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    SELF-RETAINING SUTURES OF POLY-4-HYDROXYBUTYRATE AND COPOLYMERS THEREOF
    94.
    发明申请
    SELF-RETAINING SUTURES OF POLY-4-HYDROXYBUTYRATE AND COPOLYMERS THEREOF 有权

    公开(公告)号：US20220354988A1

    公开(公告)日：2022-11-10

    申请号：US17870619

    申请日：2022-07-21

    申请人： Tepha, Inc.

    发明人： Said Rizk ,  Simon F. Williams

    IPC分类号： A61L17/10 ,  A61B17/06 ,  A61L27/18 ,  A61L31/06

    摘要： Absorbable monofilament fibers and self-retaining sutures with high tensile strengths have been developed. The straight pull tensile strengths of the absorbable self-retaining sutures closely approximate, equal or exceed the average minimum knot-pull tensile standards set by the United States Pharmacopeia (USP). These higher strength absorbable self-retaining sutures can therefore be used either without needing to oversize the suture for a given procedure, or by oversizing the self-retaining suture by no more than 0.1 mm in diameter. In one embodiment, the absorbable self-retaining sutures are made from poly-4-hydroxybutyrate or copolymers thereof.

    Small diameter, high strength, low elongation, creep resistant, abrasion resistant braided structure
    96.
    发明授权
    Small diameter, high strength, low elongation, creep resistant, abrasion resistant braided structure 有权

    公开(公告)号：US11427958B2

    公开(公告)日：2022-08-30

    申请号：US16923183

    申请日：2020-07-08

    申请人： ATEX Technologies, Inc.

    发明人： Mark Wesley Jessup ,  Paul Louis Van Hulle

    IPC分类号： D07B1/04 ,  D07B1/02 ,  A61L17/10 ,  A61L27/50 ,  A61L27/18 ,  A61L17/14

    摘要： A braided structure that includes a core and a sheath is provided. The core includes a yarn formed at least in part from an aromatic polymer (e.g., an aromatic polyester/liquid crystalline polymer or an aramid polymer), and the sheath, which includes a plurality of ultra high molecular weight polyolefin yarns, is braided around the core. The sheath has an overall diameter ranging from about 60 micrometers to about 650 micrometers. Despite its small diameter, the braided structure can be creep resistant and abrasion resistant while at the same time exhibiting low elongation, a high load at break, and high stiffness. The braided structure can be used in medical applications such as sutures, load bearing orthopedic applications, artificial tendons/ligaments, fixation devices, actuation cables, components for tissue repair, etc.

    Microfluidic extrusion
    97.
    发明授权
    Microfluidic extrusion 有权

    公开(公告)号：US11338056B2

    公开(公告)日：2022-05-24

    申请号：US17328633

    申请日：2021-05-24

    申请人： Embody, Inc.

    发明人： Michael P. Francis ,  Stella Petrova ,  Nicholas Thayer

    IPC分类号： A61L27/24 ,  A61L27/38 ,  A61L17/10 ,  A61L17/14 ,  D01D5/06 ,  D01D5/02 ,  D01D5/38 ,  D01D7/00 ,  D01F4/00

    摘要： A method for supporting repair of soft tissue with biopolymer fibers. Biopolymer is dissolved in acid in a closed container made of materials inert to the acid and to the collagen to form a biopolymer solution. The solution is stirred, then centrifuged to degas it. The degassed solution is put into syringes on a holder. The number of syringes equals the number of fibers in the bundle. The syringes are mounted in a rotatable holder. Essentially equal quantities of degassed solution are extruded from the syringes to produce fibers, which are gathered and fed into a formation buffer bath. The fibers are kept taught after extrusion and dehydrated in a dehydrating solution in a dehydrating bath. The fibers are wound a collector to collect the bundle. The fibers are used to support repair of soft tissue.