摘要:
Cardioprotective pacing is applied to prevent and/or reduce cardiac injury associated with myocardial infarction (MI) and revascularization procedure. Pacing pulses are generated from a pacemaker and delivered through pacing electrodes incorporated onto percutaneous transluminal vascular intervention (PTVI) devices during the revascularization procedure. Examples of the PTVI devices include a guide catheter, a guide wire, and an angioplasty catheter such as a balloon catheter used in the revascularization procedure. The pacing electrodes are incorporated onto such PTVI devices in various ways.
摘要:
Catheter devices having an expandable balloon for delivering a therapeutic agent to a body site. In one aspect, one or more sheaths are disposed around the balloon with the therapeutic agent being disposed within the sheath, being disposed over the sheath, being contained in the space between the sheath and the balloon, or being otherwise associated with the sheath. In another aspect, the balloon includes a micro-electromechanical system (MEMS) for drug delivery.
摘要:
A device for sealing a puncture opening in a wall of a blood vessel may include a base frame including a first bi-stable material having a first stable state corresponding to a delivery configuration of the base frame, in which the base frame is retracted to have a relatively smaller overall profile, and a second stable state corresponding to a deployed configuration of the base frame, in which the base frame is extended to have a relatively larger overall profile. The base frame is sized to engage an interior surface of the blood vessel wall when in the deployed configuration. A sealing section is coupled to the base frame and includes a second bi-stable material having a first stable state corresponding to an initial configuration of the sealing section, in which the sealing section permits fluid flow, and a second stable state corresponding to a barrier configuration of the sealing section, in which the sealing section prevents fluid flow. The sealing section in the barrier configuration is sized to block fluid flow through the puncture opening when the base frame is in the deployed configuration.
摘要:
The invention is directed to mechanisms and methods that reduce the delamination of a therapeutic agent from a stent. The mechanisms include holes (channels, wells, and other hole configurations), protrusions, sintered metal cores, clamps/staples, pins, and stainless steel shields.
摘要:
An expandable stent for percutaneous procedures comprises a tubular structure disposed about a longitudinal axis and a plurality of fingers. The plurality of fingers, upon expansion of the stent, extends from the tubular structure about a second longitudinal axis which is angularly offset from the first longitudinal axis. At least one of the plurality of fingers has a length that is greater than that of the other fingers.
摘要:
Medical devices or components thereof having electroactive polymer actuators embedded within at least a portion of the device of component thereof, and novel electroactive polymer actuators formed with a conductive substrate layer and an electroactive polymer layer, the electroactive polymer actuated upon application of a voltage to surrounding liquid electrolyte, the actuators may be embedded within an inert polymer matrix material, or within solid polyelectrolyte matrix material.
摘要:
Devices and methods for transferring forces down a catheter shaft while also maintaining an open fluid pathway are disclosed. In some of the designs, inner and outer members of the catheter interact, allowing improved transfer of forces down the catheter shaft. These designs also allow for maintenance of a fluid pathway along the length of the shaft, including at locations where the inner and outer members are interacting with one another. Structures are disclosed which extend at least a portion of the length of the shaft, allowing improved force transfer and resistance to kinking. Structures are also disclosed which specifically allow for inner and outer members to engage one another at at least one point along the shaft, improving the transfer of forces down the shaft.
摘要:
A catheter tip has an outer surface section, an inner surface section, a spatial configuration and at least one segment of electroactive polymer. The inner surface section defines a guide wire lumen. The electroactive polymer has an actuated state and a non-actuated state. In an actuated state, the electroactive polymer alters the spatial configuration of the catheter tip.
摘要:
Medical devices may include structure or provision that permit a physician or other health care professional to adjust particular parameters such as flexibility, stiffness and compressive strength of at least a portion of the medical device. In some instances, the medical device may be adjusted prior to inserting the medical device into a patient. In some cases, the medical device may be adjusted while in use within the patient.
摘要:
A catheter, for example, a balloon catheter has a first and second section and a transition between the sections. The sections and the transition are arranged to enhance catheter deliverability.