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公开(公告)号：US4533358A
公开(公告)日：1985-08-06
申请号：US632855
申请日：1984-07-20
Applicant: Yoshimasa Yoden , Tsuneo Okuda , Eiji Fuchigami , Toshihiro Kuwabara
Inventor： Yoshimasa Yoden , Tsuneo Okuda , Eiji Fuchigami , Toshihiro Kuwabara
Abstract: A process for producing a shaped product of collagen by a wet or electrochemical method from a pasty composition comprising a collagenous substance or a mixture thereof with another high molecular substance. The composition or a product shaped therefrom is treated with a crosslinking agent, and the shaped product is frozen, and thawed.
Abstract translation: 通过湿法或电化学方法从包含胶原物质或其混合物的糊状组合物制备胶原形成产物的方法。 将该组合物或由其成形的产品用交联剂处理，并将成形产品冷冻并解冻。
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92.发明授权Preparation of hydrolyzed collagen-containing products from non-gelled, liquid hydrolyzed collagen concentrate and gelled products prepared therefrom 失效从非凝胶化的液体水解胶原浓缩物和由其制备的凝胶产物制备含水解胶原的产品
公开(公告)号：US4426443A
公开(公告)日：1984-01-17
申请号：US295796
申请日：1981-08-27
Applicant: Joseph L. Shank
Inventor： Joseph L. Shank
IPC: A23L29/281 , C09H5/00 , C09K3/22 , D21H17/22 , G03C1/047 , G03C1/93 , B05D3/02 , B05D7/00 , C08L89/06
Abstract: A method of preparing a gelled product from an ungelled aqueous hydrolyzed collagen, such as gelatin or glue, concentrate containing 10-60 weight percent hydrolyzed collagen and a lyotropic agent is disclosed. The concentrate has a hydrolyzed collagen-to-lyotropic agent weight ratio of 1:0 of 1:0.1 to about 1:4.5, a pH value of 2.5-7 and gels at less than 20.degree. C. On dilution with water to a hydrolyzed collagen concentration of about 2 weight percent while substantially maintaining the pH value of the concentrate, the diluted composition gels at a temperature above that of the concentrate. Specific concentrates, food products, industrial applications and methods for using the concentrates are disclosed.
Abstract translation: 公开了一种从未胶凝的水解胶原蛋白（例如明胶或胶水）制备含有10-60重量％水解胶原和溶致剂的浓缩物的方法。 该浓缩物的水解胶原与溶血剂的重量比为1:0.1至约1:4.5，pH值为2.5-7，凝胶在小于20℃。在用水稀释至水解 胶原浓度为约2重量％，同时基本上保持浓缩物的pH值，稀释的组合物在高于浓缩物的温度下凝胶化。 公开了特定浓缩物，食品，工业应用和使用浓缩物的方法。
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93.发明授权Procedures for preparing composite materials from collagen and glycosaminoglycan 失效从胶原和糖胺聚糖制备复合材料的程序
公开(公告)号：US4350629A
公开(公告)日：1982-09-21
申请号：US287998
申请日：1981-07-29
Applicant: Ioannis V. Yannas , Martin J. Forbes
Inventor： Ioannis V. Yannas , Martin J. Forbes
IPC: A61F2/00 , A61L27/24 , A61L27/26 , A61L33/00 , A61L33/12 , C08L89/06 , C07G7/00 , C08H1/00 , C08H1/06
CPC classification number: A61L33/122 , A61L27/24 , A61L27/26 , A61L33/0011 , C08L89/06 , A61F2310/00365 , Y10S128/08
Abstract: This invention relates to crosslinked collagen and glycosaminoglycan materials, and to procedures for preparing such materials. It has been discovered that if collagen fibrils in an aqueous acidic solution are contacted with a crosslinking agent before being contacted with glycosaminoglycan, the materials produced have extremely low levels of thrombogenicity. Such materials are well suited for in-dwelling catheters, blood vessel grafts, and other devices that are in continuous contact with blood for long periods of time.
Abstract translation: 本发明涉及交联胶原和糖胺聚糖材料，以及制备这些材料的方法。 已经发现，如果将酸性水溶液中的胶原纤维在与糖胺聚糖接触之前与交联剂接触，则所生产的材料具有非常低的血栓形成水平。 这种材料非常适用于长时间与血液持续接触的住宅导管，血管移植物和其他装置。
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公开(公告)号：US4271070A
公开(公告)日：1981-06-02
申请号：US147063
申请日：1980-05-05
Applicant: Teruo Miyata , Albert L. Rubin , Kurt H. Stenzel
Inventor： Teruo Miyata , Albert L. Rubin , Kurt H. Stenzel
CPC classification number: C07K14/78 , A61L15/325 , A61K38/00 , A61L2400/04 , Y10S128/08 , Y10S530/84
Abstract: Chemically-modified quaternary-structured fiber collagens of minimum molecular length, diameter and periodicity, and containing a relatively high positive electrostatic charge are claimed as hemostatic agents. Specific examples are guanidinated, esterified, and guanidinated-esterified collagen fibers of the type described.
Abstract translation: 作为止血剂要求具有最小分子长度，直径和周期性并且含有相对高的正静电电荷的化学修饰的四元结构纤维胶原。 具体实例是所述类型的胍化，酯化和胍化 - 酯化的胶原纤维。
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公开(公告)号：US4260228A
公开(公告)日：1981-04-07
申请号：US113856
申请日：1980-01-21
Applicant: Teruo Miyata
Inventor： Teruo Miyata
CPC classification number: C08K5/053
Abstract: An improved collagen gel soft contact lens is prepared from an aldehyde-crosslinked, lens-shaped collagen gel containing a water-soluble, aliphatic, monomeric, polyhydroxy compound, e.g., glucose.
Abstract translation: 由含有水溶性，脂肪族，单体，多羟基化合物（例如葡萄糖）的醛交联的晶状体胶原凝胶制备改进的胶原凝胶软性隐形眼镜。
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Patent Agency Ranking
公开(公告)号：US3806350A
公开(公告)日：1974-04-23
申请号：US21383271
申请日：1971-12-29
Applicant: FREUDENBERG C
CPC classification number: A22C13/0016 , C08L89/06
Abstract: AQUEOUS SWOLLEN COLLAGEN OF DOUGH--LIKE CONSISTENCY IS RAISED IN PH WHEREUPON IT DE-SWELLS OR SHRINKS. FIBER REINFORCEMENT CAN THEN BE STIRRED INTO THE AQUEOUS PHASE. UPON RE-ACIDFICATION, THE COLLAGEN AGAIN SWELLS WITH THE FIBER RE-INFORCEMENT DISTRIBUTED SUBSTANTIALLY UNIFORMLY THERETHROUGH. IF DESIRED, A DISPERSION OF AN ESTER OF POLYACRYLIC ACID OR POLYVINYLIDENE CHLORIDE CAN BE INCORPORATED IN THE MASS, PREFERABLY BEFORE RE-SWELLING. THE PRODUCT CAN THEN BE SHAPED IN KNOWN MANNER, AS BY EXTRUSION, AND DE-WATERED AS BY COAGULATION AND/OR DRYING.
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公开(公告)号：US3223551A
公开(公告)日：1965-12-14
申请号：US25622563
申请日：1963-02-05
Applicant: UNITED SHOE MACHINERY CORP
Inventor： SHU-TUNG TU
IPC: C08L89/06
CPC classification number: C08L89/06 , Y10S428/904 , Y10T428/268
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公开(公告)号：US3178301A
公开(公告)日：1965-04-13
申请号：US5664660
申请日：1960-09-19
Applicant: ARMOUR & CO
Inventor： ARTHUR VEIS , JEROME COHEN
CPC classification number: D01F4/00 , A22C13/0016 , C08H1/06 , C08L89/06 , C09H3/00 , Y10S530/842
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100.发明授权Sheet comprising leather fibers, ethylene oxide-dicyandiamide condensation product and rubber latex and process for preparing same 失效包含皮革纤维，环氧乙烷 - 双氰胺缩合产物和橡胶胶乳的片及其制备方法
公开(公告)号：US2948692A
公开(公告)日：1960-08-09
申请号：US65622257
申请日：1957-05-01
Applicant: MICHIGAN RES LAB INC , ELECTRO CHEM FIBER SEAL CORP
Inventor： PATTILLOCH DONALD K , CARL POLOWCZYK
CPC classification number: D21H5/1209 , C08L7/02 , C08L11/02 , C08L89/06 , D21H13/34 , Y10S524/925 , C08L2666/26
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