公开(公告)号：US06310216B1

公开(公告)日：2001-10-30

申请号：US09463867

申请日：2000-02-18

申请人： Elmar Vilsmaier ,  Torsten Goerz ,  Gunther Milch ,  Uwe Petersen ,  Axel Dalhoff ,  Gabriele Schmuck

发明人： Elmar Vilsmaier ,  Torsten Goerz ,  Gunther Milch ,  Uwe Petersen ,  Axel Dalhoff ,  Gabriele Schmuck

IPC分类号： C07D20952

CPC分类号： C07D471/14 ,  C07D209/52 ,  Y02P20/55

摘要： 6-Amino-3-azabicyclo[3.1.0]hexanes of the formula wherein R1 and R2 independently of one another are C3-C4-alkenyl or Ar—CH(R′)— where R′ is hydrogen or C1-C4-alkyl and Ar is an optionally substituted C6-C10-aryl and R3 is hydrogen, C3-C4-alkenyl, Ar—CH(R′)— where R′ is hydrogen or C1-C4-alkyl and Ar is an optionally substituted C6-C10-aryl or COOR4 where R4 is C1-C4-alkyl or C2-C4-alkenyl. The invention also relates to a method for making these compounds and a method for using them.

摘要翻译： 式R 1和R 2彼此独立的6-氨基-3-氮杂双环[3.1.0]己烷是C 3 -C 4 - 烯基或Ar-CH（R'） - ，其中R'是氢或C 1 -C 4烷基， Ar是任选取代的C 6 -C 10 - 芳基，R 3是氢，C 3 -C 4 - 烯基，Ar-CH（R'） - ，其中R'是氢或C 1 -C 4烷基，Ar是任选取代的C 6 -C 10 - 芳基或COOR 4，其中R 4是C 1 -C 4 - 烷基或C 2 -C 4 - 烯基。 本发明还涉及一种制备这些化合物的方法及其使用方法。

公开(公告)号：US4336369A

公开(公告)日：1982-06-22

申请号：US149384

申请日：1980-05-13

申请人： Uwe Petersen ,  Eckart Voss ,  Peter Stadler

发明人： Uwe Petersen ,  Eckart Voss ,  Peter Stadler

IPC分类号： C07H15/236 ,  C07H15/22 ,  A61K31/71

CPC分类号： C07H15/236

摘要： The invention relates to selectively protected 1-N-(.omega.-aminoalkoxycarbonyl)-sisomicin derivatives and methods for their procurement. Said derivatives are useful as intermediates for the procurement of highly active antibacterial agents of low toxicity.

摘要翻译： 本发明涉及选择性保护的1-N-（ω-氨基烷氧基羰基） - 亚氨基蛋白衍生物及其采购方法。 所述衍生物可用作购买低活性的高活性抗菌剂的中间体。

公开(公告)号：US07378986B2

公开(公告)日：2008-05-27

申请号：US10526537

申请日：2003-08-22

申请人： Lutz Eckstein ,  Volker Entenmann ,  Markus Hess ,  Uwe Petersen ,  Werner Reichelt ,  Thomas Unselt ,  Cornelia Voigt ,  Richard Zimmer

发明人： Lutz Eckstein ,  Volker Entenmann ,  Markus Hess ,  Uwe Petersen ,  Werner Reichelt ,  Thomas Unselt ,  Cornelia Voigt ,  Richard Zimmer

IPC分类号： G08G1/00 ,  G08G1/16 ,  B60Q1/00

CPC分类号： G08G1/161 ,  G08G1/166

摘要： In a method and apparatus for radio-based issuing of warnings of hazards to the driver of a vehicle having a data receiver, the data receiver receives data from at least one data transmitter of at least one other vehicle, and evaluates the received data. The received data comprising information about the position, speed and direction of travel of the transmitting vehicle. The approach speed between the receiving vehicle and transmitting vehicle are determined in order to evaluate the received data in the receiving vehicle. According to the invention, in order to evaluate the received data in the receiving vehicle, the distance between the transmitting vehicle and the receiving vehicle is determined, and it is determined whether information is output to the driver, based on the distance between the transmitting vehicle and receiving vehicle, and based on the approach speed between the transmitting vehicle and receiving vehicle.

摘要翻译： 在用于向具有数据接收器的车辆的驾驶员发出危害警报的无线电发射的方法和装置中，数据接收器从至少一个其他车辆的至少一个数据发射机接收数据，并评估所接收的数据。 所接收的数据包括关于发送车辆的位置，速度和行进方向的信息。 确定接收车辆与发送车辆之间的接近速度，以评估接收车辆中的接收数据。 根据本发明，为了评估接收车辆中的接收数据，确定发送车辆与接收车辆之间的距离，并且基于发送车辆之间的距离来确定是否向驾驶员输出信息 以及接收车辆，并且基于发送车辆和接收车辆之间的接近速度。

公开(公告)号：US20060114123A1

公开(公告)日：2006-06-01

申请号：US10526537

申请日：2003-08-22

申请人： Lutz Eckstein ,  Volker Entenmann ,  Markus Hess ,  Uwe Petersen ,  Werner Reichelt ,  Thomas Unselt ,  Cornelia Voigt ,  Richard Zimmer

发明人： Lutz Eckstein ,  Volker Entenmann ,  Markus Hess ,  Uwe Petersen ,  Werner Reichelt ,  Thomas Unselt ,  Cornelia Voigt ,  Richard Zimmer

IPC分类号： G08G1/16 ,  G08B3/00

CPC分类号： G08G1/161 ,  G08G1/166

摘要： In a method and apparatus for radio-based issuing of warnings of hazards to the driver of a vehicle having a data receiver, the data receiver receives data from at least one data transmitter of at least one other vehicle, and evaluates the received data. The received data comprising information about the position, speed and direction of travel of the transmitting vehicle. The approach speed between the receiving vehicle and transmitting vehicle are determined in order to evaluate the received data in the receiving vehicle. According to the invention, in order to evaluate the received data in the receiving vehicle, the distance between the transmitting vehicle and the receiving vehicle is determined, and it is determined whether information is output to the driver, based on the distance between the transmitting vehicle and receiving vehicle, and based on the approach speed between the transmitting vehicle and receiving vehicle.

摘要翻译： 在用于向具有数据接收器的车辆的驾驶员发出危害警报的无线电发射的方法和装置中，数据接收器从至少一个其他车辆的至少一个数据发射机接收数据，并评估所接收的数据。 所接收的数据包括关于发送车辆的位置，速度和行进方向的信息。 确定接收车辆与发送车辆之间的接近速度，以评估接收车辆中的接收数据。 根据本发明，为了评估接收车辆中的接收数据，确定发送车辆与接收车辆之间的距离，并且基于发送车辆之间的距离来确定是否向驾驶员输出信息 以及接收车辆，并且基于发送车辆和接收车辆之间的接近速度。

公开(公告)号：US06432948B1

公开(公告)日：2002-08-13

申请号：US09436316

申请日：1999-11-08

申请人： Michael Matzke ,  Uwe Petersen ,  Thomas Jaetsch ,  Stephan Bartel ,  Thomas Schénke ,  Thomas Himmler ,  Bernd Baasner ,  Hans-Otto Werling ,  Klaus Schaller ,  Harald Labischinski

发明人： Michael Matzke ,  Uwe Petersen ,  Thomas Jaetsch ,  Stephan Bartel ,  Thomas Schénke ,  Thomas Himmler ,  Bernd Baasner ,  Hans-Otto Werling ,  Klaus Schaller ,  Harald Labischinski

IPC分类号： A61K315365

CPC分类号： C07D498/04 ,  A61K31/5383 ,  A61K31/5395 ,  C07D519/00

摘要： The invention relates to the use of quinolone- and naphthyridonecarboxylic acid derivatives, which are substituted in the 7-position by a 2-oxa-5,8-diazabicyclo[4.3.0]-non-8-yl) radical, and their pharmaceutically utilizable hydrates and/or salts for the therapy of Helicobacter pylori infections and the gastroduodenal disorders associated therewith.

摘要翻译： 本发明涉及使用2-氧杂-5,8-二氮杂双环[4.3.0] - 壬-8-基）基团在7-位取代的喹诺酮和萘啶酮羧酸衍生物及其药学上可接受的盐 用于治疗幽门螺杆菌感染的可利用的水合物和/或盐和与之相关的胃十二指肠疾病。

公开(公告)号：US3997533A

公开(公告)日：1976-12-14

申请号：US442810

申请日：1974-02-14

申请人： Hans-Joachim Kabbe ,  Uwe Petersen

发明人： Hans-Joachim Kabbe ,  Uwe Petersen

IPC分类号： A61K31/545 ,  B01J27/00 ,  C07B61/00 ,  C07D20060101 ,  C07D205/00 ,  C07D279/00 ,  C07D401/04 ,  C07D499/04 ,  C07D501/10 ,  C07D501/22 ,  C07D501/28 ,  C07D501/30 ,  C07D501/34

CPC分类号： C07D499/00

摘要： 7-Acylaminodesacetoxycephalosporanic acid derivatives are produced by heating a penicillin ester S-oxide to a temperature between 60.degree. C and 150.degree. C in the presence of a heavy metal salt.

摘要翻译： 通过在重金属盐的存在下将青霉素酯S-氧化物加热至60℃至150℃的温度来制备7-酰基乙酰氧基头孢烷酸衍生物。

公开(公告)号：US20060220908A1

公开(公告)日：2006-10-05

申请号：US10566834

申请日：2004-07-28

申请人： Uwe Petersen ,  Volker Schmid ,  Thomas Unselt

发明人： Uwe Petersen ,  Volker Schmid ,  Thomas Unselt

IPC分类号： G08G1/16

CPC分类号： B60T8/3275 ,  B60T7/22 ,  B60T2201/02 ,  B60T2201/03

摘要： The invention relates to a method and device for supporting the driver of a vehicle during an emergency braking process in order to prevent the vehicle from colliding with an object which is located in a detection zone in front of the vehicle in the direction of travel, in particular a preceding vehicle. In the method according to the invention braking means for braking the vehicle (50) are actuated independently of the driver if a predefined emergency braking condition is met and if it is determined that the driver wishes to carry out the emergency braking process, emergency braking information to the driver of the vehicle (50) being issued when the emergency braking condition is met. According to the invention information to the driver is issued even when the emergency braking condition is not met, said information informing the driver of the vehicle (50) about the current situation in the surroundings or the traffic situation in the detection zone (54), the information to the driver being adjusted as a function of predefined information conditions being met.

摘要翻译： 本发明涉及一种用于在紧急制动过程中支撑车辆驾驶员的方法和装置，以便防止车辆与位于车辆前方的检测区域中的物体沿行驶方向相撞， 特别是前一车辆。 在根据本发明的方法中，如果满足预定义的紧急制动条件，则独立于驾驶员致动用于制动车辆（50）的制动装置，并且如果确定驾驶员希望执行紧急制动过程，紧急制动信息 在满足紧急制动条件时向车辆（50）的驾驶员发出。 根据本发明，即使当不满足紧急制动条件时，也向驾驶员发出信息，所述信息通知车辆（50）的驾驶员关于周围环境中的当前情况或检测区（54）中的交通情况， 作为根据预定信息条件的函数调整驱动程序的信息。

公开(公告)号：US06308959B1

公开(公告)日：2001-10-30

申请号：US09254263

申请日：1999-03-01

申请人： Dirk Sokolihs ,  Uwe Petersen

发明人： Dirk Sokolihs ,  Uwe Petersen

IPC分类号： F16J1538

CPC分类号： F16J3/046 ,  Y10T403/315

摘要： An elastic sealing element in the form of bellows, which is used to seal the contact surface between at least two components movable in relation to one another is described, which has low-elasticity contact zones as well as a deformation zone whose elasticity is higher than that of the contact zones, wherein the said deformation zone defines a chamber for accommodating lubricants on its inner side facing the movable components. An overpressure relief means (14) is arranged at least in the area of one of the two low-elasticity contact zones (6 or 7). The overpressure relief means (14) has at least one relief opening (15) connecting the lubricant chamber (11) with the outside of the sealing element (1) and a closing element (16) covering the said relief opening. The closing element (16) is in turn made in one piece with the sealing element (1) and closes the relief opening (15) up to an overpressure limit in the lubricant chamber (11) due to the intrinsic elasticity of the material of the sealing element.

摘要翻译： 描述了波纹管形式的弹性密封元件，其用于密封可相对于彼此移动的至少两个部件之间的接触表面，其具有低弹性接触区域以及弹性高于 所述接触区域的所述变形区域限定用于在其面向所述可移动部件的内侧容纳润滑剂的腔室。 至少在两个低弹性接触区域（6或7）之一的区域中布置有超压释放装置（14）。 超压释放装置（14）具有将润滑剂室（11）与密封元件（1）的外部连接的至少一个释放开口（15）和覆盖所述浮雕开口的封闭元件（16）。 关闭元件（16）又与密封元件（1）一体制成，并且由于所述材料的固有弹性而将所述释放开口（15）封闭到所述润滑剂室（11）中的超压极限 密封元件。

公开(公告)号：US06271342B1

公开(公告)日：2001-08-07

申请号：US08930546

申请日：1997-09-25

申请人： Hans-Georg Lerchen ,  Karsten von dem Bruch ,  Uwe Petersen ,  Jörg Baumgarten ,  Norbert Piel ,  Horst-Peter Antonicek ,  Walter Weichel ,  Michael Sperzel ,  Klaus Dieter Bremm

发明人： Hans-Georg Lerchen ,  Karsten von dem Bruch ,  Uwe Petersen ,  Jörg Baumgarten ,  Norbert Piel ,  Horst-Peter Antonicek ,  Walter Weichel ,  Michael Sperzel ,  Klaus Dieter Bremm

IPC分类号： A61K3814

CPC分类号： C07D401/04 ,  A61K31/02 ,  C07D487/04 ,  C07H15/203 ,  C07K9/001 ,  Y02P20/55

摘要： The invention relates to cytostatics which, by modification with sugar, are tumor-specific. Suitable spacers ensure serum stability and at the same time an intracellular action.

摘要翻译： 本发明涉及通过用糖改性的肿瘤特异性的细胞抑制剂。 合适的间隔物确保血清稳定性，并同时进行细胞内作用。

公开(公告)号：US4294959A

公开(公告)日：1981-10-13

申请号：US74047

申请日：1979-09-10

申请人： Eckart Voss ,  Uwe Petersen ,  Peter Stadler

发明人： Eckart Voss ,  Uwe Petersen ,  Peter Stadler

IPC分类号： C07H15/236 ,  C07H23/00 ,  C07H17/00 ,  C07H15/22

CPC分类号： C07H23/00 ,  C07H15/236

摘要： The invention relates to selectively protected 4,6-di-O-(aminoglycosyl)-1,3-diamino cyclitols (and methods for their preparation) useful as intermediates for the synthesis of antibiotics, such as those of the sisomycin type.

摘要翻译： 本发明涉及可用作抗生素合成中间体的选择性保护的4,6-二-O-（氨基糖基）-1,3-二氨基环状醇（及其制备方法），该等抗生素如顺式霉素类型。