公开(公告)号：US20090324124A1

公开(公告)日：2009-12-31

申请号：US12215965

申请日：2008-06-30

Applicant: John G. Milanski ,  Joan Stagaman Goddard ,  Kenneth Stuart Shouldice ,  Hong Li

Inventor： John G. Milanski ,  Joan Stagaman Goddard ,  Kenneth Stuart Shouldice ,  Hong Li

IPC: G06K9/40

CPC classification number: H04N1/6027 ,  H04N1/6002 ,  H04N1/6013

Abstract: A color adjustment interface includes an original image thumbnail representing a version of an image prior to modification, a current image thumbnail representing a version of an image after a modification and a color polygon including a multitude of variation image thumbnails each representing a color variation. Each selection of a variation image thumbnail modifies the current image thumbnail in an adjustment towards a color represented by the selected variation image.

Abstract translation: 颜色调整界面包括表示修改前的图像的版本的原始图像缩略图，表示修改后的图像的版本的当前图像缩略图，以及包含各自表示颜色变化的多个变体图像缩略图的颜色多边形。 变化图像缩略图的每个选择将调整中的当前图像缩略图修改为由所选择的变化图像表示的颜色。

公开(公告)号：US20090174902A1

公开(公告)日：2009-07-09

申请号：US12350861

申请日：2009-01-08

Applicant: Hong Li ,  Joseph S. Czyszczewski ,  James T. Smith, II

Inventor： Hong Li ,  Joseph S. Czyszczewski ,  James T. Smith, II

IPC: G06F3/12 ,  H04N1/46

CPC classification number: H04N1/6033

Abstract: Methods, systems, and media to enhance image processing for a color reprographic system are disclosed. Embodiments of the invention may calibrate a component like scanner and/or printer in response to user input and/or coupling the component to the reprographic system. More specifically, embodiments may generate correction parameters that describe differences in color values between an image scanned by a scanner or an image printed by the printer by comparing the outputs to known characteristics like color values for the image. Some embodiments comprise a graphical user interface (GUI) to communicate with the user, allowing the user to select user preferences to change, for example, the brightness of an image being copied. Further embodiments incorporate network and phone system interfaces to communicate with remote components as well as to receive input from and/or output to other systems via email, facsimile, etc.

Abstract translation: 公开了用于增强彩色再现系统的图像处理的方法，系统和媒体。 本发明的实施例可以响应于用户输入和/或将组件耦合到复制系统来校准诸如扫描仪和/或打印机的组件。 更具体地，实施例可以产生校正参数，其描述由扫描仪扫描的图像或由打印机打印的图像之间的颜色值的差异，通过将输出与已知特征（例如图像的颜色值）进行比较。 一些实施例包括与用户通信的图形用户界面（GUI），允许用户选择用户偏好以改变例如被复制的图像的亮度。 其他实施例将网络和电话系统接口与远程组件进行通信，以及通过电子邮件，传真等从其他系统接收和/或输出输入。

公开(公告)号：US20080119476A1

公开(公告)日：2008-05-22

申请号：US11631821

申请日：2005-07-01

Applicant: Amjad Ali ,  Joann M. Napolitano ,  Qiaolin Deng ,  Zhijian Lu ,  Peter J. Sinclair ,  Gayle E. Taylor ,  Christopher F. Thompson ,  Nazia Quraishi ,  Cameron J. Smith ,  Julianne A. Hunt ,  Adrian A. Dowst ,  Yi-Heng Chen ,  Hong Li

Inventor： Amjad Ali ,  Joann M. Napolitano ,  Qiaolin Deng ,  Zhijian Lu ,  Peter J. Sinclair ,  Gayle E. Taylor ,  Christopher F. Thompson ,  Nazia Quraishi ,  Cameron J. Smith ,  Julianne A. Hunt ,  Adrian A. Dowst ,  Yi-Heng Chen ,  Hong Li

IPC: A61K31/422 ,  A61K31/40 ,  A61K31/4166 ,  A61K31/427 ,  A61K31/4439 ,  A61K31/501 ,  A61P9/10 ,  C07D233/32 ,  C07D263/20 ,  C07D417/10 ,  C07D417/04 ,  C07D413/10 ,  C07D413/04 ,  C07D401/04 ,  C07D285/10 ,  C07D233/44 ,  C07D207/24 ,  A61K31/506 ,  A61K31/497 ,  A61K31/433 ,  A61K31/4168 ,  A61K31/421

CPC classification number: C07F7/10 ,  A61K31/4015 ,  A61K31/4166 ,  A61K31/4168 ,  A61K31/421 ,  A61K31/422 ,  A61K31/427 ,  A61K31/433 ,  A61K31/4439 ,  A61K31/497 ,  A61K31/501 ,  A61K31/506 ,  A61K45/06 ,  C07D207/26 ,  C07D207/27 ,  C07D233/32 ,  C07D233/38 ,  C07D233/50 ,  C07D233/52 ,  C07D263/04 ,  C07D263/20 ,  C07D263/22 ,  C07D263/24 ,  C07D263/26 ,  C07D285/06 ,  C07D285/10 ,  C07D401/04 ,  C07D413/04 ,  C07D413/06 ,  C07D413/10 ,  C07D417/04 ,  C07D417/10

Abstract: Compounds having the structures of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis: In the compounds of Formula I, B or R2 is a phenyl group which has an ortho aryl, heterocyclic, benzoheterocyclic or benzocycloalkyl substituent, and one other position on the 5-membered ring has an aromatic, heterocyclic, cycloalkyl, benzoheterocyclic or benzocycloalkyl substituent connected directly to the ring or attached to the ring through a —CH2—.

Abstract translation: 具有式I结构的化合物，包括化合物的药学上可接受的盐，是CETP抑制剂，可用于升高HDL-胆固醇，降低LDL-胆固醇，以及用于治疗或预防动脉粥样硬化。在式I化合物中，B或 R 2是具有邻芳基，杂环，苯并杂环或苯并环烷基取代基的苯基，并且在5元环上的另一个位置具有直接连接的芳族，杂环，环烷基，苯并杂环或苯并环烷基取代基 通过-CH 2 - 2连接到环上或连接到环上。

公开(公告)号：US07334103B2

公开(公告)日：2008-02-19

申请号：US10538211

申请日：2003-12-08

Applicant: Johannes H. M. Korst ,  Hong Li ,  Robert Jochemsen ,  Nicolaas Lambert ,  Gerardus W. T. Van Der Heijden

Inventor： Johannes H. M. Korst ,  Hong Li ,  Robert Jochemsen ,  Nicolaas Lambert ,  Gerardus W. T. Van Der Heijden

IPC: G06F12/00

CPC classification number: H04N21/2393 ,  G06F3/0613 ,  G06F3/0656 ,  G06F3/0659 ,  G06F3/0676 ,  H04N21/2326 ,  H04N21/23406 ,  H04N21/44004 ,  H04N21/47202

Abstract: A method for breathing of scheduling algorithms for a storage device (110). The method including: (a) computing a worst-case duration of a breathing cycle (P) for the storage device (110); (b) starting a breathing cycle; (c) determining if one of the following becomes true before the end of P: (i) a number of real-time requests is at least a predetermined threshold based on a number of data streams and performance parameters of the storage device; and (ii) a number of pending requests for any single stream becomes more than one; (d) if at least one of (i) and (ii) remain true during the duration of P, starting a subsequent breathing cycle after completion of the breathing cycle; and (e) if both of (i) and (ii) are not true during the duration of P, waiting P time units from the start of the breathing cycle before starting the subsequent breathing cycle.

Abstract translation: 一种用于呼叫用于存储设备（110）的调度算法的方法。 该方法包括：（a）计算存储装置（110）的呼吸周期（P）的最坏情况持续时间; （b）开始呼吸循环; （c）在P结束之前确定以下之一是否成立：（i）基于数据流的数量和存储设备的性能参数，多个实时请求至少为预定阈值; 和（ii）一些待处理的任何单个流的请求变得不止一个; （d）如果（i）和（ii）中的至少一个在P期间保持为真，则在呼吸循环完成之后开始随后的呼吸循环; 和（e）如果（P）期间（i）和（ii）两者都不为真，则在开始随后的呼吸循环之前从呼吸循环开始等待P时间单位。

公开(公告)号：US20080040368A1

公开(公告)日：2008-02-14

申请号：US11463735

申请日：2006-08-10

Applicant: Hong Li ,  Christopher John Stakutis

Inventor： Hong Li ,  Christopher John Stakutis

IPC: G06F7/00

CPC classification number: H04L67/06 ,  H04L67/1095

Abstract: Provided are techniques for transferring data. It is determined whether an indicators map is to be associated with a source file that is being opened, wherein the indicators map indicates which source blocks of the source file have been updated since last being transferred to a target file. In response to determining that an indicators map is to be associated with the source file, it is determined whether the indicators map exists. In response to determining that the indicators map exists, it is determined whether the indicators map is to be trusted based on a last modified time and a last source file size stored in the indicators map and the source file. In response to determining that the indicators map is to be trusted, the indicators map is initialized. Then, in response to receiving a write for the source file, the indicators map is updated to indicate which portion of the source file has been modified.

Abstract translation: 提供了传输数据的技术。 确定指示符映射是否与要打开的源文件相关联，其中指示符映射指示自上次被传送到目标文件以来，源文件的哪些源块已被更新。 响应于确定指示符映射与源文件相关联，确定指示符映射是否存在。 响应于确定指示符映射存在，基于存储在指示符映射和源文件中的最后修改时间和最后一个源文件大小来确定指示符映射是否被信任。 响应于确定指示符映射是可信任的，指示器映射被初始化。 然后，响应于接收到源文件的写入，指示符映射被更新以指示源文件的哪个部分已被修改。

公开(公告)号：USRE40049E1

公开(公告)日：2008-02-12

申请号：US11412250

申请日：2006-04-26

Applicant: Hong Li

Inventor： Hong Li

IPC: F25D3/00 ,  F25B9/00 ,  F25B7/00

CPC classification number: F25D3/10 ,  A61B18/02 ,  A61B2018/0212 ,  A61B2018/0262

Abstract: A method and apparatus for using a secondary refrigerant to precool and liquefy a primary refrigerant, then vaporizing and expanding the primary refrigerant to cool a cold tip of a cryosurgical instrument for ablation of biological tissue, such as cardiovascular tissue, in particular endocardiac tissue and tissue inside a cardiac blood vessel. The secondary refrigerant has a critical temperature above the critical temperature of the primary refrigerant, and a cooling temperature below the critical temperature of the primary refrigerant, thereby facilitating the use of the precooling step to provide liquid primary refrigerant in an operating room environment in which the primary refrigerant could not otherwise be provided in the liquid phase.

Abstract translation: 一种用于使用二次制冷剂来预冷和液化一级制冷剂的方法和装置，然后蒸发和膨胀一级制冷剂以冷却冷冻手术器械的冷端以消除生物组织，例如心血管组织，特别是心内膜组织和组织 在心脏血管内。 次级制冷剂具有高于初级制冷剂的临界温度的临界温度，以及低于初级制冷剂的临界温度的冷却温度，从而有助于使用预冷却步骤在操作室环境中提供液体一级制冷剂，其中 初级制冷剂不能在液相中提供。

公开(公告)号：US20070150440A1

公开(公告)日：2007-06-28

申请号：US10595751

申请日：2004-11-25

Applicant: Johannes Korst ,  Robert Jochemsen ,  Hong Li

Inventor： Johannes Korst ,  Robert Jochemsen ,  Hong Li

IPC: G06F17/30

CPC classification number: G11B27/005 ,  G11B2220/216 ,  G11B2220/257 ,  H04N5/775 ,  H04N5/781 ,  H04N5/783 ,  H04N9/8042

Abstract: Non-contiguous storage of data objects seriously hampers retrieval speed of said data objects (202). Furthermore, when multiple data objects are retrieved of which some are fragmented, retrieval time of all data objects gets less predictable. Therefore, it is desirable to retrieve non-fragmented data objects only. For certain cases, this is possible, as not necessarily one specific data object has to be retrieved. In such cases, retrieval of a similar data object, render of the same type, is sufficient. To this, the invention provides among others a method and circuit (124) for retrieval of data. The invention is especially suitable for retrieving audiovisual data for trickplay. When a first frame selected for rendering is stored fragmented, a second, not fragmented frame is selected and retrieved instead of the first frame.

Abstract translation: 数据对象的非连续存储严重妨碍所述数据对象（202）的检索速度。 此外，当检索到多个数据对象中哪些数据对象被分段时，所有数据对象的检索时间变得不可预测。 因此，仅仅检索非碎片化数据对象是理想的。 对于某些情况，这是可能的，因为不一定必须检索一个特定的数据对象。 在这种情况下，类似数据对象的检索是相同类型的渲染就足够了。 为此，本发明提供了用于检索数据的方法和电路（124）。 本发明特别适用于检索用于特技播放的视听数据。 当选择用于呈现的第一帧被分段存储时，选择和检索第二个不分段的帧而不是第一帧。

公开(公告)号：US20070134332A1

公开(公告)日：2007-06-14

申请号：US11603660

申请日：2006-11-21

Applicant: William Turnell ,  Geoffrey Landis ,  Zaza Gomurashvili ,  Hong Li ,  Kristin DeFife ,  Vassil Vassilev ,  Yumin Yuan

Inventor： William Turnell ,  Geoffrey Landis ,  Zaza Gomurashvili ,  Hong Li ,  Kristin DeFife ,  Vassil Vassilev ,  Yumin Yuan

IPC: A61K48/00 ,  A61K38/28 ,  C08F20/00 ,  A61K9/14

CPC classification number: A61K9/167 ,  A61K9/1075 ,  A61K9/5146 ,  A61K38/28 ,  A61K47/59 ,  A61K47/593 ,  A61K47/595 ,  C08L77/12

Abstract: The present invention provides biodegradable polymer particle delivery compositions for delivery of macromolecular biologics, for example in crystal form, based on polymers, such as polyester amide (PEA), polyester urethane (PEUR), and polyester urea (PEU) polymers, which contain amino acids in the polymer. The polymer particle delivery compositions can be formulated either as a liquid dispersion or a lyophilized powder of polymer particles containing bound water molecules with the macromolecular biologics, for example insulin, dispersed in the particles. Bioactive agents, such as drugs, polypeptides, and polynucleotides can also be delivered by using particles sized for local, oral, mucosal or circulatory delivery. Methods of delivering a macromolecular biologic with substantial native activity to a subject, for example orally, are also included.

Abstract translation: 本发明提供了生物可降解的聚合物颗粒递送组合物，其用于输送大分子生物制剂，例如以晶体形式，基于聚合物，例如含有氨基的聚酯酰胺（PEA），聚酯聚氨酯（PEUR）和聚酯尿素（PEU）聚合物 聚合物中的酸。 聚合物颗粒递送组合物可以配制成分散在颗粒中的液体分散体或含有结合水分子的聚合物颗粒与大分子生物制剂例如胰岛素的冻干粉末。 生物活性剂，例如药物，多肽和多核苷酸也可以通过使用尺寸适于局部，口服，粘膜或循环递送的颗粒递送。 还可以包括向受试者例如口服递送具有大量天然活性的大分子生物学方法。

公开(公告)号：US20070077272A1

公开(公告)日：2007-04-05

申请号：US11525491

申请日：2006-09-21

Applicant: Hong Li ,  William Turnell ,  Yumin Yuan ,  Geoffrey Landis ,  Ryan Knoy

Inventor： Hong Li ,  William Turnell ,  Yumin Yuan ,  Geoffrey Landis ,  Ryan Knoy

IPC: A61K48/00 ,  A61K39/395 ,  C08F20/00 ,  A61F2/02

CPC classification number: C08G69/44 ,  A61K9/0024 ,  A61K47/34 ,  A61L27/34 ,  A61L31/10 ,  C08L77/12 ,  C08L2666/02

Abstract: The present invention provides an implantable solid polymer delivery composition that can be formulated to release a bioactive agent to an interior body site at a controlled rate over an extended period of time by adjusting the various components of the composition. The controlled delivery of the composition avoids an initial drug spike, resulting in a smooth delivery profile over time. Polymer layers in the composition can be porous and are both biodegradable in water and body enzymes and biocompatible. Methods of making the implantable solid polymer compositions and methods of delivering a bioactive agent at a controlled rate to an interior body site are also provided.

Abstract translation: 本发明提供了一种可植入的固体聚合物递送组合物，其可通过调节组合物的各种成分而配制成在长时间内以受控的速率将生物活性剂释放到内部身体部位。 组合物的受控输送避免了初始药物尖峰，导致随着时间的顺利递送。 组合物中的聚合物层可以是多孔的，并且在水和身体酶中都是可生物降解的并且是生物相容的。 还提供了制造可植入固体聚合物组合物的方法和将受控速率递送至内部身体部位的生物活性剂的方法。

公开(公告)号：US20070074163A1

公开(公告)日：2007-03-29

申请号：US10577099

申请日：2004-10-18

Applicant: Jozef Van Gassel ,  Hong Li ,  Adrianus Johannes Denissen ,  Adolf Proidl ,  Gerhardus Mekenkamp

Inventor： Jozef Van Gassel ,  Hong Li ,  Adrianus Johannes Denissen ,  Adolf Proidl ,  Gerhardus Mekenkamp

IPC: G06F9/44

CPC classification number: H04L41/0886 ,  H04L41/0806 ,  H04L41/0809 ,  H04L41/12

Abstract: A method is provided for enabling to establish a connection between multiple UpnP-compliant resources, wherein each of the resources has a respective ConnectionManager service. The method comprises configuring the respective ConnectionManager services so to enable a UpnP Control Point to use the respective services for negotiating the connection between the respective resources to be established at a time determined in advance.

Abstract translation: 提供了一种能够建立多个UpnP兼容资源之间的连接的方法，其中每个资源具有相应的ConnectionManager服务。 该方法包括配置相应的ConnectionManager服务，以使UpnP控制点能够使用相应的服务来协商在预先确定的时间内要建立的各个资源之间的连接。