Blocked polymeric particles having internal pore networks for delivering
active substances to selected environments
    91.
    发明授权
    Blocked polymeric particles having internal pore networks for delivering active substances to selected environments 失效
    封闭的聚合物颗粒具有用于将活性物质输送到选定环境的内孔网络

    公开(公告)号:US5316774A

    公开(公告)日:1994-05-31

    申请号:US806860

    申请日:1991-12-09

    CPC分类号: A61K9/1635 Y10S514/951

    摘要: A composition for the controlled release of an active substance comprises a polymeric particle matrix, where each particle defines a network of internal pores. The active substance is entrapped within the pore network together with a blocking agent having physical and chemical characteristics selected to modify the release rate of the active substance from the internal pore network. In an exemplary embodiment, drugs may be selectively delivered to the intestines using an enteric material as the blocking agent. The enteric material remains intact in the stomach but will degrade under the pH conditions of the intestines. In another exemplary embodiment, the sustained release formulation employs a blocking agent which remains stable under the expected conditions of the environment to which the active substance is to be released.

    摘要翻译: 用于控制释放活性物质的组合物包括聚合物颗粒基质,其中每个颗粒限定内部孔的网络。 活性物质与具有选择的物理和化学特性的封闭剂一起截留在孔网内,以改变活性物质从内部孔网络的释放速率。 在一个示例性实施方案中,药物可以使用肠溶材料作为阻断剂选择性递送至肠。 肠道物质在胃中保持完整,但在肠的pH条件下会降解。 在另一个示例性实施方案中,持续释放制剂采用封闭剂,其在待释放活性物质的环境的预期条件下保持稳定。

    SYSTEM AND METHOD FOR TRIP PLANNING

    公开(公告)号:US20210241395A1

    公开(公告)日:2021-08-05

    申请号:US17222748

    申请日:2021-04-05

    申请人: Rajesh Patel

    发明人: Rajesh Patel

    摘要: A system and method for finding an optimum travel plan for several subsequent destinations. The system can receive several destinations from the user and determine the optimum travel plan. The different destinations can be provided by capturing an address or location from a webpage or uploading an image of the destination.

    IMMINENT COLLISION WARNING SYSTEM AND METHOD
    96.
    发明申请
    IMMINENT COLLISION WARNING SYSTEM AND METHOD 审中-公开
    立即碰撞警告系统和方法

    公开(公告)号:US20110163862A1

    公开(公告)日:2011-07-07

    申请号:US13048070

    申请日:2011-03-15

    IPC分类号: B60Q9/00

    CPC分类号: G08G1/164

    摘要: The invention is directed to methods and systems for sensing the presence of objects in the intended path of an automobile with a system to warn both the operator of the vehicle and the object of regard.

    摘要翻译: 本发明涉及用于感测汽车预期路径中物体的存在的方法和系统,其具有警告车辆的操作者和所关注的对象的系统。