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    Apparatus and method for auto-titrating a laser
    91.
    发明授权
    Apparatus and method for auto-titrating a laser 有权
    用于自动滴定激光的装置和方法

    公开(公告)号：US08308716B2

    公开(公告)日：2012-11-13

    申请号：US11768576

    申请日：2007-06-26

    申请人： Christopher Horvath

    发明人： Christopher Horvath

    IPC分类号： A61B18/18

    CPC分类号： A61F9/008 ,  A61F9/00821 ,  A61F9/00823 ,  A61F2009/00863 ,  A61F2009/00868

    摘要： An apparatus and method for auto-titrating a surgical laser are disclosed. One embodiment of the method comprises: providing an algorithm, wherein the algorithm is operable to configure the laser based on one or more user inputs; providing a first user input operable to cause the algorithm to execute and fire the laser in a defined pattern; providing a second user input, in response to an observed condition, operable to cause the laser to stop firing and to cause the algorithm to determine one or more laser parameter values and configure the laser based on the one or more laser parameter values, wherein a final laser power value when the laser stops firing is an input to the algorithm and wherein the algorithm determines the one or more laser parameters based on the final laser power value. The method can further comprise placing the laser in a “ready” (surgical) mode, either automatically by the auto-titration algorithm or via another user input. Once in a ready mode, a user, such as a surgeon, can perform a surgical procedure with the automatically configured laser. The user inputs can be provided by activating a control switch, such as the footswitch typically used by ophthalmic surgeons to control the operation of an ophthalmic surgical laser.

    摘要翻译： 公开了一种用于自动滴定手术激光的装置和方法。 该方法的一个实施例包括：提供一种算法，其中该算法可操作以基于一个或多个用户输入来配置激光; 提供第一用户输入，其可操作以使所述算法以限定的模式执行和激发所述激光; 提供响应于观察条件的第二用户输入，其可操作以使激光停止点火，并使算法确定一个或多个激光参数值，并且基于一个或多个激光参数值配置激光，其中a 当激光停止点火时的最终激光功率值是算法的输入，并且其中该算法基于最终的激光功率值确定一个或多个激光参数。 该方法还可以包括通过自动滴定算法或通过另一用户输入自动地将激光置于准备（手术）模式。 一旦处于就绪模式，用户（例如外科医生）可以用自动配置的激光器执行外科手术。 用户输入可以通过激活控制开关来提供，例如通常由眼科医生使用的脚踏开关来控制眼科手术激光器的操作。

    DEVICES FOR DEPLOYING INTRAOCULAR SHUNTS
    94.
    发明申请
    DEVICES FOR DEPLOYING INTRAOCULAR SHUNTS 有权
    用于分配内窥镜的装置

    公开(公告)号：US20120123430A1

    公开(公告)日：2012-05-17

    申请号：US12946251

    申请日：2010-11-15

    申请人： Christopher Horvath ,  Laszlo O. Romoda ,  Guenther Grabner ,  Herbert A. Reitsamer

    发明人： Christopher Horvath ,  Laszlo O. Romoda ,  Guenther Grabner ,  Herbert A. Reitsamer

    IPC分类号： A61F9/007

    CPC分类号： A61F9/00781

    摘要： The present invention generally relates to devices for deploying intraocular shunts without the use of an optical apparatus that contacts an eye, such as a goniolens. In certain embodiments, devices of the invention include a housing including a proximal portion and a distal portion, in which the distal portion is movable within the proximal portion, a deployment mechanism at least partially disposed within the housing, and a hollow shaft coupled to the deployment mechanism, in which the shaft is configured to hold an intraocular shunt.

    摘要翻译： 本发明总体上涉及用于部署眼内分流而不使用与眼睛接触的光学装置（例如巨像）的装置。 在某些实施例中，本发明的装置包括壳体，其包括近端部分和远端部分，远端部分可在近侧部分内移动，至少部分地设置在壳体内的展开机构，以及联接到 展开机构，其中轴被构造成保持眼内分流。

    APPARATUS FOR ENHANCING BRIGHTNESS OF A WAVELENGTH CONVERTING ELEMENT
    95.
    发明申请
    APPARATUS FOR ENHANCING BRIGHTNESS OF A WAVELENGTH CONVERTING ELEMENT 有权
    用于增强波长转换元件亮度的装置

    公开(公告)号：US20110245820A1

    公开(公告)日：2011-10-06

    申请号：US12751127

    申请日：2010-03-31

    申请人： Michael James Papac ,  Christopher Horvath

    发明人： Michael James Papac ,  Christopher Horvath

    IPC分类号： A61B1/07

    CPC分类号： A61B3/0008 ,  A61B1/0653 ,  A61B1/0669 ,  F21K9/64 ,  G02B6/0003 ,  G02B6/0006 ,  G02F1/353 ,  H01L33/505 ,  H01L33/507

    摘要： Disclosed is an exemplary illumination device for enhancing the brightness of wavelength converting element. The illumination device includes a wavelength converting element operable for receiving light from a light source at a first wavelength range and converting the light to a second wavelength range. The wavelength converting element includes a first face, a second face opposite the first face, and a side edge extending between the first and second faces. A reflective optical element is arranged adjacent the side edge of the wave converting element. The reflective optical element is configured to reflect light in at least the first wavelength range toward the wavelength converting element.

    摘要翻译： 公开了一种用于增强波长转换元件的亮度的示例性照明装置。 照明装置包括波长转换元件，其可操作用于从第一波长范围的光源接收光并将光转换成第二波长范围。 波长转换元件包括第一面，与第一面相对的第二面，以及在第一和第二面之间延伸的侧边缘。 反射型光学元件布置成与波转换元件的侧边相邻。 反射光学元件被配置为将至少第一波长范围内的光反射到波长转换元件。

    Footswitch operable to control a surgical system
    96.
    发明授权
    Footswitch operable to control a surgical system 有权
    脚踏开关可操作以控制外科系统

    公开(公告)号：US07781941B2

    公开(公告)日：2010-08-24

    申请号：US11389808

    申请日：2006-03-27

    申请人： Christopher Horvath ,  Mark Buczek ,  T. Scott Rowe

    发明人： Christopher Horvath ,  Mark Buczek ,  T. Scott Rowe

    IPC分类号： H01L41/113 ,  G05G1/30

    CPC分类号： G05G1/38 ,  A61B17/00 ,  A61B34/20 ,  A61B2017/00119 ,  A61B2017/00194 ,  A61B2017/00199 ,  A61B2017/00221 ,  A61B2017/00973 ,  A61C1/0023 ,  H01H21/26 ,  H01H2239/076 ,  H01H2300/014 ,  H01H2300/03 ,  Y02B70/3241 ,  Y04S20/227 ,  Y10T74/2054 ,  Y10T74/20888 ,  Y10T307/747

    摘要： The present invention provides a surgical footswitch that includes a base, a pedal, an encoder assembly, a wireless interface, and an internal power generator. The pedal mounts upon the base and pivots. The encoder assembly couples to the pedal. As the pedal pivots, the encoder assembly translates the mechanical signal of the pedal into a control signal based on the pedals position and/or orientation. The wireless interface couples the encoder assembly to receive the control signal. The wireless interface also couples the surgical footswitch to a surgical console operable to control and direct surgical equipment. The wireless interface passes the control signal from the encoder to the surgical console, which then directs the surgical equipment based on the control signal. This wireless interface eliminates the tangle of wires or tethers, which may be a hazard in the surgical theater. The internal power generator translates footswitch movement into stored energy to eliminate potential failures of the footswitch during a procedure and overcome the need to replace batteries within the footswitch.

    摘要翻译： 本发明提供了一种手术脚踏开关，其包括底座，踏板，编码器组件，无线接口和内部发电机。 踏板安装在底座上并枢转。 编码器组件耦合到踏板。 当踏板枢转时，编码器组件基于踏板位置和/或方向将踏板的机械信号转换为控制信号。 无线接口耦合编码器组件以接收控制信号。 无线接口还将手术脚踏开关连接到可操作以控制和引导手术设备的外科手术台。 无线接口将控制信号从编码器传递到外科控制台，然后控制信号根据控制信号引导外科设备。 这种无线接口消除了电线或绳索的缠结，这可能是外科手术室的危险。 内部发电机将脚踏开关转换为储存的能量，以消除脚踏开关在程序期间的潜在故障，并克服了更换脚踏开关内的电池的需要。

    APPARATUS AND METHOD FOR AUTO-TITRATING A LASER
    97.
    发明申请
    APPARATUS AND METHOD FOR AUTO-TITRATING A LASER 有权
    用于自动投射激光的装置和方法

    公开(公告)号：US20080004609A1

    公开(公告)日：2008-01-03

    申请号：US11768576

    申请日：2007-06-26

    申请人： Christopher Horvath

    发明人： Christopher Horvath

    IPC分类号： A61B18/20

    CPC分类号： A61F9/008 ,  A61F9/00821 ,  A61F9/00823 ,  A61F2009/00863 ,  A61F2009/00868

    摘要： An apparatus and method for auto-titrating a surgical laser are disclosed. One embodiment of the method comprises: providing an algorithm, wherein the algorithm is operable to configure the laser based on one or more user inputs; providing a first user input operable to cause the algorithm to execute and fire the laser in a defined pattern; providing a second user input, in response to an observed condition, operable to cause the laser to stop firing and to cause the algorithm to determine one or more laser parameter values and configure the laser based on the one or more laser parameter values, wherein a final laser power value when the laser stops firing is an input to the algorithm and wherein the algorithm determines the one or more laser parameters based on the final laser power value. The method can further comprise placing the laser in a “ready” (surgical) mode, either automatically by the auto-titration algorithm or via another user input. Once in a ready mode, a user, such as a surgeon, can perform a surgical procedure with the automatically configured laser. The user inputs can be provided by activating a control switch, such as the footswitch typically used by ophthalmic surgeons to control the operation of an ophthalmic surgical laser.

    摘要翻译： 公开了一种用于自动滴定手术激光的装置和方法。 该方法的一个实施例包括：提供一种算法，其中该算法可操作以基于一个或多个用户输入来配置激光; 提供第一用户输入，其可操作以使所述算法以限定的模式执行和激发所述激光; 提供响应于观察条件的第二用户输入，其可操作以使激光停止点火，并使算法确定一个或多个激光参数值，并且基于一个或多个激光参数值配置激光，其中a 当激光停止点火时的最终激光功率值是算法的输入，并且其中该算法基于最终的激光功率值确定一个或多个激光参数。 该方法还可以包括通过自动滴定算法或通过另一用户输入自动地将激光置于“准备”（外科）模式。 一旦处于就绪模式，用户（例如外科医生）可以用自动配置的激光器执行外科手术。 用户输入可以通过激活控制开关来提供，例如通常由眼科医生使用的脚踏开关来控制眼科手术激光器的操作。

    Method of inhibiting stenosis and restenosis
    99.
    发明申请
    Method of inhibiting stenosis and restenosis 审中-公开
    抑制狭窄和再狭窄的方法

    公开(公告)号：US20050214299A1

    公开(公告)日：2005-09-29

    申请号：US10662061

    申请日：2003-09-12

    申请人： Christopher Horvath ,  Patricia Rao

    发明人： Christopher Horvath ,  Patricia Rao

    IPC分类号： A61K45/06 ,  A61K39/395 ,  A61M29/02 ,  A61M31/00 ,  A61P9/10 ,  A61P9/14 ,  C07K16/28 ,  C07K16/36

    CPC分类号： C07K16/2866 ,  A61K2039/505 ,  A61M25/104 ,  C07K16/2845 ,  C07K2317/24 ,  C07K2317/76 ,  C07K2319/00

    摘要： The invention relates to a method of inhibiting stenosis or restenosis in a subject. In one embodiment, an agent which inhibits recruitment and/or adhesion of neutrophils and mononuclear cells to a site of vascular injury is administered to a subject in need thereof. In another embodiment, a first agent which inhibits recruitment and/or adhesion of neutrophils to a site of vascular injury, and a second agent which inhibits recruitment and/or adhesion of mononuclear cells to a site of vascular injury are administered to a subject in need thereof. In particular embodiments, the agents are antibodies or antigen-binding fragments thereof which bind to CD18 or CCR2.

    摘要翻译： 本发明涉及一种抑制受试者狭窄或再狭窄的方法。 在一个实施方案中，向有需要的受试者施用抑制嗜中性粒细胞和单核细胞向血管损伤部位的募集和/或粘附的药剂。 在另一个实施方案中，将抑制嗜中性粒细胞募集和/或粘附到血管损伤部位的第一药剂和抑制单核细胞募集和/或粘附到血管损伤部位的第二药剂施用于需要的受试者 其中。 在具体实施方案中，所述试剂是结合CD18或CCR2的抗体或其抗原结合片段。