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112 条记录 (耗时 0.05 秒)

    System and Method to Modulate Phrenic Nerve to Prevent Sleep Apnea
    91.
    发明申请
    System and Method to Modulate Phrenic Nerve to Prevent Sleep Apnea 审中-公开
    调节膈神经以防止睡眠呼吸暂停的系统和方法

    公开(公告)号：US20130165989A1

    公开(公告)日：2013-06-27

    申请号：US13538713

    申请日：2012-06-29

    申请人： Mark Gelfand ,  Howard R. Levin ,  Andrew Halpert

    发明人： Mark Gelfand ,  Howard R. Levin ,  Andrew Halpert

    IPC分类号： A61N1/36

    CPC分类号： A61N1/3611 ,  A61N1/0551 ,  A61N1/3601 ,  A61N1/36135

    摘要： An implantable medical device for treating breathing disorders such as central sleep apnea wherein stimulation is provided to the phrenic never through a transvenous lead system with the stimulation beginning after inspiration to extend the duration of a breath and to hold the diaphragm in a contracted condition.

    摘要翻译： 一种用于治疗诸如中枢性睡眠呼吸暂停的呼吸障碍的可植入医疗装置，其中刺激从未通过经静脉引导系统提供给膈肌，刺激开始于吸气之后，以延长呼吸持续时间并将隔膜保持在收缩状态。

    HIGH INTENSITY FOCUSED ULTRASOUND CATHETER APPARATUSES, SYSTEMS, AND METHODS FOR RENAL NEUROMODULATION
    92.
    发明申请
    HIGH INTENSITY FOCUSED ULTRASOUND CATHETER APPARATUSES, SYSTEMS, AND METHODS FOR RENAL NEUROMODULATION 审中-公开
    高强度聚焦超声波导管器械，系统和方法用于肾神经修复

    公开(公告)号：US20110112400A1

    公开(公告)日：2011-05-12

    申请号：US12940922

    申请日：2010-11-05

    申请人： Charles D. Emery ,  Mark Gelfand ,  Howard R. Levin ,  Denise Zarins

    发明人： Charles D. Emery ,  Mark Gelfand ,  Howard R. Levin ,  Denise Zarins

    IPC分类号： A61N7/02 ,  A61N7/00 ,  A61B8/12

    CPC分类号： A61N7/022 ,  A61B8/12 ,  A61B8/445 ,  A61B8/485 ,  A61B2018/00029 ,  A61B2090/3782 ,  A61N7/00 ,  A61N2007/0026 ,  A61N2007/0056 ,  A61N2007/0078 ,  A61N2007/027

    摘要： Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device that employs high intensity focused ultrasound. The high intensity focused ultrasound may be used for application of energy to modulate neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. The ultrasound transducer for delivering the energy may be located remotely from the desired treatment area. In particular embodiments, an ultrasound transducer may apply energy at one or more focal zones or focal points that target renal nerves.

    摘要翻译： 本文公开了通过血管内通路实现肾脏神经调节的导管装置，系统和方法。 本申请的一个方面，例如涉及包含使用高强度聚焦超声的导管治疗装置的装置，系统和方法。 高强度聚焦超声可用于施加能量以调节有助于肾功能的神经纤维，或用于饲养或灌注神经纤维的血管结构。 用于传送能量的超声换能器可以远离所需的治疗区域。 在特定实施例中，超声换能器可以在靶向肾神经的一个或多个焦点区域或焦点处施加能量。

    Patient hydration system with a redundant monitoring of hydration fluid infusion
    94.
    发明授权
    Patient hydration system with a redundant monitoring of hydration fluid infusion 有权
    患者水合系统具有水化液输液的冗余监测

    公开(公告)号：US07758562B2

    公开(公告)日：2010-07-20

    申请号：US11408851

    申请日：2006-04-21

    申请人： Mark Gelfand ,  Howard R. Levin

    发明人： Mark Gelfand ,  Howard R. Levin

    IPC分类号： A61M31/00 ,  A61M1/00

    CPC分类号： A61M5/1723 ,  A61B5/201 ,  A61B5/208 ,  A61B5/4839 ,  A61M5/007 ,  A61M5/142 ,  A61M5/16895 ,  A61M5/365 ,  A61M2205/18 ,  A61M2205/3355 ,  A61M2205/3393 ,  G01G17/04

    摘要： A patient hydration system including an infusion device for administering hydration fluid to a patient, and a hydration fluid measurement device responsive to a source of hydration fluid, a patient urine output measurement device. A controller is responsive to the hydration fluid measurement device and the patient urine output measurement device. The controller operates the infusion device, in response to the patient urine output measurement device and the hydration fluid measurement device, to hydrate the patient based on the patient's urine output. The controller also monitors the operation history of the infusion device thereby providing redundancy in the measurement of the amount of hydration fluid administered to the patient.

    摘要翻译： 一种患者水合系统，包括用于向患者施用水合流体的输注装置，以及响应于水合流体源的水合流体测量装置，患者尿液输出测量装置。 控制器响应于水合流体测量装置和患者尿液输出测量装置。 控制器响应于患者尿液输出测量装置和水合流体测量装置操作输液装置，以基于患者的尿液输出水合患者。 控制器还监测输注装置的操作历史，从而在测量给予患者的水合液量的量方面提供冗余。

    Method and apparatus for peripheral vein fluid removal in heart failure
    98.
    发明授权
    Method and apparatus for peripheral vein fluid removal in heart failure 有权
    心力衰竭中外周静脉血液清除的方法和装置

    公开(公告)号：US07311689B2

    公开(公告)日：2007-12-25

    申请号：US10642638

    申请日：2003-08-19

    申请人： Howard R. Levin ,  Mark Gelfand ,  John O'Mahony ,  Hans-Dietrich Polaschegg

    发明人： Howard R. Levin ,  Mark Gelfand ,  John O'Mahony ,  Hans-Dietrich Polaschegg

    IPC分类号： A67M37/00 ,  C02F1/44

    CPC分类号： A61M1/341 ,  A61M1/1692 ,  A61M1/34 ,  A61M1/361 ,  A61M1/3612 ,  A61M2205/3393 ,  A61M2205/50 ,  A61M2205/7563

    摘要： A method and apparatus for ultrafiltration of blood operating by removing blood from a peripheral blood vessel at a rate of less than two percent of total cardiac output of a patient, extracting fluid at a rate of 0.1 liter to 1.0 liters per hour while retaining cells and proteins in the blood, and returning the concentrated blood to a secondary blood vessel is disclosed. Blood is removed and returned using small gage needles. As a pump circulates blood from the patient, a filter removes ultrafiltrate from the blood using duty cycle or pump control, and a transparent container collects the removed fluid.

    摘要翻译： 一种通过以小于患者总心输出量的百分之二的速率从外周血管中除血的血液超滤操作的方法和装置，以每小时0.1升至1.0升的速率提取液体，同时保留细胞和 公开了血液中的蛋白质，并将浓缩血液返回到二次血管。 使用小规格针头取出血液并返回。 当泵从患者循环血液时，过滤器使用占空比或泵控制从血液中除去超滤液，并且透明容器收集去除的流体。

    Method and apparatus for ultrafiltration utilizing a long peripheral access venous cannula for blood withdrawal
    99.
    发明授权
    Method and apparatus for ultrafiltration utilizing a long peripheral access venous cannula for blood withdrawal 有权
    用于超滤的方法和装置，其利用长周边通路静脉插管进行抽血

    公开(公告)号：US06685664B2

    公开(公告)日：2004-02-03

    申请号：US09876185

    申请日：2001-06-08

    申请人： Howard R. Levin ,  Mark Gelfand ,  Steve Bernard

    发明人： Howard R. Levin ,  Mark Gelfand ,  Steve Bernard

    IPC分类号： A61M3700

    CPC分类号： A61M1/34 ,  A61M1/36 ,  A61M25/0014 ,  A61M2205/15 ,  A61M2205/502

    摘要： Method and apparatus for the extracorporeal treatment of blood by utilizing a peripherally inserted catheter assembly for the continuous removal of blood for renal replacement treatment, in particularly, treatment of congestive heart failure and fluid overload by ultrafiltration. A catheter is inserted in a peripheral vein and maneuvered upward through the vascular system to access the reservoir of blood in the large or great veins for continuous blood withdrawal and treatment. Air-tight connectors are incorporated in the catheter assembly to overcome the untoward effects of negative pressure in blood withdrawal.

    摘要翻译： 通过利用外周插入的导管组件连续去除血液进行肾脏替代治疗，特别是通过超滤治疗充血性心力衰竭和流体过载来体外治疗血液的方法和装置。 将导管插入外周静脉，并通过血管系统向上操作，以进入大静脉中的血液储存器，用于持续取血和治疗。 气密连接器被结合在导管组件中以克服抽血中负压的不利影响。

    Method and apparatus for treatment of congestive heart failure by improving perfusion of the kidney by infusion of a vasodilator
    100.
    发明授权
    Method and apparatus for treatment of congestive heart failure by improving perfusion of the kidney by infusion of a vasodilator 有权
    通过输注血管扩张剂改善肾脏灌注来治疗充血性心力衰竭的方法和装置

    公开(公告)号：US06287608B1

    公开(公告)日：2001-09-11

    申请号：US09547104

    申请日：2000-04-11

    申请人： Howard R. Levin ,  Mark Gelfand

    发明人： Howard R. Levin ,  Mark Gelfand

    IPC分类号： A61K3300

    CPC分类号： A61K33/00

    摘要： A method for treating congestive heart failure (CHF) has been developed that restores kidney renal functions by artificial vasodilation of at least one kidney. A vasodilator drug is locally delivered to the kidney via a kidney perfusion catheter. The drug can be mixed with the patient's blood, saline or other suitable solvent and the mixture directly applied to the kidney through the catheter. The restoration of kidney function assists the heart by removing excess fluid, urine and toxin from the patient, and by normalizing the patient's renin-angiotensin system and other neurohormonal substances. The method is applicable to treat chronic and acute CHF.

    摘要翻译： 已经开发了治疗充血性心力衰竭（CHF）的方法，其通过至少一个肾脏的人造血管舒张来恢复肾脏肾功能。 血管扩张剂药物通过肾脏灌注导管局部递送至肾脏。 药物可以与患者的血液，盐水或其他合适的溶剂混合，混合物通过导管直接施用于肾脏。 肾功能的恢复通过从病人身上清除多余的液体，尿液和毒素，以及使患者的肾素 - 血管紧张素系统和其他神经激素物质正常化来帮助心脏。 该方法适用于慢性和急性CHF。