公开(公告)号：US10722161B2

公开(公告)日：2020-07-28

申请号：US13836260

申请日：2013-03-15

Applicant: DexCom, Inc.

Inventor： Naresh C. Bhavaraju ,  Sebastian Bohm ,  Robert J. Boock ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/00 ,  A61B5/1495 ,  A61B5/1473 ,  A61B5/1459 ,  A61B5/145 ,  A61B5/1486

Abstract: Disclosed herein are devices, systems, and methods for a continuous analyte sensor, such as a continuous glucose sensor. In certain embodiments disclosed herein, various in vivo properties of the sensor's surroundings can be measured. In some embodiments, the measured properties can be used to identify a physiological response or condition in the body. This information can then be used by a patient, doctor, or system to respond appropriately to the identified condition.

公开(公告)号：US20200209179A1

公开(公告)日：2020-07-02

申请号：US16729021

申请日：2019-12-27

Applicant: DexCom, Inc.

Inventor： Sebastian Bohm ,  Anna Claire Harley-Trochimczyk ,  Daiting Rong ,  Rui Ma ,  Wenjie Lan ,  Minglian Shi ,  Disha B. Sheth ,  Vincent P. Crabtree ,  Kamuran Turksoy

IPC: G01N27/24 ,  A61B5/145 ,  A61B5/00 ,  G01N27/22

Abstract: Various examples described herein are directed to systems and methods of detecting damage to an analyte sensor using analyte sensor impedance values. In some examples, a method of assessing sensor membrane integrity using sensor electronics comprises determining an impedance parameter of an analyte sensor and determining a membrane integrity state of the analyte sensor based on the impedance parameter.

公开(公告)号：US20200205702A1

公开(公告)日：2020-07-02

申请号：US16728765

申请日：2019-12-27

Applicant: DexCom, Inc.

Inventor： Sebastian Bohm ,  Anna Claire Harley-Trochimczyk ,  Daiting Rong ,  Rui Ma ,  Wenjie Lan ,  Minglian Shi ,  Disha B. Sheth ,  Nicholas Kalfas ,  Vincent P. Crabtree ,  Kamuran Turksoy

IPC: A61B5/1495 ,  A61B5/1486

Abstract: Various examples are directed to systems and methods of and using analyte sensors. An example analyte sensor system comprises an analyte sensor and a hardware device in communication with the analyte sensor. The hardware device may be configured to perform operations comprising applying a first bias voltage to the analyte sensor, the first bias voltage less than an operational bias voltage of the analyte sensor, measuring a first current at the analyte sensor when the first bias voltage is applied, and applying a second bias voltage to the analyte sensor. The operations may further comprise measuring a second current at the analyte sensor when the second bias voltage is applied, detecting a plateau bias voltage using the first current and the second current, determining that the plateau bias voltage is less than a plateau bias voltage threshold, and executing a responsive action at the analyte sensor.

公开(公告)号：US10687740B2

公开(公告)日：2020-06-23

申请号：US16259930

申请日：2019-01-28

Applicant: DexCom, Inc.

Inventor： Sebastian Bohm ,  Mark Dervaes ,  Eric Johnson ,  Apurv Ullas Kamath ,  Shawn Larvenz ,  Jacob S. Leach ,  Phong Lieu ,  Aarthi Mahalingam ,  Tom Miller ,  Paul V. Neale ,  Jack Pryor ,  Thomas A. Peyser ,  Daiting Rong ,  Kenneth San Vicente ,  Mohammad Ali Shariati ,  Peter C. Simpson ,  Matthew Wightlin

IPC: A61B5/145 ,  G06F1/3203 ,  A61B5/1468 ,  A61B5/1486

Abstract: The present invention relates generally to systems and methods for processing, transmitting, and displaying data received from continuous analyte sensor, such as a glucose sensor. In some embodiments, the continuous analyte sensor system comprises a sensor electronics module that includes power saving features. One feature includes a low power measurement circuit that can be switched between a measurement mode and a low power mode, in which charging circuitry continues to apply power to electrodes of a sensor during the low power mode. In addition, the sensor electronics module can be switched between in a low power storage mode higher power operational mode via a switch. The switch can include a reed switch or optical switch, for example. A validation routine can also be implemented to ensure an interrupt signal sent from the switch is valid. The continuous analyte sensor can be physically connected to a sensor electronics module, which is in direct wireless communication with a plurality of different display devices.

公开(公告)号：US20200037938A1

公开(公告)日：2020-02-06

申请号：US16596579

申请日：2019-10-08

Applicant: DexCom, Inc.

Inventor： Daiting Rong ,  Sebastian Böhm ,  Matthew D. Wightlin

IPC: A61B5/145 ,  A61B5/1486

Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes an electrochemical sensor incorporating a silver/silver chloride reference electrode, wherein a capacity of the reference electrode is controlled.

公开(公告)号：US20190320948A1

公开(公告)日：2019-10-24

申请号：US16460906

申请日：2019-07-02

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  G01N33/49 ,  A61B5/1486 ,  A61B5/145 ,  A61B5/00 ,  A61B5/1473 ,  G01N27/02 ,  G01N27/327 ,  G01D18/00

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20190282143A1

公开(公告)日：2019-09-19

申请号：US16431607

申请日：2019-06-04

Applicant: DexCom, Inc.

Inventor： Apurv Ullas Kamath ,  Jacob S. Leach ,  Ying Li ,  Daiting Rong ,  Sean Saint ,  Peter C. Simpson ,  Mark Brister

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/1486 ,  A61B5/1495 ,  C12Q1/00 ,  A61B5/1473

Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

公开(公告)号：US20190261903A1

公开(公告)日：2019-08-29

申请号：US16405931

申请日：2019-05-07

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  G01N33/49 ,  A61B5/145 ,  G01D18/00 ,  G01N27/327 ,  G01N27/02 ,  A61B5/1486 ,  A61B5/00 ,  A61B5/1473

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20180279928A1

公开(公告)日：2018-10-04

申请号：US15994905

申请日：2018-05-31

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  A61B5/1486 ,  A61B5/145 ,  A61B5/00 ,  G01D18/00 ,  G01N27/02 ,  G01N27/327 ,  G01N33/49 ,  A61B5/1473

CPC classification number: A61B5/1495 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/7257 ,  A61B5/7267 ,  A61B2560/0276 ,  G01D18/00 ,  G01N27/026 ,  G01N27/3274 ,  G01N33/49 ,  H05K999/00 ,  H05K999/99

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.

公开(公告)号：US20160198986A1

公开(公告)日：2016-07-14

申请号：US14956170

申请日：2015-12-01

Applicant: DexCom, Inc.

Inventor： Sebastian Böhm ,  Daiting Rong ,  Peter C. Simpson

IPC: A61B5/1495 ,  A61B5/145 ,  A61B5/00

CPC classification number: A61B5/1495 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14517 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/7257 ,  A61B5/7267 ,  A61B2560/0276 ,  G01D18/00 ,  G01N27/026 ,  G01N27/3274 ,  G01N33/49 ,  H05K999/00 ,  H05K999/99

Abstract: Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.