺寸小于圆柱形支柱构件的宽度尺寸，以便当球囊膨胀时进一步促进起伏纵向支柱的变形。
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公开(公告)号：US06315708B1
公开(公告)日：2001-11-13
申请号：US09540629
申请日：2000-03-31
IPC分类号： A61N500
CPC分类号： A61F2/958 , A61F2/90 , A61F2002/9583 , A61F2250/0018 , A61F2250/0042 , A61F2250/0048
摘要： The present invention is a hybrid stent that is defined as having a central section that is balloon expandable and end sections that are self-expanding. The entire stent is mounted on a balloon of a balloon angioplasty catheter. One way to retain the self-expanding portion of the stent onto a balloon onto which it has been nested is to place a cylindrical elastomer tube around each of the self-expanding end sections of the stent. Another way to retain the hybrid stent onto a stent delivery system is to use a conventional sheath that is pulled back to initiate stent deployment
摘要翻译： 本发明是一种混合型支架，其被定义为具有球囊可膨胀的中心部分和自膨胀的端部。 整个支架安装在球囊血管成形术导管的球囊上。 将支架的自膨胀部分保持在其已经嵌套在其上的气球上的一种方法是将圆柱形弹性体管围绕在支架的每个自扩张端部分上。 将混合支架保持在支架输送系统上的另一种方法是使用被拉回以启动支架部署的常规护套
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公开(公告)号：US06270521B1
公开(公告)日：2001-08-07
申请号：US09316843
申请日：1999-05-21
IPC分类号： A61F1100
CPC分类号： A61F2/95 , A61F2/958 , A61F2002/9583 , A61F2250/0036
摘要： An ultra-thin distal sheath section of the sheathed system uses heat shrinkable elastomer tubing with a wall thickness that is less than 0.05 mm and may be less than 0.025 mm. There are two methods for securing the ultra-thin distal sheath section over the distal tip. A first method is to employ another thin tube shrunk down over the distal end of the ultra-thin distal sheath. It is also envisioned that simply shrinking the ultra-thin distal sheath section down on the tapered section of the distal tip will hold it securely. A monorail (rapid exchange) version of this stent delivery system is also envisioned. A second version uses radioopaque elastic bands mounted over the ends of the balloon just proximal and just distal to the stent to provide a low profile for a primary stent delivery system. These radioopaque elastic bands could contain a high-density material such as tungsten to make them radioopaque and eliminate the need for radioopaque markers normally attached to the angioplasty balloon inner shaft.
摘要翻译： 护套系统的超薄远端护套部分使用壁厚小于0.05mm且可能小于0.025mm的热收缩弹性体管。 有两种方法用于将超薄远端鞘部分固定在远端上。 第一种方法是使用在超薄远侧鞘的远端下方收缩的另一条细管。 还可以想到，将超薄远端鞘部分简单地收缩在远侧尖端的锥形部分上将牢固地保持。 还设想了该支架输送系统的单轨（快速交换）版本。 第二个版本使用放射性弹性带，其安装在球囊的端部的刚好在支架的近侧并且仅在支架的远端处，以为主支架输送系统提供低轮廓。 这些不透射线的弹性带可以含有诸如钨的高密度材料，使其不透射线，并且不需要通常附着于血管成形术球囊内轴的不透射线标记。
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公开(公告)号：US6086604A
公开(公告)日：2000-07-11
申请号：US263518
申请日：1999-03-05
CPC分类号： A61F2/844 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91533 , A61F2002/9155 , A61F2210/0019
摘要： The present invention provides for an expandable stent (10 or 20) for use in an artery or other vessel of a human body. The stent structure (10 or 20) maintains the patency of the vessel within which the stent (10 or 20) is expanded radially outward. One embodiment of the present invention is a stent (10) having a multiplicity of frames (12) joined together by at least two undulating longitudinal structures (14L and 14R) which can readily change their length in the longitudinal direction so as to provide increased longitudinal flexibility for the stent (10) for easy passage through and placement within a curved vessel such as a coronary artery. The stent (20) is an embodiment of the present invention having frames (22) joined with longitudinal structures (24B, 24T and 24R) and formed from a single, thin-walled piece of metal by laser cutting or chemical etching. Because the stent (20) is fabricated from a single piece of metal, it provides a multiplicity of closed perimeter cells that are formed as a continuous metal structure.
摘要翻译： 本发明提供一种用于人体动脉或其他血管的可扩张支架（10或20）。 支架结构（10或20）保持支架（10或20）径向向外扩张的容器的通畅性。 本发明的一个实施例是具有通过至少两个起伏的纵向结构（14L和14R）连接在一起的多个框架（12）的支架（10），其可以容易地改变其在纵向上的长度，从而提供增加的纵向 支架（10）的灵活性容易通过并放置在诸如冠状动脉的弯曲容器内。 支架（20）是本发明的实施例，其具有通过激光切割或化学蚀刻由单个薄壁金属片形成的具有纵向结构（24B，24T和24R）的框架（22）。 因为支架（20）由单块金属制成，所以它提供了多个形成为连续金属结构的封闭周边细胞。
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公开(公告)号：US5749825A
公开(公告)日：1998-05-12
申请号：US714315
申请日：1996-09-18
CPC分类号： A61F2/90 , A61F2/954 , A61F2/958 , A61F2/856 , A61F2/91 , A61F2002/065 , A61F2002/067 , A61F2210/0095 , A61F2250/006
摘要： A stent delivery catheter system for the treatment of stenoses at an arterial bifurcation consists of a main guide wire, a side branch guide wire, a unique design balloon angioplasty catheter which includes a side branch tube and a stent that can be deployed to a larger diameter in the main artery leading to the arterial bifurcation, and deployed to a smaller diameter within one of the branch arteries at an arterial bifurcation. The balloon angioplasty catheter used to deploy the dual diameter stent has a proximal section that has a larger diameter as compared to the diameter of a distal section which distal section is designed to be placed in a branch artery of the bifurcation. An opening in the wall of the stent allows for the passage of the side branch tube that provides angular orientation of the pre-deployed stent relative to the two branches of the bifurcation. The side branch tube is also used to help assure proper longitudinal placement of the stent relative to the saddle point of the bifurcation. After the stent is deployed, the opening in the stent wall allows unobstructed blood flow into that side branch artery that is not initially stented.
摘要翻译： 用于治疗动脉分叉狭窄的支架输送导管系统包括主导丝，侧分支引导线，独特的设计球囊血管成形术导管，其包括侧分支管和可以展开到更大直径的支架 在导致动脉分叉的主动脉中，并且在动脉分叉处部署到一个分支动脉内的较小直径。 用于展开双直径支架的球囊血管成形术导管具有与远端部分的直径相比具有较大直径的近端部分，其远端部分被设计成放置在分叉的分支动脉中。 支架壁上的开口允许侧分支管的通过，其提供相对于分叉的两个分支的预先展开的支架的角度定向。 侧支管还用于帮助确保支架相对于分叉的鞍点的适当纵向放置。 在展开支架之后，支架壁中的开口允许无阻塞的血液流入最初不支架的侧支支动脉。
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96.发明授权
公开(公告)号：US5735859A
公开(公告)日：1998-04-07
申请号：US800613
申请日：1997-02-14
摘要： The present invention is a device and method for securing and releasing the distal end of a thin-walled sheath to and from a distal section of a stent delivery catheter. The invention comprises a stent delivery catheter system which includes a sheath which is releasably attached to a distal section of a stent delivery catheter. When the stent delivery system has been advanced into the body so that the stent (which is situated coaxially within the sheath) is placed at the site of an arterial stenosis where it is to be deployed, the sheath is released from the stent delivery catheter and then the sheath is pulled back in a proximal direction thereby uncovering the stent. Self-deploying stents will automatically deploy when the sheath is pulled back. Balloon expandable stents can be deployed by balloon inflation after the sheath has been pulled back. One embodiment of the distally attachable and releasable sheath utilizes a guide wire that passes through the stent delivery catheter first to hold and then to release the distal end of the sheath from a distal section of the stent delivery catheter.
摘要翻译： 本发明是一种用于将薄壁护套的远端固定并释放到支架输送导管的远端部分的装置和方法。 本发明包括支架递送导管系统，其包括可释放地附接到支架递送导管的远端部分的护套。 当支架输送系统已经进入体内，使得支架（其位于鞘内同轴位置）被放置在其将要部署的动脉狭窄部位时，护套从支架输送导管释放，并且 然后将护套沿近侧方向拉回，从而露出支架。 当护套被拉回时，自动部署支架将自动部署。 护套被拉回之后，球囊扩张支架可以通过球囊膨胀进行部署。 远端可附接和可释放的护套的一个实施例使用导线首先穿过支架输送导管以保持，然后从支架输送导管的远端部分释放护套的远端。
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公开(公告)号：US5695516A
公开(公告)日：1997-12-09
申请号：US604682
申请日：1996-02-21
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91541 , A61F2002/91558 , A61F2002/91566 , A61F2250/0067 , A61F2310/00131 , A61F2310/00155
摘要： The present invention is designed to overcome several disadvantages of prior art balloon expandable stents. Specifically, the Butterfly Expandable To Honeycomb (BETH) stent described herein consists of a collection of circumferential (or vertical) arc structures and diagonal struts. These arcs and struts form a butterfly shape before the stent is expanded and a hexagonal, honeycomb type of structure is created when the stent is fully expanded. Until the nominal stent diameter is reached, the deployed length of the stent is actually longer than the non-deployed length. At the nominal fully-deployed diameter, the deployed stent is exactly the same length as the non-deployed length. This characteristic provides better assurance of completely covering a dilated stenosis as compared to a stent that shortens in length when deployed as is typical of all prior art balloon expandable stents. Furthermore, because at least one quarter of the expanded stent's circumference consist of vertical arcs that are arcs of a circle, they provide the BETH stent with improved radial rigidity.
摘要翻译： 本发明被设计为克服现有技术的球囊可扩张支架的若干缺点。 具体来说，本文所述的蝴蝶展开型蜂窝（BETH）支架由周向（或垂直）弧形结构和对角支柱的集合组成。 这些弧形和支柱在支架膨胀之前形成蝴蝶形状，并且当支架完全展开时产生六边形蜂窝型结构。 直到达到标称支架直径，支架的展开长度实际上比非展开长度长。 在标称完全直径的情况下，展开的支架的长度与未展开的长度完全相同。 与所有现有技术的球囊可扩张支架的典型部署时相比，当展开长度缩短的支架时，该特征提供了完全覆盖扩张狭窄的更好的保证。 此外，因为扩张支架的圆周的至少四分之一由垂直圆弧组成，它们是圆弧，它们为BETH支架提供了改进的径向刚度。
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公开(公告)号：US5605530A
公开(公告)日：1997-02-25
申请号：US408780
申请日：1995-03-23
CPC分类号： A61N5/1002 , A61F2/95 , A61F2/0095 , A61N2005/1094 , A61N5/1007
摘要： There is provided a radiation shield for protecting a health care worker from ionizing radiation prior to and during delivery of a radioisotope stent into a patient's blood vessel. The radiation shield is placed coaxially over at least a distal portion of a stent delivery catheter assembly carrying or having formed therein a radioactive stent. The radiation shield is maintained about the distal portion of the catheter assembly until delivery of the radioactive stent is to occur. During the stent's delivery, the catheter assembly is axially displaced relative to the radiation shield to pass therethrough, then into the patient's blood vessel. A protective barrier is thus continually maintained between the health care worker and the radioactive stent he or she is delivering.
摘要翻译： 提供了辐射屏蔽，用于在将放射性同位素支架输送到患者血管之前和期间保护医护人员免受电离辐射。 辐射屏蔽同轴地放置在支架输送导管组件的至少一个远端部分上，该导管组件携带或已经形成放射性支架。 辐射屏蔽围绕导管组件的远端部分保持，直到发生放射性支架的输送。 在支架的输送期间，导管组件相对于辐射屏蔽件轴向移位，从而穿过其中，然后进入患者的血管。 因此，保健工作者和他或她正在投放的放射性支架之间持续保持保护屏障。
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公开(公告)号：US5409454A
公开(公告)日：1995-04-25
申请号：US236249
申请日：1994-05-02
申请人： Robert E. Fischell , James J. Thompson , David R. Fischell , Richard L. Harding , Tim A. Fischell
发明人： Robert E. Fischell , James J. Thompson , David R. Fischell , Richard L. Harding , Tim A. Fischell
CPC分类号： A61B17/320783 , A61B2017/22038 , A61B2017/22051 , A61B2017/320052
摘要： A catheter is disclosed which is capable of cutting obstructive tissue from a vessel of a living body while shielding a portion of the wall of the vessel from being exposed to the cutting blade at the catheter's distal end. An essentially continuous outer surface at the catheter's distal end allows it to be readily advanced through an introducer sheath and through a tight stenosis in an artery. The shield at the catheter's distal end could subtend an arc from as little as 45 degrees to as large as 270 degrees depending on the extent of the vessel wall that is to be protected from being cut. A vacuum source at the catheter's proximal end can cause a suction to exist at a cutout at the catheter's distal end in order to pull obstructive tissue into the cutout as the cutting cylinder is pulled back in a retrograde direction, this suction being capable of enhancing the removal of the obstructive tissue.
摘要翻译： 公开了一种导管，其能够屏蔽来自血管的容器的阻塞性组织，同时屏蔽该容器的壁的一部分在导管远端暴露于切割刀片。 在导管的远端处基本上连续的外表面允许其容易地推进穿过导引鞘并且通过动脉中的狭窄狭窄。 导管远端的护罩可以根据待保护的血管壁的切割程度，从45度到270度的弧度相对应。 在导管的近端处的真空源可以导致在导管远端的切口处存在抽吸，以便当切割圆筒沿逆行方向被拉回时将阻塞性组织拉入切口，该吸力能够增强 去除阻塞性组织。
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公开(公告)号：US5389090A
公开(公告)日：1995-02-14
申请号：US192347
申请日：1994-02-07
IPC分类号： A61M25/06 , A61M25/088 , A61M25/00
CPC分类号： A61M25/0662
摘要： A guiding catheter system (10) is provided that includes a Tuohy-Borst fitting (20) attached as a one-piece construction to a guiding catheter tube (11). The guiding catheter system (10) can also include a dilator (16) and a guide wire 15. The Tuohy-Borst fitting (20) can have a side arm (14) onto which a stop cock (30) can be attached. With the stop cock (30) in its closed position, fluid flow through the side arm (14) is prevented. When the nut (22) on the Tuohy-Borst fitting (20) is tightened down so that the gland (24) in the Tuohy-Borst fitting (20) seals against the guide wire (15) and the stop cock (30) is closed, blood loss through the proximal end of the guiding catheter system (10) can be essentially eliminated. Since the Tuohy-Borst fitting (20) is integrally joined to the proximal end of the guiding catheter tube (11), the need for a separately packaged and sterilized Tuohy-Borst fitting to be screwed onto the guiding catheter's proximal end is eliminated. The dilator (16) with the guide wire (15) can be used to allow percutaneous insertion of the guiding catheter system (10) into a patient's artery without requiring an introducer sheath, thus reducing the size of the hole that is made in the wall of the artery. A smaller hole in the artery's wall reduces the possibility of post-procedure bleeding at that point where the guiding catheter system (10) is inserted.
摘要翻译： 提供了一种引导导管系统（10），其包括以引导导管（11）作为一体结构附接的Tuohy-Borst配件（20）。 引导导管系统（10）还可以包括扩张器（16）和导丝15. Tuohy-Borst配件（20）可以具有侧臂（14），可以在其上安装止动旋塞（30）。 在停止旋塞（30）处于其关闭位置时，流体流过侧臂（14）被阻止。 当Tuohy-Borst配件（20）上的螺母（22）拧紧时，Tuohy-Borst配件（20）中的压盖（24）密封在导丝（15）上，止动螺母（30）是 可以基本上消除通过引导导管系统（10）的近端的失血。 由于Tuohy-Borst配件（20）与引导导管（11）的近端整体连接，所以不需要将单独包装的灭菌的Tuohy-Borst配件拧入导向导管的近端。 具有引导线（15）的扩张器（16）可以用于允许引导导管系统（10）经皮插入病人的动脉中，而不需要引导器护套，从而减小在壁中形成的孔的尺寸 的动脉。 动脉壁上的一个较小的孔减少了引导导管系统（10）插入的那一点的手术后出血的可能性。
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