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公开(公告)号：US20130165988A1
公开(公告)日：2013-06-27
申请号：US13706498
申请日：2012-12-06
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh
IPC: A61N1/37
CPC classification number: A61N1/3712 , A61B5/0006 , A61B5/0422 , A61B5/04525 , A61B5/0464 , A61N1/3684
Abstract: A method for monitoring the effectiveness of VSR and for taking action to improve the effectiveness of VSRs, if they are determined to be ineffective, includes comparing the a VSR evoked electrogram to a template electrogram of a pure biventricular paced CRT beat. If the electrograms, or features thereof, are similar, the VSR is determined to be effective. If the VSR is determined to be ineffective, the AV delay of biventricular CRT is shortened in a step-wise fashion in an incremental manner.
Abstract translation: 监测VSR的有效性和采取行动以提高VSR的有效性的方法（如果确定为无效的）包括将VSR诱发电描记图与纯双心室起搏CRT搏击的模板电描记比较。 如果电描记图或其特征相似，则确定VSR是有效的。 如果VSR被确定为无效，则双向CRT的AV延迟以逐步方式逐渐缩短。
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公开(公告)号：US20250114618A1
公开(公告)日：2025-04-10
申请号：US18987742
申请日：2024-12-19
Applicant: MEDTRONIC, INC.
Inventor： Subham Ghosh
Abstract: Ventricle-from-atrium (VfA) cardiac therapy may utilize a tissue-piercing electrode implanted in the left ventricular myocardium of the patient's heart from the right atrium through the right atrial endocardium and central fibrous body. The exemplary devices and methods may determine whether the tissue-piercing electrode is achieving effective left ventricular capture. Additionally, one or more pacing parameters, or paced settings, may be adjusted in view of the effective left ventricular capture determination.
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公开(公告)号：US11944461B2
公开(公告)日：2024-04-02
申请号：US17107551
申请日：2020-11-30
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh , Karen J. Kleckner , Marc C. Steckler , Trent M. Fischer , Daniel S. Flo
IPC: A61B5/35 , A61B5/00 , A61B5/364 , A61B5/367 , G16H40/67 , G16H50/30 , A61B5/256 , A61B5/257 , A61B5/341 , A61N1/365
CPC classification number: A61B5/7221 , A61B5/35 , A61B5/364 , A61B5/367 , A61B5/7203 , G16H40/67 , G16H50/30 , A61B5/256 , A61B5/257 , A61B5/341 , A61N1/36507
Abstract: Systems and methods are described herein for generating representative cardiac information. The representative cardiac information may be based on a plurality of electrode signals monitored, or measured, over a plurality of cardiac cycles or heart beats. The systems and methods may remove unqualified cardiac cycles, remove invalid electrode signals, remove inconsistent cardiac cycles, and removing uncorrelated cardiac cycles, and then generate representative cardiac information based on the remaining cardiac cycles and electrode signals.
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公开(公告)号：US11801390B2
公开(公告)日：2023-10-31
申请号：US16001453
申请日：2018-06-06
Applicant: Medtronic, Inc.
Inventor： Robert W. Stadler , Ruth N. Klepfer , Subham Ghosh , Yanina Grinberg
CPC classification number: A61N1/37252 , A61N1/36585 , A61B5/721 , A61N1/368 , A61N1/36542
Abstract: An implantable medical device system and method for delivering cardiac resynchronization therapy (CRT) pacing that includes determining capture associated with the delivered CRT pacing is ineffective in response to the delivered CRT pacing. A reason for capture being ineffective is determined and a safety margin is adjusted if the determined reason for capture being ineffective is loss of capture and a left ventricle (LV) pre-excitation is adjusted if the determined reason for capture being ineffective is delayed LV depolarization. Monitoring for a change in effective cardiac resynchronization therapy is used to confirm that the adjustment of the CRT pacing was effective in resolving the ineffective capture.
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公开(公告)号：US11752347B2
公开(公告)日：2023-09-12
申请号：US17360648
申请日：2021-06-28
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh
CPC classification number: A61N1/3682 , A61N1/3688 , A61N1/3706 , A61N1/37512 , A61N1/39622
Abstract: The present disclosure relates generally to pacing of the cardiac conduction system of a patient, and more particularly, to providing adaptive cardiac conducting system pacing therapy and to determining selective or non-selective capture of the cardiac conduction system by cardiac conduction system pacing therapy. The adaptive cardiac conduction system pacing therapy may adjust AV delay and VV delay based on various signals and metrics and may switch between cardiac conduction system pacing therapy exclusively and cardiac conduction system pacing therapy in combination with traditional left ventricular pacing therapy.
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Patent Agency Ranking
公开(公告)号：US11701517B2
公开(公告)日：2023-07-18
申请号：US16793193
申请日：2020-02-18
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh
CPC classification number: A61N1/36585 , A61N1/368 , A61N1/3624 , A61N1/36578 , A61N1/3706 , A61N1/3937 , A61N1/3956
Abstract: An implantable medical device includes a plurality of electrodes to detect electrical activity, a motion detector to detect mechanical activity, and a controller to determine at least one electromechanical interval based on at least one of electrical activity and mechanical activity. The activity detected may be in response to delivering a pacing pulse according to an atrioventricular (AV) pacing interval using the second electrode. The electromechanical interval may be used to adjust the AV pacing interval. The electromechanical interval may be used to determine whether cardiac therapy is acceptable or whether atrial or ventricular remodeling is successful.
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公开(公告)号：US11648406B2
公开(公告)日：2023-05-16
申请号：US15920080
申请日：2018-03-13
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh , Jeffrey Gillberg
CPC classification number: A61N1/37247 , A61B5/339 , A61N1/371
Abstract: Systems, methods, and interfaces are described herein for identification of effective electrodes to be used in sensing and/or therapy. Two or more portions of a signal monitored using an electrode may be compared to determine whether the electrode is effective. The two or more portions may correspond to the same portion or window of a cardiac cycle. Further, signals from a first electrode and from a second electrode located proximate the first electrode may be compared to determine whether one or both of the electrodes are effective.
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公开(公告)号：US11497431B2
公开(公告)日：2022-11-15
申请号：US17031189
申请日：2020-09-24
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh
Abstract: Systems and methods are described herein for evaluation and configuration cardiac therapy. The systems and methods may monitor electrical activity using a plurality of external electrodes and may utilize multiple-electrode cardiac metrics such as electrical heterogeneity information, single-electrode cardiac metrics, and vectorcardiographic metrics to determine and select one or more paced settings from a plurality of different paced settings.
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公开(公告)号：US11285312B2
公开(公告)日：2022-03-29
申请号：US16369913
申请日：2019-03-29
Applicant: Medtronic, Inc.
Inventor： Jeffrey M. Gillberg , Subham Ghosh , Michael F. Hess , Troy E. Jackson
IPC: A61M1/10 , A61M1/12 , A61B5/0408 , A61B5/00 , A61M60/50 , A61N1/362 , A61B5/25 , A61B5/282 , A61M60/148 , A61N1/368 , A61B5/339 , A61B5/349
Abstract: Systems and methods are described herein for evaluation and adjustment of a left ventricular assist device (LVAD). The systems and methods may utilize at least a plurality of external electrodes to monitor cardiac electrical activity before and during LVAD therapy. The cardiac electrical activity as well as other information such cardiac sound information may be used to determine and adjust one or more LVAD output parameters such as pump speed.
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公开(公告)号：US20220032070A1
公开(公告)日：2022-02-03
申请号：US17361721
申请日：2021-06-29
Applicant: Medtronic, Inc.
Inventor： Ruth N. Klepfer , Manfred Justen , Subham Ghosh , Jeffrey M. Gillberg
Abstract: Systems, interfaces, and methods are described herein related to the evaluation of a patient's cardiac conduction system and evaluation of cardiac conduction system pacing therapy being delivered to the patient's cardiac conduction system. Evaluation of the patient's cardiac conduction system may utilize a plurality of breakthrough maps to determine where a cardiac conduction system block may be located. Evaluation of cardiac conduction system pacing therapy may utilize various electrical heterogeneity information monitored before and during delivery of cardiac conduction system pacing therapy.
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