公开(公告)号：US10408673B2

公开(公告)日：2019-09-10

申请号：US15706440

申请日：2017-09-15

Applicant: STC.UNM

Inventor： Steven R. J. Brueck ,  Alexander Neumann ,  Payman Zarkesh-Ha

IPC: G01J5/02 ,  G01J1/06 ,  G01J3/02 ,  G01J1/44 ,  G01J3/18 ,  G01J3/28 ,  G02B6/122 ,  G02B6/124 ,  H01L27/144 ,  H01L31/02 ,  H01L31/0216 ,  H01L31/0232 ,  H01L31/103 ,  G02B6/12

Abstract: A 2-D sensor array includes a semiconductor substrate and a plurality of pixels disposed on the semiconductor substrate. Each pixel includes a coupling region and a junction region, and a slab waveguide structure disposed on the semiconductor substrate and extending from the coupling region to the region. The slab waveguide includes a confinement layer disposed between a first cladding layer and a second cladding layer. The first cladding and the second cladding each have a refractive index that is lower than a refractive index of the confinement layer. Each pixel also includes a coupling structure disposed in the coupling region and within the slab waveguide. The coupling structure includes two materials having different indices of refraction arranged as a grating defined by a grating period. The junction region comprises a p-n junction in communication with electrical contacts for biasing and collection of carriers resulting from absorption of incident radiation.

公开(公告)号：US20190242897A1

公开(公告)日：2019-08-08

申请号：US16270306

申请日：2019-02-07

Applicant: STC.UNM

Inventor： Tione Buranda ,  Jacob Ongudi Agola ,  Soumik BasuRay ,  Scarlett Swanson ,  Angela Wandinger-Ness ,  Peter C. Simons ,  Virginie Bondu

IPC: G01N33/573 ,  G01N33/86

CPC classification number: G01N33/573 ,  G01N33/86 ,  G01N2333/914 ,  G01N2800/224 ,  G01N2800/26

Abstract: In one embodiment, the invention provides a method of diagnosing sepsis or a virus-related infection (often a viral hemorrhagic fever infection) in a subject by detecting and measuring the level of a set of sepsis and virus infection-associated-GTPase biomarkers in a sample obtained from the subject using multiplexed flow cytometry. Related kits are also provided. In a preferred embodiment, the invention provides point of care diagnostic methods for determining an early stage sepsis or the severity of a virus infection, especially in a hospital or other setting.

公开(公告)号：US10370305B1

公开(公告)日：2019-08-06

申请号：US15681981

申请日：2017-08-21

Applicant: STC.UNM

Inventor： Mahmoud Reda Taha ,  John Stormont ,  Edward N. Matteo

IPC: C04B41/45 ,  C04B41/49 ,  C04B41/48 ,  C04B41/50 ,  C09K8/44 ,  C09K8/42 ,  E21B33/138 ,  C04B111/34 ,  C04B111/00

Abstract: The present invention concerns compositions and methods of using the same that provide encapsulated polymer nanocomposites for efficient crack repair and monitoring of a cement-substrate interface.

公开(公告)号：US10366253B2

公开(公告)日：2019-07-30

申请号：US15534116

申请日：2015-12-15

Applicant: STC.UNM

Inventor： James Plusquellic

IPC: G06F21/73 ,  G06F21/70 ,  G06F21/60 ,  G06F21/71 ,  G09C1/00 ,  H04L9/32 ,  G06F17/18

Abstract: A Hardware-Embedded Delay Physical Unclonable Function (“HELP PUF”) leverages entropy by monitoring path stability and measuring path delays from core logic macros. Reliability and security enhancing techniques for the HELP PUF reduce bit flip errors during regeneration of the bitstring across environmental variations and improve cryptographic strength along with the corresponding difficulty of carrying out model building attacks. A voltage-based enrollment process screens unstable paths on normally synthesized (glitchy) functional units and reduces bit flip errors by carrying out enrollment at multiple supply voltages controlled using on-chip voltage regulators.

公开(公告)号：US10345486B2

公开(公告)日：2019-07-09

申请号：US15877167

申请日：2018-01-22

Applicant: STC.UNM

Inventor： Anthony Robert Menicucci ,  Thomas P. Caudell ,  Andrea A. Mammoli

IPC: G01W1/10 ,  G01J5/00 ,  H02J3/00 ,  G06Q10/04 ,  G06Q50/06 ,  H02J3/38 ,  G01J1/42

Abstract: The present invention is an apparatus and method of forecasting solar energy irradiance potential and subsequent photovoltaic output in a region. The apparatus and method includes collecting meteorological data for a given region and then estimating irradiance levels using parameters collected from the meteorological data. Solar energy production is then simulated using the collected meteorological data, estimated irradiance levels, and physical characteristics of a solar generating system in the given region at a predetermined time.

公开(公告)号：US10337186B2

公开(公告)日：2019-07-02

申请号：US15528459

申请日：2015-11-20

Applicant: STC.UNM

Inventor： Mahmoud Reda Taha ,  Eslam Mohamed Soliman

IPC: E04C5/07 ,  B32B5/12 ,  B32B5/00 ,  B32B5/26 ,  B32B5/22

Abstract: The present invention provides a fiber reinforced polymer composite having a plurality of layers containing a plurality of fibers. The layers may be configured to maintain predetermined load sharing ratios among the layers at different load levels to produce a gradual load transfer between the different layers during the progressive failure of the composite. The composite is comprised of mono-fibers and the load sharing ratios of the layers have coefficients of variation that are less than 20%.

公开(公告)号：US10329614B2

公开(公告)日：2019-06-25

申请号：US14909582

申请日：2014-08-01

Applicant: STC.UNM ,  Jeremy Scott Edwards

Inventor： Jeremy Scott Edwards

IPC: C12Q1/68 ,  C12Q1/6874 ,  C12Q1/6825 ,  C12Q1/6841

Abstract: This disclosure describes, in one aspect, methods for DNA sequencing and performing epigenomic analyses. Generally, the methods include immobilizing a plurality of copies of a DNA molecule on a surface, stretching at least a portion of the immobilized DNA molecules, and sequencing at least a portion of the immobilized, stretched DNA molecules.

公开(公告)号：US10299707B2

公开(公告)日：2019-05-28

申请号：US15489828

申请日：2017-04-18

Applicant: STC.UNM

Inventor： John B. Plumley ,  Erin D. Milligan ,  Marek Osinski

IPC: A61B5/1455 ,  G01N33/58 ,  A61B5/1459 ,  A61B5/00 ,  A61B5/1473

Abstract: The invention provides a quantum dot (QD) modified optical fiber-based biosensor which characterizes matrix metalloproteinase (MMP) enzyme activity at pain signaling sites in the central nervous system (CNS) in vivo. Related systems and peptide biomarker screening methods are also provided.

公开(公告)号：US20190134170A1

公开(公告)日：2019-05-09

申请号：US16250514

申请日：2019-01-17

Applicant: THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. HEALTH AND HUMAN SERVICES ,  STC.UNM

Inventor： Alan Remaley ,  John T. Schiller ,  Marcelo Amar ,  Bryce Chackerian

IPC: A61K39/00 ,  C07K11/00 ,  A61P9/10 ,  A61K38/10 ,  C12N9/64 ,  A61K45/06 ,  A61K47/69

Abstract: A vaccine construct comprising an antigenic PCSK9 peptide and an immunogenic carrier, and methods of using the same that are effective to lower blood cholesterol levels in a mammal and treat dyslipidemias and related disease states in a mammal without the frequency of administration required by passive immunity strategies.

公开(公告)号：US20190116797A1

公开(公告)日：2019-04-25

申请号：US16192248

申请日：2018-11-15

Applicant: University of Florida Research Foundation, Inc. ,  STC.UNM

Inventor： David G. Whitten ,  Kirk S. Schanze ,  Anand Parthasarathy ,  Eunkyung Ji ,  Motokatsu Ogawa ,  Thomas S. Corbitt ,  Dimitri Dascier ,  Ying Wang ,  Linnea K. Ista ,  Eric H. Hill

IPC: A01N43/90 ,  C08G61/02 ,  C07D409/14 ,  C08G75/00 ,  A01N25/08 ,  A01N33/10 ,  C07C217/14 ,  A01N25/10 ,  A01N33/12 ,  A01N41/04 ,  A01N43/10 ,  C08G61/12 ,  C07D487/08 ,  C07D333/16 ,  C07C309/24 ,  C07C217/20 ,  C07C309/11

Abstract: The present disclosure provides novel poly(phenylene ethynylene) (PPE) compounds, methods for synthesizing these compounds, and materials and substances incorporating these compounds. The various PPEs show antibacterial, antiviral and antifungal activity.