公开(公告)号：US09696267B2

公开(公告)日：2017-07-04

申请号：US15216655

申请日：2016-07-21

Applicant: Okinawa Institute of Science and Technology School Corporation

Inventor： Faisal Mahmood ,  Lars-Göran Wallentin Öfverstedt ,  Bo Ulf Skoglund

IPC: G06K9/00 ,  G01N23/04 ,  G06T11/00

Abstract: Apparatus for improving a three-dimensional (3D) reconstruction of a sample is programmed to execute instructions including: removing uncorrelated noise in said 3D reconstruction with COMET or other regularization techniques; and removing correlated noise in said 3D reconstruction by applying an Extended Field Iterative Reconstruction Technique (EFIRT) procedure.

公开(公告)号：US09633842B2

公开(公告)日：2017-04-25

申请号：US14774226

申请日：2014-03-07

Applicant: Okinawa Institute of Science and Technology School Corporation

Inventor： Vidya Dhar Singh ,  Cathal Cassidy ,  Mukhles Ibrahim Sowwan

IPC: H01L21/02 ,  C30B1/02 ,  C30B28/02 ,  C30B29/06 ,  C30B29/60 ,  H01L29/04 ,  H01L29/16 ,  C01B33/021

CPC classification number: H01L21/02658 ,  C01B33/021 ,  C30B1/023 ,  C30B28/02 ,  C30B29/06 ,  C30B29/60 ,  H01L21/02532 ,  H01L21/02601 ,  H01L21/02631 ,  H01L29/04 ,  H01L29/16

Abstract: A method of forming crystallized semiconductor particles includes: forming amorphous semiconductor particles in a vacuumed aggregation chamber; transporting the amorphous semiconductor particles formed in the vacuumed aggregation chamber to a vacuumed deposition chamber within which a substrate is held; and applying a vapor of a metal catalyst to the amorphous semi-conductor particles while still in transit to the substrate in the vacuumed deposition chamber to induce crystallization of at least portion of the amorphous semiconductor particles via the metal catalyst in the transit, thereby depositing the crystallized semiconductor particles with the metal catalyst attached thereto onto the substrate.

公开(公告)号：US20160356728A1

公开(公告)日：2016-12-08

申请号：US15216655

申请日：2016-07-21

Applicant: Okinawa Institute of Science and Technology School Corporation

Inventor： Faisal MAHMOOD ,  Lars-Göran Wallentin ÖFVERSTEDT ,  Bo Ulf SKOGLUND

IPC: G01N23/04

CPC classification number: G01N23/046 ,  G01N2223/401 ,  G01N2223/419 ,  G01N2223/42 ,  G01N2223/612 ,  G06T11/006 ,  G06T2211/432

Abstract: Apparatus for improving a three-dimensional (3D) reconstruction of a sample is programmed to execute instructions including: removing uncorrelated noise in said 3D reconstruction with COMET or other regularization techniques; and removing correlated noise in said 3D reconstruction by applying an Extended Field Iterative Reconstruction Technique (EFIRT) procedure.

Abstract translation: 用于改进样本的三维（3D）重建的装置被编程以执行指令，包括：使用COMET或其他正则化技术去除所述3D重建中的不相关噪声; 以及通过应用扩展场迭代重构技术（EFIRT）来去除所述3D重构中的相关噪声。

公开(公告)号：US20160251328A1

公开(公告)日：2016-09-01

申请号：US15148716

申请日：2016-05-06

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION

Inventor： Pandurang V. CHOUTHAIWALE ,  Fujie TANAKA

IPC: C07D309/28

CPC classification number: C07D309/28 ,  C07C201/14 ,  C07C205/55 ,  C07C2601/14 ,  C07D241/44 ,  C07D243/02 ,  C07D307/54 ,  C07D309/30 ,  C07D317/30 ,  C07D407/04

Abstract: Disclosed is a process for preparing dihydro-2H-pyran derivatives of formula I: wherein R1 and R2 are defined herein. The process of the invention provides the compound of formula I in concise cascade reactions and in one pot. The compound of formulae I prepared by the process of the invention and its further transformed derivatives are useful for making pharmaceutical composition for the treatment of proliferative diseases.

公开(公告)号：US09309261B2

公开(公告)日：2016-04-12

申请号：US14431935

申请日：2013-10-04

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION

Inventor： Hai-Lei Cui ,  Fujie Tanaka

IPC: C07D491/107 ,  A61K31/407

CPC classification number: C07D491/107

Abstract: Disclosed is a compound of formula I: wherein R1?, R2?, R3?, R4?, R5?, n and m are defined herein. The compound of formula I is prepared by a concise, catalytic enantioselective formal hetero-Diels-Alder (hDA) reactions of enones with isatins and is useful for making pharmaceutical composition for the treatment of proliferative diseases.

Abstract translation: 公开了式I的化合物：其中R 1，R 2，R 3，R 4，R 5，n和m如本文所定义。 式I的化合物通过烯酮与异硬脂酸酯的简明的催化对映选择性形式的异二聚体 - 狄尔斯（hDA）反应制备，并且可用于制备用于治疗增殖性疾病的药物组合物。

公开(公告)号：US20160042948A1

公开(公告)日：2016-02-11

申请号：US14774226

申请日：2014-03-07

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION

Inventor： Singh VIDYA DHAR ,  Cathal CASSIDY ,  Mukhles Ibrahim SOWWAN

IPC: H01L21/02 ,  H01L29/04 ,  H01L29/16

CPC classification number: H01L21/02658 ,  C01B33/021 ,  C30B1/023 ,  C30B28/02 ,  C30B29/06 ,  C30B29/60 ,  H01L21/02532 ,  H01L21/02601 ,  H01L21/02631 ,  H01L29/04 ,  H01L29/16

Abstract: A method of forming crystallized semiconductor particles includes: forming amorphous semiconductor particles in a vacuumed aggregation chamber; transporting the amorphous semiconductor particles formed in the vacuumed aggregation chamber to a vacuumed deposition chamber within which a substrate is held; and applying a vapor of a metal catalyst to the amorphous semi-conductor particles while still in transit to the substrate in the vacuumed deposition chamber to induce crystallization of at least portion of the amorphous semiconductor particles via the metal catalyst in the transit, thereby depositing the crystallized semiconductor particles with the metal catalyst attached thereto onto the substrate.

Abstract translation: 形成结晶化半导体颗粒的方法包括：在真空聚集室中形成非晶半导体颗粒; 将形成在真空聚集室中的非晶半导体颗粒输送到其中保持基板的真空沉积室; 以及将金属催化剂的蒸气施加到所述非晶半导体颗粒上，同时仍然在所述真空沉积室中转移到所述基板上，以在所述运输过程中经由所述金属催化剂引起至少部分所述非晶半导体颗粒的结晶，由此沉积 将结合了金属催化剂的半导体颗粒结合到基板上。

公开(公告)号：US20160003752A1

公开(公告)日：2016-01-07

申请号：US14770245

申请日：2014-03-05

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION

Inventor： Faisal MAHMOOD ,  Lars-Göran Wallentin ÖFVERSTEDT ,  Bo Ulf SKOGLUND

IPC: G01N23/04

CPC classification number: G01N23/046 ,  G01N2223/401 ,  G01N2223/419 ,  G01N2223/42 ,  G01N2223/612 ,  G06T11/006 ,  G06T2211/432

Abstract: Computerized method and system for improving 3D reconstruction images involves applying the Extended Field Iterative Reconstruction Technique (EFIRT) to remove correlated noise, in addition to using COMET (constrained maximum relative entropy tomography) to eliminate uncorrelated noise, wherein the EFIRT is applied by performing a set of successive reconstructions on an extended field larger than a region of interest (ROI); and extracting and averaging the ROI from said set of successive reconstructions.

Abstract translation: 用于改进3D重建图像的计算机化方法和系统包括应用扩展场迭代重建技术（EFIRT）来消除相关噪声，以及使用COMET（约束最大相对熵断层扫描）来消除不相关噪声，其中EFIRT通过执行 在大于感兴趣区域（ROI）的扩展场上的连续重建集合; 以及从所述连续重建集合中提取和平均所述ROI。

公开(公告)号：US20150246896A1

公开(公告)日：2015-09-03

申请号：US14431945

申请日：2013-10-10

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION

Inventor： Pandurang V. Chouthaiwale ,  Fujie Tanaka

IPC: C07D309/28 ,  C07D407/04 ,  C07D307/54 ,  C07D241/44 ,  C07D317/30 ,  C07C205/55 ,  C07D243/02

CPC classification number: C07D309/28 ,  C07C201/14 ,  C07C205/55 ,  C07C2601/14 ,  C07D241/44 ,  C07D243/02 ,  C07D307/54 ,  C07D309/30 ,  C07D317/30 ,  C07D407/04

Abstract: Disclosed is a process for preparing dihydro-2H-pyran derivatives of formula I: wherein R1 and R2 are defined herein. The process of the invention provides the compound of formula I in concise cascade reactions and in one pot. The compound of formulae I prepared by the process of the invention and its further transformed derivatives are useful for making pharmaceutical composition for the treatment of proliferative diseases.

Abstract translation: 公开了制备式I的二氢-2H-吡喃衍生物的方法：其中R 1和R 2在本文中定义。 本发明的方法在简单的级联反应中和一锅中提供式I化合物。 通过本发明方法制备的式I化合物及其进一步转化的衍生物可用于制备用于治疗增殖性疾病的药物组合物。

公开(公告)号：US20150088480A1

公开(公告)日：2015-03-26

申请号：US14402932

申请日：2013-07-11

Applicant: OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION ,  THE SYSTEMS BIOLOGY INSTITUTE

Inventor： Yoshiyuki Asai ,  Takeshi Abe ,  Hiroaki Kitano ,  Masao Okita ,  Samik Ghosh ,  Yukiko Matsuoka

IPC: H04L29/08 ,  G06F17/50 ,  G06F17/30 ,  H04L12/18 ,  G06F9/48

CPC classification number: H04L67/10 ,  F04C2270/0421 ,  G06F9/4843 ,  G06F16/00 ,  G06F17/5009 ,  G06Q10/06 ,  G06Q10/10 ,  G06Q50/01 ,  G06Q50/22 ,  H04L12/1813

Abstract: A simulation system includes an interface component connected to a public or shared network that has less restrictive access than networks inside the firewall, generating a simulation job and registering the simulation job in a database, a job control component accessing said database to retrieve the simulation job and scheduling the simulation job for execution, and a simulation execution component receiving the simulation job from the job control component, creating executable codes for numerical and parallel computing algorithms and distributing computing processes to multiple computers to execute the simulation job.

Abstract translation: 模拟系统包括连接到公共或共享网络的接口组件，其具有比防火墙内的网络更少的限制性访问，生成模拟作业并将模拟作业注册在数据库中，作业控制组件访问所述数据库以检索模拟作业 并且调度所述模拟作业以执行，以及模拟执行组件，从所述作业控制组件接收所述模拟作业，为数字和并行计算算法创建可执行代码，并将计算过程分配给多个计算机以执行所述模拟作业。

公开(公告)号：US20130185644A1

公开(公告)日：2013-07-18

申请号：US13876283

申请日：2011-03-31

Applicant: Hiroaki Kitano ,  Yukiko Matsuoka ,  Samik Ghosh

Inventor： Hiroaki Kitano ,  Yukiko Matsuoka ,  Samik Ghosh

IPC: H04L12/24

CPC classification number: H04L41/22 ,  G06F17/30958 ,  G06F19/12 ,  G06F19/26 ,  G06F19/28

Abstract: The present invention involves retrieving edges that do not constitute a designated network model which is a network model designated by a user and are linked to nodes that constitute the designated network model, displaying retrieval results that include the retrieved edges and network model IDs corresponding to the edges in a selectable manner, and generating an integrated network model in which, when the retrieval results are selected by the user, the edges that are included in the selected retrieval results and the nodes that do not constitute the designated network model and are linked to the edges, are integrated into the designated network model.

Abstract translation: 本发明涉及检索不构成作为由用户指定的网络模型的指定网络模型的边缘，并且链接到构成指定网络模型的节点，显示包括检索到的边缘的检索结果和对应于该网络模型ID的网络模型ID 边缘，并且生成集成网络模型，其中当用户选择检索结果时，包括在所选择的检索结果中的边缘和不构成指定网络模型的节点被链接到 边缘被集成到指定的网络模型中。