公开(公告)号：US5334294A

公开(公告)日：1994-08-02

申请号：US923800

申请日：1992-09-04

申请人： Hirohisa Iwai ,  Kaisuke Shiroyama ,  Akira Matsuda ,  Takeo Nakamura ,  Ryotomo Shirakawa

发明人： Hirohisa Iwai ,  Kaisuke Shiroyama ,  Akira Matsuda ,  Takeo Nakamura ,  Ryotomo Shirakawa

IPC分类号： A61M25/09 ,  B23H3/00 ,  B23H9/00 ,  B23H9/18 ,  C25F3/02 ,  C25F3/12 ,  C25F3/14 ,  C25F7/00

CPC分类号： B23H9/18 ,  B23H9/005 ,  A61M25/09

摘要： The present invention relates to a processing method of wire material and a processing device therefor at the times of intending to make the tip of wire materials such as guide wire for catheter thin and flexible by tapering.When the wire material passes through the electrolytic tub, the wire speed is made constant and the current value is controlled, or the current value is made constant and the wire speed is controlled to give the processings such as tapering. For the electrolytic polishing bath, it is desirable to use a mixed bath comprising trivalent alcohol, perchloric acid and monovalent alcohol.The inventive method exerts an effect that the tapering can be given efficiently and yet with high precision compared with the traditional method of mechanical polishing or the method of dipping one by one batchwise into the electrolytic polishing bath.

摘要翻译： PCT No.PCT / JP91 / 00027 Sec。 371日期：1992年9月4日 102（e）日期1992年9月4日PCT 1991年1月16日PCT PCT。 第WO92 / 12819号公报 日期：1992年8月6日。本发明涉及一种线材加工方法及其处理装置，其目的在于使导线材料的尖端如导管的导丝通过锥形变薄和柔性。 当导线材料通过电解槽时，使线速度恒定并且控制电流值，或者使电流值恒定并且控制线速度以给出诸如锥形的处理。 对于电解抛光浴，需要使用包含三价醇，高氯酸和一价醇的混合浴。 与传统的机械抛光方法相比，本发明的方法发挥了一种效果，与传统的机械抛光方法相比，可以有效地高精度地提供锥形化，或者将其逐个浸入电解抛光浴中。

公开(公告)号：US5258212A

公开(公告)日：1993-11-02

申请号：US690265

申请日：1991-04-24

申请人： Kazuhiko Tomaru ,  Akira Matsuda ,  Noboru Shimamoto

发明人： Kazuhiko Tomaru ,  Akira Matsuda ,  Noboru Shimamoto

IPC分类号： F16J15/10 ,  C08J9/32 ,  C08K7/22 ,  C08L83/05 ,  C08L83/07 ,  C09K3/10 ,  G11B33/08 ,  G11B33/12 ,  G11B33/14 ,  C08K5/24 ,  B65D81/02

CPC分类号： G11B33/1466 ,  C08K7/22 ,  G11B33/08 ,  Y10T428/1376 ,  Y10T428/1386 ,  Y10T428/23 ,  Y10T428/233 ,  Y10T428/249953 ,  Y10T428/249958 ,  Y10T428/249971 ,  Y10T428/249975 ,  Y10T428/249977 ,  Y10T428/249979 ,  Y10T428/31663

摘要： An improvement is proposed in the assemblage of a cover-packing bult-up body for a magnetic hard-disc unit to be freed from the troubles caused by dusts or contamination of the gap space between the magnetic recording disc and the magnetic head as well as by the poor vibration-damping characteristics of the rubber packing between the covering member and the body of the casing. The improvement comprises, instead of using a pre-shaped rubber packing, the built-up body is assembled by using a curable liquid silicone rubber-based composition filled with fine hollow microspheres to form a packing on the surface of the covering member by the in situ curing of the composition applied thereto so that the rubbery packing layer has a spongy structure exhibiting good vibration-damping characteristics.

摘要翻译： 在用于磁性硬盘单元的覆盖包装堆叠体的组合中提出了一种改进，以免由磁记录盘和磁头之间的间隙的灰尘或污染引起的麻烦以及 由于覆盖部件与壳体之间的橡胶垫圈的阻尼特性差。 改进之处在于，代替使用预成型橡胶填料，通过使用填充有细小的中空微球的可固化液体硅橡胶基组合物来组装积体，以通过在内部的内部形成覆盖构件的表面上的填料 施加到其上的组合物的原位固化，使得橡胶填充层具有显示出良好的阻尼特性的海绵结构。

公开(公告)号：US5047520A

公开(公告)日：1991-09-10

申请号：US295948

申请日：1988-11-18

申请人： Akira Matsuda ,  Tohru Ueda ,  Kenji Takenuki ,  Haruhiko Machida

发明人： Akira Matsuda ,  Tohru Ueda ,  Kenji Takenuki ,  Haruhiko Machida

IPC分类号： C07H19/06

CPC分类号： C07H19/06 ,  Y02P20/55

摘要： Disclosed are novel 2'-alkylidenepyrimidine nucleoside derivatives represented by formula [I]: ##STR1## wherein R.sup.1 is an amino gorup or a hydroxy group, R.sup.2 is a hydrogen atom, a halogen atom or a lower alkyl group, R.sup.3 is a hydrogen atom or a lower alkyl group, and R.sup.4 is a hydrogen atom or a phosphate residue, or salts thereof.These novel compounds can be produced from uridine or cytidine derivatives by alkylidenating the 2'-position in the sugar moiety thereof with Wittig's reagent.Furthermore, the compounds have remarkable antiviral activities and therefore can provide novel antiviral agents.

摘要翻译： PCT No.PCT / JP88 / 00278 Sec。 371日期1988年11月18日 102（e）1988年11月18日日期PCT提交1988年3月17日PCT公布。 出版物WO88 / 07049 日期：1988年9月22日。公开的是由式[I]表示的新颖的2'-亚烷基嘧啶核苷衍生物：其中R1是氨基酸或羟基，R2是氢原子，卤素原子或 低级烷基，R3为氢原子或低级烷基，R4为氢原子或磷酸酯基，或其盐。 这些新化合物可以由尿苷或胞苷衍生物通过用Wittig's试剂将其部分上的2'-位进行亚烷基化来制备。 此外，化合物具有显着的抗病毒活性，因此可以提供新的抗病毒剂。

公开(公告)号：US4956345A

公开(公告)日：1990-09-11

申请号：US282892

申请日：1988-12-12

申请人： Tadashi Miyasaka ,  Akira Matsuda ,  Toichi Abiru ,  Haruhiko Machida

发明人： Tadashi Miyasaka ,  Akira Matsuda ,  Toichi Abiru ,  Haruhiko Machida

IPC分类号： C07H19/167 ,  A61K31/70 ,  A61K31/7042 ,  A61K31/7052 ,  A61K31/7076 ,  A61P9/12 ,  C07H19/067 ,  C07H19/16

CPC分类号： C07H19/16

摘要： A 2-alkynyladenosine represented by general formula [I]: ##STR1## wherein n is an integer of from 2 to 15, has been found to have excellent properties as an antihypertensive agent. On the basis of this finding, the present invention has provided an antihypertensive agent comprising an antihypertensive effective amount of a compound of the above formula [I] and a pharmaceutically acceptable carrier. The present invention also discloses a novel compound 2-alkynyladenosine of formula [I] shown above wherein n is 6 to 15.

摘要翻译： 由通式[I]表示的2-炔基腺苷：其中n为2〜15的整数，已被发现具有作为抗高血压剂的优异的性质。 基于该发现，本发明提供了包含抗高血压有效量的上述式[I]的化合物和药学上可接受的载体的抗高血压药。 本发明还公开了上述式[I]的新化合物2-炔基腺苷，其中n为6至15。

公开(公告)号：US4898318A

公开(公告)日：1990-02-06

申请号：US177066

申请日：1988-04-04

申请人： Syoji Shiga ,  Akira Matsuda ,  Nobuyuki Shibata ,  Kiichi Akasaka

发明人： Syoji Shiga ,  Akira Matsuda ,  Nobuyuki Shibata ,  Kiichi Akasaka

IPC分类号： F28F19/06 ,  F28F21/08

CPC分类号： F28F21/085 ,  F28F19/06

摘要： An improved copper radiator for motor cars comprising a plurality of tubes adapted for the flow of a heat-exchanging medium therethrough, fins bonded directly with solder to said tubes to form a copper core and wherein said core is bonded with solder to at least one seat plate, the improvement in that the surface of the fins of said copper radiator has an oxidized layer of a thickness of not more than 1200 .ANG..

摘要翻译： 一种用于汽车的改进的铜辐射器，包括适于通过其中的热交换介质的流动的多个管，与焊料直接焊接到所述管的翅片以形成铜芯，并且其中所述芯与焊料接合至至少一个座 所述铜散热器的散热片的表面的厚度不超过1200安培的氧化层的改进。

公开(公告)号：US4588794A

公开(公告)日：1986-05-13

申请号：US644670

申请日：1984-08-28

申请人： Hidekuni Oda ,  Kazuhiko Murata ,  Hirokazu Kajiura ,  Akira Matsuda

发明人： Hidekuni Oda ,  Kazuhiko Murata ,  Hirokazu Kajiura ,  Akira Matsuda

IPC分类号： C08F4/76 ,  C08F210/18 ,  C08F4/68

CPC分类号： C08F210/18

摘要： A rubbery copolymer of ethylene, 1-butene and a polyene, characterized by having (A) an ethylene/1-butene mole ratio of from 86/14 to 95/5, (B) an iodine value of from 2 to 40, (C) an intrinsic viscosity [.eta.], measured in decalin at 135.degree. C., of from 0.8 to 4 dl/g, and (D) a weight average molecular weight/number average molecular weight ratio (Mw/Mn) of less than 3; and a process for the production thereof.

摘要翻译： 乙烯，1-丁烯和多烯的橡胶状共聚物，其特征在于（A）乙烯/ 1-丁烯的摩尔比为86/14〜95/5，（B）碘值为2〜40，（ C）在135℃的十氢化萘中测得的特性粘度η为0.8-4d / g，（D）重均分子量/数均分子量比（＆amp; 小于3; 及其生产方法。

公开(公告)号：US4569731A

公开(公告)日：1986-02-11

申请号：US726290

申请日：1985-04-23

申请人： Akira Matsuda ,  Akira Komoda ,  Takahisa Yoshihara ,  Kazuaki Miyachi

发明人： Akira Matsuda ,  Akira Komoda ,  Takahisa Yoshihara ,  Kazuaki Miyachi

IPC分类号： C25D3/56 ,  C25D5/26 ,  C25D7/06

CPC分类号： C25D3/565

摘要： Steel strips are electrogalvanized with a Zn-Ni alloy deposit having the desired nickel content in a consistent manner for a long time by placing separate Zn and Ni soluble anodes in a chloride plating bath comprising major proportions of ZnCl.sub.2 and NiCl.sub.2 in an Ni/(Zn+Ni) ratio between 0.08 and 0.20 and a total molar amount of Zn+Ni of from 1 to 4 moles per liter, and b mole per liter of KCl and a mole per liter of NH.sub.4 Cl as shown in FIG. 8; passing a steel strip through the bath; and introducing currents to the soluble Zn and Ni anodes in a specific ratio given by equation (2).

摘要翻译： 通过在Ni /（Zn）中包含主要比例的ZnCl 2和NiCl 2的氯化物电镀浴中放置单独的Zn和Ni可溶性阳极，将钢带用具有所需镍含量的Zn-Ni合金沉积物长时间地电镀锌 + Ni）比为0.08〜0.20，Zn + Ni的总摩尔量为1〜4摩尔/升，b摩尔/升KCl和每升NH 4 Cl摩尔数，如图3所示。 8; 将钢带穿过浴缸; 并以等式（2）给出的特定比例将电流引入可溶性Zn和Ni阳极。

公开(公告)号：US4433105A

公开(公告)日：1984-02-21

申请号：US289821

申请日：1981-08-04

申请人： Akira Matsuda ,  Tetsuo Tojyo

发明人： Akira Matsuda ,  Tetsuo Tojyo

IPC分类号： C08F8/00 ,  C08F8/20 ,  C08F8/22 ,  C08L23/28 ,  C08L27/06

CPC分类号： C08F8/22 ,  C08L27/06 ,  C08L23/28

摘要： A chlorinated rubber having a chlorine content of about 5 through about 50% by weight and a Mooney viscosity (ML.sub.1+4 at 100.degree. C.) of about 20 through about 150 is presented. This chlorinated rubber is derived from the chlorination of (i) a copolymer rubber of ethylene and 1-butene having a mol ratio of ethylene/1-butene of about 85/15 through about 95/5 or (ii) a copolymer rubber of ethylene 1-butene and 5-ethylidene-2-norbornene having a mol ratio of ethylene/1-butene of about 85/15 through about 95/5 and a content of the 5-ethylidene-2-norbornene of 20% by weight or less based on the weight of the copolymer. The incorporation of the chlorinated rubber into a polyvinyl chloride composition results in the remarkable improvement of the impact resistance and flexibility, both at a low temperature, of the polyvinyl chloride.

摘要翻译： 提供氯含量约5至约50重量％，门尼粘度（100℃时ML1 + 4）为约20至约150的氯化橡胶。 该氯化橡胶来自（i）乙烯和1-丁烯的共聚物橡胶，乙烯/ 1-丁烯的摩尔比为约85/15至约95/5，或（ii）乙烯共聚物橡胶 乙烯/ 1-丁烯的摩尔比为约85/15至约95/5的1-亚丁基和5-亚乙基-2-降冰片烯，并且5-亚乙基-2-降冰片烯的含量为20重量％以下 基于共聚物的重量。 将氯化橡胶掺入聚氯乙烯组合物中导致聚氯乙烯在低温下的耐冲击性和柔韧性显着提高。

公开(公告)号：US4327081A

公开(公告)日：1982-04-27

申请号：US88527

申请日：1979-10-26

申请人： Akira Matsuda ,  Osamu Yoshioka ,  Katsutoshi Takahashi ,  Kooichi Yoshida ,  Hiroshi Ninomiya

发明人： Akira Matsuda ,  Osamu Yoshioka ,  Katsutoshi Takahashi ,  Kooichi Yoshida ,  Hiroshi Ninomiya

IPC分类号： A61K31/505 ,  A61K38/14 ,  A61K47/32 ,  A61K31/78

CPC分类号： A61K31/505 ,  A61K38/14 ,  A61K47/32 ,  Y10S514/804

摘要： This invention relates to a method for selectively enhancing absorption of 5-fluorouracil, bleomycins or bleomycin derivatives into the gastrointestinal tumor site by orally administering such substance together with an alkali metal salt of polyacrylic acid, and an orally administrable antitumor composition used for such method.

摘要翻译： 本发明涉及通过将这种物质与聚丙烯酸的碱金属盐一起口服给药，以及用于该方法的口服给药的抗肿瘤剂组合物，选择性地增强5-氟尿嘧啶，博来霉素或博来霉素衍生物对胃肠道肿瘤部位的吸收的方法。

公开(公告)号：US4275377A

公开(公告)日：1981-06-23

申请号：US49830

申请日：1979-06-18

申请人： Akira Matsuda ,  Norio Goshima ,  Shigeo Yasuda ,  Motoaki Iwasaki ,  Hiroshi Nishino

发明人： Akira Matsuda ,  Norio Goshima ,  Shigeo Yasuda ,  Motoaki Iwasaki ,  Hiroshi Nishino

IPC分类号： G08C19/00 ,  B60C23/02 ,  B60C23/04 ,  G08B21/00

CPC分类号： B60C23/0428

摘要： An alarm device for signalling a reduction of pneumatic vehicle tire pressure comprises an oscillator 6 having an oscillation coil secured to a chassis of a vehicle; and a resonator 1 secured to the peripheral portion of a wheel having a tire adjacent to the oscillation coil and consisting of a pressure switch 4 for sensing an abnormal tire pressure change and a resonance coil and a capacitor 5 tuned to an electromagnetic wave radiated from the oscillation coil. A signal processing device contains a means for sensing a change in an oscillation condition generated in the oscillator due to a resonant condition of the resonator switched on and off in accordance with abnormal internal tire pressure and for processing a signal from the sensing means; and an alarm for generating a warning signal in accordance with the output of the signal processing device. The latter comprises a signal input section 21 having a desired number of input terminals, a signal processing section 22 having an arithmetic circuit connected to the signal input section, a resettable latch circuit 30,32, and an alarm section 23 operated by the output of the latch circuit whereby an alarm signal is not generated at normal internal pressure and during stops of the vehicle.

摘要翻译： 用于指示气动车辆轮胎压力降低的报警装置包括具有固定到车辆的底盘的振荡线圈的振荡器6; 以及固定到具有与振荡线圈相邻的轮胎的轮的周边部分的谐振器1，其包括用于感测异常轮胎压力变化的压力开关4和谐振线圈，以及调谐到从所述振荡线圈辐射的电磁波的电容器5 振荡线圈 信号处理装置包括用于感测由于根据异常的内部轮胎压力而导通和关断谐振器的共振状态并且用于处理来自感测装置的信号的振荡器中产生的振荡条件的变化的装置; 以及根据信号处理装置的输出产生警告信号的警报。 后者包括具有期望数量的输入端子的信号输入部分21，具有连接到信号输入部分的运算电路的信号处理部分22，可复位锁存电路30,32和由输出的操作的报警部分23 闩锁电路，由此在正常内部压力下和在车辆停止期间不产生报警信号。