公开(公告)号：US08293714B2

公开(公告)日：2012-10-23

申请号：US12432528

申请日：2009-04-29

Applicant: Venkata Ramana Doppalapudi ,  Jing-Yu Lai ,  Bin Liu ,  Dingguo Liu ,  Joel Desharnais ,  Abhijit Suresh Bhat ,  Yanwen Fu ,  Bryan Douglas Oates ,  Gang Chen ,  Curt William Bradshaw

Inventor： Venkata Ramana Doppalapudi ,  Jing-Yu Lai ,  Bin Liu ,  Dingguo Liu ,  Joel Desharnais ,  Abhijit Suresh Bhat ,  Yanwen Fu ,  Bryan Douglas Oates ,  Gang Chen ,  Curt William Bradshaw

IPC: A61K38/16

CPC classification number: A61K47/48215 ,  A61K47/48246 ,  A61K47/48415 ,  A61K47/48507 ,  A61K47/60 ,  A61K47/64 ,  A61K47/6811 ,  A61K47/6835 ,  C07K14/71

Abstract: The present invention provides VEGF binding peptides. In addition, the invention provides VEGF peptides conjugated to antibodies alone and in conjunction with other anti-angiogenic molecules. Various uses of the peptides and compounds are provided, including methods to treat disorders associated with abnormal angiogenesis.

Abstract translation: 本发明提供VEGF结合肽。 此外，本发明提供了与单独的抗体和其它抗血管生成分子结合的VEGF肽。 提供肽和化合物的各种用途，包括治疗与异常血管发生相关的疾病的方法。

公开(公告)号：US20120263030A1

公开(公告)日：2012-10-18

申请号：US13532410

申请日：2012-06-25

Applicant: Mark Hahm ,  Wei Luo ,  Thirunathan Sutharsan ,  Andrew du Preez ,  Bin Liu ,  Jun Wu ,  Severine Catreux-Erceg ,  Shuangquan Wang

Inventor： Mark Hahm ,  Wei Luo ,  Thirunathan Sutharsan ,  Andrew du Preez ,  Bin Liu ,  Jun Wu ,  Severine Catreux-Erceg ,  Shuangquan Wang

IPC: H04W88/00

CPC classification number: H04B1/71075 ,  H04B1/7115 ,  H04B1/712 ,  H04B2201/70702

Abstract: Aspects of a method and system for a programmable interference suppression module may include receiving a communication signal comprising one or more desired signal, and one or more undesired signals. The communication signal may be utilized to generate estimated channel state information. The estimated channel state information may be formatted for use in interference suppression. A reduced interference signal may be generated from a delayed version of said communications signal and the estimated channel state information, wherein the one or more undesired signals may be attenuated. The reduced interference signal may be formatted for post-processing. The desired signals may comprise WCDMA and/or HSDPA signals, and the undesired signals may be inter-cell and/or intra-cell interference. Further processing may comprise HSDPA processing and/or RAKE finger processing. The communication signal may be a Universal Mobile Telecommunication System (UMTS) compliant signal.

Abstract translation: 用于可编程干扰抑制模块的方法和系统的方面可以包括接收包括一个或多个期望信号的通信信号以及一个或多个不需要的信号。 通信信号可用于产生估计的信道状态信息。 估计的信道状态信息可以被格式化以用于干扰抑制。 可以从所述通信信号的延迟版本和所估计的信道状态信息产生减小的干扰信号，其中所述一个或多个不需要的信号可以被衰减。 减小的干扰信号可以被格式化用于后处理。 期望的信号可以包括WCDMA和/或HSDPA信号，并且不期望的信号可以是小区间和/或小区内干扰。 进一步的处理可以包括HSDPA处理和/或RAKE手指处理。 通信信号可以是符合通用移动通信系统（UMTS）的信号。

公开(公告)号：US20120252986A1

公开(公告)日：2012-10-04

申请号：US13378989

申请日：2010-06-25

Applicant: Bin Liu ,  Chun Wang ,  Ruoyu Zhan ,  Glenn P. Bartholomew ,  Janice W. Hong ,  Jean M. Wheeler ,  Brent S. Gaylord

Inventor： Bin Liu ,  Chun Wang ,  Ruoyu Zhan ,  Glenn P. Bartholomew ,  Janice W. Hong ,  Jean M. Wheeler ,  Brent S. Gaylord

IPC: C08G65/00

CPC classification number: C08G61/02 ,  C08G2261/3142 ,  C08G2261/3422 ,  C08G2261/5222

Abstract: The devices and method are provided for detecting labeled and label-free analytes, such as nucleic acids and proteins, employing conjugated cationic, anionic and neutral polymers. The analytes can be immobilized on a solid support material. The solid support material can be disposed in the pre-fabricated patterns on a substrate. The chemical structures of the polymers employed by the various embodiments of the present invention are described herein.

Abstract translation: 提供的装置和方法用于检测标记和无标记分析物，如核酸和蛋白质，使用共轭阳离子，阴离子和中性聚合物。 分析物可以固定在固体支持材料上。 固体支撑材料可以以衬底上的预制图案设置。 本文描述了由本发明的各种实施方案采用的聚合物的化学结构。

公开(公告)号：US08248192B2

公开(公告)日：2012-08-21

申请号：US12685132

申请日：2010-01-11

Applicant: Juhai Hu ,  Yulin Zhang ,  Bin Liu ,  Jianning Jiang

Inventor： Juhai Hu ,  Yulin Zhang ,  Bin Liu ,  Jianning Jiang

IPC: H01H75/00 ,  H01H73/12 ,  H01H73/00 ,  H01H83/06 ,  H02H3/00 ,  H02H9/08

CPC classification number: H01H71/322 ,  H01H71/123 ,  H01H83/02

Abstract: A pulse activated magnetic trip/reset mechanism for a ground fault circuit interrupter, comprising: (i) a body, (ii) a ferrite core, (iii) a plunger, (iv) a ferrite surrounding, (v) a permanent magnet, (vi) a trip/reset coil, (vii) a reset spring positioned between a plunger block and the body, (viii) a first fixed contact holder having a first fixed contact point, and (ix) a first movable contact holder having a first movable contact point, wherein the first movable contact holder is attached to the body of the plunger such that when the plunger is in its first position (trip position), the first movable contact point is not in contact with the first fixed contact point, and when the plunger is in its second position (reset position), the first movable contact point is in contact with the first fixed contact point.

Abstract translation: 一种用于接地故障电路断续器的脉冲激励磁跳闸/复位机构，包括：（i）主体，（ii）铁氧体磁芯，（iii）柱塞，（iv）围绕（v）永磁体的铁氧体， （vi）跳闸/复位线圈，（vii）定位在柱塞块和主体之间的复位弹簧，（viii）具有第一固定接触点的第一固定触点保持器，和（ix）第一可动触点保持器， 第一可动接触点，其中第一可动触头保持器附接到柱塞的主体，使得当柱塞处于其第一位置（跳闸位置）时，第一可动触点不与第一固定触点接触， 并且当柱塞处于其第二位置（复位位置）时，第一可动触点与第一固定触点接触。

公开(公告)号：US20110136541A1

公开(公告)日：2011-06-09

申请号：US13026234

申请日：2011-02-12

Applicant: Eric Chang ,  David Dehghan ,  Stanley Sun ,  Bin Liu

Inventor： Eric Chang ,  David Dehghan ,  Stanley Sun ,  Bin Liu

IPC: H04W88/02

CPC classification number: H04M1/72527

Abstract: A universal smart interface and peripheral management system for portable devices such as mobile phones. The smart system includes a connector interface that connects peripherals to a phone and/or personal digital assistant (PDA), through the smart system. The smart system includes a cradle for receiving a cell phone and interfacing the phone to external systems such as peripherals, networks and other systems through a USB hub and other suitable connector interfaces. The peripheral devices to which the smart system can interface include, but are not limited to, large displays (e.g., television), external monitors, input devices such as mice and keyboards, external storage devices, and networks (wired and/or wireless). The smart system also facilitates connectivity to large display systems such as TVs, computer displays and monitors.

Abstract translation: 通用智能接口和便携式设备（如手机）的外设管理系统。 智能系统包括通过智能系统将外围设备连接到电话和/或个人数字助理（PDA）的连接器接口。 该智能系统包括用于接收蜂窝电话并通过USB集线器和其他合适的连接器接口将电话与诸如外围设备，网络和其他系统的外部系统接口的支架。 智能系统可以接口的外围设备包括但不限于大型显示​​器（例如电视机），外部监视器，诸如鼠标和键盘的输入设备，外部存储设备和网络（有线和/或无线） 。 智能系统还有助于连接大型显示系统，如电视机，电脑显示器和显示器。

公开(公告)号：US20100239532A1

公开(公告)日：2010-09-23

申请号：US12676511

申请日：2007-09-04

Applicant: Weidong Zhou ,  Qingjing Xiao ,  Li Sun ,  Tlebing Wang ,  Bin Liu ,  Song Lin ,  Min Liu ,  Fenghong Yin ,  Lu Zhuang ,  Lifang Lei

Inventor： Weidong Zhou ,  Qingjing Xiao ,  Li Sun ,  Tlebing Wang ,  Bin Liu ,  Song Lin ,  Min Liu ,  Fenghong Yin ,  Lu Zhuang ,  Lifang Lei

IPC: A61K38/21 ,  C07K17/06 ,  A61P29/00 ,  A61P35/00 ,  A61P31/20 ,  A61P31/14 ,  A61P19/02 ,  A61P11/06 ,  A61P11/00

CPC classification number: C07K14/56 ,  A61K38/00 ,  A61K47/60 ,  Y02A50/473

Abstract: The present invention relates to interferon (IFN)-α2a modified at a specific Lys residue with Y-shaped branched polyethylene glycol (PEG) derivative and the preparation thereof, as well as the use of the prepared IFN-α2a modified by PEG at a single amino acid residue in medicines.

Abstract translation: 本发明涉及在具有Y型支链聚乙二醇（PEG）衍生物的特定Lys残基上修饰的干扰素（IFN）-α2a及其制备方法，以及在单次使用由PEG修饰的制备的IFN-α2a 药物中的氨基酸残基。

公开(公告)号：US20100016373A1

公开(公告)日：2010-01-21

申请号：US12502252

申请日：2009-07-14

Applicant: Albert Khilevich ,  Bin Liu ,  Daniel Ray Mayhugh ,  Jeffrey Michael Schkeryantz ,  Deyi Zhang

Inventor： Albert Khilevich ,  Bin Liu ,  Daniel Ray Mayhugh ,  Jeffrey Michael Schkeryantz ,  Deyi Zhang

IPC: A61K31/4439 ,  C07D233/64 ,  C07D401/12 ,  A61K31/4164

CPC classification number: C07D233/92

Abstract: The present invention provides certain imidazole carboxamide derivatives, pharmaceutical compositions thereof, methods of using the same and processes for preparing the same.

Abstract translation: 本发明提供某些咪唑羧酰胺衍生物，其药物组合物，其使用方法及其制备方法。

公开(公告)号：US07545857B2

公开(公告)日：2009-06-09

申请号：US10884406

申请日：2004-07-01

Applicant: Bin Liu

Inventor： Bin Liu

IPC: H04B1/38 ,  H04B1/10

CPC classification number: H04L27/22 ,  H03D3/009

Abstract: A communications receiver architecture characterized by a relatively low intermediate frequency (IF) and a polyphase filter. The receiver includes an input amplifier coupled to a carrier signal. Respective I and Q demodulators are coupled to the output of the input amplifier. A quadrature local oscillator (LO) generator provides respective LO_I and LO_Q inputs to the I demodulator and LO_Q inputs to the I demodulator and to the Q demodulator. The quadrature LO generator is driven by a phase-locked LO, and the LO frequency is such that an IF of, in one embodiment, approximately 1 MHz results. The I demodulator and Q demodulator outputs are applied through respective AID converters to a polyphase filter. The polyphase filter outputs are then processed by a digital I/Q demodulator. Although a low IF is not generally understood to promote the image rejection performance of a receiver, substantial image rejection is afforded by the polyphase filter, thereby enabling the receiver to be realized almost entirely as a monolithic integrated semiconductor device.

Abstract translation: 一种以相对低的中频（IF）和多相滤波器为特征的通信接收机架构。 接收机包括耦合到载波信号的输入放大器。 相应的I和Q解调器耦合到输入放大器的输出端。 正交本地振荡器（LO）发生器向I解调器提供相应的LO_I和LO_Q输入，并向I解调器和Q解调器提供LO_Q输入。 正交LO发生器由锁相LO驱动，LO频率使得在一个实施例中，IF的IF约为1MHz。 I解调器和Q解调器输出通过相应的AID转换器应用于多相滤波器。 多相滤波器输出由数字I / Q解调器处理。 虽然通常不理解低IF以促进接收机的镜像抑制性能，但是由多相滤波器提供了大量的图像抑制，从而使接收机几乎完全可以实现为单片集成半导体器件。

公开(公告)号：US20080175863A1

公开(公告)日：2008-07-24

申请号：US11780627

申请日：2007-07-20

Applicant: Hong Jin ,  Bin Liu

Inventor： Hong Jin ,  Bin Liu

IPC: A61K39/145 ,  C12N15/01 ,  C12N7/00 ,  A61P31/20

CPC classification number: C12N7/00 ,  A61K39/12 ,  A61K39/145 ,  C07K14/005 ,  C12N2760/16121 ,  C12N2760/16122 ,  C12N2760/16134

Abstract: In certain aspects, the present invention provides methods for increasing the replication capacity of influenza viruses in hens' eggs and/or cell culture, recombinant and/or reassortant influenza viruses with increased replication capacity, and immunogenic and vaccine compositions comprising such recombinant and/or reassortant influenza viruses. In other aspects, the invention further provides nucleic acids encoding influenza genes associated with increased replication capacity, expression vectors comprising the nucleic acids of the invention, methods for making influenza viruses with increased replication capacity, and kits useful for practice of the methods.

Abstract translation: 在某些方面，本发明提供了增加在具有增加的复制能力的母鸡卵和/或细胞培养物，重组和/或重配流感病毒中的流感病毒的复制能力的方法，以及包含这种重组和/或 重配流感病毒。 在其它方面，本发明还提供编码与增加的复制能力相关的流感基因的核酸，包含本发明的核酸的表达载体，具有增加的复制能力的制备流感病毒的方法，以及可用于实施该方法的试剂盒。

公开(公告)号：US07366532B2

公开(公告)日：2008-04-29

申请号：US10682772

申请日：2003-10-09

Applicant: Charbel Khawand ,  Bin Liu ,  Jianping W. Miller

Inventor： Charbel Khawand ,  Bin Liu ,  Jianping W. Miller

IPC: H04B7/01

CPC classification number: H04B7/269 ,  H04W56/002 ,  H04W56/0035 ,  H04W92/18

Abstract: A method of communicating with a transceiver (120). In one arrangement, the method of communicating with the transceiver can be performed in a systemless group environment. Synchronization information (150) can be received from a mobile transceiver (110) and used to synchronize to the mobile transceiver. The synchronization information can include a timing offset and a frequency offset. Synchronization can be maintained until a predetermined condition is met, for example, a predetermined amount of group inactivity.

Abstract translation: 一种与收发器（120）进行通信的方法。 在一种布置中，可以在无系统的组环境中执行与收发器通信的方法。 可以从移动收发机（110）接收同步信息（150）并用于与移动收发信机同步。 同步信息可以包括定时偏移和频率偏移。 可以保持同步，直到满足预定条件，例如，预定量的组不活动。