公开(公告)号：US12133978B2

公开(公告)日：2024-11-05

申请号：US18130698

申请日：2023-04-04

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Ehud Schwammenthal ,  Daniel Glozman ,  Gad Lubinksy

IPC: A61M60/833 ,  A61M60/13 ,  A61M60/139 ,  A61M60/216 ,  A61M60/416 ,  A61M60/531 ,  A61M60/585 ,  A61M60/804 ,  A61M60/818 ,  A61M60/414

Abstract: Apparatus and methods are described including a catheter, and first and second impellers configured to be inserted into a subject's body via the catheter, the first and second impellers being disposed in series with each other. A first impeller cage is disposed around the first impeller, and a second impeller cage is disposed around the second impeller. A sleeve extends longitudinally along more than 50 percent of a distance between the first and second impellers. Other applications are also described.

公开(公告)号：US12127820B2

公开(公告)日：2024-10-29

申请号：US16952327

申请日：2020-11-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/00 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/18 ,  F04D29/24

CPC classification number: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/0066 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/181 ,  F04D29/247 ,  A61M2205/0266 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2205/3365 ,  A61M2205/50 ,  A61M2230/04 ,  A61M2230/30

Abstract: Apparatus and methods are described including a left ventricular assist device that includes an impeller configured to be placed inside a left ventricle of a subject and to pump blood from the left ventricle to an aorta of the subject, by rotating. A frame is disposed around the impeller. A tube is configured to traverse an aortic valve of the subject, such that a proximal portion of the tube is disposed within the subject's aorta and a distal portion of the tube is disposed within the subject's left ventricle. The distal portion of the tube extends to a distal end of the frame and defines one or more lateral blood inlet openings that are configured to allow blood to flow from the subject's left ventricle into the tube. Other applications are also described.

公开(公告)号：US20240341943A1

公开(公告)日：2024-10-17

申请号：US18388383

申请日：2023-11-09

Applicant: Magenta Medical Ltd

Inventor： Ehud Schwammenthal ,  Yosi Tuval ,  Daniel Glozman

IPC: A61F2/07 ,  A61B5/0205 ,  A61M60/13 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/33 ,  A61M60/411 ,  A61M60/414 ,  A61M60/422 ,  A61M60/523 ,  A61M60/808 ,  A61M60/81 ,  A61M60/825 ,  A61M60/833 ,  A61M60/861 ,  A61M60/896

CPC classification number: A61F2/07 ,  A61B5/02055 ,  A61M60/13 ,  A61M60/135 ,  A61M60/237 ,  A61M60/33 ,  A61M60/411 ,  A61M60/422 ,  A61M60/523 ,  A61M60/808 ,  A61M60/81 ,  A61M60/825 ,  A61M60/833 ,  A61M60/861 ,  A61M60/148 ,  A61M60/414 ,  A61M60/896 ,  A61M2207/00 ,  A61M2210/1082 ,  A61M2210/12

Abstract: Apparatus and methods are described including an impeller for use in a blood pump. An impeller frame includes proximal and distal end portions and at least one helical elongate element that winds from the proximal end portion to the distal end portion. A material is coupled to the helical elongate element, such that the helical elongate element with the material coupled thereto defines a blade of the impeller. A mediator is coupled to the helical elongate element. The helical elongate element has a first stiffness, the material has a lower stiffness than the first stiffness, and the mediator is configured to enhance bonding between the helical elongate element and the material. Other applications are also described.

公开(公告)号：US20240090780A1

公开(公告)日：2024-03-21

申请号：US18511532

申请日：2023-11-16

Applicant: Magenta Medical Ltd

Inventor： Yosi Tuval ,  Zev SOHN ,  Ehud Schwammenthal ,  Gad Lubinsky

IPC: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/00 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/18 ,  F04D29/24

CPC classification number: A61B5/0215 ,  A61M60/135 ,  A61M60/148 ,  A61M60/237 ,  A61M60/414 ,  A61M60/419 ,  A61M60/422 ,  A61M60/531 ,  A61M60/554 ,  A61M60/818 ,  A61M60/824 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/896 ,  F04D3/02 ,  F04D7/00 ,  F04D15/0066 ,  F04D25/02 ,  F04D29/041 ,  F04D29/042 ,  F04D29/181 ,  F04D29/247 ,  A61M2205/0266 ,  A61M2205/3317 ,  A61M2205/3327 ,  A61M2205/3334 ,  A61M2205/3344 ,  A61M2205/3365 ,  A61M2205/50 ,  A61M2230/04 ,  A61M2230/30

Abstract: Apparatus and methods are described including a ventricular assist device that includes an impeller configured to be placed inside a left ventricle of a subject, and a frame configured to be disposed around the impeller. The frame is shaped such that, in a non-radially constrained configuration of the frame, the frame defines a cylindrical central portion, and a distal conical portion that is disposed distally with respect to the cylindrical central portion and that widens from a distal end of the frame to a distal end of the cylindrical central portion. The frame defines struts that define openings therebetween, and all openings that are defined at least partially within the distal conical portion of the frame extend into the cylindrical central portion of the frame. Other applications are also described.

公开(公告)号：US11648392B2

公开(公告)日：2023-05-16

申请号：US17320742

申请日：2021-05-14

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Ehud Schwammenthal ,  Daniel Glozman ,  Gad Lubinksy

IPC: A61M60/833 ,  A61M60/216 ,  A61M60/416 ,  A61M60/13 ,  A61M60/804 ,  A61M60/818 ,  A61M60/585 ,  A61M60/531 ,  A61M60/139 ,  A61M60/414

CPC classification number: A61M60/833 ,  A61M60/13 ,  A61M60/139 ,  A61M60/216 ,  A61M60/416 ,  A61M60/531 ,  A61M60/585 ,  A61M60/804 ,  A61M60/818 ,  A61M60/414

Abstract: Apparatus and methods are described including a catheter, and first and second impellers configured to be inserted into a subject's body via the catheter, the first and second impellers being disposed in series with each other. A motor is configured to generate rotational motion. A rotation shaft extends from the motor to the first impeller and imparts the rotational motion from the motor to the first impeller. A gear mechanism disposed between the first and second impeller is configured to effect a change in rotational motion that is imparted from the first impeller to the second impeller, such that the second impeller rotates in a different manner from the first impeller. Other applications are also described.

公开(公告)号：US20220355096A1

公开(公告)日：2022-11-10

申请号：US17857402

申请日：2022-07-05

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/419 ,  A61M60/422 ,  A61M60/829 ,  A61M60/857 ,  A61M60/896 ,  A61M60/414 ,  F04D29/52 ,  F04D29/54 ,  F04D29/38 ,  B05D1/02 ,  A61M60/808 ,  A61M60/126 ,  A61M60/216 ,  A61M60/237 ,  A61M60/825 ,  A61M60/531 ,  A61M60/13 ,  A61M60/894

Abstract: Apparatus and methods are described including a blood pump that includes an impeller configured to pump blood through a subject's body, and a frame disposed around the impeller. In a radially-non-constrained configuration of the frame, the frame defines a proximal conical portion and a cylindrical portion disposed distally to the proximal conical portion. During operation of the blood pump, the impeller moves with respect to the frame, and a range of movement of the impeller is such that at least a first portion of the impeller is disposed within the proximal conical portion of the frame during at least some of the operation of the blood pump, and at least a second portion of the impeller is disposed within the cylindrical portion of the frame during at least some of the operation of the blood pump. Other applications are also described.

公开(公告)号：US20220241576A1

公开(公告)日：2022-08-04

申请号：US17723656

申请日：2022-04-19

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Jacob Leisner Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/419 ,  A61M60/422 ,  A61M60/818 ,  A61M60/829 ,  A61M60/857 ,  A61M60/896 ,  A61M60/414 ,  A61M60/135 ,  F04D29/52 ,  F04D29/54 ,  F04D29/38 ,  B05D1/02 ,  A61M60/808 ,  A61M60/126 ,  A61M60/216

Abstract: Apparatus and methods are described including delivering a left-ventricular assist device to a subject's left ventricle. A tube is positioned such that a proximal portion of the tube traverses an aortic valve of the subject, and a distal portion of the tube is disposed within a left ventricle of the subject. A pump pumps blood through the tube from the subject's left ventricle to the subject's aorta. A curved element is disposed within the tube and is configured to cause at least a portion of the tube to become curved. Other applications are also described.

公开(公告)号：US20220241574A1

公开(公告)日：2022-08-04

申请号：US17722752

申请日：2022-04-18

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Jacob Leisner Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/419 ,  A61M60/422 ,  A61M60/818 ,  A61M60/829 ,  A61M60/857 ,  A61M60/896 ,  A61M60/414 ,  A61M60/135 ,  F04D29/52 ,  F04D29/54 ,  F04D29/38 ,  B05D1/02 ,  A61M60/808 ,  A61M60/126 ,  A61M60/216

Abstract: Apparatus and methods are described including delivering a left-ventricular assist device to a subject's aorta. The device including a distal-tip element that defines a straight proximal portion, and a curved distal portion, the curved distal portion defining first and second curves with an elongated straight portion between the first and second curves. The distal-tip element is centered with respect to the aortic valve using the curved distal portion of the distal-tip element, to thereby guide the device through the subject's aortic valve atraumatically. A pump pumps blood through from the subject's left ventricle to the subject's aorta. Other applications are also described.

公开(公告)号：US20220176098A1

公开(公告)日：2022-06-09

申请号：US17677571

申请日：2022-02-22

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M60/148 ,  A61M60/419 ,  A61M60/422 ,  A61M60/818 ,  A61M60/829 ,  A61M60/857 ,  A61M60/896 ,  A61M60/414 ,  A61M60/135 ,  F04D29/52 ,  F04D29/54 ,  F04D29/38

Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a tube configured to traverse a subject's aortic valve, with a distal portion of the tube within the subject's left ventricle. A frame disposed within the distal portion of the tube defines cells, and a width of each of the cells within a generally cylindrical portion of the frame is less than 2 mm. An inner lining lines at least some of the cylindrical portion of the frame. An impeller is disposed inside the frame. Other applications are also described.

公开(公告)号：US11298523B2

公开(公告)日：2022-04-12

申请号：US16810172

申请日：2020-03-05

Applicant: Magenta Medical Ltd.

Inventor： Yosi Tuval ,  Zev Sohn ,  Ehud Schwammenthal ,  Gad Lubinsky ,  Victor Troshin ,  Shaul Mustacchi ,  Yinnon Elisha ,  Yuri Sudin ,  Hagit Zemer Harel ,  Avi Rozenfeld

IPC: A61M1/12 ,  A61M1/10 ,  A61M60/148 ,  A61M60/419 ,  A61M60/422 ,  A61M60/818 ,  A61M60/829 ,  A61M60/857 ,  A61M60/896 ,  A61M60/414 ,  A61M60/135 ,  F04D29/52 ,  F04D29/54 ,  F04D29/38 ,  A61M60/205 ,  A61M60/122

Abstract: Apparatus and methods are described including manufacturing a housing for an impeller of a blood pump by placing an inner lining around a mandrel, placing a cylindrical portion of a frame around the inner lining, and placing a distal portion of an elongate tube around a portion of the frame. While the distal portion of the elongate tube is disposed around the portion of the frame, the inner lining, the frame, and the distal portion of the elongate tube are heated, via the mandrel, and pressure is applied from outside the distal portion of the elongate tube, such as to cause the distal portion of the elongate tube to conform with a structure of the struts of the frame, and to cause the inner lining and the distal portion of the elongate tube to become coupled to the frame. Other applications are also described.