公开(公告)号：US20170340790A1

公开(公告)日：2017-11-30

申请号：US15676475

申请日：2017-08-14

申请人： Berlin Heart GmbH

发明人： Constantin Wiesener ,  Dominik Karch

IPC分类号： A61M1/10 ,  A61M1/00 ,  A61M1/12

CPC分类号： A61M1/1086 ,  A61M1/0023 ,  A61M1/10 ,  A61M1/101 ,  A61M1/1015 ,  A61M1/1017 ,  A61M1/1029 ,  A61M1/1031 ,  A61M1/1087 ,  A61M1/1096 ,  A61M1/1098 ,  A61M1/122 ,  A61M2230/005 ,  A61M2230/63

摘要： A method may be provided for the operation of a pump device, which comprises at least one pump as well as a suction element which is connected to the at least one pump and which has a suction opening positioned in a cavity of a body of a patient that sucks a fluid by way of producing a reduced pressure in the suction element, wherein an acceleration is measured and monitored during the operation of the pump device, wherein the reduced pressure in the suction element is reduced at least for a limited reaction time period, given the occurrence of an acceleration variable which lies above a fixed threshold valve. A correspondingly configured pump device may be provided.

公开(公告)号：US20170340788A1

公开(公告)日：2017-11-30

申请号：US15619335

申请日：2017-06-09

申请人： Queen Mary University of London

发明人： Theodosios Korakianitis ,  Martin T. Rothman

IPC分类号： A61M1/10 ,  A61M1/12 ,  A61F2/06

CPC分类号： A61M1/1046 ,  A61F2/06 ,  A61M1/1005 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1031 ,  A61M1/107 ,  A61M1/1086 ,  A61M1/1098 ,  A61M1/12 ,  A61M1/122 ,  A61M1/125 ,  A61M1/127

摘要： Mechanical circulatory supports configured to operate in series with the native heart are disclosed. In an embodiment, a centrifugal pump is used. In an embodiment, inlet and outlet ports are connected into the aorta and blood flow is diverted through a lumen and a centrifugal pump between the inlet and outlet ports. The supports may create a pressure rise between about 40-80 mmHg, and maintain a flow rate of about 5 L/min. The support may be configured to be inserted in a collinear manner with the descending aorta. The support may be optimized to replicate naturally occurring vortex formation within the aorta. Diffusers of different dimensions and configurations, such as helical configuration, and/or the orientation of installation may be used to optimize vortex formation. The support may use an impeller which is electromagnetically suspended, stabilized, and rotated to pump blood.

公开(公告)号：US20170173236A1

公开(公告)日：2017-06-22

申请号：US15381777

申请日：2016-12-16

申请人： HeartWare, Inc.

发明人： Lance Lynn ANDRUS

IPC分类号： A61M1/10 ,  A61M1/12 ,  A61F2/24 ,  A61B17/32

CPC分类号： A61M1/1008 ,  A61B17/320016 ,  A61B2017/00247 ,  A61B2017/320052 ,  A61F2/2409 ,  A61F2/2427 ,  A61M1/1098 ,  A61M1/122 ,  A61M2039/244 ,  A61M2210/125

摘要： A mounting element defining a bore, the mounting element being configured to mount to an exterior surface of an organ of a patient. A one way valve sized to be received and retained within the bore of the mounting element is included, the one way valve having an open position and a closed position. The one way valve substantially occludes the bore when the valve is in the closed position. The one way valve is biased in the closed position. A plug having a lumen extending there through is included, the plug being configured to be releasably inserted through at least a portion of the one way valve. The plug is configured to transition the one way valve from the closed position to the open position and to maintain the one way valve in the open position when the plug is inserted within the bore.

公开(公告)号：US09682180B2

公开(公告)日：2017-06-20

申请号：US12945890

申请日：2010-11-14

申请人： Carine Hoarau ,  John Duc Nguyen ,  Steven H. Reichenbach ,  Ruth Eleanor Costa ,  James Badia ,  Donald Lee Hannula

发明人： Carine Hoarau ,  John Duc Nguyen ,  Steven H. Reichenbach ,  Ruth Eleanor Costa ,  James Badia ,  Donald Lee Hannula

IPC分类号： A61M1/10 ,  A61M1/12

CPC分类号： A61M1/10 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1098 ,  A61M1/122

摘要： A ventricular assist system and a method of implanting the system are disclosed. The system can have a pump, an inflow conduit, an outflow conduit, attachment ring, ring clamp, and a valvular structure. The attachment ring can be attached to the apex of the heart. The valvular structure can have a flexible, one-way valve in a rigid housing. The inflow conduit can be passed through the valvular structure and the attachment ring into a beating heart with minimal loss of blood. Devices such as slitting tool, coring knife, and/or C-clamp and use of the devices can form part of the system and method for implanting the ventricular assist device.

公开(公告)号：US09486565B2

公开(公告)日：2016-11-08

申请号：US14354922

申请日：2012-10-31

申请人： Berlin Heart GmbH

发明人： Manfred Göllner ,  Ulrich Tim Opfermann ,  Peter Nüsser ,  Andreas Arndt ,  Felix Von Winterfeld

IPC分类号： A61M1/00 ,  A61M1/10 ,  A61M1/12

CPC分类号： A61M1/1008 ,  A61M1/1098 ,  A61M1/12 ,  A61M1/122

摘要： A connecting element for connecting a blood pump or a cannula to a heart, the connecting element including a sealing element, which is designed to at least temporarily close an opening formed in the cardiac wall and to be opened via insertion of a preferably cylindrical object in the direction of an axis of the opening.

摘要翻译： 用于将血液泵或套管连接到心脏的连接元件，所述连接元件包括密封元件，所述密封元件被设计成至少暂时封闭形成在所述心脏壁中的开口并且通过将优选圆柱形物体插入 开口轴线的方向。

公开(公告)号：US20160136343A1

公开(公告)日：2016-05-19

申请号：US14899804

申请日：2014-06-20

申请人： Constantinos ANAGNOSTOPOULOS

发明人： Constantinos ANAGNOSTOPOULOS

IPC分类号： A61M1/10 ,  A61M1/12

CPC分类号： A61M1/1072 ,  A61M1/1005 ,  A61M1/1008 ,  A61M1/106 ,  A61M1/107 ,  A61M1/1074 ,  A61M1/1086 ,  A61M1/1098 ,  A61M1/122 ,  A61M1/125

摘要： A circulatory assist apparatus comprising: an inflatable pumping balloon having a proximal end joined to an elongated balloon catheter, the balloon catheter having a distal end joined to the pumping balloon and a proximal end, separated from the distal end by a length sufficient to extend from within a circulatory lumen to the outside of a patient's body, for receiving positive and negative pressure pulses from a pump to inflate and deflate the pumping balloon; and a radially expandable frame, mounted on one of a segment extending distally from the pumping balloon, the balloon catheter, and a sleeve tube surrounding the balloon catheter. The expandable frame is manipulate to expand within the circulatory lumen, and functions to space apart the inflatable balloon from the circulatory lumen, having a first diameter in a collapsed configuration for intraluminal delivery and a second, larger diameter in an expanded configuration achieved by said manipulation.

摘要翻译： 一种循环辅助装置，包括：充气泵送气囊，其具有连接到细长气囊导管的近端，所述气囊导管具有连接到所述泵送气囊的远端和近端，所述近端与所述远端分离足以从 在患者身体的外部的循环腔内，用于从泵接收正压和负压脉冲以使泵送气囊膨胀和放气; 以及可径向扩张的框架，其安装在从所述泵送气囊向远端延伸的区段中的一个上，所述气囊导管和围绕所述球囊导管的套管。 可扩展框架被操纵以在循环腔内膨胀，并且用于将可膨胀气球与循环腔隔开，以使其具有用于管腔内输送的收缩构造的第一直径和通过所述操作实现的扩张构型中的第二较大直径 。

公开(公告)号：US20150343124A1

公开(公告)日：2015-12-03

申请号：US14808350

申请日：2015-07-24

申请人： Carine Hoarau ,  Steven H. Reichenbach ,  J. Donald Hill ,  George Hsu ,  Andrew R. Miller ,  James Badia ,  Nina Boiadjieva ,  Shuo-Hsiu Chang ,  Philip Haarstad ,  Olga M. Stanescu ,  Stephen Kenneth Sundquist

发明人： Carine Hoarau ,  Steven H. Reichenbach ,  J. Donald Hill ,  George Hsu ,  Andrew R. Miller ,  James Badia ,  Nina Boiadjieva ,  Shuo-Hsiu Chang ,  Philip Haarstad ,  Olga M. Stanescu ,  Stephen Kenneth Sundquist

IPC分类号： A61M1/10 ,  A61B17/10 ,  A61M1/12 ,  A61B17/064 ,  A61B17/072

CPC分类号： A61B17/064 ,  A61B17/072 ,  A61B17/07292 ,  A61B17/10 ,  A61B17/1155 ,  A61B2017/00867 ,  A61B2017/0441 ,  A61B2017/0443 ,  A61B2017/0647 ,  A61B2017/0649 ,  A61B2017/1107 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1087 ,  A61M1/1096 ,  A61M1/1098 ,  A61M1/122

摘要： A coupling system includes an applicator tool and an attachment ring mounted on the applicator tool. Clips are contained within the applicator tool and are deployed through the attachment ring in order to anchor the attachment ring to biological tissue. When deployed, tips of the clips follow a curved trajectory through an annular cuff of the attachment ring and through the underlying tissue. The tips loop back out of the tissue and to a location where they are later trapped or clamped by the attachment ring. While the tips are trapped or clamped, the applicator tool cinches the clips by pulling rear segments of the clips. Thereafter, the applicator tool disconnects from the attachment ring which remains anchored to the tissue and serves as a coupling for a cannula. The cannula can have movable lock members that secure it to the attachment ring.

摘要翻译： 联接系统包括涂抹器工具和安装在涂抹器工具上的附接环。 夹子被包含在施用器工具内并且通过附接环展开，以便将附接环锚定到生物组织。 当部署时，夹子的尖端沿着弯曲的轨迹穿过连接环的环形箍并穿过下面的组织。 尖端从组织回到一个位置，在这些位置，它们随后被附接环卡住或夹紧。 当尖端被夹住或夹紧时，涂抹器工具通过拉动夹子的后部片段来夹紧夹子。 此后，涂抹器工具与保持锚定到组织​​的附接环断开，并用作插管的联接器。 套管可以具有将其固定到附接环的可移动的锁定构件。

公开(公告)号：US20150250935A1

公开(公告)日：2015-09-10

申请号：US14636259

申请日：2015-03-03

申请人： Medtronic Vascular Galway

发明人： Marc Anderson ,  Declan Costello ,  Marian Costello ,  Paul Devereux ,  Niall Duffy ,  John Gallagher ,  John Milroy

IPC分类号： A61M1/12 ,  A61F2/82 ,  A61M1/10

CPC分类号： A61M1/122 ,  A61F2/82 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1025 ,  A61M1/1098 ,  A61M1/125 ,  A61M2210/125

摘要： The invention features modular implantable ventricular assist devices configured to be, at least in part, assembled within a patient. The devices generally include a pump assembly and an expandable frame. The frame is configured to engage tissue of a patient when implanted. The pump assembly is configured to be operably coupled to the frame when the frame is implanted and in the expanded configuration.

摘要翻译： 本发明的特征在于模块化可植入心室辅助装置，其被配置为至少部分地组装在患者体内。 这些装置通常包括泵组件和可扩展框架。 框架被配置为在植入时接合患者的组织。 泵组件被构造成当框架被植入并且处于膨胀构型时可操作地联接到框架。

公开(公告)号：US20150182679A1

公开(公告)日：2015-07-02

申请号：US14415945

申请日：2013-07-19

申请人： President and Fellows of Harvard College ,  California Institute of Technology

发明人： Kevin Kit Parker ,  Josue A. Goss ,  Sung-Jin Park ,  Andrew Keith Capulli ,  Holly A. McIlwee ,  Janna C. Nawroth ,  John O. Dabiri

IPC分类号： A61M1/10 ,  A61F2/24 ,  G01N33/50 ,  A61M1/12

CPC分类号： A61M1/1003 ,  A61F2/2415 ,  A61M1/1037 ,  A61M1/1053 ,  A61M1/1098 ,  A61M1/12 ,  A61M1/122 ,  A61M1/127 ,  G01N33/5061 ,  G01N2500/04 ,  G01N2500/10 ,  Y10T29/49405

摘要： The present invention provides tissue-engineered pumps and valves, methods of fabricating such pumps and valves, and methods of use of such pumps and valves.

摘要翻译： 本发明提供组织工程泵和阀，制造这种泵和阀的方法，以及这种泵和阀的使用方法。

公开(公告)号：US20150119633A1

公开(公告)日：2015-04-30

申请号：US14568448

申请日：2014-12-12

申请人： COOK MEDICAL TECHNOLOGIES LLC

发明人： Kenneth Haselby ,  Brian D. Choules ,  Blayne A. Roeder ,  Richard B. Sisken ,  David Eric Orr ,  James D. Purdy ,  Steven J. Charlebois ,  David D. Grewe ,  Neal E. Fearnot ,  Alan R. Leewood

IPC分类号： A61M1/12

CPC分类号： A61M1/125 ,  A61B5/076 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/6862 ,  A61B5/6876 ,  A61B5/6882 ,  A61F2/0077 ,  A61F2/2418 ,  A61F2/2475 ,  A61F2/86 ,  A61F2002/068 ,  A61F2002/8486 ,  A61F2220/0016 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/005 ,  A61F2230/0071 ,  A61F2230/008 ,  A61M1/1006 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1098 ,  A61M1/122 ,  A61M1/3653 ,  A61M1/3659

摘要： A method of attaching an intravascular device to a vessel wall of a body vessel is disclosed. The attachment system includes an intravascular device and biological attachment material connected to the intravascular device. The biological attachment material is configured to attach the intravascular device to the vessel wall.

摘要翻译： 公开了一种将血管内装置附接到身体血管的血管壁的方法。 附件系统包括连接到血管内装置的血管内装置和生物附着材料。 生物附着材料构造成将血管内装置附接到血管壁。