公开(公告)号：US09347915B2

公开(公告)日：2016-05-24

申请号：US14619878

申请日：2015-02-11

Applicant: INSTITUTE CURIE ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S)

Inventor： Jean-Louis Viovy ,  Valessa Barbier

IPC: G01N27/447 ,  C08F251/00 ,  C08F265/04 ,  C08F265/10 ,  C08F287/00 ,  C08F297/00 ,  C08F297/02

CPC classification number: G01N27/44747 ,  C08F251/00 ,  C08F265/04 ,  C08F265/10 ,  C08F287/00 ,  C08F297/00 ,  C08F297/026

Abstract: An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.

Abstract translation: 一种用于在具有壁或用于处理元件的壁的元件中分析，纯化或分离物质的水性液体介质。 介质至少包括由几个聚合物链段组成的聚合物。 聚合物是不规则的嵌段共聚物或不规则梳状聚合物类型，并且在不同化学或拓扑性质的聚合链段之间平均具有至少三个连接点。 介质可以用于分析，纯化或分离物质的方法和用于处理在流体的流体和/或物质中包含的物质在流体的保存，输送，分析，纯化或分离过程中的物质和方法。

公开(公告)号：US20160083666A1

公开(公告)日：2016-03-24

申请号：US14787087

申请日：2014-04-23

Applicant: LIEBHERR-AEROSPACE TOULOUSE SAS ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) ,  UNIVERSITÉ PAUL SABATIER TOULOUSE III

Inventor： Souphiane RAHOUI ,  Jean-Pierre BONINO ,  Viviane TURQ-PERRUSSEL ,  Jerome ROCCHI

IPC: C10M103/02 ,  F16C33/16 ,  B05D5/08 ,  B05D3/02 ,  C23C18/12 ,  B05D7/14

CPC classification number: C10M103/02 ,  B05D3/0254 ,  B05D5/08 ,  B05D7/14 ,  B05D2601/20 ,  C10M2201/0413 ,  C23C18/04 ,  C23C18/1216 ,  C23C18/122 ,  C23C18/1241 ,  C23C18/1254 ,  C23C18/1275 ,  C23C18/1279 ,  F16C33/16 ,  Y02T50/6765

Abstract: A process for manufacturing a part provided with a lubricating surface coating (10), in which: a composition is prepared that includes at least one precursor having at least one organic group, the composition is deposited on the part, a heat treatment is carried out, wherein the heat treatment of the coating is carried out at a temperature above 220° C., so as to form a lubricating surface coating (10) formed of an at least partially inorganic solid network incorporating solid carbon in at least one lubricating allotropic form in the dispersed state and trapped within the solid network. A part, such as a foil of a foil bearing (1) obtained by the process, a turbomachine, such as a turbomachine for a fuel cell, including such a part, and an aircraft cabin air-conditioning system including at least one such turbomachine are also described.

Abstract translation: 一种制造具有润滑表面涂层（10）的部件的方法，其中：制备包含至少一种具有至少一个有机基团的前体的组合物，该组合物沉积在该部件上，进行热处理 ，其中所述涂层的热处理在高于220℃的温度下进行，以形成由至少部分无机的固体网络形成的润滑表面涂层（10），所述固体网络包含至少一种润滑同素异形体形式的固体碳 处于分散状态并被困在固网中。 诸如通过该方法获得的箔轴承（1）的箔的部件，包括这种部件的涡轮机，例如用于燃料电池的涡轮机，以及包括至少一个这样的涡轮机的飞机机舱空调系统 也被描述。

公开(公告)号：US20160030599A1

公开(公告)日：2016-02-04

申请号：US14776342

申请日：2014-03-13

Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)

Inventor： Eva Jakab Toth ,  Stéphane Petoud ,  Sara Lacerda ,  Célia Bonnet

IPC: A61K49/00 ,  A61K31/136 ,  A61K31/4745 ,  A61K31/704

CPC classification number: A61K49/0084 ,  A61K31/136 ,  A61K31/137 ,  A61K31/4745 ,  A61K31/704 ,  A61K47/6911 ,  A61K47/6917 ,  A61K49/008

Abstract: The present invention relates to particles, useful for drug release detection, comprising: at least one luminescent metal complex of formula [Ln].[L], wherein: Ln is a lanthanide ion, L is an organic ligand comprising a hydrophilic unit with at least 6 chelating groups chosen from the group consisting of hydroxyl, carboxyl, optionally in the carboxylate form, carbonyl, ether, phosphonate, phosphinate, thiolate, amino and imino functions, and at least one drug comprising a conjugated aromatic system, wherein said drug is not covalently bonded to the metal complex, said particle having a size comprised from 3 nm to 2000 nm, and wherein the distribution of the metal complex and the drug within the particle is such that the mean distance between a drug molecule and a metal complex is less than 15 nm.

Abstract translation: 本发明涉及用于药物释放检测的颗粒，其包含：至少一种式[Ln]的发光金属络合物[L]，其中：Ln是镧系元素离子，L是包含亲水单元的有机配体， 选自羟基，羧基，任选以羧酸盐形式，羰基，醚，膦酸盐，次膦酸盐，硫醇盐，氨基和亚氨基官能团的至少6个螯合基团，和至少一种包含共轭芳族体系的药物，其中所述药物是 所述颗粒具有3nm至2000nm的尺寸，并且其中金属络合物和药物在颗粒内的分布使得药物分子和金属络合物之间的平均距离为 小于15nm。

公开(公告)号：US20160025577A1

公开(公告)日：2016-01-28

申请号：US14811307

申请日：2015-07-28

Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) ,  ECOLE NATIONALE SUPERIEURE DE MECANIQUE ET DES MICROTECHNIQUES

Inventor： Bruno FRANCOIS ,  Sylvain BALLANDRAS ,  Denny RICHTER

IPC: G01K11/26

CPC classification number: G01K11/265

Abstract: This sensor, comprises: a first surface acoustic wave device, comprising a first piezoelectric substrate, formed from a (YXw/t)/φ/θ/ψ cut of a Langasite crystal, where φ is equal to 0±5° is equal to 55±20° and ψ is equal to 32.5±7.5° and a first resonator having a first transducer laying on a first propagation surface and having two sets of interdigitated first electrodes formed from an electrically conductive material having a high melting temperature; and a second surface acoustic wave device, comprising a second piezoelectric substrate, formed from a (YXw/t)/φ/θ/ψ cut of a Langasite crystal, where φ is equal to 0±5°, θ is equal to 5±20° and ψ is equal to 0±7.5°, and a second resonator having a second transducer laying on a second propagation surface and having two sets of interdigitated second electrodes formed from an electrically conductive material having a high melting temperature; said first and second surface acoustic wave devices being independent one from the other in terms of surface acoustic wave propagation.

Abstract translation: 该传感器包括：第一弹性表面波器件，包括由朗氏硅酸盐晶体的（YXw / t）/ψ切割形成的第一压电基片， 等于0±5°等于55±20°，ψ等于32.5±7.5°，第一谐振器具有放置在第一传播表面上的第一传感器，并且具有两组交错的第一电极，由导电 熔点高的材料; 以及第二表面声波装置，其包括第二压电基片，所述第二压电基片由朗氏硅酸盐晶体的（YXw / t）/ψ切割形成; 等于0±5°，＆thetas; 等于5±20°，ψ等于0±7.5°，第二谐振器具有放置在第二传播表面上的第二传感器，并且具有由具有高熔融温度的导电材料形成的两组叉指第二电极 ; 所述第一和第二表面声波装置在表面声波传播方面彼此独立。

公开(公告)号：US09193699B2

公开(公告)日：2015-11-24

申请号：US14349529

申请日：2012-10-04

Applicant: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) ,  UNIVERSITE D'AIX-MARSEILLE ,  L'INSTITUT PAOLI CALMETTE

Inventor： Marc Lopez ,  Yves Collette ,  Lynda Mezil ,  Jean-Michel Brunel ,  Sebastien Combes

IPC: C07D279/12

CPC classification number: C07D279/12

Abstract: Provided are compounds of formula (I): wherein R1, R2, R3, R4 and R5 are independently selected from the group comprising, inter aliae, H, optionally substituted, branched or linear C1-C12 alkyl, halogen atom and C1-C12 haloalkyl, and wherein A represents a single bond or an optionally substituted C1-C6 alkylene radical, notably useful for the treatment of human cancers.

Abstract translation: 提供式（I）的化合物：其中R 1，R 2，R 3，R 4和R 5独立地选自包括H，任选取代的，支链或直链的C 1 -C 12烷基，卤素原子和C 1 -C 12卤代烷基 ，并且其中A表示单键或任选取代的C1-C6亚烷基，特别可用于治疗人类癌症。

公开(公告)号：US20150328253A1

公开(公告)日：2015-11-19

申请号：US14442884

申请日：2013-11-15

Applicant: UNIVERSITÉ BLAISE PASCAL - CLERMONT II ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)

Inventor： Philippe MICHAUD ,  Celine LAROCHE ,  Aurore VILLAY ,  Michael ROUSSEL ,  Marie DIOGON ,  Hicham EL ALAOUI ,  Frederic DELBAC

IPC: A61K31/737 ,  A61K36/04 ,  A23K1/18 ,  A61K36/03 ,  A23L1/30 ,  A23K1/16 ,  A61K35/748 ,  A61K36/05

CPC classification number: A61K35/748 ,  A23K20/147 ,  A23K20/163 ,  A23K50/90 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/737 ,  A61K36/03 ,  A61K36/04 ,  A61K36/05 ,  Y02A50/492 ,  A61K2300/00 ,  A23V2200/30 ,  A23V2250/202 ,  A23V2250/50

Abstract: The invention concerns a composition made from at least one sulphated polysaccharide, in particular from an algae, and combined with at least one food ingredient. This composition can be used, in particular, in the field of food or in the treatment or prevention of an infection caused by microsporidia in humans or animals. It has useful properties as an antiparasitic agent in humans or animals; for the treatment or prevention of an infection caused by at least one microsporidia in humans or animals; in particular for the treatment or prevention of an infection caused in bees by the microsporidia Nosema, preferably Nosema ceranae or Nosema apis, or indeed for stimulating the immune defences of bees.

Abstract translation: 本发明涉及由至少一种硫酸化多糖特别是来自藻类制成并与至少一种食物成分组合的组合物。 该组合物特别可用于食品领域或用于治疗或预防由人或动物中的微孢子虫引起的感染。 它在人或动物中作为抗寄生虫剂具有有用的性质; 用于治疗或预防由人或动物中的至少一种微孢子虫引起的感染; 特别是用于治疗或预防由微孢子虫Nosema，优选Nosema ceranae或Nosema apis引起的感染的感染，或者实际上用于刺激蜜蜂的免疫防御。

公开(公告)号：US20150326021A1

公开(公告)日：2015-11-12

申请号：US14412542

申请日：2013-07-01

Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)

Inventor： Marc COUSINEAU

IPC: H02J4/00

CPC classification number: H02J4/00 ,  H02M3/1584 ,  H02M7/483 ,  H02M2001/0025 ,  Y10T307/549

Abstract: A static converter with parallel architecture or series architecture comprises a plurality of switching cells, arranged in parallel or in series, and controlled in a decentralized manner by associated control modules, strung together according to a loop by a series of communication links.Each control module comprises a single and different local unit for generating the triangular carrier of the module which controls the positioning of its interleaving phase as a function only of the signals of the triangular carriers of the two adjacent modules.Each control module comprises a local unit for balancing the currents of branches and/or a unit for internal regulation of the output voltage of AVP type, or a local unit for balancing the cell voltages and/or a unit for internal regulation of the input current or output current of the ACP type.

Abstract translation: 具有并行架构或串联架构的静态转换器包括并联或串联布置的多个开关单元，并且通过相关联的控制模块以分散的方式进行控制，所述控制模块通过一系列通信链路根据环路串联在一起。 每个控制模块包括单个和不同的本地单元，用于产生模块的三角形载波，其仅控制两个相邻模块的三角形载波的信号来控制其交错相位的定位。 每个控制模块包括用于平衡分支电流和/或用于内部调节AVP类型的输出电压的单元的本地单元或用于平衡单元电压的本地单元和/或用于输入电流的内部调节的单元 或ACP型的输出电流。

公开(公告)号：US20150310166A1

公开(公告)日：2015-10-29

申请号：US14648250

申请日：2013-11-26

Applicant: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) ,  UNIVERSITÉ DE STRASBOURG

Inventor： Hinrich GRONEMEYER ,  Marco Antonio MENDOZA PARRA

IPC: G06F19/22 ,  G06F17/30

CPC classification number: G16B30/00 ,  G06F16/2365 ,  G16B40/00

Abstract: A method processes data for evaluating quality level of an original dataset. The original dataset is obtained from an automated sequencing of a chain of nucleotides and represents a plurality of total mapped reads. The method includes sampling of a plurality of total mapped reads of the original dataset to produce a subset of mapped reads. The method also includes computing a dispersion indicator for the subset. The dispersion indicator represents divergence between an actual read count intensity and a theoretical read count intensity. The actual read count corresponds to the number of sampled mapped reads. The theoretical read count corresponds to a theoretical number of sampled mapped reads, which does not depend on the current sampling.

Abstract translation: 一种方法处理用于评估原始数据集的质量水平的数据。 原始数据集从核苷酸链的自动测序获得，并且表示多个总映射读数。 该方法包括对原始数据集的多个总映射读取进行采样以产生映射读取的子集。 该方法还包括计算该子集的色散指示符。 色散指示符表示实际读取计数强度和理论读取计数强度之间的差异。 实际读数对应于采样映射读数的数量。 理论读数对应于不依赖于当前采样的采样映射读取的理论数量。

公开(公告)号：US09051520B2

公开(公告)日：2015-06-09

申请号：US13661338

申请日：2012-10-26

Applicant: UNIVERSITE DE POITIERS ,  C.N.R.S. ,  IFP Energies nouvelles

Inventor： Nuno Miguel Rocha Batalha ,  Ludovic Pinard ,  Francisco Manuel Da Silva Lemos ,  Fernando Manuel Ramoa Ribeiro ,  Emmanuelle Guillon ,  Christophe Bouchy

IPC: C10G47/18 ,  C10G47/20 ,  B01J35/10 ,  B01J29/72 ,  B01J29/70 ,  B01J29/76 ,  B01J29/74 ,  B01J29/78 ,  B01J35/02

CPC classification number: C10G47/18 ,  B01J29/7007 ,  B01J29/7215 ,  B01J29/7415 ,  B01J29/7615 ,  B01J29/7815 ,  B01J35/023 ,  B01J35/1038 ,  B01J2229/20 ,  B01J2229/42 ,  B01J2229/64 ,  C10G47/20 ,  C10G2300/1022 ,  C10G2400/04

Abstract: A process for the production of middle distillates comprising at least one hydrocracking stage that oligomerizes a paraffinic feedstock produced by Fischer-Tropsch synthesis, the process using a catalyst that comprises at least one hydrogenating-dehydrogenating metal that is selected from the group that is formed by the metals of group VIB and group VIII of the periodic table, by themselves or in a mixture, and a substrate that comprises a beta zeolite in the form of crystallites with a mean size that is less than 100 nm dispersed in at least one porous mineral matrix, whereby the beta zeolite has a mesopore volume of less than 0.4 ml/g.

Abstract translation: 一种生产中间馏分的方法，其包括至少一个加氢裂化阶段，该加氢裂化阶段使由费 - 托合成产生的链烷烃原料低聚，该方法使用包含至少一种氢化脱氢金属的催化剂，所述催化剂选自由 元素周期表第VIB族和第VIII族的金属本身或混合物，以及底物，其包含分散在至少一种多孔矿物中的平均粒度小于100nm的微晶形式的β沸石 基质，其中β沸石的中孔体积小于0.4ml / g。

公开(公告)号：US20150155598A1

公开(公告)日：2015-06-04

申请号：US14550884

申请日：2014-11-21

Applicant: California Institute of Technology ,  Centre National De La Recherche Scientifique (C.N.R.S.)

Inventor： Rachid YAZAMI

IPC: H01M10/0567 ,  H01M10/08 ,  H01M10/26 ,  H01M10/22 ,  H01M4/583 ,  H01M10/0561

CPC classification number: H01M10/0567 ,  H01M4/38 ,  H01M4/582 ,  H01M4/583 ,  H01M4/5835 ,  H01M4/60 ,  H01M4/604 ,  H01M4/606 ,  H01M4/608 ,  H01M6/04 ,  H01M6/045 ,  H01M6/166 ,  H01M10/04 ,  H01M10/0561 ,  H01M10/0568 ,  H01M10/08 ,  H01M10/22 ,  H01M10/26 ,  H01M10/36 ,  H01M2300/0002 ,  H01M2300/0017 ,  Y02E60/12

Abstract: Electrochemical cells of the present invention are versatile and include primary and secondary cells useful for a range of important applications including use in portable electronic devices. Electrochemical cells of the present invention also exhibit enhanced safety and stability relative to conventional state of the art primary lithium batteries and lithium ion secondary batteries. For example, electrochemical cells of the present invention include secondary electrochemical cells using anion charge carriers capable of accommodation by positive and negative electrodes comprising anion host materials, which entirely eliminate the need for metallic lithium or dissolved lithium ion in these systems.

Abstract translation: 本发明的电化学电池是通用的，并且包括可用于一系列重要应用的一次和二次电池，包括用于便携式电子设备中。 本发明的电化学电池相对于现有技术的一次锂电池和锂离子二次电池也表现出增强的安全性和稳定性。 例如，本发明的电化学电池包括使用能够由包括阴离子主体材料的正极和负极调节的阴离子电荷载体的二次电化学电池，其完全不需要这些系统中的金属锂或溶解的锂离子。