公开(公告)号：US09415240B2

公开(公告)日：2016-08-16

申请号：US13536737

申请日：2012-06-28

Applicant: Petr Jordan ,  Andriy Myronenko ,  Jay B. West ,  Calvin R. Maurer, Jr. ,  Prashant Chopra ,  Anuj K. Purwar ,  Christopher A. Janko

Inventor： Petr Jordan ,  Andriy Myronenko ,  Jay B. West ,  Calvin R. Maurer, Jr. ,  Prashant Chopra ,  Anuj K. Purwar ,  Christopher A. Janko

IPC: A61N5/10 ,  A61B6/00 ,  A61B6/02

CPC classification number: A61N5/1037 ,  A61B6/022 ,  A61B6/025 ,  A61B6/4035 ,  A61B6/481 ,  A61B6/482 ,  A61B6/5205 ,  A61B6/5211 ,  A61B6/5223 ,  A61B6/583 ,  A61N5/1042 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/1081 ,  A61N5/1083 ,  A61N2005/1061 ,  A61N2005/1062

Abstract: Apparatus for generating multi-energy x-ray images and systems and methods for processing and using multi-energy x-ray images are provided for treating a target, e.g., a tumor, for image-guided radiation therapy. An image-guided radiation therapy system is provided including a treatment delivery system, a multi-energy imaging system, and a system processor. The treatment delivery system includes a radiation source configured to generate treatment radiation beams. The multi-energy imaging system is configured to generate a first set of image data of the patient using imaging radiation at a first energy level and a second set of image data of the patient using imaging radiation at a second energy level. The system processor is configured to process the first and second sets of image data to generate an enhanced image of the patient and to direct the treatment delivery system based on information obtained from the enhanced image.

Abstract translation: 用于产生多能量X射线图像的装置和用于处理和使用多能量X射线图像的系统和方法被提供用于治疗靶，例如肿瘤用于图像引导的放射治疗。 提供了一种图像引导放射治疗系统，包括治疗递送系统，多能量成像系统和系统处理器。 治疗递送系统包括被配置为产生治疗辐射束的辐射源。 多能量成像系统被配置为使用第一能级的成像辐射和使用第二能级的成像辐射的患者的第二组图像数据来产生患者的第一组图像数据。 系统处理器被配置为处理第一和第二组图像数据以生成患者的增强图像，并且基于从增强图像获得的信息来指导治疗传递系统。

公开(公告)号：US09392989B2

公开(公告)日：2016-07-19

申请号：US14451737

申请日：2014-08-05

Applicant: Siemens Aktiengesellschaft

Inventor： Susanne Dornberger ,  Thomas Mertelmeier ,  Ralf Nanke

IPC: A61B6/04 ,  A61B6/00 ,  A61B6/02

CPC classification number: A61B6/54 ,  A61B6/025 ,  A61B6/0414 ,  A61B6/4028 ,  A61B6/502 ,  A61B6/544

Abstract: In a mammography apparatus, a deflection of an x-ray source aligned on a radiation detector is predetermined depending on the size of a breast compressed in the compression unit and/or the density of the breast tissue. Given an increasing deflection on an arc-shaped trajectory of the x-ray source, the compression of the breast is reduced at least once so that the path of the x-rays through the breast stays within a predetermined path length, starting from a first compression in a first x-ray acquisition.

Abstract translation: 在乳房摄影装置中，根据在压缩单元中压缩的乳房的尺寸和/或乳房组织的密度，预先对准在放射线检测器上的X射线源的偏转。 鉴于x射线源的弧形轨迹上的偏移增加，乳房的压缩至少减少一次，使得通过乳房的x射线的路径停留在预定的路径长度内，从第一 在第一次X射线采集中的压缩。

公开(公告)号：US20160199666A1

公开(公告)日：2016-07-14

申请号：US15078553

申请日：2016-03-23

Applicant: ACCURAY INCORPORATED

Inventor： Calvin R. Maurer ,  Euan S. Thomson

IPC: A61N5/10 ,  A61B6/06 ,  A61B6/02 ,  A61B6/00 ,  A61B6/03

CPC classification number: A61N5/1039 ,  A61B5/0035 ,  A61B5/0059 ,  A61B5/055 ,  A61B6/025 ,  A61B6/032 ,  A61B6/06 ,  A61B6/4014 ,  A61B6/4085 ,  A61B6/4435 ,  A61B6/4452 ,  A61B6/488 ,  A61N5/10 ,  A61N5/1037 ,  A61N5/1042 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1065 ,  A61N5/1067 ,  A61N5/1081 ,  A61N5/1082 ,  A61N2005/1061 ,  A61N2005/1062 ,  A61N2005/1092 ,  G01N2223/308

Abstract: A method of image guided radiation treatment (IGRT) is described. The method may include receiving a pre-acquired image data set of the body part acquired in a reference frame generally independent of a reference frame of an IGRT apparatus, processing a first population of x-ray cone beam projection images to compute therefrom a first tomosynthesis image volume; and operating a radiation treatment head of the IGRT apparatus to deliver treatment radiation to the body part based at least in part on a comparison between the first tomosynthesis image volume a pre-acquired image data set of the body part.

Abstract translation: 描述了一种图像引导辐射治疗（IGRT）的方法。 该方法可以包括接收在通常独立于IGRT装置的参考帧的参考帧中获取的身体部位的预先获取的图像数据集，处理第一组x射线锥形束投影图像以从其计算第一次断层合成 图像体积; 以及操作所述IGRT装置的辐射治疗头，至少部分地基于所述身体部位的预先获取的图像数据集的第一体层合成图像体积之间的比较来将治疗辐射递送到所述身体部位。

公开(公告)号：US09387347B2

公开(公告)日：2016-07-12

申请号：US14539476

申请日：2014-11-12

Applicant: ACCURAY INCORPORATED

Inventor： Calvin R. Maurer, Jr.

IPC: A61N5/10 ,  A61B6/00 ,  A61B5/00 ,  A61B5/055 ,  A61B6/02 ,  A61B6/03

CPC classification number: A61N5/1039 ,  A61B5/0035 ,  A61B5/0059 ,  A61B5/055 ,  A61B6/025 ,  A61B6/032 ,  A61B6/06 ,  A61B6/4014 ,  A61B6/4085 ,  A61B6/4435 ,  A61B6/4452 ,  A61B6/488 ,  A61N5/10 ,  A61N5/1037 ,  A61N5/1042 ,  A61N5/1048 ,  A61N5/1049 ,  A61N5/1065 ,  A61N5/1067 ,  A61N5/1081 ,  A61N5/1082 ,  A61N2005/1061 ,  A61N2005/1062 ,  A61N2005/1092 ,  G01N2223/308

Abstract: Systems, methods, and related computer program products for image-guided radiation treatment (IGRT) are described. Provided according to one preferred embodiment is an IGRT apparatus including a barrel-style rotatable gantry structure that provides high mechanical stability, versatility in radiation delivery, and versatility in target tracking. Methods for treatment radiation delivery using the IGRT apparatus include conical non-coplanar rotational arc therapy and cono-helical non-coplanar rotational arc therapy. A radiation treatment head (MV source) and a treatment guidance imaging system including a kV imaging source are mounted to and rotatable with a common barrel-style rotatable gantry structure, or alternatively the MV and kV sources are mounted to separate barrel-style rotatable gantry structures independently rotatable around a common axis of rotation. Methods for intra-fraction target tracking in a gantry-style IGRT system based on comparisons between a pre-acquired planning image and intrafraction x-ray tomosynthesis images and/or intrafraction cone beam CT (CBCT) images are also described.

公开(公告)号：US09380990B2

公开(公告)日：2016-07-05

申请号：US14315838

申请日：2014-06-26

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Jong-pil Kim ,  Woo-sup Han

IPC: A61B6/04 ,  A61B6/00 ,  A61B6/02 ,  A61B6/03

CPC classification number: A61B6/502 ,  A61B6/025 ,  A61B6/032 ,  A61B6/0421 ,  A61B6/0435 ,  A61B6/4014 ,  A61B6/5205

Abstract: An apparatus for imaging a breast using an X-ray includes a support having a through-hole, a holder having a cylindrical shape, disposed in the through-hole of the support, and accommodating a breast of a patient, a linear X-ray generator disposed outside the holder and emitting an X-ray having a linear beam section that is lengthy in a vertical direction of the holder, a linear X-ray detector arranged outside the holder, and a rotation driver rotating the linear X-ray generator and the linear X-ray detector along an outer circumference of the holder.

Abstract translation: 使用X射线成像乳房的装置包括具有通孔的支撑体，具有圆柱形形状的保持器，设置在支撑件的通孔中，并容纳患者的乳房，线性X射线 发生器，其设置在所述保持器的外侧，并且发射具有在所述保持器的垂直方向上长度的线性束部分的X射线，设置在所述保持器的外侧的线性X射线检测器和旋转所述线性X射线发生器的旋转驱动器， 线性X射线检测器沿着保持器的外圆周。

公开(公告)号：US09380985B2

公开(公告)日：2016-07-05

申请号：US14147113

申请日：2014-01-03

Applicant: FUJIFILM Corporation

Inventor： Sadato Akahori

IPC: A61B6/03 ,  A61B6/02 ,  A61B6/00 ,  A61B6/04 ,  G06T11/00 ,  G06T7/20

CPC classification number: A61B6/032 ,  A61B6/025 ,  A61B6/0492 ,  A61B6/4233 ,  A61B6/4283 ,  A61B6/4452 ,  A61B6/4464 ,  A61B6/502 ,  A61B6/584 ,  A61B6/585 ,  A61B6/587 ,  A61B6/588 ,  G06T7/246 ,  G06T11/005 ,  G06T2207/10016 ,  G06T2207/10116 ,  G06T2207/30004 ,  G06T2207/30204 ,  G06T2207/30241

Abstract: The X-ray imaging device comprises an X-ray source that is able to move along a predetermined movement path, a movement unit configured to cause the X-ray source to move along the predetermined movement path, an imaging platform that is disposed to face the X-ray source, a flat-panel X-ray detector that is provided to the imaging platform, a marker that is disposed in the imaging platform, a control unit that causes the X-ray source to move and to capture images respectively including the marker from at least two positions, and an image processing unit that calculates a position of an image of the marker in each of the captured images and calculates a slope of a movement axis of the X-ray source with respect to the X-ray detector based on a relative relationship between positions of images of the marker.

Abstract translation: X射线成像装置包括能够沿着预定的移动路径移动的X射线源，被配置为使X射线源沿着预定的移动路径移动的移动单元，被配置为面对的成像平台 所述X射线源，设置在所述成像平台上的平板X射线检测器，设置在所述成像平台中的标记，使所述X射线源移动并且分别捕获图像的控制单元， 来自至少两个位置的标记，以及图像处理单元，其计算每个拍摄图像中的标记的图像的位置，并计算X射线源的X轴的移动轴的斜率 基于标记图像的位置之间的相对关系的检测器。

公开(公告)号：US20160183899A1

公开(公告)日：2016-06-30

申请号：US14984865

申请日：2015-12-30

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Laurence Vancamberg ,  Serge Louis Wilfrid Muller ,  Razvan Gabriel Iordache ,  Aurélie Boudier

IPC: A61B6/00 ,  A61B6/04

CPC classification number: A61B6/4458 ,  A61B6/025 ,  A61B6/0407 ,  A61B6/0414 ,  A61B6/0457 ,  A61B6/102 ,  A61B6/12 ,  A61B6/4429 ,  A61B6/4476 ,  A61B6/502 ,  A61B6/587 ,  A61B34/37 ,  A61B90/50 ,  A61N5/1083 ,  B25J9/0084 ,  B25J9/0087 ,  B25J9/06 ,  B25J9/1682 ,  G01N2223/321 ,  Y10S901/06 ,  Y10S901/16

Abstract: A device and a related mammography method employing the device are described. The device comprises an x-ray source, an x-ray detector placed under a support plate for supporting an object and arranged to detect the x-rays coming from the x-ray source after they have passed through the object, and a positioning assembly with an arm having multiple degrees of freedom which is a collaborative robot for positioning the x-ray source with respect to the support plate. A method for performing an imaging procedure, which includes placing an object of interest on the support plate; moving the x-ray source relative to the object of interest along a non-planar trajectory to avoid collision with the object; and activating the x-ray source and the x-ray detector so as to detect the x-rays coming from the x-ray source after they have passed through the object, thus obtaining a set of x-ray images.

Abstract translation: 描述了使用该装置的装置和相关的乳房摄影方法。 该装置包括x射线源，X射线检测器，放置在用于支撑物体的支撑板下方，并被布置成在X射线源穿过物体之后检测来自X射线源的X射线，以及定位组件 具有多个自由度的臂，其是用于相对于支撑板定位x射线源的协作机器人。 一种用于执行成像过程的方法，其包括将感兴趣对象放置在支撑板上; 沿着非平面轨迹相对于感兴趣对象移动x射线源以避免与物体的碰撞; 并且激活X射线源和X射线检测器，以便在X射线源通过物体之后检测来自X射线源的X射线，从而获得一组x射线图像。

公开(公告)号：US20160183887A1

公开(公告)日：2016-06-30

申请号：US14972316

申请日：2015-12-17

Applicant: FUJIFILM Corporation

Inventor： Hiroyuki TOBA

IPC: A61B6/02 ,  A61B6/00 ,  A61B10/02

CPC classification number: A61B6/025 ,  A61B6/022 ,  A61B6/0414 ,  A61B6/12 ,  A61B6/461 ,  A61B6/502 ,  A61B6/5223 ,  A61B6/582 ,  A61B10/0233 ,  A61B34/20 ,  A61B2010/0208 ,  A61B2010/045

Abstract: A position of a target designated based on a tomosynthesis image is identified as a first designated position. The first designated position is virtually projected to a radiation detector from two calibrated-stereotactic tube positions which have been calibrated into a tomosynthesis coordinate system so as to obtain two projection positions. The first designated position is converted into a second designated position in a stereotactic coordinate system based on stereotactic tube positions and the projection positions. A biopsy needle is inserted into a subject to be examined based on the second designated position. The biopsy needle is driven based on a biopsy coordinate system calibrated with respect to the stereotactic coordinate system.

Abstract translation: 将基于断层合成图像指定的目标的位置识别为第一指定位置。 第一指定位置被虚拟地投射到已经被校准到断层合成坐标系中的两个经校准的立体定向管位置的辐射检测器，以获得两个投影位置。 基于立体定向管位置和投影位置，第一指定位置被转换成立体定向坐标系中的第二指定位置。 基于第二指定位置将活检针插入待检查对象。 基于相对于立体定向坐标系校准的活检坐标系来驱动活检针。

公开(公告)号：US20160166218A1

公开(公告)日：2016-06-16

申请号：US14436519

申请日：2013-10-18

Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION

Inventor： Mark B. WILLIAMS ,  Zongyi GONG

IPC: A61B6/00 ,  A61B6/02

CPC classification number: A61B6/4258 ,  A61B6/025 ,  A61B6/0414 ,  A61B6/4417 ,  A61B6/481 ,  A61B6/502 ,  A61B6/5205 ,  A61B6/5247 ,  G06T11/006 ,  G06T2211/424

Abstract: A system and related methods for gamma emission breast tomosynthesis in which a set of two-dimensional images of a breast taken at different angular views are reconstructed into a three-dimensional map of the breast. The system applies an expectation maximization technique having integrated regularization, resolution recovery and attenuation correction to improve the clarity of the resulting three-dimensional map.

Abstract translation: 一种用于γ射线乳房断层合成的系统和相关方法，其中以不同角度视图拍摄的乳房的一组二维图像被重建成乳房的三维图。 该系统应用具有积分正则化，分辨率恢复和衰减校正的期望最大化技术，以提高所得到的三维地图的清晰度。

公开(公告)号：US20160128649A1

公开(公告)日：2016-05-12

申请号：US14899094

申请日：2014-06-18

Applicant: CANON KABUSHIKI KAISHA

Inventor： Nobu Miyazawa

IPC: A61B6/02 ,  A61B6/00

CPC classification number: A61B6/025 ,  A61B6/4452 ,  A61B6/463 ,  A61B6/465 ,  A61B6/467 ,  A61B6/5205 ,  A61B6/5211 ,  A61B6/54 ,  A61B6/545 ,  A61B6/563

Abstract: In tomosynthesis imaging for obtaining a tomosynthesis image from a projected image group captured by irradiating an object with X-rays from a plurality of different angles by using an X-ray generation unit and an X-ray detection unit, whether or not to cause a new icon corresponding to set process conditions to be displayed on a display unit is controlled in accordance with process conditions set by a condition setting unit 4051 and process conditions corresponding to a tomosynthesis image already generated by an image processing unit 110.

Abstract translation: 在通过使用X射线产生单元和X射线检测单元从多个不同角度通过用X射线照射物体而获取的投影图像组获得断层合成图像的层析合成成像中，是否引起 根据由条件设置单元4051设置的处理条件和与图像处理单元110已经生成的断层图像相对应的处理条件来控制对应于设置要显示在显示单元上的处理条件的新图标。