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130 条记录 (耗时 0.041 秒)

    Obesity treatment tools and methods
    91.
    发明申请
    Obesity treatment tools and methods 有权
    肥胖治疗工具和方法

    公开(公告)号：US20070118158A1

    公开(公告)日：2007-05-24

    申请号：US11654709

    申请日：2007-01-18

    申请人： Mark Deem ,  Douglas Sutton ,  Hanson Gifford ,  Bernard Andreas ,  Ronald French

    发明人： Mark Deem ,  Douglas Sutton ,  Hanson Gifford ,  Bernard Andreas ,  Ronald French

    IPC分类号： A61B17/08

    CPC分类号： A61B17/1114 ,  A61B17/00234 ,  A61B17/064 ,  A61B17/0644 ,  A61B17/122 ,  A61B2017/00557 ,  A61B2017/306 ,  A61B2090/395 ,  A61F5/0083 ,  A61F5/0086

    摘要： Various obesity treatment tools and methods are described herein, as well as treatments for other gastric-related diseases, e.g., GERD. Treatment includes reducing the size of the stomach pouch to limit the caloric intake as well as to provide an earlier feeling of satiety. This may be done by creating a smaller gastric pouch within the stomach directly from the interior of the stomach itself. The smaller pouches may be made through the use of individual anchoring devices, rotating probes, or volume reduction devices. A pyloroplasty procedure may also be performed to render the pyloric sphincter incompetent. A gastric bypass procedure may additionally be performed using atraumatic magnetic anastomoses devices so that sugars and fats are passed directly to the bowel while bypassing the stomach. Many of these procedures may be done in a variety of combinations. Treatment may create enforced behavioral modifications by discouraging the ingestion of high-caloric foods.

    摘要翻译： 本文描述了各种肥胖治疗工具和方法，以及用于其它胃相关疾病例如GERD的治疗。 治疗包括减小胃袋的尺寸以限制热量摄入以及提供较早的饱腹感。 这可以通过在胃内部直接从胃内部产生较小的胃袋来完成。 较小的袋可以通过使用单独的锚定装置，旋转探针或体积减小装置来制造。 还可以进行幽门成形术以使幽门括约肌无能力。 另外可以使用无创伤的磁性吻合装置进行胃旁路手术，使得糖和脂肪在绕过胃时直接通过肠。 这些程序中的许多可以以各种组合进行。 治疗可能会通过阻止摄入高热量食物而产生强制行为改变。

    Pericardium reinforcing devices and methods for using them
    93.
    发明申请
    Pericardium reinforcing devices and methods for using them 审中-公开
    心包加强装置及其使用方法

    公开(公告)号：US20070073100A1

    公开(公告)日：2007-03-29

    申请号：US11407883

    申请日：2006-04-19

    申请人： Ronald French ,  Sunmi Chew ,  Hanson Gifford ,  Bernard Andreas

    发明人： Ronald French ,  Sunmi Chew ,  Hanson Gifford ,  Bernard Andreas

    IPC分类号： A61F2/04

    CPC分类号： A61F2/2481

    摘要： A surgical device for reinforcing the pericardial sac surrounding the heart to assist in the treatment of congestive heart failure includes an enclosure having an interior and an exterior. The interior surface limits adhesions or accepts ingrowth with the myocardial tissue of the epicardium. The exterior surface is adapted to adhere to or otherwise attach to the pericardium to provide reinformcement.

    摘要翻译： 用于加强围绕心脏的心包囊以帮助治疗充血性心力衰竭的外科装置包括具有内部和外部的外壳。 内表面限制了与心外膜的心肌组织的粘连或接受向内生长。 外表面适于附着或以其他方式附着于心包以提供重塑。

    Methods and apparatus for treating hypertension
    95.
    发明申请
    Methods and apparatus for treating hypertension 有权
    治疗高血压的方法和装置

    公开(公告)号：US20060276852A1

    公开(公告)日：2006-12-07

    申请号：US11368577

    申请日：2006-03-06

    申请人： Denise Demarais ,  Hanson Gifford ,  Mark Deem ,  Douglas Sutton ,  Howard Levin ,  Mark Gelfand

    发明人： Denise Demarais ,  Hanson Gifford ,  Mark Deem ,  Douglas Sutton ,  Howard Levin ,  Mark Gelfand

    IPC分类号： A61N1/18

    CPC分类号： A61N1/05 ,  A61M5/14276 ,  A61M5/1723 ,  A61M2210/1082 ,  A61N1/0551 ,  A61N1/326 ,  A61N1/327 ,  A61N1/36017 ,  A61N1/36117 ,  A61N1/3627 ,  A61N1/40

    摘要： Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e., as compared to renal neuromodulation performed on neural tissue innervating a single kidney.

    摘要翻译： 提供了用于经由脉冲电场，经由刺激电场，经由局部药物递送，经由高频超声波，经由热技术等来治疗高血压的方法和装置。这种神经调节可以实现不可逆的电穿孔或电融合，坏死和 /或诱导凋亡，基因表达的改变，动作电位衰减或阻断，细胞因子上调的变化和靶神经纤维中的其他条件。 在一些实施方案中，神经调节被应用于有助于肾功能的神经纤维。 在一些实施方案中，这种神经调节以双向方式进行。 与单侧执行的肾神经调节相比，双侧肾神经调节可以在一些患者中提供增强的治疗效果，即与在支配单个肾脏的神经组织上进行的肾神经调节相比。

    Methods and apparatus for monopolar renal neuromodulation
    96.
    发明申请
    Methods and apparatus for monopolar renal neuromodulation 有权
    单极肾神经调节的方法和装置

    公开(公告)号：US20060265015A1

    公开(公告)日：2006-11-23

    申请号：US11403329

    申请日：2006-04-13

    申请人： Denise Demarais ,  Hanson Gifford ,  Mark Deem ,  Howard Levin ,  Mark Gelfand ,  US Zadno

    发明人： Denise Demarais ,  Hanson Gifford ,  Mark Deem ,  Howard Levin ,  Mark Gelfand ,  US Zadno

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36007 ,  A61N1/0551 ,  A61N1/32 ,  A61N1/327

    摘要： Methods and apparatus are provided for monopolar neuromodulation, e.g., via a pulsed electric field. Such monopolar neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, monopolar neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such monopolar neuromodulation is performed bilaterally.

    摘要翻译： 提供了用于单极神经调节的方法和装置，例如通过脉冲电场。 这种单极神经调节可能会导致不可逆的电穿孔或电融合，坏死和/或诱导凋亡，基因表达的改变，动作电位减弱或阻断，细胞因子上调的变化和靶神经纤维中的其他条件。 在一些实施方案中，单极神经调节被应用于有助于肾功能的神经纤维。 在一些实施方案中，这种单极神经调节是双侧进行的。

    Methods and apparatus for treating end-stage renal disease
    98.
    发明申请
    Methods and apparatus for treating end-stage renal disease 有权
    治疗终末期肾病的方法和装置

    公开(公告)号：US20060212076A1

    公开(公告)日：2006-09-21

    申请号：US11368949

    申请日：2006-03-06

    申请人： Denise Demarais ,  Hanson Gifford ,  Mark Deem ,  Douglas Sutton ,  Howard Levin ,  Mark Gelfand

    发明人： Denise Demarais ,  Hanson Gifford ,  Mark Deem ,  Douglas Sutton ,  Howard Levin ,  Mark Gelfand

    IPC分类号： A61N1/18

    CPC分类号： A61N1/05 ,  A61N1/0551 ,  A61N1/327 ,  A61N1/40

    摘要： Methods and apparatus are provided for treating end-stage renal disease, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e., as compared to renal neuromodulation performed on neural tissue innervating a single kidney.

    摘要翻译： 提供了用于通过脉冲电场经由刺激电场，经由局部药物递送，经由高频超声波，经由热技术等来治疗终末期肾脏疾病的方法和装置。这种神经调节可以实现不可逆的电穿孔或 电融合，坏死和/或诱导凋亡，基因表达改变，动作电位减弱或阻断，细胞因子上调和靶神经纤维中的其他条件的变化。 在一些实施方案中，神经调节被应用于有助于肾功能的神经纤维。 在一些实施方案中，这种神经调节以双向方式进行。 与单侧执行的肾神经调节相比，双侧肾神经调节可以在一些患者中提供增强的治疗效果，即与在支配单个肾脏的神经组织上进行的肾神经调节相比。

    System and methods for performing endovascular procedures
    100.
    发明申请
    System and methods for performing endovascular procedures 审中-公开

    公开(公告)号：US20060058775A1

    公开(公告)日：2006-03-16

    申请号：US11120335

    申请日：2005-05-03

    申请人： John Stevens ,  William Peters ,  Wesley Sterman ,  Hanson Gifford

    发明人： John Stevens ,  William Peters ,  Wesley Sterman ,  Hanson Gifford

    IPC分类号： A61M31/00

    CPC分类号： A61B17/3421 ,  A61B17/320783 ,  A61B2017/00243 ,  A61B2017/22067 ,  A61B2090/3784 ,  A61F2/958 ,  A61M25/0032 ,  A61M25/10 ,  A61M2025/0681 ,  A61M2025/1052

    摘要： A system for inducing cardioplegic arrest and performing an endovascular procedure within the heart or blood vessels of a patient. An endoaortic partitioning catheter has an inflatable balloon which occludes the ascending aorta when inflated. Cardioplegic fluid may be infused through a lumen of the endoaortic partitioning catheter to stop the heart while the patient's circulatory system is supported on cardiopulmonary bypass. One or more endovascular devices are introduced through an internal lumen of the endoaortic partitioning catheter to perform a diagnostic or therapeutic endovascular procedure within the heart or blood vessels of the patient. Surgical procedures such as coronary artery bypass surgery or heart valve replacement may be performed in conjunction with the endovascular procedure while the heart is stopped. Embodiments of the system are described for performing: fiberoptic angioscopy of structures within the heart and its blood vessels, valvuloplasty for correction of valvular stenosis in the aortic or mitral valve of the heart, angioplasty for therapeutic dilatation of coronary artery stenoses, coronary stenting for dilatation and stenting of coronary artery stenoses, atherectomy or endarterectomy for removal of atheromatous material from within coronary artery stenoses, intravascular ultrasonic imaging for observation of structures and diagnosis of disease conditions within the heart and its associated blood vessels, fiberoptic laser angioplasty for removal of atheromatous material from within coronary artery stenoses, transmyocardial revascularization using a side-firing fiberoptic laser catheter from within the chambers of the heart, and electrophysiological mapping and ablation for diagnosing and treating electrophysiological conditions of the heart.