公开(公告)号：US6013773A

公开(公告)日：2000-01-11

申请号：US791728

申请日：1997-01-31

申请人： Hideki Kobayashi ,  Mihoko Aoki ,  Hiroshi Uchida ,  Nobumi Kusuhara ,  Yukio Miyama ,  Teruo Ito ,  Akira Fukuhara ,  Tsutomu Sato

发明人： Hideki Kobayashi ,  Mihoko Aoki ,  Hiroshi Uchida ,  Nobumi Kusuhara ,  Yukio Miyama ,  Teruo Ito ,  Akira Fukuhara ,  Tsutomu Sato

IPC分类号： A61K38/27 ,  A61K47/18 ,  A61K47/22 ,  A61K47/26 ,  A61K38/00

CPC分类号： A61K38/27 ,  A61K47/183 ,  A61K47/22 ,  A61K47/26 ,  A61K9/0019

摘要： A stable pharmaceutical preparation containing a human growth hormone having a molecular weight of about 20,000, or a derivative thereof, can be formulated by adding a water soluble heterocyclic compound, such as creatinine, a salt of acetyltryptophane and nicotinamide, to prevent the insolubilization of the human growth hormone or the derivative thereof in an aqueous solution.

摘要翻译： 含有分子量约为20,000的人生长激素或其衍生物的稳定药物制剂可通过加入水溶性杂环化合物如肌酸酐，乙酰色氨酸和烟酰胺的盐来配制，以防止不溶性 人生长激素或其衍生物在水溶液中。

公开(公告)号：US5880294A

公开(公告)日：1999-03-09

申请号：US981814

申请日：1998-01-06

申请人： Makoto Nomura ,  Hideki Kazuno ,  Tsutomu Sato ,  Masato Washinosu ,  Motoaki Tanaka ,  Akira Matsuda ,  Tetsuji Asao

发明人： Makoto Nomura ,  Hideki Kazuno ,  Tsutomu Sato ,  Masato Washinosu ,  Motoaki Tanaka ,  Akira Matsuda ,  Tetsuji Asao

IPC分类号： C07H9/04 ,  C07H13/04 ,  C07H19/04 ,  C07D307/12 ,  C07D307/20 ,  C07D317/44

CPC分类号： C07H9/04 ,  C07H13/04 ,  C07H19/04

摘要： The present invention relates to D-pentofuranose derivatives represented by the following formulas (1) through (4): ##STR1## (wherein A represents a chlorobenzoyl group; R.sup.1 represents a hydrogen atom, an aliphatic lower acyl group, a substituted or unsubstituted benzoyl group; each of X and Y represents a lower alkyl group; Z represents an ethynyl group or tri-lower alkyl silylethynyl group; the sugar moiety in formula (1) represents xylose; and the sugar moiety of each of formulas (3) and (4) represents ribose). The present invention also relates to a process for preparing the compound (2) characterized by oxidizing the compound of formula (1) with a hypochlorite in the presence of a catalytic amount of 2,2,6,6-tetramethylpiperidinoxy compound, and these compounds are useful as intermediates in the synthesis of 3'-C-substituted ribonucleoside derivatives having excellent antitumor activities.

摘要翻译： PCT No.PCT / JP97 / 01427 Sec。 371日期：1998年1月6日 102（e）日期1998年1月6日PCT 1997年4月24日PCT公布。 公开号WO97 / 43295 日期：1997年11月20日本发明涉及由下式（1）〜（4）表示的D-呋喃糖衍生物：＆lt; IMAGE＆gt;（2）＆lt; IMAGE＆gt;（3） ）（其中A表示氯苯甲酰基; R1表示氢原子，脂肪族低级酰基，取代或未取代的苯甲酰基; X和Y各自表示低级烷基; Z表示乙炔基或三低级烷基甲硅烷基乙炔基 式（1）中的糖部分表示木糖;式（3）和（4）各自的糖部分表示核糖）。 本发明还涉及一种制备化合物（2）的方法，其特征在于在催化量的2,2,6,6-四甲基哌啶氧基化合物存在下，用次氯酸盐氧化式（1）化合物，这些化合物 可用作合成具有优异抗肿瘤活性的3'-取代核糖核苷衍生物的中间体。

公开(公告)号：US5871149A

公开(公告)日：1999-02-16

申请号：US977323

申请日：1997-11-24

申请人： Takahiro Moroi ,  Takashi Ban ,  Fumihiko Kitani ,  Tsutomu Sato

发明人： Takahiro Moroi ,  Takashi Ban ,  Fumihiko Kitani ,  Tsutomu Sato

IPC分类号： B60H1/08 ,  F24J3/00 ,  B60H1/02

CPC分类号： F24J3/003

摘要： A viscous fluid type heat generator including a housing assembly defining a heat generating chamber, a fluid storing chamber communicated through fluid passageway means with the heat generating chamber, and a heat receiving chamber for permitting a heat exchanging fluid to circulate therethrough to receive heat from the heat generating chamber. A rotor element is mounted on a drive shaft for rotation in the heat generating chamber with a gap defined between the inner wall surfaces of the heat generating chamber and the outer faces of the rotor element. The fluid passageway means includes a fluid withdrawing passageway for withdrawing the viscous fluid from the gap into the fluid storing chamber and a fluid supply passageway for supplying the viscous fluid from the fluid storing chamber into the gap. The fluid withdrawing passageway has a separate duct configuration and opens at one end to an outer peripheral region of the heat generating chamber to communicate the outer peripheral region with the fluid storing chamber. The fluid supply passageway has a separate duct configuration and opens at one end to a radially inner region of the heat generating chamber to communicate the radially inner region with the fluid storing chamber.

摘要翻译： 一种粘性流体型热发生器，其包括限定发热室的壳体组件，通过流体通道装置与发热室连通的流体存储腔，以及用于允许热交换流体从其中循环通过的热接收室， 发热室。 转子元件安装在驱动轴上，用于在发热室中旋转，并且在发热室的内壁表面和转子元件的外表面之间具有间隙。 流体通道装置包括用于将粘性流体从间隙抽出到流体存储室中的流体抽出通道和用于将粘性流体从流体存储室供给到间隙中的流体供应通道。 流体抽出通道具有单独的管道构造，并且在一端开放到发热室的外周区域，以将外围区域与流体存储室连通。 流体供应通道具有单独的管道构造，并且在一端开放到发热室的径向内部区域，以将径向内部区域与流体存储室连通。

公开(公告)号：US5842100A

公开(公告)日：1998-11-24

申请号：US906263

申请日：1997-08-05

申请人： Tsukasa Yanashima ,  Masatoshi Takano ,  Tomoyuki Nishikawa ,  Tsutomu Sato ,  Kasumi Yamamoto ,  Yutaka Ishikawa

发明人： Tsukasa Yanashima ,  Masatoshi Takano ,  Tomoyuki Nishikawa ,  Tsutomu Sato ,  Kasumi Yamamoto ,  Yutaka Ishikawa

IPC分类号： B65H5/06 ,  G03G15/20

CPC分类号： G03G15/2035 ,  G03G15/2032 ,  G03G2215/00459

摘要： A fixing unit includes a heat roller accommodating a heater and a press roller movable toward and away from the heat roller. Both shaft members of the heat roller are supported by two receiving members, with a clearance provided between each shaft member and respective receiving member. A driven gear is provided to one of the shaft member, which engages a rotating mechanism for rotating the heat roller. The fixing unit further includes a biasing member which biases the other shaft of the heat roller away from the press roller within the clearance, in such a manner that the heat roller and the press roller become parallel when the above-described one shaft member is urged away from the press roller due to the meshing engagement of the driven gear and the rotating mechanism.

摘要翻译： 定影单元包括容纳加热器的加热辊和可朝向和远离加热辊移动的加压辊。 加热辊的两个轴构件由两个接收构件支撑，每个轴构件和相应的接收构件之间具有间隙。 从动齿轮设置在轴构件中的一个上，该轴构件接合用于旋转加热辊的旋转机构。 定影单元还包括偏置构件，该偏置构件使加热辊的另一个轴偏离压辊在间隙内，使得当上述一个轴构件被推动时加热辊和压辊变平行 由于从动齿轮和旋转机构的啮合而远离压辊。

公开(公告)号：US5828479A

公开(公告)日：1998-10-27

申请号：US929003

申请日：1997-09-04

申请人： Masatoshi Takano ,  Eiji Takasugi ,  Shinji Kikuchi ,  Tsutomu Sato ,  Hiroyuki Saito ,  Yoshiyuki Araki ,  Mitsunori Iima ,  Takashi Sasaki ,  Takashi Iizuka

发明人： Masatoshi Takano ,  Eiji Takasugi ,  Shinji Kikuchi ,  Tsutomu Sato ,  Hiroyuki Saito ,  Yoshiyuki Araki ,  Mitsunori Iima ,  Takashi Sasaki ,  Takashi Iizuka

IPC分类号： G02B26/10 ,  G02B13/00 ,  G02B13/18 ,  G02B26/12 ,  H04N1/113 ,  G02B26/08

CPC分类号： B41J2/473 ,  G02B26/12 ,  H04N1/1135

摘要： A cascade scanning optical system which includes: a pair of laser scanning optical systems each having a laser beam emitter and a laser beam deflector, wherein a laser beam emitted by the laser beam emitter enters the laser beam deflector so that the laser beam deflector deflects the laser beam to scan a surface of a member such that the laser beams proceed to the surface on a common line thereon in respective ranges of the common line; a pair of mirrors respectively provided in the pair of laser scanning optical systems, each of the pair of mirrors being positioned in a corresponding optical path between the laser beam deflector and the member to reflect a laser beam incident thereon toward the surface; a pair of cylindrical lenses having power in a sub-scanning direction, respectively provided in the pair of laser scanning optical systems, each of the pair of cylindrical lenses being positioned in a corresponding optical path between the laser beam emitter and the laser beam deflector; first means for adjusting an angle of at least one of the pair of mirrors relative to the surface; and second means for adjusting a position of at least one of the pair of cylindrical lenses relative to a corresponding one of the laser beam deflectors.

摘要翻译： 一种级联扫描光学系统，其包括：一对激光扫描光学系统，每个具有激光束发射器和激光束偏转器，其中由激光束发射器发射的激光束进入激光束偏转器，使得激光束偏转器偏转 激光束扫描构件的表面，使得激光束在公共线的相应范围内前进到其上的公共线上的表面; 分别设置在一对激光扫描光学系统中的一对反射镜，每对反射镜位于激光束偏转器和构件之间的相应光路中，以反射入射到其上的激光束; 分别设置在该对激光扫描光学系统中的副副扫描方向上具有动力的一对柱面透镜，所述一对柱面透镜中的每一个位于激光束发射器和激光束偏转器之间的相应光路中; 用于调整所述一对反射镜中的至少一个相对于所述表面的角度的第一装置; 以及用于相对于相应的一个激光束偏转器来调节所述一对柱面透镜中的至少一个的位置的第二装置。

公开(公告)号：US5691277A

公开(公告)日：1997-11-25

申请号：US501842

申请日：1995-07-13

申请人： Hisashi Kanno ,  Youichi Kanda ,  Susumu Shimizu ,  Yoshikazu Kubota ,  Tsutomu Sato ,  Masato Arahira

发明人： Hisashi Kanno ,  Youichi Kanda ,  Susumu Shimizu ,  Yoshikazu Kubota ,  Tsutomu Sato ,  Masato Arahira

IPC分类号： A01N43/40 ,  C07D213/69 ,  C07D213/84

CPC分类号： C07D213/69 ,  A01N43/40 ,  C07D213/84

摘要： A 2-(unsubstituted or substituted) (benzyloxy or phenoxy)-4-substituted-6-(meta-substituted phenoxy)pyridine represented by the formula (I): ##STR1## wherein R represents C.sub.1 -C.sub.4 alkoxy or cyano; each X, which may be identical or different if n is greater than 1, represents a halogen, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkythio, C.sub.3 -C.sub.5 alkenyloxy, or C.sub.3 -C.sub.5 alkynyloxy; Y represents trifluoromethyl, difluoromethoxy, trifluoromethoxy, or trifluoromethylthio; m represents an integer of 0 or 1; and n represents an integer of 0 to 5, which is useful as a herbicide.

摘要翻译： 由式（I）表示的2-（未取代或取代的）（苄氧基或苯氧基）-4-取代-6-（间位取代的苯氧基）吡啶：其中R表示C1-C4烷氧基或氰基 ; 如果n大于1，每个X可以相同或不同，表示卤素，C1-C4烷氧基，C1-C4烷基，C1-C4卤代烷氧基，C1-C4卤代烷基，C1-C4卤代链环，C3-C5链烯氧基， 或C 3 -C 5炔氧基; Y表示三氟甲基，二氟甲氧基，三氟甲氧基或三氟甲硫基; m表示0或1的整数; n表示0〜5的整数，作为除草剂有用。

公开(公告)号：US5658888A

公开(公告)日：1997-08-19

申请号：US318814

申请日：1994-10-19

申请人： Hiroshi Koga ,  Tsutomu Sato ,  Hisanori Takanashi

发明人： Hiroshi Koga ,  Tsutomu Sato ,  Hisanori Takanashi

IPC分类号： C07D407/00 ,  C07H17/08 ,  A61K31/00 ,  A61K31/70 ,  A61K31/7042 ,  A61K31/7048 ,  A61P1/00 ,  A61P1/12 ,  A61P43/00 ,  C07M17/08

CPC分类号： C07H17/08

摘要： Compounds represented by the general formula: ##STR1## wherein R.sub.1 is a hydrogen atom or an acyl group; R.sub.2 and R.sub.3 may be the same or different, and each represents a hydrogen atom, hydroxyl group, acyloxy group or amino group, or, in combination, they represent .dbd.O or .dbd.NOR.sub.10, where R.sub.10 represents a hydrogen atom or lower alkyl group;R.sub.4 represents a hydrogen atom or lower alkyl group; andY represents --NR.sub.5 R.sub.6 or --N.sup.+ R.sub.7 R.sub.8 R.sub.9 X.sup.-, where R.sub.5, R.sub.6, R.sub.7, R.sub.8 and R.sub.9 may be the same or different, and each represents a hydrogen atom or an unsubstituted or substituted lower alkyl group, lower alkenyl group, lower alkinyl group, cycloalkyl group or 3-7-membered heterocyclic group comprising an oxygen atom, nitrogen atom or sulphur atom as an heteroatom, and X represents an anion, where R.sub.5 and R.sub.6, or R.sub.7 and R.sub.8 may form an azacycloalkyl group together with the neighboring nitrogen atom, respectively, and salts thereof.These compounds and their salts are subject to a remarkably lower degree of decomposition by gastric acid than are the publicly known erythromycin derivatives of the prior art, and have an excellent enterolinesis stimulating action.

摘要翻译： PCT No.PCT / JP93 / 00702 Sec。 371日期：1994年10月19日 102（e）日期1994年10月19日PCT提交1993年5月26日PCT公布。 出版物WO93 / 24509 日期1993年12月9日化合物由通式表示的化合物：酰基; R2和R3可以相同或不同，各自表示氢原子，羟基，酰氧基或氨基，或者组合表示= O或= NOR10，其中R10表示氢原子或低级烷基; R4代表氢原子或低级烷基; 并且Y表示-NR5R6或-N + R7R8R9X-，其中R5，R6，R7，R8和R9可以相同或不同，并且各自表示氢原子或未取代或取代的低级烷基，低级烯基，低级炔基 基团，环烷基或包含氧原子，氮原子或硫原子作为杂原子的3-7元杂环基，X表示阴离子，其中R 5和R 6或R 7和R 8可以与相邻的基团一起形成氮杂环烷基 氮原子及其盐。 与现有技术中公知的红霉素衍生物相比，这些化合物及其盐受胃酸分解程度明显降低，具有优异的肠溶激素作用。

公开(公告)号：US5624942A

公开(公告)日：1997-04-29

申请号：US503903

申请日：1995-07-18

申请人： Hisashi Kanno ,  Youichi Kanda ,  Susumu Shimizu ,  Yoshikazu Kubota ,  Tsutomu Sato ,  Masato Arahira

发明人： Hisashi Kanno ,  Youichi Kanda ,  Susumu Shimizu ,  Yoshikazu Kubota ,  Tsutomu Sato ,  Masato Arahira

IPC分类号： C07D409/12 ,  C07D405/12 ,  A61K31/44

CPC分类号： C07D409/12

摘要： A 2-phenoxy-6-thienylmethyloxypyridine derivative represented by the formula (I): ##STR1## wherein R represents hydrogen, a halogen, cyano, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 alkylamino, or di (C.sub.1 -C.sub.4 alkyl) amino;each X, which may be identical or different if n is greater than 1, represents a halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, or C.sub.1 -C.sub.4 haloalkyl;each Y, which may be identical or different if m is greater than 1, represents a halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkoxy, or C.sub.1 -C.sub.4 haloalkylthio;m represents an integer of 0 to 5; andn represents an integer of 0 to 3, which is useful as a herbicide.

摘要翻译： 由式（I）表示的2-苯氧基-6-噻吩基甲基氧基吡啶衍生物：其中R表示氢，卤素，氰基，C1-C4烷基，C1-C4烷氧基，C1-C4烷硫基，C1- C4卤代烷基，C1-C4烷基氨基或二（C1-C4烷基）氨基; 如果n大于1，每个X可以相同或不同，表示卤素，C 1 -C 4烷基，C 1 -C 4烷氧基，C 1 -C 4烷硫基或C 1 -C 4卤代烷基; 如果m大于1，每个Y可以相同或不同，表示卤素，C 1 -C 4烷基，C 1 -C 4烷氧基，C 1 -C 4烷硫基，C 1 -C 4卤代烷基，C 1 -C 4卤代烷氧基或C 1 -C 4卤代烷硫基 ; m表示0〜5的整数， n表示0〜3的整数，作为除草剂有用。

公开(公告)号：US5475872A

公开(公告)日：1995-12-12

申请号：US175520

申请日：1993-12-30

申请人： Tsutomu Sato

发明人： Tsutomu Sato

IPC分类号： H04B1/38 ,  H04M1/02 ,  H04M1/60 ,  H04W88/02 ,  H04M11/02

CPC分类号： H04M1/6058 ,  H04B1/3833

摘要： A transmitter-receiver comprises a transmitter, a transmitter circuit, a receiver circuit, a receiver, a jack, and a switch. The transmitter circuit converts a first audio signal to a transmit signal and transmits the transmit signal. The receiver circuit extracts a second audio signal from a received signal. The jack is adapted to be connected with a plug of an external transmitter-receiver. The switch is on/off controlled dependent on whether or not the jack of the external transmitter-receiver is connected with the plug. The switch, when the jack is not connected with the plug, supplies the first audio signal from the transmitter to the transmitter circuit and also supplies the second audio signal from the receiver circuit selectively to the receiver. Further, the switch, when the jack is connected with the plug, supplies an input signal from the external transmitter-receiver to the transmitter circuit through the connected plug and jack and also supplies the second audio signal from the receiver circuit selectively to the external transmitter-receiver through the connected jack and plug.

摘要翻译： 发射机 - 接收机包括发射机，发射机电路，接收机电路，接收机，插座和交换机。 发射机电路将第一音频信号转换为发射信号并发射发射信号。 接收机电路从接收信号中提取第二音频信号。 插座适于与外部发射器 - 接收器的插头连接。 开关根据外部发射器 - 接收器的插孔是否与插头连接而进行开/关控制。 当插座未与插头连接时，该开关将来自发射机的第一音频信号提供给发射机电路，并且还将来自接收机电路的第二音频信号选择性地提供给接收机。 此外，当插座与插头连接时，开关通过所连接的插头和插座将来自外部发射器 - 接收器的输入信号提供给发射器电路，并且还将来自接收器电路的第二音频信号有选择地提供给外部发射器 - 通过连接的插孔和插头接收。

公开(公告)号：US5305068A

公开(公告)日：1994-04-19

申请号：US872834

申请日：1992-04-23

申请人： Tsutomu Sato ,  Masatoshi Takano ,  Taizo Saito ,  Hiroyuki Yamaguchi

发明人： Tsutomu Sato ,  Masatoshi Takano ,  Taizo Saito ,  Hiroyuki Yamaguchi

IPC分类号： B41J11/30 ,  B41J15/04 ,  B65H20/20 ,  G03G21/00 ,  G03G15/00

CPC分类号： B41J15/04 ,  B41J11/30 ,  B65H20/20

摘要： A printer, for printing on continuous recording paper, includes tractors disposed in the recording paper feed path of the printer, with each of the tractors circumferentially travelling in synchronism with movement of the continuous recording paper when the tractors engage feed holes of the continuous paper. When no printing operation is performed, travel of the tractors can be prevented by operation of an electromagnetic clutch, or a combination of one way clutches. Further, the printer uses an electrophotographic method wherein when no printing operation is performed, a transfer charger or fixing roller can be retracted from an operational position. A lever, associated with movement of the transfer charge or fixing roller, is pressed against and locked with the pulley fixed to the rotating shaft of each of the tractors to thereby prohibit the movement of the tractor. Further, a swingable arm can be provided having an engaging projection capable of being locked with the feed holes of the continuous recording paper. The swingable arm is swung in association with the movement of the transfer charger or fixing roller, which can be retracted from the operational position when no printing operation is performed. Thus, the engaging projection is engaged with the feed hole of the continuous recording paper to thereby regulate the movement of the continuous recording paper.

摘要翻译： 用于在连续记录纸上打印的打印机包括设置在打印机的记录纸馈送路径中的拖拉机，当拖拉机与连续纸张的进给孔接合时，每个拖拉机与连续记录纸的移动同步地沿周向行进。 当不执行打印操作时，可以通过操作电磁离合器或单向离合器的组合来防止拖拉机的行驶。 此外，打印机使用电子照相方法，其中当不执行打印操作时，转印充电器或定影辊可以从操作位置缩回。 与传送装料或定影辊的移动相关联的杆被固定在每个拖拉机的旋转轴上的滑轮压紧并锁定，从而禁止拖拉机的移动。 此外，可以提供具有能够与连续记录纸的进给孔锁定的接合突起的可摆动臂。 可转动臂与转印充电器或定影辊的移动相关联地摆动，当不进行打印操作时，可以从操作位置缩回。 因此，接合突起与连续记录纸的进给孔接合，从而调节连续记录纸的移动。