摘要:
2,3-Dihydrofurans having highly desirable odor characteristics closely mimicking that of natural products are provided herein. The 2,3-dihydrofurans correspond to the formula ##STR1## wherein R' is an alkyl group having from 1 to 4 carbon atoms, R** is an alkyl group having from 1 to 5 carbon atoms, R.sub.1 is an alkyl group having from 1 to 4 carbon atoms, R.sub.2 is hydrogen or an alkyl group having from 1 to 6 carbon atoms, and R.sub.3 and R.sub.4 are hydrogen or a methyl group. The 2,3-dihydrofuran compounds are useful in the preparation of fragrance compositions and fragranced articles and can be employed in conjunction with known fragrance materials to augment or enhance the aromas thereof.
摘要:
This application relates to a stereospecific process for preparing specific enantiomers of 4-amino-4,5-dihydro-2-furancarboxylic acid and C.sub.1-6 lower alkyl esters thereof. These compounds are .gamma.-aminobutyric acid transaminase inhibitors useful in the treatment of epilepsy.
摘要:
N-Acylated N-phenyl-aminotetrahydro-2-furanones of the formula ##STR1## wherein R represents C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy or halogen,R.sub.1 represents C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.4 -alkoxy or halogen,R.sub.2 represents hydrogen, C.sub.1 -C.sub.3 -alkyl, C.sub.1 -C.sub.4 -alkoxy or halogen,R.sub.3 represents hydrogen or methyl, with the total number of C atoms of the substituents R, R.sub.1, R.sub.2 and R.sub.3 in the phenyl ring not exceeding the number 8,R.sub.4 represents hydrogen or methyl, whileR.sub.5 represents one of the following groups: an alkylthioalkyl or alkoxyalkyl group having 2 to 5 carbon atoms or an alkoxyalkoxymethyl group having a maximum of 6 carbon atoms, a 2-furanyl or 2-tetrahydrofuranyl group optionally substituted by halogen, a 1,2,4-triazolylmethyl group, a 1,2-pyrazolylmethyl group, or a group --CH.sub.2 --OR.sub.6 in which R.sub.6 represents a 5- or 6-membered heterocycle having oxygen as the hetero atom.are valuable fungicidal active substances. They can be used as fungicidal compositions, particularly for combating phytopathogenic fungi, e.g. against downy mildew on potatoes, tomatoes, grape vines and sugar beet and other plants. The novel compounds have a systemic action.
摘要:
The invention relates to a novel fluorinated pre-polymer and novel process steps in producing the same. The pre-polymers are quinoxaline materials derived by reaction of diketone linkage containing perfluoro-compounds with an aromatic diamine. The diketone is produced by oxidatively dechlorinating a polychloroketone which may be a monoketone or a bis-ketone. The polychloroketone is produced by reacting a keto-ylid with a chlorinating agent, e.g., chlorine. The keto-ylid is produced by reacting a phosphorane with an acid halide of a polyoxy-perfluoroalkylene oxide wherein the perfluoro-oxyalkylene group contains two or three carbon atoms, and there are present from two to twenty perfluoro-oxyalkylene units in the oligomer. The quinoxalines, the polychloroketones and the diketones hereof are novel products. Cross-linking may be effected with a free radical generator.
摘要:
A compound of the formula: ##STR1## wherein R.sub.1 and R.sub.2 are, same or different, each a hydrogen atom, a C.sub.1 -C.sub.3 alkyl group optionally substituted with halogen, an alkoxyalkyl or alkylthioalkyl group of the formula: R.sub.7 --Z--(CH.sub.2).sub.q --, a C.sub.2 -C.sub.3 alkenyl group, a C.sub.2 -C.sub.4 alkynyl group, a C.sub.1 -C.sub.2 alkoxy group, a C.sub.1 -C.sub.2 alkylthio group, a phenyl group, a pyridyl group, a furyl group or a thienyl group, or R.sub.1 and R.sub.2 may be combined together to form a saturated or unsaturated 5- or 6-membered ring having 0 to 2 oxygen or sulfur atom(s) within the ring, R.sub.3 and R.sub.4 are, same or different, each a hydrogen atom or a methyl group, R.sub.5 is a methyl group or a halogen atom, R.sub.6 is a C.sub.1 -C.sub.4 alkyl group, a methoxy group, a halogen atom, a trifluoromethyl group or a nitro group, R.sub.7 is a methyl group or an ethyl group, X is an oxygen atom, a sulfur atom or a methylene group, Y and Z are each an oxygen atom or a sulfur atom, l is an integer of 0 to 5, m is an integer of 0 to 4, n is an integer of 0 to 2 and q is an integer of 1 or 2, which is useful as an insect controlling agent.
摘要:
Compounds of the formula ##STR1## in which Ar is 2-alkyl-, -alkoxy- or -halo-methyl-phenyl or .alpha.-naphthyl, each of which is further substituted,R.sub.1 is 2-furyl, 2-tetrahydrofuryl, alkenyl, cyclopropyl, .beta.-alkoxyethyl, hydroxymethyl, triazolylmethyl, imidazolylmethyl, pyrazolylmethyl, alkylsulfinyl, alkylsulfonyl, alkoxy, alkenyloxy, alkynyloxy, alkylthio, alkenylthio, alkynylthio, alkylsulfinyloxy, dialkylaminosulfinyloxy, phosphoric or thiophosphoric esters or amides, or alkylcarbonyloxy, andR.sub.9 is hydrogen or methyl,are microbicidally, in particular fungicidally active. The preferred compounds are those in which Ar is 2-methylphenyl, 2-methoxyphenyl, 2-chlorophenyl or .alpha.-naphthyl, each of which is further substituted by azido, and R.sub.9 is hydrogen.
摘要:
Novel thioether compounds are disclosed which are useful as flavoring materials to enhance or impart meat-like flavors to foodstuffs. These compounds have the general formula ##STR1## where X can be, under specified conditions, --CH.sub.2 --, oxygen, or sulfur, Y can be oxygen or sulfur and R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are hydrogen or 1 to 3 carbon alkyl groups.
摘要:
N.sub.1 -acyl-N.sub.2 -phenyl-1,3-diaminopropan-2-ols are disclosed which possess ulcer-inhibiting activities.Further disclosed are pharmaceutical compositions which are effective in the treatment and prophylaxis of ulcers and which comprise as a pharmacologically active ulcus-inhibiting ingredient N.sub.1 -acyl-N.sub.2 -phenyl-1,3-diaminopropan-2-ols, or a pharmaceutically acceptable acid addition salt thereof, and a pharmaceutically acceptable diluent.Further disclosed are processes for the preparation of the N.sub.1 -acyl-N.sub.2 -phenyl-1,3-diaminopropan-2-ols.
摘要:
Production of 2-methylpyridin-3-ol derivatives including pyridoxine derivatives and pyridoxine (vitamin B.sub.6) itself by reaction of 4-methyloxazole with derivatives of 1,4-disubstituted but-2-en-2-ylsulfones in the manner of a Diels-Alder reaction.
摘要:
A heat curable composition comprises (1) an ether or an ester of an alcohol of the formula where n is 1 or 2 and (2) an amine having at least two nitrogen bonded hydrogen atoms. The esters (1) generally contain another five-or six-membered ring. Specified compounds (1) are 3,4 - dihydro - 1,2 - pyranyl - 2 - methyl-3,4 - dihydro - 1,2 - pyran - 2 - carboxylate; 3,4 - dihydro - 1,2 - pyran - 2 - methyl - 2,3-dihydrothiophene - 2 - carboxylate; 3,4 - dihydro - 1,2 - pyran - 2 - methyl - N - methyl-2,3 - dihydropyrrole - 2 - carboxylate; 3,4-dihydro - 1,2 - pyran - 2 - methyl - 2,3 - dihydrofuran - 2 - carboxylate; dimethyldi - (3,4-dihydro - 1,2 - pyran - 2 - methoxy) silane; tri-(3,4 - dihydro - 1,2 - pyran - 2 - methyl) ether. Examples of amines are metaphenylene diamine, methylene dianiline, diaminodiphenylsulphone, triethylenetetramine, di - (hexamethylene) triamine, 1,3 - diamino-(methyl) cyclohexane and 1,3 - diaminocyclohexane. The composition is prepared by mixing the two components together with or without a solvent. Suitable amounts of amine are 0.8 to 1.5 equivalents per ethylenic group adjacent to the heteroatom. Other materials, e.g. fillers, dyes, plasticizers, stabilizers, vinyl resins, tars, pitches, distillate oils and alkyd resins may be added. Resinification is by heating to 90 DEG to 250 DEG C., accelerators or catalysts may be added. Uses.-Laminates, adhesives, mouldings and surface coating compositions.