中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

12 records (took 0.02 seconds)

    COATED IMPLANTABLE MEDICAL DEVICE
    6.
    发明申请
    COATED IMPLANTABLE MEDICAL DEVICE 审中-公开
    涂层可植入医疗器械

    公开(公告)号：US20150150696A1

    公开(公告)日：2015-06-04

    申请号：US14622294

    申请日：2015-02-13

    Applicant: Cook Medical Technologies LLC

    Inventor： Brian L. Bates ,  Anthony O. Ragheb ,  Neal E. Fearnot ,  Thomas G. Kozma ,  William D. Voorhees, III

    IPC: A61F2/82 ,  A61L31/16 ,  A61L31/10

    CPC classification number: A61F2/82 ,  A61F2210/0076 ,  A61F2250/0067 ,  A61F2250/0068 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/416 ,  A61L2420/06 ,  A61L2420/08 ,  C08L29/04

    Abstract: Bioactive-coated medical devices are provided, including coated vascular stents. The medical device coating can include a coating layer posited over at least a portion of the medical device surface, and can include a butyl methacrylate polymer or an ethylene-vinyl acetate copolymer in combination with a bioactive material that can function as both an immunosuppressive agent and an antiproliferative agent. Optionally, multilayer coatings can further include an adhesion promoting layer comprising parylene positioned between the coating layer and the medical device surface, a porous layer comprising butyl methacrylate positioned over at least a portion of the coating layer, or both. The coating layer preferably comprises between about 0.5 and 2.0 μg/mm2 of the bioactive material on the outer surface of the medical device. The bioactive material can be absorbed into the coating layer, which can have a thickness of between about 0.5 μm to about 5 μm.

    Abstract translation: 提供生物活性涂层医疗器械，包括涂层血管支架。 医疗器械涂层可以包括位于医疗器械表面的至少一部分上的涂层，并且可以包括甲基丙烯酸丁酯聚合物或乙烯 - 乙酸乙烯酯共聚物与可以用作免疫抑制剂和生物活性物质的生物活性材料 抗增生剂。 任选地，多层涂层还可以包括粘合促进层，其包括定位在涂层和医疗器件表面之间的聚对二甲苯，包含位于涂层的至少一部分上的甲基丙烯酸丁酯的多孔层，或两者。 涂层优选在医疗装置的外表面上包含约0.5至2.0μg/ mm 2的生物活性材料。 生物活性物质可以被吸收到涂层中，其可以具有约0.5μm至约5μm的厚度。

    COATED MEDICAL DEVICE
    7.
    发明申请
    COATED MEDICAL DEVICE 审中-公开

    公开(公告)号：US20190351197A9

    公开(公告)日：2019-11-21

    申请号：US15810721

    申请日：2017-11-13

    Applicant: Cook Medical Technologies LLC

    Inventor： Brian L. Bates ,  Anthony O. Ragheb ,  Joseph M. Stewart, IV ,  William J. Bourdeau ,  Brian D. Choules ,  James D. Purdy ,  Neal E. Fearnot

    IPC: A61M25/10 ,  A61L29/08 ,  A61F2/844 ,  A61F2/958 ,  A61L27/54 ,  A61F2/82 ,  A61L29/16 ,  A61L31/16

    Abstract: A coated medical device (10) including a structure (12) adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material (14) having a bioactive material layer (18) disposed thereon. The medical device is preferably an implantable stent or balloon (26) of which the bioactive material layer is deposited thereon. The stent can be positioned around the balloon and another layer of the bioactive material posited over the entire structure and extending beyond the ends of the positioned stent. The ends of the balloon extend beyond the ends of the stent and include the bioactive material thereon for delivering the bioactive material to the cells of a vessel wall coming in contact therewith. The balloon further includes a layer of hydrophilic material (58) positioned between the base and bioactive material layers of the balloon.

    CATHETER SYSTEMS AND METHODS USEFUL FOR CELL THERAPY
    9.
    发明申请
    CATHETER SYSTEMS AND METHODS USEFUL FOR CELL THERAPY 有权
    导管系统和用于细胞治疗的方法

    公开(公告)号：US20130338637A1

    公开(公告)日：2013-12-19

    申请号：US13910693

    申请日：2013-06-05

    Applicant: Muffin Incorporated ,  Cook Medical Technologies LLC

    Inventor： Frank J. Fischer, JR. ,  James R. Randolph ,  Neal E. Fearnot ,  Jimmy L. Taylor, JR. ,  Gary Bradford Shirley

    IPC: A61M25/10

    CPC classification number: A61M25/1011 ,  A61B34/20 ,  A61M25/0026 ,  A61M25/0041 ,  A61M25/0068 ,  A61M25/007 ,  A61M25/10 ,  A61M37/0092 ,  A61M2025/0003 ,  A61M2025/0004 ,  A61M2025/0042 ,  A61M2025/1015 ,  A61M2025/1052 ,  A61M2025/1061 ,  A61M2025/1093

    Abstract: Described in one aspect is a multi-pressure monitoring system for cell or other therapy includes a first catheter having a first lumen for accepting a treatment device, a second lumen for inflating a balloon, a pressure sensor for monitoring fluid pressure within the first lumen, and a flow restrictor such as a hemostasis valve for limiting the exchange of fluids into and out of the first lumen while treatment devices are present or exchanged in the first lumen. Also disclosed is a method of using the first catheter with a first pressure monitor coupled to the first pressure sensor along with a second catheter attached to a second pressure sensor coupled to a second pressure monitor. The second catheter is positioned within the first lumen of the first catheter during treatment operations and the first and second pressure monitors are used to verify proper pressures throughout the procedure. Described also are novel methods, systems, and catheters for delivering flowable therapeutic substances, such as viable cellular preparations, to patients.

    Abstract translation: 一方面描述了一种用于细胞或其它疗法的多压力监测系统，包括具有用于接受治疗装置的第一腔的第一导管，用于充气气囊的第二腔，用于监测第一腔内的流体压力的压力传感器， 以及限流器，例如止血阀，用于在第一腔内存在或更换治疗装置的同时限制流体进入和离开第一腔的流体。 还公开了一种使用具有耦合到第一压力传感器的第一压力监测器的第一导管以及连接到耦合到第二压力监测器的第二压力传感器的第二导管的方法。 在治疗操作期间，第二导管定位在第一导管的第一腔内，并且在整个过程中使用第一和第二压力监测器来验证适当的压力。 还描述了用于向患者递送可流动治疗物质（例如活细胞制剂）的新颖方法，系统和导管。

Patent Agency Ranking